Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors

Biochimica et Biophysica Acta - General Subjects

Volumn 1672, Issue 1, 2004, Pages 51-59

  Poliakov, Anton ^a   Johansson, Anja ^a   Åkerblom, Eva ^a   Oscarsson, Karin ^b   Samuelsson, Bertil ^b,c   Hallberg, Anders ^a   Danielson, U Helena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c MEDIVIR AB   (Sweden)

Author keywords

1 aminocyclopropane 1 carboxylic acid; Abu; ACPC; Bovine pancreatic chymotrypsin; BPC; HCV; Hepatitis C virus; HLE; Human leukocyte elastase; Inhibition; L aminobutyric acid; Non structural protein 3; NS3; NS3 protease; Selectivity; Specificity

Indexed keywords

1 AMINOCYCLOPROPANECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; ALPHA KETOTETRAZOLE; CATHEPSIN B; CHYMOTRYPSIN; KETONE DERIVATIVE; LEUKOCYTE ELASTASE; NORVALINE; PHENYLACYLSULFONAMIDE; PROTEINASE INHIBITOR; SERINE PROTEINASE; SULFONAMIDE; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; LEUKOCYTE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

HEPACIVIRUS; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

BOVINAE; HEPATITIS C VIRUS; SUIDAE;

EID: 1642603449     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2004.02.008     Document Type: Article

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