Reduced expression and aberrant localization of p120catenin in human squamous cell carcinoma of the skin

Journal of Dermatological Science

Volumn 34, Issue 2, 2004, Pages 99-108

  Ishizaki, Yasuko ^a   Omori, Yasufumi ^a   Momiyama, Megumi ^a   Nishikawa, Yuji ^a   Tokairin, Takuo ^a   Manabe, Motomu ^a   Enomoto, Katsuhiko ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

E cadherin; Expression pattern; p120catenin; Skin tumor; Squamous cell carcinoma

Indexed keywords

CATENIN; PROTEIN P120; UVOMORULIN;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER GROWTH; CANCER LOCALIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPIDERMIS CELL; FEMALE; GENE LOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEBORRHEIC KERATOSIS; SKIN CARCINOMA; SKIN CULTURE; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CELL ADHESION MOLECULES; CELL LINE, TUMOR; DOWN-REGULATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINOCYTES; PHOSPHOPROTEINS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN NEOPLASMS;

EID: 1642387751     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2003.12.001     Document Type: Article

References (27)

1. Reynolds A.B., Herbert L., Cleveland J.L., Berg S.T., Gaut J.R. p120, a novel substrate of protein tyrosine kinase receptors and of p60v-src, is related to cadherin-binding factors beta-catenin, plakoglobin and armadillo. Oncogene. 7:1992;2439-2445.
2. Daniel J.M., Reynolds A.B. The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin. Mol. Cell Biol. 15:1995;4819-4824.
3. ctn binds to the membrane-proximal region of the E-cadherin cytoplasmic domain and is involved in modulation of adhesion activity. J. Biol. Chem. 274:1999;21409-21415.
4. ctn interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol. Cell Biol. 19:1999;3614-3623.
5. ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression. Proc. Natl. Acad. Sci. U.S.A. 96:1999;7980-7985.
6. Mo Y.Y., Reynolds A.B. Identification of murine p120 isoforms and heterogeneous expression of p120cas isoforms in human tumor cell lines. Cancer Res. 56:1996;2633-2640.
7. Keirsebilck A., Bonne S., Staes K., van Hengel J., Nollet F., Reynolds A., van Roy F. Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms. Genomics. 50:1998;129-146.
8. Aho S., Rothenberger K., Uitto J. Human p120ctn catenin: tissue-specific expression of isoforms and molecular interactions with BP180/type XVII collagen. J. Cell. Biochem. 73:1999;390-399.
9. Montonen O., Aho M., Uitto J., Aho S. Tissue distribution and cell type-specific expression of p120ctn isoforms. J. Histochem. Cytochem. 49:2001;1487-1496.
10. Anastasiadis P.Z., Reynolds A.B. The p120 catenin family: complex roles in adhesion. J. Cell. Sci. 113:2000;1319-1334.
11. ctn from E-cadherin disrupts strong adhesion. J. Cell. Biol. 148:2000;189-202.
12. Ireton R.C., Davis M.A., van Hengel J., Mariner D.J., Barnes K., Thoreson M.A.et al. A novel role for p120 catenin in E-cadherin function. J. Cell. Biol. 159:2002;465-476.
13. ctn acts as an inhibitory regulator of cadherin function in colon carcinoma cells. J. Cell. Biol. 145:1999;551-562.
14. ctn in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity. J. Cell. Sci. 114:2001;503-512.
15. Anastasiadis P.Z., Moon S.Y., Thoreson M.A., Mariner D.J., Crawford H.C., Zheng Y.et al. Inhibition of RhoA by p120 catenin. Nat. Cell Biol. 2:2000;637-644.
16. Noren N.K., Liu B.P., Burridge K., Kreft B. p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J. Cell. Biol. 150:2000;567-580.
17. Anastasiadis P.Z., Reynolds A.B. Regulation of Rho GTPases by p120-catenin. Curr. Opin. Cell. Biol. 13:2001;604-610.
18. Thoreson M.A., Reynolds A.B. Altered expression of the catenin p120 in human cancer: implications for tumor progression. Differentiation. 70:2002;583-589.
19. 2+ concentration. J. Invest. Dermatol. 89:1987;167-171.
20. Kondo S., Aso K. Establishment of a cell line of human skin squamous cell carcinoma in vitro. Br. J. Dermatol. 105:1981;125-132.
21. Hozumi Y., Kondo S., Shimoura T., Aso K. Human squamous cell carcinoma from skin: establishment and characterization of a new cell line (HSC-5). J. Dermatol. 17:1990;143-148.
22. Schoop V.M., Mirancea N., Fusenig N.E. Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J. Invest. Dermatol. 112:1999;343-353.
23. Cozzolino M., Stagni V., Spinardi L., Campioni N., Fiorentini C., Salvati E.et al. p120 Catenin is required for growth factor-dependent cell motility and scattering in epithelial cells. Mol. Biol Cell. 14:2003;1964-1977.
24. Pacquelet A., Lin L., Rorth P. Binding site for p120/delta-catenin is not required for Drosophila E-cadherin function in vivo. J. Cell Biol. 160:2003;313-319.
25. Myster S.H., Cavallo R., Anderson C.T., Fox D.T., Peifer M. Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component. J. Cell Biol. 160:2003;433-449.
26. Aho S., Levansuo L., Montonen O., Kari C., Rodeck U., Uitto J. Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells. J. Cell Sci. 115:2002;1391-1402.
27. Mayerle J., Friess H., Buchler M.W., Schnekenburger J., Weiss F.U., Zimmer K.P.et al. Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer. Gastroenterology. 124:2003;949-960.