Microangiopathies and malignant vascular injury in the kidney

Current Diagnostic Pathology

Volumn 10, Issue 1, 2004, Pages 36-51

  Bellamy, C O C ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

Haemolytic uraemic syndrome; Kidney; Pathology; Thrombotic microangiopathy; Thrombotic thrombocytopaenic purpura

Indexed keywords

BLOOD VESSEL INJURY; CONFERENCE PAPER; CYTODIAGNOSIS; DIFFERENTIAL DIAGNOSIS; DISSEMINATED INTRAVASCULAR CLOTTING; GLOMERULOPATHY; HEMOLYTIC UREMIC SYNDROME; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; MALIGNANT VASCULAR INJURY; MICROANGIOPATHY; PREECLAMPSIA; RENOVASCULAR DISEASE; REVIEW; THROMBOTIC THROMBOCYTOPENIC PURPURA; VASCULITIS;

EID: 1642471823     PISSN: 09686053     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cdip.2003.09.005     Document Type: Conference Paper

References (106)

1. Van Hove JL, Damme-Lombaerts R, Grunewald S, et al. Cobalamin disorder Cbl-C presenting with late-onset thrombotic microangiopathy. Am J Med Genet 2002;111:195-201.
2. Moschcowitz E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Proc N Y Pathol Soc 1924;24:21.
3. Amorosi EL, Ultmann JE. Thromobotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine 1966;45:139-59.
4. Moake JL. Thrombotic microangiopathies. N Engl J Med 2002;347:589-600.
5. Tsai HM. Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura. J Am Soc Nephrol 2003;14:1072-81.
6. Gasser VC, Gautier E, Steck A, Seibenman EE, Oeschlin R. Hämolytisch-urämische Syndrome: bilaterale nierenindennekrosen bei akuten erworbenen hämolytischen Anämien [in German]. Schweiz Med Wochenschr 1955;85:905-9.
7. Koster F, Levin J, Walker L, Tung KS, Gilman RH, Rahaman MM, et al. Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes. N Engl J Med 1978;298:927-33.
8. Symmers WStC. Thrombotic microangiopathic haemolytic anaemia (thrombotic microangiopathy). BMJ 1952;2:897-903.
9. Royer P, Habib R, Mathieu H. La microangiopathie thrombotique du rein chez l'enfant [in French]. Ann Pediatr (Paris) 1960;36:572-87.
10. Richardson SE, Karmali MA, Becker LE, Smith CR. The histopathology of the hemolytic uremic syndrome associated with verocytotoxin-producing Escherichia coli infections. Hum Pathol 1988;19:1102-8.
11. Orbison JL. Morphology of thrombotic thrombocytopenic purpura with demonstration of aneurysms. Am J Pathol 1952;28:129.
12. Asada Y, Sumiyoshi A, Hayashi T, Suzumiya J, Kaketani K. Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen. Thromb Res 1985;38:469-79.
13. Katoh M, Shigematsu H. Renal involvement of thrombotic thrombocytopenic purpura: special reference to the glomerutoid structures. Pathol Int 1999;49:638-42.
14. Harkness DR, Byrnes JJ, Lian EC, Williams WD, Hensley GT. Hazard of platelet transfusion in thrombotic thrombocytopenic purpura. J Am Med Assoc 1981;246:1931-3.
15. Clement R, Bernard J, Papaioannou A, Mathé G, Habib R, Designolle M. Purpura thrombotique thrombocytopénique (Maladie de Moschcovitz) chez une enfant de 10 mois [in French]. Presse Med 1957;94:2144-6.
16. Moghal NE, Ferreira MA, Howie AJ, Milford DV, Raafat E, Taylor CM. The late histologic findings in diarrhea-associated hemolytic uremic syndrome. J Pediatr 1998;133:220-3.
17. Inward CD, Howie AJ, Fitzpatrick MM, Rafaat F, Milford DV, Taylor CM. Renal histopathology in fatal cases of diarrhoea-associated haemolytic uraemic syndrome. British Association for Paediatric Nephrology. Pediatr Nephrol 1997;11:556-9.
18. Habib R, Levy M, Gagnadoux MF, Broyer M. Prognosis of the hemolytic uremic syndrome in children. Adv Nephrol 1982;11:99-128.
19. Taylor CM, Howie AJ, Williams JM. No common final pathogenetic pathway in haemolytic uraemic syndromes. Nephrol Dial Transplant 1999;14:1100-2.
20. Gagnadoux MF, Habib R, Gubler MC, Bacri JL, Broyer M. Long-term (15-25 years) outcome of childhood hemolytic-uremic syndrome. Clin Nephrol 1996;46:39-41.
21. Caletti MG, Gallo G, Gianantonio CA. Development of focal segmental sclerosis and hyalinosis in hemolytic uremic syndrome. Pediatr Nephrol 1996;10:687-92.
22. Tostivint I, Mougenot B, Flahault A, Vigneau C, Costa MA, Haymann JP, et al. Adult haemolytic and uraemic syndrome: causes and prognostic factors in the last decade. Nephrol Dial Transplant 2002;17:1228-34.
23. Laffay DL, Tubbs RR, Valenzuela R, Hall PM, McCormack LJ. Chronic glomerular microangiopathy and metastatic carcinoma. Hum Pathol 1979;10:433-8.
24. Habib R. Pathology of the hemolytic uremic syndrome. In: Kaplan BS, Trompeter RS, Moake JL, editors. Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. New York: Marcel Dekker; 1992. p. 315-53.
25. Morel-Maroger L, Kanfer A, Solez K, Sraer JD, Richet G. Prognostic importance of vascular lesions in acute renal failure with microangiopathic hemolytic anemia (hemolytic-uremic syndrome): clinicopathotogic study in 20 adults. Kidney Int 1979;15:548-58.
26. Trostle DC, Bedetti CD, Steen VD, Al Sabbagh MR, Zee B, Medsger Jr. TA. Renal vascular histology and morphometry in systemic sclerosis. A case-control autopsy study. Arthritis Rheum 1988;31:393-400.
27. Fleming S. Malignant hypertension. J Pathol 2000;192:135-9.
28. Cohen JA, Brecher ME, Bandarenko N. Cellular source of serum lactate dehydrogenase elevation in patients with thrombotic thrombocytopenic purpura. J Clin Apheresis 1998;13:16-9.
29. Grabowski EF. The hemolytic-uremic syndrome-toxin, thrombin, and thrombosis. N Engl J Med 2002;346:58-61.
30. Repetto HA. Epidemic hemolytic-uremic syndrome in children. Kidney Int 1997;52:1708-19.
31. Chandler WL, Jelacic S, Boster DR, et al. Prothrombotic coagulation abnormalities preceding the hemolytic-uremic syndrome. N Engl J Med 2002;346:23-32.
32. Koster FT, Boonpucknavig V, Sujaho S, Gilman RH, Rahaman MM. Renal histopathology in the hemolytic-uremic syndrome following shigellosis. Clin Nephrol 1984;21:126-33.
33. Tsai HM, Chandler WL, Sarode R, Hoffman R, Jelacic S, Habeeb RL, et al. Von willebrand factor and von willebrand factor-cleaving metalloprotease activity in Escherichia coli O157: h7-associated hemolytic uremic syndrome. Pediatr res 2001;49:653-9.
34. Ruggenenti P, Noris M, Remuzzi G. Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Kidney Int 2001;60:831-46.
35. Carter AO, Borczyk AA, Carlson JA, Harvey B, Hockin JC, Karmali MA, et al. A severe outbreak of Escherichia coli O157: H7: associated hemorrhagic colitis in a nursing home. N Engl J Med 1987;317:1496-500.
36. Dundas S, Murphy J, Soutar RL, Jones GA, Hutchinson SJ, Todd WT. Effectiveness of therapeutic plasma exchange in the 1996 Lanarkshire Escherichia coli O157: h7 outbreak. Lancet 1999;354:1327-30.
37. Fitzpatrick MM, Shah V, Trompeter RS, Dillon MJ, Barratt TM. Long term renal outcome of childhood haemolytic uraemic syndrome. BMJ 1991;303:489-92.
38. Furlan M, Robles R, Galbusera M, et al. Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998;339:1578-84.
39. Tsai HM, Rice L, Sarode R, Chow TW, Moake JL. Antibody inhibitors to von Willebrand factor metalloproteinase and increased binding of von Willebrand factor to platelets in ticlopidine-associated thrombotic thrombocytopenic purpura. Ann Intern Med 2000;132:794-9.
40. Bennett CL, Connors JM, Carwile JM, et al. Thrombotic thrombocytopenic purpura associated with clopidogrel. N Engl J Med 2000;342:1773-7.
41. Taylor CM. Complement factor H and the haemolytic uraemic syndrome. Lancet 2001;358:1200-2.
42. Muller T, Sikora P, Offner G, Hoyer PF, Brodehl J. Recurrence of renal disease after kidney transplantation in children: 24 years of experience in a single center. Clin Nephrol 1998;49:82-90.
43. Kaplan BS, Leonard MB. Autosomal dominant hemolytic uremic syndrome: variable phenotypes and transplant results. Pediatr Nephrol 2000;14:464-8.
44. Zipfel PF. Hemolytic uremic syndrome: how do factor H mutants mediate endothetial damage? Trends Immunol 2001;22:345-8.
45. Ohati M, Shalev H, Schlesinger M, Katz Y, Kachko L, Carmi R, et al. Hypocomplementemic autosomal recessive hemolytic uremic syndrome with decreased factor H. Pediatr Nephrol 1998;12:619-24.
46. Warwicker P, Donne RL, Goodship JA, Goodship TH, Howie AJ, Kumararatne DS, et al. Familial relapsing haemolytic uraemic syndrome and complement factor H deficiency. Nephrol Dial Transplant 1999;14:1229-33.
47. Kojouri K, Vesely SK, George JN. Quinine-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: frequency, clinical features, and long-term outcomes. Ann Intern Med 2001;135:1047-51.
48. Rabetoy G, Hansen M, Brosnahan G, Hartung L. The lady who had muscle cramps and developed thrombotic microangiopathy. Nephrol Dial Transplant 2000;15:1464-7.
49. McDonald SP, Shanahan EM, Thomas AC, Roxby DJ, Beroukas D, Barbara JA. Quinine-induced hemolytic uremic syndrome. Clin Nephrol 1997;47:397-400.
50. Barr E, Douglas JF, Hill CM. Recurrent acute hypersensitivity to quinine. BMJ 1990;301:323.
51. Pawar R, Jacobs GH, Smith MC. Quinine-associated acute interstitial nephritis. Am J Kidney Dis 1994;24:211-4.
52. Kressel BR, Ryan KP, Duong AT, Berenberg J, Schein PS. Microangiopathic hemolytic anemia, thrombocytopenia, and renal failure in patients treated for adenocarcinoma. Cancer 1981;48:1738-45.
53. Hostetter AL, Tubbs RR, Ziegler T, Gephardt GN, McMahon JT, Schreiber Jr. MJ. Chronic glomerular microangiopathy complicating metastatic carcinoma. Hum Pathol 1987;18:342-8.
54. Tuttle SE, Sharma HM, Bay WH, Hebert LA. Glomerular basement membrane splitting and microaneurysm formation associated with nitrosourea therapy. Am J Nephrol 1985;5:388-94.
55. Keane WF, Crosson JT, Staley NA, Anderson WR, Shapiro FL. Radiation-induced renal disease. A clinicopathologic study. Am J Med 1976;60:127-37.
56. Robbins ME, Bonsib SM. Radiation nephropathy: a review. Scanning Microsc. 1995;9:535-60.
57. Raife TJ, Lentz SR, Atkinson BS, Vesely SK, Hessner MJ. Factor V Leiden: a genetic risk factor for thrombotic microangiopathy in patients with normal von willebrand factor-cleaving protease activity. Blood 2002;99:437-42.
58. Dashe JS, Ramin SM, Cunningham FG. The Long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy. Obstet Gynecol 1998;91:662-8.
59. Hauglustaine D, Vanrenterghem Y, Michielsen OP, Van Damme B. Oestrogen containing oral contraceptives, decreased prostacyclin production, and haemolytic uraemic syndrome. Lancet 1981;1:328-9.
60. Kniaz D, Eisenberg GM, Elrad H, Johnson CA, Valaitis J, Bregman H. Postpartum hemolytic uremic syndrome associated with antiphospholipid antibodies. A case report and review of the literature. Am J Nephrol 1992;12:126-33.
61. Kincaid-Smith P, Fairley KF, Kloss M. Lupus anticoagulant associated with renal thrombotic microangiopathy and pregnancy-related renal failure. Q J Med 1988;68:795-815.
62. Ezra Y, Rose M, Eldor A. Therapy and prevention of thrombotic thrombocytopenic purpura during pregnancy: a clinical study of 16 pregnancies. Am J Hematol 1996;51:1-6.
63. Segonds A, Louradour N, Suc JM, Orfila C. Postpartum hemolytic uremic syndrome: a study of three cases with a review of the literature. Clin Nephrol 1979;12:229-42.
64. Fogo AB. Renal diseases in pregnancy. In: Jennette JC, Olson JL, Schwartz MM, Silva FG, editors. Heptinstall's pathology of the kidney. 5th ed. New York: Lippincott-Raven; 1998. p. 1097-130.
65. Schwimmer J, Nadasdy TA, Spitalnik PF, Kaplan KL, Zand MS. De novo thrombotic microangiopathy in renal transplant recipients: a comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy. Am J Kidney Dis 2003;41:471-9.
66. Ruggenenti P. Post-transplant hemolytic-uremic syndrome. Kidney Int 2002;62:1093-4.
67. Candinas D, Keusch G, Schlumpf R, Burger HR, Weder W, Largiader F. Prognostic factors of hemolytic uremic syndrome in renal allografts. Transplant Proc 1993;25:1041-2.
68. Zarifian A, Meleg-Smith S, O'donovan R, Tesi RJ, Batuman V. Cyclosporine-associated thrombotic microangiopathy in renal allografts. Kidney Int 1999;55:2457-66.
69. Randhawa PS, Tsamandas AC, Magnone M, Jordan M, Shapiro R, Starzl TE, et al. Microvascular changes in renal allografts associated with FK506 (Tacrolimus) therapy. Am J Surg Pathol 1996;20(3):306-12.
70. Neild GH, Reuben R, Hartley RB, Cameron JS. Glomerular thrombi in renal allografts associated with cyclosporin treatment. J Clin Pathol 1985;38:253-8.
71. Taube DH, Neild GH, Williams DG, Cameron JS, Hartley B, Ogg CS, et al. Differentiation between allograft rejection and cyclosporin nephrotoxicity in renal-transplant recipients. Lancet 1985;2:171-4.
72. Hochstetler LA, Flanigan MJ, Lager DJ. Transplant-associated thrombotic microangiopathy: the role of igg administration as initial therapy. Am J Kidney Dis 1994;23:444-50.
73. Beaufils H, de Groc F, Gubler MC, Wechsler B, Le Hoang P, Baumelou A, et al. Hemolytic uremic syndrome in patients with Behcet's disease treated with cyclosporin A: report of 2 cases. Clin Nephrol 1990;34:157-62.
74. Abramowicz D, Pradier O, Marchant A, Florquin S, De Pauw L, Vereerstraeten P, et al. Induction of thromboses within renal grafts by high-dose prophylactic OKT3. Lancet 1992;339:777-8.
75. Waiser J, Budde K, Rudolph B, Ortner MA, Neumayer HH. De novo hemolytic uremic syndrome postrenal transplant after cytomegalovirus infection. Am J Kidney Dis 1999;34:556-9.
76. Murer L, Zacchello G, Bianchi D, et al. Thrombotic microangiopathy associated with parvovirus B 19 infection after renal transplantation. J Am Soc Nephrol 2000;11:1132-7.
77. Baid S, Pascual M, Williams Jr. WW, et al. Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients. J Am Soc Nephrol 1999;10:146-53.
78. Ducloux D, Pellet E, Fournier V, Rebibou JM, Bresson-Vautrin C, Racadot E, et al. Prevalence and clinical significance of antiphospholipid antibodies in renal transplant recipients. Transplantation 1999;67(1):90-3.
79. Nzerue CM, Hewan-Lowe K, Pierangeli S, Harris EN. 'Black swan in the kidney': renal involvement in the antiphospholipid antibody syndrome. Kidney Int 2002;62:733-44.
80. Leaker B, McGregor A, Griffiths M, Snaith M, Neild GH, Isenberg D. Insidious loss of renal function in patients with anticardiolipin antibodies and absence of overt nephritis. Br J Rheumatol 1991;30:422-5.
81. Daugas E, Nochy D, Huong du LT, et al. Antiphospholipid syndrome nephropathy in systemic lupus erythematosus. J Am Soc Nephrol 2002;13:42-52.
82. Bridoux F, Vrtovsnik F, Noel C, Saunier P, Mougenot B, Lemaitre V, et al. Renal thrombotic microangiopathy in systemic lupus erythematosus: clinical correlations and long-term renal survival. Nephrol Dial Transplant 1998;13:298-304.
83. D'Agati V, Kunis C, Williams G, Appel GB. Anti-cardiolipin antibody and renal disease: a report three cases. J Am Soc Nephrol 1990;1:777-84.
84. Nochy D, Daugas E, Droz D, Beaufils H, Grunfeld JP, Piette JC, et al. The intrarenal vascular lesions associated with primary antiphospholipid syndrome. J Am Soc Nephrol 1999;10:507-18.
85. Asherson RA, Cervera R, Piette JC, et al. Catastrophic antiphospholipid syndrome. Clinical and laboratory features of 50 patients. Medicine (Baltimore) 1998;77:195-207.
86. Banfi G, Bertani T, Boeri V, et al. Renal vascular lesions as a marker of poor prognosis in patients with lupus nephritis. Gruppo Italiano per lo Studio della Nefrite Lupica (GISNEL). Am J Kidney Dis 1991;18:240-8.
87. Descombes E, Droz D, Drouet L, Grunfeld JP, Lesavre P. Renal vascular lesions in lupus nephritis. Medicine (Baltimore) 1997;76:355-68.
88. Klein PJ, Bulla M, Newman RA, et al. Thomsen-Friedenreich antigen in haemolytic-uraemic syndrome. Lancet 1977;2:1024-5.
89. Sherbotie JR, van HV, Axton R, Williamson K, Finn LS, Kaplan BS. Hemolytic uremic syndrome associated with Denys-Drash syndrome. Pediatr Nephrol 2000;14:1092-7.
90. Kincaid-Smith P. The renal lesion of preeclampsia revisited. Am J Kidney Dis 1991;17:144-8.
91. Spargo BH, McCartney CP, Winemiller R. Glomerular capillary endothetiosis in toxemia of pregnancy. Arch Pathol 1959;68:593-9.
92. Gaber LW, Spargo BH, Lindheimer MD. Renal pathology in pre-eclampsia. Baillieres Clin Obstet Gynaecol 1994;8:443-68.
93. Nishimoto K, Shiiki H, Nishino T, et al. Glomerular hypertrophy in preeclamptic patients with focal segmental glomerulosclerosis. A morphometric analysis. Clin Nephrol 1999;51:209-19.
94. Nochy D, Birembaut P, Hinglais N, Freund M, Idatte JM, Jacquot C, et al. Renal lesions in the hypertensive syndromes of pregnancy: immunomorphological and ultrastructural studies in 114 cases. Clin Nephrol 1980;13:155-62.
95. Maryniak RK, First MR, Weiss MA. Transplant glomerulopathy: evolution of morphologically distinct changes. Kidney Int 1985;27:799-806.
96. Fukatsu A, Tamai H, Nishikawa K, Matsukawa W, Yoshida F, Matsuo S, et al. The kidney disease of Crow-Fukase (POEMS) syndrome: a clinico-pathological study of four cases. Clin Nephrol 1991;36:76-82.
97. Robboy SJ, Major MC, Colman RW, Minna JD. Pathology of disseminated intravascular coagulation (DIC). Analysis of 26 cases. Hum Pathol 1972;3:327-43.
98. Umlas J. Glomeruloid structures in thrombohemolytic thrombocytopenic purpura, glomerulonephritis, and disseminated intravascular coagulation. Hum Pathol 1972;3:437-41.
99. Appel GB, Pirani CL, D'Agati V. Renal vascular complications of systemic lupus erythematosus. J Am Soc Nephrol 1994;4:1499-515.
100. Baldwin DS, Gluck MC, Lowenstein J, Gallo GR. Lupus nephritis. Clinical course as related to morphologic forms and their transitions. Am J Med 1977;62:12-30.
101. Grishman E, Venkataseshan VS. Vascular lesions in lupus nephritis. Mod Pathol 1988;1:235-41.
102. Morozumi K, Thiel G, Albert FW, Banfi G, Gudat F, Mihatsch MJ. Studies on morphological outcome of cyclosporine-associated arteriotopathy after discontinuation of cyclosporine in renal allografts. Clin Nephrol 1992;38:1-8.
103. Mihatsch MJ, Thiel G, Basler V, et al. Morphological patterns in cyclosporine-treated renal transplant recipients. Transplant Proc 1985;17:101-16.
104. Strom EH, Thiel G, Mihatsch MJ. Prevalence of cyclosporine-associated arteriolopathy in renal transplant biopsies from 1981 to 1992. Transplant Proc 1994;26:2585-7.
105. Rosenmann E, Pollak VE, Pirani CL. Renal vein thrombosis in the adult: a clinical and pathologic study based on renal biopsies. Medicine (Baltimore) 1968;47:269-335.
106. Pollak VE, Weiss MA. Renal vein thrombosis. In: Tisher CC, Brenner BM, editors. Renal Pathology with Clinical and Functional Correlations. 2nd ed. Philadelphia: J.B. Lippincott Company; 1994. p. 1185-200.