-
1
-
-
0028080028
-
Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy
-
Packer RJ, et al: Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy. J Neurosurg 1994;81:690-698.
-
(1994)
J Neurosurg
, vol.81
, pp. 690-698
-
-
Packer, R.J.1
-
3
-
-
0032940605
-
Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors
-
Biegel JA, et al: Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Res 1999;59:74-79.
-
(1999)
Cancer Res
, vol.59
, pp. 74-79
-
-
Biegel, J.A.1
-
4
-
-
0028568009
-
Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
-
Segal RA, et al: Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci USA 1994;91:12867-12871.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12867-12871
-
-
Segal, R.A.1
-
5
-
-
0033083048
-
Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas
-
Kim JY, et al: Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas. Cancer Res 1999;59:711-719.
-
(1999)
Cancer Res
, vol.59
, pp. 711-719
-
-
Kim, J.Y.1
-
6
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy SL, et al: Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 2002;415:436-442.
-
(2002)
Nature
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
-
7
-
-
0030741967
-
Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma
-
Gilbertson RJ, et al: Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res 1997;57:3272-3280.
-
(1997)
Cancer Res
, vol.57
, pp. 3272-3280
-
-
Gilbertson, R.J.1
-
8
-
-
0033994659
-
TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors
-
Grotzer MA, et al: TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors. J Clin Oncol 2000;18:1027-1035.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1027-1035
-
-
Grotzer, M.A.1
-
9
-
-
0034890563
-
MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma
-
Grotzer MA, et al: MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma. Clin Cancer Res 2001;7:2425-2433.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2425-2433
-
-
Grotzer, M.A.1
-
10
-
-
0034330931
-
Efficacy of STI571, an abl tyrosine kinase inhibitor, in conjunction with other antileukemic agents against bcr-abl-positive cells
-
Thiesing JT, et al: Efficacy of STI571, an abl tyrosine kinase inhibitor, in conjunction with other antileukemic agents against bcr-abl-positive cells. Blood 2000;96:3195-3199.
-
(2000)
Blood
, vol.96
, pp. 3195-3199
-
-
Thiesing, J.T.1
-
11
-
-
1642494546
-
Marked regression of a metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec)
-
in press
-
McLaughlin M, et al: Marked regression of a metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec). J Pediatr Hematol Oncol, in press.
-
J Pediatr Hematol Oncol
-
-
McLaughlin, M.1
-
12
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, et al: Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272:1668-1671.
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
-
13
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, et al: Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996;85:841-851.
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
-
14
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo V, et al: Biochemical evidence that patched is the Hedgehog receptor. Nature 1996;384:176-179.
-
(1996)
Nature
, vol.384
, pp. 176-179
-
-
Marigo, V.1
-
15
-
-
0032959871
-
Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
-
Wechsler-Reya RJ, Scott MP: Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 1999;22:103-114.
-
(1999)
Neuron
, vol.22
, pp. 103-114
-
-
Wechsler-Reya, R.J.1
Scott, M.P.2
-
16
-
-
0030913169
-
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched
-
Pietsch T, et al: Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 1997;57:2085-2088.
-
(1997)
Cancer Res
, vol.57
, pp. 2085-2088
-
-
Pietsch, T.1
-
17
-
-
0031036694
-
Sporadic medulloblastomas contain PTCH mutations
-
Raffel C, et al: Sporadic medulloblastomas contain PTCH mutations. Cancer Res 1997;57:842-845.
-
(1997)
Cancer Res
, vol.57
, pp. 842-845
-
-
Raffel, C.1
-
18
-
-
0034221629
-
Identification of PATCHED mutations in medulloblastomas by direct sequencing
-
Dong J, et al: Identification of PATCHED mutations in medulloblastomas by direct sequencing. Hum Mutat 2000;16:89-90.
-
(2000)
Hum Mutat
, vol.16
, pp. 89-90
-
-
Dong, J.1
-
19
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, et al: Mutations in SUFU predispose to medulloblastoma. Nat Genet 2002;31:306-310.
-
(2002)
Nat Genet
, vol.31
, pp. 306-310
-
-
Taylor, M.D.1
-
20
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton SR, et al: The molecular basis of Turcot's syndrome. N Engl J Med 1995;332:839-847.
-
(1995)
N Engl J Med
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
-
21
-
-
0033883092
-
APC mutations in sporadic medulloblastomas
-
Huang H, et al: APC mutations in sporadic medulloblastomas. Am J Pathol 2000;156:433-437.
-
(2000)
Am J Pathol
, vol.156
, pp. 433-437
-
-
Huang, H.1
-
22
-
-
0035427076
-
Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors
-
Koch A, et al: Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors. Int J Cancer 2001;93:445-449.
-
(2001)
Int J Cancer
, vol.93
, pp. 445-449
-
-
Koch, A.1
-
23
-
-
0037056236
-
Role of Wnt pathway in medulloblastoma oncogenesis
-
Yokota N, et al: Role of Wnt pathway in medulloblastoma oncogenesis. Int J Cancer 2002;101:198-201.
-
(2002)
Int J Cancer
, vol.101
, pp. 198-201
-
-
Yokota, N.1
-
24
-
-
0032030894
-
Sporadic medulloblastomas contain oncogenic beta-catenin mutations
-
Zurawel RH, et al: Sporadic medulloblastomas contain oncogenic beta-catenin mutations. Cancer Res 1998;58:896-899.
-
(1998)
Cancer Res
, vol.58
, pp. 896-899
-
-
Zurawel, R.H.1
-
25
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale J, et al: Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000;406:1005-1009.
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
-
26
-
-
0037200078
-
Medulloblastoma growth inhibition by hedgehog pathway blockade
-
Berman DM, et al: Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 2002;297:1559-1561.
-
(2002)
Science
, vol.297
, pp. 1559-1561
-
-
Berman, D.M.1
-
27
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert J, et al: A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol 2002;2:8.
-
(2002)
BMC Dev Biol
, vol.2
, pp. 8
-
-
Willert, J.1
-
28
-
-
0033942317
-
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
-
Lawinger P, et al: The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat Med 2000;6:826-831.
-
(2000)
Nat Med
, vol.6
, pp. 826-831
-
-
Lawinger, P.1
-
29
-
-
0035899347
-
Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas - Implications for tumor biology and potential clinical utility
-
Fruhwald MC, et al: Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas - Implications for tumor biology and potential clinical utility. Oncogene 2001;20:5033-5042.
-
(2001)
Oncogene
, vol.20
, pp. 5033-5042
-
-
Fruhwald, M.C.1
-
30
-
-
0037108984
-
Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development
-
Lusher ME, et al: Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development. Cancer Res 2002;62:5906-5911.
-
(2002)
Cancer Res
, vol.62
, pp. 5906-5911
-
-
Lusher, M.E.1
-
31
-
-
0036139396
-
Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma
-
Zuzak TJ, et al: Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma. Eur J Cancer 2002;38:83-91.
-
(2002)
Eur J Cancer
, vol.38
, pp. 83-91
-
-
Zuzak, T.J.1
-
32
-
-
0036644901
-
Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma
-
Rood BR, et al: Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma. Cancer Res 2002;62:3794-3797.
-
(2002)
Cancer Res
, vol.62
, pp. 3794-3797
-
-
Rood, B.R.1
-
33
-
-
0029040938
-
Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells
-
Segal RA, Pomeroy SL, Stiles CD: Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. J Neurosci 1995;15:4970-4981.
-
(1995)
J Neurosci
, vol.15
, pp. 4970-4981
-
-
Segal, R.A.1
Pomeroy, S.L.2
Stiles, C.D.3
-
34
-
-
0034794796
-
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease
-
MacDonald TJ, et al: Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nat Genet 2001;29:143-152.
-
(2001)
Nat Genet
, vol.29
, pp. 143-152
-
-
MacDonald, T.J.1
-
35
-
-
0035445646
-
Clinical and molecular stratification of disease risk in medulloblastoma
-
Gilbertson R, et al: Clinical and molecular stratification of disease risk in medulloblastoma. Br J Cancer 2001;85:705-712.
-
(2001)
Br J Cancer
, vol.85
, pp. 705-712
-
-
Gilbertson, R.1
-
36
-
-
0037224320
-
ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma
-
Hernan R, et al: ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res 2003;63:140-148.
-
(2003)
Cancer Res
, vol.63
, pp. 140-148
-
-
Hernan, R.1
-
37
-
-
0029912643
-
Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene
-
Ambartsumian NS, et al: Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene. Oncogene 1996;13:1621-1630.
-
(1996)
Oncogene
, vol.13
, pp. 1621-1630
-
-
Ambartsumian, N.S.1
-
38
-
-
0029860590
-
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours
-
Davies MP, et al: Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. Oncogene 1996;13:1631-1637.
-
(1996)
Oncogene
, vol.13
, pp. 1631-1637
-
-
Davies, M.P.1
-
39
-
-
0036278440
-
Insulin-like growth factor I receptor activity in human medulloblastomas
-
Del Valle L, et al: Insulin-like growth factor I receptor activity in human medulloblastomas. Clin Cancer Res 2002;8:1822-1830.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1822-1830
-
-
Del Valle, L.1
-
40
-
-
0036132648
-
Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas
-
Eberhart CG, et al: Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas. Brain Pathol 2002;12:36-44.
-
(2002)
Brain Pathol
, vol.12
, pp. 36-44
-
-
Eberhart, C.G.1
-
41
-
-
0033801873
-
c-myc expression in medulloblastoma and its prognostic value
-
Herms J, et al: c-myc expression in medulloblastoma and its prognostic value. Int J Cancer 2000;89:395-402.
-
(2000)
Int J Cancer
, vol.89
, pp. 395-402
-
-
Herms, J.1
|