p120(ctn) Acts as an inhibitory regulator of cadherin function in colon carcinoma cells

Journal of Cell Biology

Volumn 145, Issue 3, 1999, Pages 551-562

  Aono, Shinya ^a   Nakagawa, Shinichi ^a,c   Reynolds, Albert B ^b   Takeichi, Masatoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Catenin; Colo 205; Colon carcinoma; E cadherin; p120(ctn)

Indexed keywords

CADHERIN; CATENIN; STAUROSPORINE; TRYPSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARCINOMA CELL; CELL ADHESION; CELL FUNCTION; COLON CARCINOMA; ELECTROPHORETIC MOBILITY; GENE REARRANGEMENT; GROWTH INHIBITION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ALKALOIDS; ALPHA CATENIN; BENZOQUINONES; BETA CATENIN; BINDING SITES; CA-15-3 ANTIGEN; CADHERINS; CELL ADHESION MOLECULES; CELL AGGREGATION; CYTOSKELETAL PROTEINS; DNA PRIMERS; DNA, COMPLEMENTARY; ELECTROPHORESIS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENISTEIN; HT29 CELLS; HUMANS; KIDNEY; LACTAMS, MACROCYCLIC; MEMBRANE GLYCOPROTEINS; NAPHTHALENES; PHOSPHOPROTEINS; QUINONES; STAUROSPORINE; TRANS-ACTIVATORS; TRANSFECTION;

EID: 0033519239     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.3.551     Document Type: Article

References (67)

1. Baeckstrom, D., G.C. Hansson, O. Nilsson, C. Johanssoo, S.J. Gendler, and L. Lindholm. 1991. Purification and characterization of a membrane-bound and a secreted mucin-type glycoprotein carrying the carcinoma-associated sialyl-Lea epitope on distinct core proteins. J. Biol. Chem. 266:21537-21547.
2. Balsamo, J., C. Arregui, T. Leung, and J. Lilien. 1998. The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage. J. Cell Biol. 143:523-532.
3. Barth, A.I.M., I.S. Näthke, and W.J. Nelson. 1997. Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9:683-690.
4. Brieher, W.M., A.S. Yap, and B.M. Gumbiner. 1996. Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135: 487-496.
5. Calautti, E., S. Cabodi, P.L. Stein, M. Hatzfeld, N. Kedersha, and G. Paolo Dotto. 1998. Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion. J. Cell Biol. 141:1449-1465.
6. Chantret, I., A. Barbat, E. Dussaulx, M.G. Brattain, and A. Zweibaum. 1988. Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines. Cancer Res. 48:1936-1942.
7. Chen, H., N.E. Paradies, M. Fedor-Chaiken, and R. Brackenbury. 1997. E-cadherin mediates adhesion and suppresses cell motility via distinct mechanisms. J. Cell Sci. 110:345-356.
8. Chitaev, N.A., and S.M. Troyanovsky. 1998. Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation. J. Cell Biol. 142:837-846.
9. cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or α-catenin. Mol. Cell. Biol. 15:4819-4824.
10. Finnemann, S., I. Mitrik, M. Hess, G. Otto, and D. Wedlich. 1997. Uncoupling of XB/U-cadherin-catenin complex formation from its function in cell-cell adhesion. J. Biol. Chem. 272:11856-11862.
11. Fogh, J., and G. Trempe. 1975. New human tumor lines. In Human Tumor Cells In Vitro. J. Fogh, editor. Plenum Press, New York. 115-141.
12. Gaush, C.R., W.L. Hard, and T.F. Smith. 1966. Characterization of an established line of canine kidney cells (MDCK). Proc. Soc. Exp. Biol. Med. 122: 931-935.
13. cas IB in Xenopus embryos affects head differentiation but not axis formation. Dev. Genes Evol. 207:471-481.
14. v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO (Eur. Mol. Biol. Organ.) J. 12:307-314.
15. Hatzfeld, M., and C. Nachtsheim. 1996. Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins. J. Cell Sci. 109:2767-2778.
16. Hazan, R.B., and L. Norton. 1998. The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton. J. Biol. Chem. 273:9078-9084.
17. Heid, H.W., A. Schmidt, R. Zimbelmann, S. Schafer, S. Winter-Simanowski, S. Stumpp, M. Keith, U. Figge, M. Schnolzer, and W.W. Franke. 1994. Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein). Differentiation. 58:113-131.
18. Hirano, S., N. Kimoto, Y. Shimoyama, S. Hirohashi, and M. Takeichi. 1992. Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization. Cell. 70:293-301.
19. Hopp, T.P., K.S. Prickett, V.L. Price, R.T. Libby, C.J. March, D.P. Cerretti, D.L. Urdal, and P.J. Conlon. 1988. A short polypeptide marker sequence useful for recombinant protein identification and purification. Biotechnology. 6:1204-1210.
20. Johnson, K.R., J.E. Lewis, D. Li, J. Wahl, A.P. Soler, K.A. Knudsen, and M.J. Wheelock. 1993. P-and E-cadherin are in separate complexes in cells expressing both cadherins. Exp. Cell Res. 207:252-260.
21. Kanegae, Y., M. Makimura, and I. Saito. 1994. A simple and efficient method for purification of infectious recombinant adenovirus. Jpn. J. Med. Sci. Biol. 47:157-166.
22. Kemperman, H., Y. Wijnands, J. Wesseling, C.M. Niessen, A. Sonnenberg, and E. Roos. 1994. The mucin epiglycanin on TA3/Ha carcinoma cells prevents α6β4-mediated adhesion to laminin and kalinin and E-cadherin-mediated cell-cell interactioa J. Cell Biol. 127:2071-2080.
23. Kinch, M.S., G.J. Clark, C.J. Der, and K. Burridge. 1995. Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. J. Cell Biol. 130:461-471.
24. Kintner, C. 1992. Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell. 69:225-236.
25. Knudsen, K.A., A.P. Soler, K.R. Johnson, and M.J. Wheelock. 1995. Interaction of α-actinin with the cadherin/catenin cell-cell adhesion complex via α-catenin. J. Cell Biol. 130:67-77.
26. Kondo, K., N. Kohno, A. Yokoyama, and K. Hiwada. 1998. Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines. Cancer Res. 58:2014-2019.
27. Lampugnani, M.G., M. Corada, P. Andriopoulou, S. Esser, W. Risau, and E. Dejana. 1997. Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells. J. Cell Sci. 110:2065-2077.
28. Lu, Q., M. Parades, M. Medina, J. Zhou, R. Cavallo, M. Peifer, L. Orecchio, and K.S. Kosik. 1999. δ-Catenin, an adhesive junction-associated protein which promotes cell scattering. J. Cell Biol. 144:519-532.
29. Matsuyoshi, N., M. Hamaguchi, S. Taniguchi, A. Nagafuchi, S. Tsukita, and M. Takeichi. 1992. Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118:703-714.
30. Mertens, C., C. Kuhn, and W.W. Franke. 1996. Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque. J. Cell Biol. 135:1009-1025.
31. cas isoforms in human tumor cell lines. Cancer Res. 56:2633-2640.
32. Moriyoshi, K., L.J. Richards, C. Akazawa, D.D. O'Leary, and S. Nakanishi. 1996. Labeling neural cells using adenoviral gene transfer of membrane-targeted GFP. Neuron. 16:255-260.
33. Nakagawa, S., and M. Takeichi. 1998. Neural crest emigration from the neural tube depends on regulated cadherin expression. Development. 125:2963-2971.
34. Nakagawa, K., S. Sogo, K. Hioki, R. Tokunaga, and S. Taketani. 1998. Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation. Differentiation. 62:249-257.
35. Niwa, H., K. Yamamura, and J. Miyazaki. 1991. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 108:193-200.
36. Oyama, T., Y. Kanai, A. Ochiai, S. Akimoto, T. Oda, K. Yanagihara, A. Nagafuchi, S. Tsukita, S. Shibamoto, F. Ito, et al. 1994. A truncated β-catenin disrupts the interaction between E-cadherin and α-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines. Cancer Res. 54:6282-6287.
37. Ozawa, M., and R. Kemler. 1998a. Altered cell adhesion activity by pervanadate due to the dissociation of α-catenin from the E-cadherin-catenin complex. J. Biol. Chem. 273:6166-6170.
38. Ozawa, M., and R. Kemler. 1998b. The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity. J. Cell Biol. 142:1605-1613.
39. Paffenholz, R., and W.W. Franke. 1997. Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family. Differentiation. 61:293-304.
40. ctn 1A perturbs Xenopus gastrulation. Develop. Biol. 207:350-363.
41. Peifer, M., S. Berg, and A.B. Reynolds. 1994. A repeating amino acid motif shared by proteins with diverse cellular roles. Cell. 76:789-791.
42. Ratcliffe, M.J., L.L. Rubin, and J.M. Staddon. 1997. Dephosphorylation of the cadherin-associated p100/p120 proteins in response to activation of protein kinase C in epithelial cells. J. Biol. Chem. 272:31894-31901.
43. Reynolds, A.B., D.J. Roesel, S.B. Kanner, and J.T. Parsons. 1989. Transformation specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene. Mol. Cell. Biol. 9:629-638.
44. v-src, is related to cadherin-binding factors β-catenin, plakoglobin and armadillo. Oncogene. 7:2439-2445.
45. cas associates with E-cadherin complexes. Mol. Cell. Biol. 14:8333-8342.
46. cas binds classical cadherins and induces an unusual morphological phenotype in NIH3T3 fibroblasts. Exp. Cell Res. 225:328-337.
47. Riehl, R., K. Johnson, R. Bradley, G.B. Grunwald, E. Cornel, A. Lilienbaum, and C.E. Holt. 1996. Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo. Neuron. 17:837-848.
48. Rimm, D.L., E.R. Koslov, P. Kebriaei, C.D. Cianci, and J.S. Morrow. 1995. α1 (E)-Catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc. Natl. Acad. Sci. USA. 92:8813-8817.
49. Rosato, R., J.M. Veltmaat, J. Groffen, and N. Heisterkamp. 1998. Involvement of the tyrosine kinase fer in cell adhesion. Mol. Cell. Biol. 18:5762-5770.
50. Semple, T.U., L.A. Ouinn, L.K. Woods, and G.E. Moore. 1978. Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model. Cancer Res. 38:1345-1355.
51. Serres, M., C. Grangeasse, M. Haftek, Y. Durocher, B. Duclos, and D. Schmitt. 1997. Hyperphosphorylation of β-catenin on serine-threonine residues and loss of cell-cell contacts induced by calyculin A and okadaic acid in human epidermal cells. Exp. Cell Res. 231:163-172.
52. Shibamoto, S., M. Hayakawa, K. Takeuchi, T. Hori, K. Miyazawa, N. Kitamura, K.R. Johnson, M.J. Wheelock, N. Matsuyoshi, M. Takeichi, et al. 1995. Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes. J. Cell Biol. 128:949-957.
53. Shimoyama, Y., S. Hirohashi, S. Hirano, M. Noguchi, Y. Shimosato, M. Takeichi, and O. Abe. 1989. Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res. 49:2128-2133.
54. Shimoyama, Y., A. Nagafuchi, S. Fujita, M. Gotoh, M. Takeichi, S. Tsukita, and S. Hirohashi. 1992. Cadherin dysfunction in a human cancer cell line: possible involvement of loss of α-catenin expression in reduced cell-cell adhesiveness. Cancer Res. 52:5770-5774.
55. Shiozaki, H., H. Oka, M. Inoue, S. Tamura, and M. Monden. 1996. E-cadherin mediated adhesion system in cancer cells. Cancer. 77:1605-1613.
56. Sirotkin, H., H. O'Donnell, R. DasGupta, S. Halford, B. St. Jore, A. Puech, S. Parimoo, B. Morrow, A. Skoultchi, S.M. Weissman, et al. 1997. Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome. Genomics. 41:75-83.
57. Staddon, J.M., C. Smales, C. Schulze, F.S. Esch, and L.L. Rubin. 1995. p120, a p120-related protein (p100), and the cadherin/catenin complex. J. Cell Biol. 130:369-381.
58. Takahashi, I., E. Kobayashi; H. Nakano, C. Murakata, H. Saitoh, K. Suzuki, and T. Tamaoki. 1990. Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C. J. Pharmacol Exp. Ther. 255:1218-1221.
59. Takahashi, K., K. Suzuki, and Y. Tsukatani. 1997. Induction of tyrosine phosphorylation and association of β-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. Oncogene. 15:71-78.
60. Takeichi, M. 1977. Functional correlation between cell adhesive properties and some cell surface proteins. J. Cell Biol. 75:464-474.
61. Takeichi, M. 1988. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development. 102:639-655.
62. Watabe, M., A. Nagafuchi, S. Tsukita, and M. Takeichi. 1994. Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J. Cell Biol. 127:247-256.
63. Watabe-Uchida, M., N. Uchida, Y. Imamura, A. Nagafuchi, K. Fujimoto, T. Uemura, S. Vermeulen, F. van Roy, E.D. Adamson, and M. Takeichi. 1998. α-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells. J. Cell Biol. 142:847-857.
64. Wesseling, J., S.W. van der Valk, and J. Hilkens. 1996. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1. Mol. Biol. Cell 7:565-577.
65. Yamamoto, M., V.P. Bhavanandan, S. Nakamori, and T. Irimura. 1996. A novel monoclonal antibody specific for sialylated MUC1 mucin. Jpn. J. Cancer Res. 87:488-496.
66. Yap, A.S., W.M. Brieher, M. Pruschy, and B.M. Gumbiner. 1997. Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function. Curr. Biol. 7:308-315.
67. ctn. J. Cell Biol. 141:779-789.