NKp44 Triggers NK Cell Activation through DAP12 Association That Is Not Influenced by a Putative Cytoplasmic Inhibitory Sequence

Journal of Immunology

Volumn 172, Issue 2, 2004, Pages 899-906

  Campbell, Kerry S ^a   Yusa, Sei Ichi ^a,b   Kikuchi Maki, Akiko ^a   Catina, Tracey L ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL RECEPTOR; CHIMERIC PROTEIN; CLATHRIN; GAMMA INTERFERON; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; LYSINE; NATURAL CYTOTOXICITY RECEPTOR 2; PERVANADATE; PHENYLALANINE; PHOSPHATASE; PROTEIN NKP44; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL ACTIVATION; CELL INCLUSION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNORECEPTOR TYROSINE BASED INHIBITORY MOTIF; INTERNALIZATION; LEUKEMIA CELL LINE; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS;

EID: 1642536465     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.2.899     Document Type: Article

References (27)

1. Vitale, M., C. Bottino, S. Sivori, L. Sanseverino, R. Castriconi, E. Marcenaro, R. Augugliaro, L. Moretta, and A. Moretta. 1998. NKp44, a novel triggerine surface molecule specifically expressed by activated natural killer cells, is in volved in non-major histocompatibility complex-restricted tumor cell lysis. J. Exp. Med. 187:2065.
2. Cantoni, C., C. Bottino, M. Vitale, A. Pessino, R. Augugliaro, A. Malaspina, S. Parolini, L. Moretta, A. Moretta, and R. Biassoni. 1999. NKp44, a triggering receptor involved in tumor cell lysis by activating human natural killer cells, is a novel member of the immunoglobulm superfamily. J. Exp. Med. 189:787.
3. Moretta, A., C. Bottino, M. Vitale, D. Pende, C. Cantoni, M. C. Mingari, R. Biassoni, and L. Moretta. 2001. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19:197.
4. Biassoni, R., A. Pessino, C. Bottino, D. Pende, L. Moretta, and A. Moretta. 1999. The murine homologue of the human NKp46, a triggering-receptor involved in the induction of natural cytotoxicity. Eur. J. Immunol. 29:1014.
5. Falco, M., C. Cantoni, C. Bottino, A. Moretta, and R. Biassoni. 1999. Identification of the rat homologue of the human NKp46 triggering receptor. Immunol. Lett. 68:411.
6. Pende, D., S. Parolini, A. Pessino, S. Sivori, R. Augugliaro, L. Morelli, E. Marcenaro, L. Accame, A. Malaspina, R. Biassoni, et al. 1999. Identification and molecular characterization of NKp30, a novel triggering, receptor involved in natural cytotoxicity mediated by human natural killer cells. J. Exp. Med. 190:1505.
7. Arnon, T. I., M. Lev, G. Katz, Y. Chernobrov, A. Porgador, and O. Mandelboim. 2001. Recognition of viral hemagglutinins by NKp44 but not by NKp30. Eur. J. Immunol. 31:2080.
8. Mandelboim, O., N. Lieberman, M. Lev, L. Paul, T. I. Arnon, Y. Bushkin, D. M. Davis, J. L. Strominger, J. W. Yewdell, and A. Porgador. 2001. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 409:1055.
9. Songyang, Z., and L. C. Cantley. 1995. Recognition and specificity in protein tyrosine kinase-mediated signalling. Trends Biochem. Sciences. 20:470.
10. Songyang, Z., K. L. Carraway III. M. J. Eck, R. A. Feldman, M. Mohammadl, J. Schlessinger, S. R. Hubbard, D. P. Smith, C. Eng. M. J. Lorenzo, et al. 1995. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373:536
11. Yusa, S., T. L. Catina, and K. S. Campbell. 2002. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J. Immunol. 168:5047.
12. Chevray, P. M., and D. Nathans. 1992. Protein interaction cloning in yeast: identification of in mammalian proteins that react with the leucine zipper of Jun. Proc. Natl. Acad. Sci. USA 89:5789.
13. Golemis, E., J. Gyuris, and R. Brent. 1994. Interaction trap/two-hybrid system to identify interacting proteins. In Current Protocols in Molecular Biology, Vol. Suppl. 27. F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman. and J. A. Smith. eds. Wiley Press. New York. p. 13.14.1.
14. fyn kinase with the dynein light chain. Tctex-1, and colocalization during cytokinesis. J. Immunol. 161:1728.
15. Lu, X., R. C. Axtell, J. F. Collawn, A. Gibson, L. B. Justement, and C. Raman. 2002. AP2 adaptor complex-dependent internalization of CD5: Differential regulation in T and B cells. J. Immunol. 168:5612.
16. Yusa, S., and K. S. Campbell. 2003. Src homology 2-containing protein tyrosine phosphatase-2 (SHP-2) can play a direct role in the inhibitory function of killer cell Ig-like receptors in human NK cells. J. Immunol. 170:4539.
17. Miellman, I. 1996. Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12:575.
18. Kirchhausen, T. 1999. Adaptors for clathrin-mediated traffic. Annu. Rev. Cell Dev. Biol. 15.705.
19. Ohno, H., M. C. Fournier, G. Poy, and J. S. Bonifacino. 1996. Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chains. J. Biol. Chem. 271:29009.
20. Boll, W., H. Ohno, Z. Songyang, I. Rapoport, L. C. Cantley, J. S. Bonifacino, and T. Kirchhausen. 1996. Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes. EMB0 J. 15: 5789.
21. Sauter, M. M., A. Pelchen-Matthews, R. Bron, M. Marsh, C. C. LaBranche, P. J. Vance, J. Romano, B. S. Haggarty, T. K. Hart, W. M. Lee, and J. A. Hoxie. 1996. An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. J. Cell Biol. 132:795.
22. Campbell, K. S., and M. Colonna. 1999. DAP12: A key accessory protein for relaying signals by natural killer cell receptor. Int. J. Biochem. Cell Biol. 3:631.
23. Sinclair, N. R. 2000. Immunoreceptor tyrosine-based inhibitory motifs on activating molecules. Crit. Rev. Immunol. 20:89.
24. Fame, M., and E. O. Long. 2002. KIR2DL4 (CD158d), an NK-activating receptor with inhibitory potential. J. Immunol. 168:6208.
25. Xiao, S., D. W. Rose, T. Sasaoka, H. Maegawa, T. R. Burke, Jr., P. P. Roller, S. E. Shoelson, and J. M. Olefsky. 1994. Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J. Biol. Chem. 269:21244.
26. Kharitonenkov, A., J. Schnekenburger, Z. Chen, P. Knyazev, S. Ali, E. Zwick, M. White, and A. Ullrich. 1995. Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction. J. Biol. Chem. 270:29189.
27. Kikuchi, A., S.-i. Yusa, T. L. Catina, and K. S. Campbell. 2003. KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-γ production. J. Immunol. 171:3415