Tetrapeptides as potent protease inhibitors of hepatitis C virus full-length NS3 (protease-helicase/NTPase)

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 12, 2002, Pages 3915-3922

  Johansson, Anja ^a   Poliakov, Anton ^a   Åkerblom, Eva ^a   Lindeberg, Gunnar ^a   Winiwarter, Susanne ^a   Samuelsson, Bertil ^b   Danielson, U Helena ^a   Hallberg, Anders ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MEDIVIR AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYCLOHEXYLGLYCYLGLUTAMYL 2 NAPHTHYLALANYLCYSTEINE; ACETYLCYCLOHEXYLGLYCYLGLUTAMYLGLUTAMYLCYSTEINE; ACETYLGLUTAMYLGLUTAMYLCYSTEINE; CYCLOHEXYLGLYCYLGLUTAMYLGLUTAMYLCYSTEINE; GLUTARYLCYCLOHEXYLGLYCYLGLUTAMYL 2 NAPHTHYLALANYLCYSTEINE; GLUTARYLCYCLOHEXYLGLYCYLGLUTAMYLGLUTAMYLCYSTEINE; GLUTARYLCYCLOHEXYLGLYCYLISOLEUCYL BETA CYCLOHEXYLALANYLCYSTEINE; GLUTARYLGLUTAMYLGLUTAMYLCYSTEINE; HELICASE; PROTEINASE; PROTEINASE INHIBITOR; SUCCINYL 3,3 DIPHENYLALANYLGLUTAMYL 2 NAPHTHYLALANYLCYSTEINE; SUCCINYL 3,3 DIPHENYLALANYLGLUTAMYL BETA (4 BIPHENYL)ALANYLCYSTEINE; SUCCINYL 3,3 DIPHENYLALANYLGLUTAMYL BETA CYCLOHEXYLALANYLCYSTEINE; SUCCINYL 3,3 DIPHENYLALANYLGLUTAMYLGLUTAMYLCYSTEINE; SUCCINYL 3,3 DIPHENYLALANYLGLUTAMYLPHENYLALANYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLGLUTAMYL 2 NAPHTHYLALANINE; SUCCINYLCYCLOHEXYLGLYCYLGLUTAMYL BETA (4 BIPHENYL)ALANYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLGLUTAMYL BETA CYCLOHEXYLALANYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLGLUTAMYLGLUTAMYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLGLUTAMYLLEUCYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLISOLEUCYL BETA CYCLOHEXYLALANYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLISOLEUCYLGLUTAMYLCYSTEINE; SUCCINYLCYCLOHEXYLGLYCYLVALYLGLUTAMYLCYSTEINE; SUCCINYLGLUTAMYLGLUTAMYLCYSTEINE; SUCCINYLLEUCYLGLUTAMYLGLUTAMYLCYSTEINE; SUCCINYLLEUCYLISOLEUCYL BETA CYCLOHEXYLALANYLCYSTEINE; TETRAPEPTIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIRUS PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; ASSAY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; HEPATITIS C; HEPATITIS C VIRUS; IN VITRO STUDY; IONIC STRENGTH; MOLECULAR MODEL; NONHUMAN; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEINASE INHIBITION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; MODELS, MOLECULAR; OLIGOPEPTIDES; OSMOLAR CONCENTRATION; PEPTIDE LIBRARY; PROTEASE INHIBITORS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 0036973337     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00310-3     Document Type: Article

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