Renal histopathology in fatal cases of diarrhoea-associated haemolytic uraemic syndrome

Pediatric Nephrology

Volumn 11, Issue 5, 1997, Pages 556-559

  Inward, Carol D ^a   Howie, Alec J ^b   Fitzpatrick, Margaret M ^c   Rafaat, Faro ^a   Milford, David V ^a   Taylor, C Mark ^a  

^a BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Arteriolar thromboses; Glomerular thrombosis; Haemolytic uraemic syndrome; Neutrophils

Indexed keywords

CD15 ANTIGEN; LEUKOCYTE ELASTASE; VEROTOXIN;

ARTICLE; AUTOPSY; CHILD; CLINICAL ARTICLE; DIARRHEA; DISEASE DURATION; ESCHERICHIA COLI; FATALITY; GLOMERULUS; HEMOLYTIC UREMIC SYNDROME; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; INFANT; KIDNEY; KIDNEY CORTEX; KIDNEY INFARCTION; KIDNEY ISCHEMIA; NEUTROPHIL; NEUTROPHILIA; PATHOGENESIS; PRIORITY JOURNAL; STAINING; THROMBOSIS; UNITED KINGDOM;

CHILD; CHILD, PRESCHOOL; DIARRHEA; ESCHERICHIA COLI INFECTIONS; HEMOLYTIC-UREMIC SYNDROME; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; KIDNEY; LEUKOCYTE COUNT; NEUTROPHILS;

EID: 0030766460     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004670050337     Document Type: Article

References (18)

1. Habib R, Levy M, Gagnadoux MF, Broyer M (1982) Prognosis of the hemolytic uremic syndrome in children. Adv Nephrol 11.99-128
2. Walters MD, Matthei I, Kay R, Dillon MJ, Barratt TM (1989) The polymorphonuclear leucocyte count in childhood haemolytic uraemic syndrome. Pediatr Nephrol 3. 130-134
3. De Chadarevian J-P, Kaplan BS (1978) The hemolytic uremic syndrome of childhood. Perspect Pediatr Pathol 4:465-502
4. Coad NAG, Marshall T, Rowe B, Taylor CM (1991) Changes in the postenteropathic form of the haemolytic uremic syndrome in children. Clin Nephrol 35. 10-16
5. Jones EL, Gregory J (1989) Immunoperoxidase methods. In Catty D (ed) Antibodies: a practical approach. vol 2. IRL, Oxford, pp 155-177
6. Karmali MA, Petric M, Lim C, Fleming PC, Arbus GS, Lior H (1985) The association between idiopathic hemolytic uremic syndrome and infection by Verotoxin-producing Escherichia coli. J Infect Dis 151.775-781
7. Vitsky BH, Suzuki Y, Strauss L, Churg J (1969) The hemolytic uremic syndrome: a study of renal pathological alterations. Am J Pathol 57:627-639
8. Argyle JC, Hogg RJ, Pysher TJ, Silva FG, Siegler RL (1990) A clinicopathological study of 24 children with hemolytic uremic syndrome. Pediatr Nephrol 4:52-58
9. Richardson SE, Karmali MA, Becker LE, Smith CR (1988) The histopathology of the hemolytic uremic syndrome associated with verocytotoxin-producing Escherichia coli infections. Hum Pathol 19:1102-1108
10. Renaud C, Niaudet P, Gagnadoux MF, Broyer M, Habib R (1995) Haemolytic uraemic syndrome: prognostic factors in children over 3 years of age. Pediatr Nephrol 9:24-29
11. Obrig TG, Del Vecchio PJ, Karmali MA, Petric M, Moran TP, Judge TK (1987) Pathogenesis of haemolytic uraemic syndrome. Lancet II.687 (1987)
12. Barley-Maloney L, Obrig T, Daniel T (1990) Human renal microvascular endothelial cells (HRMEC) are targets for hemolytic uremic syndrome (HUS)-associated verotoxin (VT). J Am S Nephrol 1:515
13. Pavia AT, Nichols CR, Gren DP, Tauxe RV, Mottice S, Greene KD, Wells JG, Siegler RL, Brewer ED, Hannon D, Blake PA (1990) Hemolytic-uremic syndrome during an outbreak of Escherichia coh 0157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observations. J Pediatr 116:544-551
14. Milford DV, Staten J, MacGreggor I, Dawes J, Taylor CM, Hill FG (1991) Prognostic markers in diarrhoea-associated haemolyticuraemic syndrome: initial neutrophil count, human neutrophil elastase and Von Willebrand factor antigen. Nephrol Dial Transplant 6:232-237
15. Fitzpatrick MM, Shah V, Trompeter RS, Dillon MJ, Barratt TM (1992) Interleukin-8 and polymorphoneutrophil leucocyte activation in hemolytic uremic syndrome of childhood. Kidney Int 42:951-956
16. Inward CD, Pall AA, Adu D, Milford DV, Taylor CM (1995) Soluble circulating cell adhesion molecules in haemolytic uraemic syndrome. Pediatr Nephrol 9:574-578
17. Koster F, Levin J, Walker L, Tung KS, Oilman RH, Rahaman MM, Majid MA, Islam S, Williams RC (1978) Hemolytic uremic syndrome after shigellosis. Relation to endotoxaemia and circulating immune complexes. N Engl J Med 298:927-933
18. Vedaranayan VV, Kaplan BS, Fong JSC (1987) Neutrophil function in modified generalized Schwartzman reaction. A model resembling hemolytic uremic syndrome. Pediatr Res 21:22-26