Expression of a cytokeratin 18 neo-epitope is a specific marker for trophoblast apoptosis in human placenta

Placenta

Volumn 22, Issue 1, 2001, Pages 44-48

  Kadyrov, M ^a   Kaufmann, P ^a   Huppertz, B ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; CASPASE; CASPASE 3; CYTOKERATIN 18; CYTOKERATIN 7; ENDONUCLEASE; EPITOPE; PROTEIN ANTIBODY;

ANTIBODY LABELING; ANTIGEN RECOGNITION; APOPTOSIS; ARTICLE; ARTIFACT; CELL SPECIFICITY; CONTROLLED STUDY; DNA CLEAVAGE; ENZYME ACTIVATION; EPITHELIUM CELL; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; IMMUNITY; IMMUNOREACTIVITY; NICK END LABELING; PLACENTA; PLACENTA VILLUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STAINING; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

EID: 0035146545     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2000.0616     Document Type: Article

References (19)

1. Antibody reaction patterns in first trimester placenta: Implications for trophoblast isolation and purity screening
2. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
3. Caspase enzyme activity is not essential for apoptosis during thymocyte development
4. Cell culture models of human trophoblast-primary culture of trophoblast-a workshop report
5. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
6. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
7. Studies of mesenchymal cells from 1st trimester human placenta: Expression of cytokeratin outside the trophoblast lineage
8. Trophoblast apoptosis and placental development-a workshop report
9. The apoptosis cascade-morphological and immunohistochemical methods for its visualization
10. Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta
11. Apoptosis cascade progresses during turnover of human trophoblast: Analysis of villous cytotrophoblast and syncytial fragments in vitro
12. Apoptosis in human chorionic villi and decidua during normal embryonic development and spontaneous abortion in the first trimester
13. TUNEL apoptotic cell detection in tissue sections: Critical evaluation and improvement
14. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
15. Proliferation, differentiation and apoptosis in villous trophoblast at 13-41 weeks of gestation (including observations or annulate lamellae and nuclear pore complexes)
16. Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: A unique model of apoptosis within a syncytium
17. Review: Nuclear events in apoptosis
18. Apoptotic cells in the human endometrium and placental villi: Pitfalls in applying the TUNEL method