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Volumn 56, Issue 4, 2003, Pages 166-187

High-resolution joint linkage disequilibrium and linkage mapping of quantitative trait loci based on sibship data

Author keywords

IBD; LD mapping; Linkage analysis; QTL; Variance component models

Indexed keywords

ACCURACY; ARTICLE; CALCULATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GENETIC TRAIT; HUMAN; LINKAGE ANALYSIS; MARKER GENE; PEDIGREE; POPULATION RESEARCH; QUANTITATIVE TRAIT LOCUS; SIBLING; SIMULATION; THEORETICAL MODEL;

EID: 1642604056     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076392     Document Type: Article
Times cited : (12)

References (54)
  • 1
    • 0033909546 scopus 로고    scopus 로고
    • A general test of association for quantitative traits in nuclear families
    • Abecasis GR, Cardon LR, Cookson WOC (2000) A general test of association for quantitative traits in nuclear families. Am J Hum Genet 66:279-292.
    • (2000) Am J Hum Genet , vol.66 , pp. 279-292
    • Abecasis, G.R.1    Cardon, L.R.2    Cookson, W.O.C.3
  • 3
    • 0034987323 scopus 로고    scopus 로고
    • The power to detect linkage disequilibrium with quantitative traits in selected samples
    • Abecasis GR, Cookson WOC, Cardon LR (2001) The power to detect linkage disequilibrium with quantitative traits in selected samples. Am J Hum Genet 68:1463-1474.
    • (2001) Am J Hum Genet , vol.68 , pp. 1463-1474
    • Abecasis, G.R.1    Cookson, W.O.C.2    Cardon, L.R.3
  • 4
    • 0031028361 scopus 로고    scopus 로고
    • Transmission-disequilibrium tests for quantitative traits
    • Allison DB (1997) Transmission-disequilibrium tests for quantitative traits. Am J Hum Genet 60:676-690.
    • (1997) Am J Hum Genet , vol.60 , pp. 676-690
    • Allison, D.B.1
  • 5
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative trait linkage analysis in general pedigrees
    • Almasy L, Blangero J (1998) Multipoint quantitative trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 6
    • 0032759018 scopus 로고    scopus 로고
    • Quantitative trait locus detection using combined linkage/disequilibrium analysis
    • Almasy L, Williams JT, Dyer TD, Blangero J (1999) Quantitative trait locus detection using combined linkage/disequilibrium analysis. Genet Epidemiol 17 (Suppl 1):S31-S36.
    • (1999) Genet Epidemiol , vol.17 , Issue.1 SUPPL.
    • Almasy, L.1    Williams, J.T.2    Dyer, T.D.3    Blangero, J.4
  • 7
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing linkage in pedigrees
    • Amos CI (1994) Robust variance-components approach for assessing linkage in pedigrees. Am J Hum Genet 54:534-543.
    • (1994) Am J Hum Genet , vol.54 , pp. 534-543
    • Amos, C.I.1
  • 9
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic map: Individual and sex-specific variation in recombination
    • Broman KW, Murray JC, Sheffield VC, White RL, Weber JL (1998) Comprehensive human genetic map: Individual and sex-specific variation in recombination. Am J Hum Genet 63:861-869.
    • (1998) Am J Hum Genet , vol.63 , pp. 861-869
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3    White, R.L.4    Weber, J.L.5
  • 10
    • 0033925437 scopus 로고    scopus 로고
    • A sibpair regression model of linkage disequilibrium for quantitative traits
    • Cardon LR (2000) A sibpair regression model of linkage disequilibrium for quantitative traits. Hum Hered 50:350-358.
    • (2000) Hum Hered , vol.50 , pp. 350-358
    • Cardon, L.R.1
  • 11
    • 84979425295 scopus 로고
    • Genetic analysis workshop III: Sib pair analyses to determine linkage groups and to order loci
    • Elston RC, Keats BJB (1985) Genetic analysis workshop III: sib pair analyses to determine linkage groups and to order loci. Genet Epidemiol 2:211-213.
    • (1985) Genet Epidemiol , vol.2 , pp. 211-213
    • Elston, R.C.1    Keats, B.J.B.2
  • 13
    • 0036802676 scopus 로고    scopus 로고
    • High resolution mapping of quantitative trait loci by linkage disequilibrium analysis
    • Fan R, Xiong M (2002) High resolution mapping of quantitative trait loci by linkage disequilibrium analysis. Eur J Hum Genet 10:607-615.
    • (2002) Eur J Hum Genet , vol.10 , pp. 607-615
    • Fan, R.1    Xiong, M.2
  • 14
    • 0037301010 scopus 로고    scopus 로고
    • Combined high resolution linkage and association mapping of quantitative trait loci
    • Fan R, Xiong M (2003) Combined high resolution linkage and association mapping of quantitative trait loci. Eur J Hum Genet 11:125-137.
    • (2003) Eur J Hum Genet , vol.11 , pp. 125-137
    • Fan, R.1    Xiong, M.2
  • 15
    • 0028236482 scopus 로고
    • A sibpair approach to interval mapping of quantitative trait loci
    • Fulker DW, Cardon LR (1994) A sibpair approach to interval mapping of quantitative trait loci. Am J Hum Genet 54:1092-1103.
    • (1994) Am J Hum Genet , vol.54 , pp. 1092-1103
    • Fulker, D.W.1    Cardon, L.R.2
  • 16
    • 0028947057 scopus 로고
    • Multiple interval mapping of quantitative trait loci, using sibpairs
    • Fulker DW, Cherny SS, Cardon LR (1995) Multiple interval mapping of quantitative trait loci, using sibpairs. Am J Hum Genet 56:1224-1233.
    • (1995) Am J Hum Genet , vol.56 , pp. 1224-1233
    • Fulker, D.W.1    Cherny, S.S.2    Cardon, L.R.3
  • 17
    • 0033366671 scopus 로고    scopus 로고
    • Combined linkage and association sibpair analysis for quantitative traits
    • Fulker DW, Cherny SS, Sham PC, Hewitt JK (1999) Combined linkage and association sibpair analysis for quantitative traits. Am J Hum Genet 64:259-267.
    • (1999) Am J Hum Genet , vol.64 , pp. 259-267
    • Fulker, D.W.1    Cherny, S.S.2    Sham, P.C.3    Hewitt, J.K.4
  • 18
    • 0033364734 scopus 로고    scopus 로고
    • A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression
    • George V, Tiwari HK, Zhu XF, Elston RC (1999) A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression. Am J Hum Genet 65:236-245.
    • (1999) Am J Hum Genet , vol.65 , pp. 236-245
    • George, V.1    Tiwari, H.K.2    Zhu, X.F.3    Elston, R.C.4
  • 19
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE (1990) Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 47:957-967.
    • (1990) Am J Hum Genet , vol.47 , pp. 957-967
    • Goldgar, D.E.1
  • 20
    • 0026600683 scopus 로고
    • Comparison of a multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits
    • Goldgar DE, Oniki RS (1992) Comparison of a multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits. Am J Hum Genet 50:598-606.
    • (1992) Am J Hum Genet , vol.50 , pp. 598-606
    • Goldgar, D.E.1    Oniki, R.S.2
  • 21
    • 0000874908 scopus 로고    scopus 로고
    • Linkage analysis in the presence of error IV: Joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified
    • Göring HHH, Terwillinger JD (2000) Linkage analysis in the presence of error IV: Joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet 66:1310-1327.
    • (2000) Am J Hum Genet , vol.66 , pp. 1310-1327
    • Göring, H.H.H.1    Terwillinger, J.D.2
  • 23
    • 33646942472 scopus 로고
    • A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
    • Haley CS, Knott SA (1992) A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69:315-324.
    • (1992) Heredity , vol.69 , pp. 315-324
    • Haley, C.S.1    Knott, S.A.2
  • 27
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC (1972) The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 28
    • 0023430504 scopus 로고
    • Gametic disequilibrium measures: Proceed with caution
    • Hedrick PW (1987) Gametic disequilibrium measures: proceed with caution. Genetics 117:331-341.
    • (1987) Genetics , vol.117 , pp. 331-341
    • Hedrick, P.W.1
  • 29
    • 0032470875 scopus 로고    scopus 로고
    • A discordant-sibship test for disequilibrium and linkage: No need for parental data
    • Horvath S, Laird NM (1998) A discordant-sibship test for disequilibrium and linkage: no need for parental data. Am J Hum Genet 63:1886-1897.
    • (1998) Am J Hum Genet , vol.63 , pp. 1886-1897
    • Horvath, S.1    Laird, N.M.2
  • 30
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • The International SNP Map Working Group (2001) A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409:928-933.
    • (2001) Nature , vol.409 , pp. 928-933
  • 31
    • 0027247860 scopus 로고
    • Interval mapping of multiple quantitative trait loci
    • Jansen RC (1993) Interval mapping of multiple quantitative trait loci. Genetics 135:205-211.
    • (1993) Genetics , vol.135 , pp. 205-211
    • Jansen, R.C.1
  • 32
    • 18544381909 scopus 로고    scopus 로고
    • A high resolution recombination map of the human genome
    • Kong A, Gudbjartsson DF, Sainz J et al. (2002) A high resolution recombination map of the human genome. Nat Genet 31:241-247.
    • (2002) Nat Genet , vol.31 , pp. 241-247
    • Kong, A.1    Gudbjartsson, D.F.2    Sainz, J.3
  • 33
    • 0024508964 scopus 로고
    • Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
    • Lander ES, Botstein D (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185-199.
    • (1989) Genetics , vol.121 , pp. 185-199
    • Lander, E.S.1    Botstein, D.2
  • 35
    • 0002907949 scopus 로고
    • The interaction of selection and linkage. I. General considerations; heterotic models
    • Lewontin RC (1964) The interaction of selection and linkage. I. General considerations; heterotic models. Genetics 49:67.
    • (1964) Genetics , vol.49 , pp. 67
    • Lewontin, R.C.1
  • 36
    • 0034787710 scopus 로고    scopus 로고
    • Description of three data sets: Collaborative Study on the Genetics of Asthma (CSGA), the German Affected Sib Pair Study, and the Hutterites of South Dakota
    • Meyers DA, Wjst M, Ober C (2001) Description of three data sets: Collaborative Study on the Genetics of Asthma (CSGA), the German Affected Sib Pair Study, and the Hutterites of South Dakota. Genet Epidemiol 21(suppl 1):S4-S8.
    • (2001) Genet Epidemiol , vol.21 , Issue.1 SUPPL.
    • Meyers, D.A.1    Wjst, M.2    Ober, C.3
  • 37
    • 0033927575 scopus 로고    scopus 로고
    • Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus
    • Monks SA, Kaplan NL (2000) Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus. Am J Hum Genet 66:576-592.
    • (2000) Am J Hum Genet , vol.66 , pp. 576-592
    • Monks, S.A.1    Kaplan, N.L.2
  • 38
    • 0033928381 scopus 로고    scopus 로고
    • Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components
    • Pratt SC, Daly M, Kruglyak L (2000) Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components. Am J Hum Genet 66:1153-1157.
    • (2000) Am J Hum Genet , vol.66 , pp. 1153-1157
    • Pratt, S.C.1    Daly, M.2    Kruglyak, L.3
  • 39
    • 0030827556 scopus 로고    scopus 로고
    • A transmission disequilibrium test for quantitative trait loci
    • Rabinowitz D (1997) A transmission disequilibrium test for quantitative trait loci. Hum Hered 47:342-350.
    • (1997) Hum Hered , vol.47 , pp. 342-350
    • Rabinowitz, D.1
  • 40
    • 0031455778 scopus 로고    scopus 로고
    • Genotype relative-risks and association tests for nuclear families with missing parents
    • Schaid DJ, Li H (1997) Genotype relative-risks and association tests for nuclear families with missing parents. Genet Epidemiol 14:1113-1118.
    • (1997) Genet Epidemiol , vol.14 , pp. 1113-1118
    • Schaid, D.J.1    Li, H.2
  • 41
    • 0032231911 scopus 로고    scopus 로고
    • Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease
    • Schaid DJ, Rowland C (1998) Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease. Am J Hum Genet 63:1492-1506.
    • (1998) Am J Hum Genet , vol.63 , pp. 1492-1506
    • Schaid, D.J.1    Rowland, C.2
  • 42
    • 0027362259 scopus 로고
    • Extended multipoint identity-by-descent analysis of human quantitative traits: Efficiency, power, and modeling considerations
    • Schork N (1993) Extended multipoint identity-by-descent analysis of human quantitative traits: Efficiency, power, and modeling considerations. Am J Hum Genet 53:1306-1319.
    • (1993) Am J Hum Genet , vol.53 , pp. 1306-1319
    • Schork, N.1
  • 43
    • 84907319426 scopus 로고
    • Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions
    • Self SG, Liang KY (1987) Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions. J Am Stat Assoc 82:605-610.
    • (1987) J Am Stat Assoc , vol.82 , pp. 605-610
    • Self, S.G.1    Liang, K.Y.2
  • 44
    • 0033927466 scopus 로고    scopus 로고
    • Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data
    • Sham PC, Cherny SS, Purcell S, Hewitt JK (2000) Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. Am J Hum Genet 66:1616-1630.
    • (2000) Am J Hum Genet , vol.66 , pp. 1616-1630
    • Sham, P.C.1    Cherny, S.S.2    Purcell, S.3    Hewitt, J.K.4
  • 45
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ (1998) A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet 62:450-458.
    • (1998) Am J Hum Genet , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 47
    • 0033563231 scopus 로고    scopus 로고
    • A genome-wide search for linkage to asthma
    • Wjst M, Fischer G, Immervoll T, et al. (1999) A genome-wide search for linkage to asthma. Genomics 58:1-8.
    • (1999) Genomics , vol.58 , pp. 1-8
    • Wjst, M.1    Fischer, G.2    Immervoll, T.3
  • 48
    • 0036188948 scopus 로고    scopus 로고
    • Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations
    • Wu RL, Ma CX, Casella G (2002) Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations. Genetics 160:779-792.
    • (2002) Genetics , vol.160 , pp. 779-792
    • Wu, R.L.1    Ma, C.X.2    Casella, G.3
  • 49
    • 0033809735 scopus 로고    scopus 로고
    • Combined linkage and linkage disequilibrium mapping for genome screens
    • Xiong MM, Jin L (2000) Combined linkage and linkage disequilibrium mapping for genome screens. Genet Epidemiol 19:211-234.
    • (2000) Genet Epidemiol , vol.19 , pp. 211-234
    • Xiong, M.M.1    Jin, L.2
  • 50
    • 0028810715 scopus 로고
    • A random model approach to interval mapping of quantitative trait loci
    • Xu SZ, Atchley WR (1995) A random model approach to interval mapping of quantitative trait loci. Genetics 141:1189-1197.
    • (1995) Genetics , vol.141 , pp. 1189-1197
    • Xu, S.Z.1    Atchley, W.R.2
  • 51
    • 0034893786 scopus 로고    scopus 로고
    • Quantitative similarity-based association tests using population samples
    • Zhang SL, Zhao HY (2001) Quantitative similarity-based association tests using population samples. Am J Hum Genet 69:601-614.
    • (2001) Am J Hum Genet , vol.69 , pp. 601-614
    • Zhang, S.L.1    Zhao, H.Y.2
  • 52
    • 0034798104 scopus 로고    scopus 로고
    • Population based linkage disequilibrium mapping of QTL: An application to simulated data in an isolated population
    • Zhao J, Li W, Xiong M (2001) Population based linkage disequilibrium mapping of QTL: an application to simulated data in an isolated population. Genet Epidemiol 21 (S1):S655-659.
    • (2001) Genet Epidemiol , vol.21 , Issue.S1
    • Zhao, J.1    Li, W.2    Xiong, M.3
  • 53
    • 1642624669 scopus 로고    scopus 로고
    • Unbiased quantitative population association test
    • Poster 2336
    • Zhao J, Xiong M (2002) Unbiased quantitative population association test. Am J Hum Genet 71(suppl):568, Poster 2336.
    • (2002) Am J Hum Genet , vol.71 , Issue.SUPPL. , pp. 568
    • Zhao, J.1    Xiong, M.2
  • 54
    • 0034108374 scopus 로고    scopus 로고
    • Power comparison of regression methods to test quantitative traits for association and linkage
    • Zhu XF, Elston RC (2000) Power comparison of regression methods to test quantitative traits for association and linkage. Genet Epidemiol 18:322-330.
    • (2000) Genet Epidemiol , vol.18 , pp. 322-330
    • Zhu, X.F.1    Elston, R.C.2


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