메뉴 건너뛰기




Volumn 18, Issue 2, 2004, Pages 214-218

Thiopurine methyltransferase activity in red blood cells of dogs

Author keywords

Drug metabolism; Drug toxicity; Pharmacogenetics

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

EID: 1642305900     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2004)18<214:TMAIRB>2.0.CO;2     Document Type: Article
Times cited : (27)

References (47)
  • 1
    • 0031715622 scopus 로고    scopus 로고
    • Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis
    • Stolk JN, Boerbooms AMT, DeAbreu RA, et al. Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis. Arthritis Rheum 1998;41:1858-1866.
    • (1998) Arthritis Rheum , vol.41 , pp. 1858-1866
    • Stolk, J.N.1    Boerbooms, A.M.T.2    DeAbreu, R.A.3
  • 2
    • 0032212759 scopus 로고    scopus 로고
    • Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
    • Black AJ, McLeod HL, Capell HA, et al. Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine. Ann Intern Med 1998;129:716-718.
    • (1998) Ann Intern Med , vol.129 , pp. 716-718
    • Black, A.J.1    McLeod, H.L.2    Capell, H.A.3
  • 3
    • 0036668038 scopus 로고    scopus 로고
    • Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: Impact of thiopurine S-methyltransferase polymorphism
    • Schwab M, Schaffeler E, Marx C, et al. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: Impact of thiopurine S-methyltransferase polymorphism. Pharmacogenetics 2002;12:429-436.
    • (2002) Pharmacogenetics , vol.12 , pp. 429-436
    • Schwab, M.1    Schaffeler, E.2    Marx, C.3
  • 4
    • 0023251340 scopus 로고
    • Acute pancreatitis in two dogs given azathioprine and prednisone
    • Moriello KA, Bowen D, Meyer DJ. Acute pancreatitis in two dogs given azathioprine and prednisone. J Am Vet Med Assoc 1987; 191:695-696.
    • (1987) J Am Vet Med Assoc , vol.191 , pp. 695-696
    • Moriello, K.A.1    Bowen, D.2    Meyer, D.J.3
  • 5
    • 0026055098 scopus 로고
    • Acute pancreatitis and bone marrow suppression in a dog given azathioprine
    • Houston DM, Taylor JA. Acute pancreatitis and bone marrow suppression in a dog given azathioprine. Can Vet J 1991;32:496-497.
    • (1991) Can Vet J , vol.32 , pp. 496-497
    • Houston, D.M.1    Taylor, J.A.2
  • 6
    • 0023887370 scopus 로고
    • Azathioprine for treatment of immune-mediated diseases of dogs and cats
    • Beale KM. Azathioprine for treatment of immune-mediated diseases of dogs and cats. J Am Vet Med Assoc 1988;192:1316-1318.
    • (1988) J Am Vet Med Assoc , vol.192 , pp. 1316-1318
    • Beale, K.M.1
  • 7
    • 0026674711 scopus 로고
    • Systemic toxicosis associated with azathioprine administration in domestic cats
    • Beale KM, Altman D, Clemmons RR, Bolon B. Systemic toxicosis associated with azathioprine administration in domestic cats. Am J Vet Res 1992;53:1236-1240.
    • (1992) Am J Vet Res , vol.53 , pp. 1236-1240
    • Beale, K.M.1    Altman, D.2    Clemmons, R.R.3    Bolon, B.4
  • 8
    • 0029958312 scopus 로고    scopus 로고
    • Azathioprine-induced bone marrow toxicity in four dogs
    • Rinkhardt NE, Kruth SA. Azathioprine-induced bone marrow toxicity in four dogs. Can Vet J 1996;37:612-613.
    • (1996) Can Vet J , vol.37 , pp. 612-613
    • Rinkhardt, N.E.1    Kruth, S.A.2
  • 9
    • 0026758498 scopus 로고
    • The clinical pharmacology of 6-mercaptopurine
    • Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992;43:329-339.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 329-339
    • Lennard, L.1
  • 10
    • 0028471670 scopus 로고
    • Rheumatoid arthritis
    • Lewis RM. Rheumatoid arthritis. Vet Clin North Am 1994;24: 697-703.
    • (1994) Vet Clin North Am , vol.24 , pp. 697-703
    • Lewis, R.M.1
  • 12
    • 0021148310 scopus 로고
    • 6-Thioguanine-induced DNA damage as a determinant of cytotoxicity in cultured Chinese hamster ovary cells
    • Christie NT, Drake S, Meyn RE, Nelson JA. 6-Thioguanine-induced DNA damage as a determinant of cytotoxicity in cultured Chinese hamster ovary cells. Cancer Res 1984;44:3665-3671.
    • (1984) Cancer Res , vol.44 , pp. 3665-3671
    • Christie, N.T.1    Drake, S.2    Meyn, R.E.3    Nelson, J.A.4
  • 13
    • 0027405396 scopus 로고
    • Cellular pharmacology of 6-mercaptourine in acute lymphoblastic leukemia
    • Bostrom B, Erdmann G. Cellular pharmacology of 6-mercaptourine in acute lymphoblastic leukemia. Am J Pediatr Hematol/Oncol 1993;15:80-86.
    • (1993) Am J Pediatr Hematol/Oncol , vol.15 , pp. 80-86
    • Bostrom, B.1    Erdmann, G.2
  • 14
    • 0033782140 scopus 로고    scopus 로고
    • A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations
    • Coulthard SA, Rabello C, Robson J, et al. A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations. Br J Hematol 2000;110:599-604.
    • (2000) Br J Hematol , vol.110 , pp. 599-604
    • Coulthard, S.A.1    Rabello, C.2    Robson, J.3
  • 15
    • 0029790730 scopus 로고    scopus 로고
    • Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism
    • Lennard L, Lilleyman JS. Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism. Ther Drug Monitoring 1996;18:328-334.
    • (1996) Ther Drug Monitoring , vol.18 , pp. 328-334
    • Lennard, L.1    Lilleyman, J.S.2
  • 16
    • 0030940405 scopus 로고    scopus 로고
    • Thiopurine methyltransferase activity in the erythrocytes of adults and children: An HPLC-linked assay
    • Micheli V, Jacomelli G, Fioravanti A, et al. Thiopurine methyltransferase activity in the erythrocytes of adults and children: An HPLC-linked assay. Clin Chim Acta 1997;259:161-168.
    • (1997) Clin Chim Acta , vol.259 , pp. 161-168
    • Micheli, V.1    Jacomelli, G.2    Fioravanti, A.3
  • 17
    • 0034067784 scopus 로고    scopus 로고
    • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
    • Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000;118:705-713.
    • (2000) Gastroenterology , vol.118 , pp. 705-713
    • Dubinsky, M.C.1    Lamothe, S.2    Yang, H.Y.3
  • 18
    • 0036202803 scopus 로고    scopus 로고
    • 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
    • Dubinsky MC, Yang HY, Hassard PV, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002;122: 904-915.
    • (2002) Gastroenterology , vol.122 , pp. 904-915
    • Dubinsky, M.C.1    Yang, H.Y.2    Hassard, P.V.3
  • 19
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
    • Lennard L, Lilleyman JS, Van Loon JA, Weinshilboum RM. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 1990;336:225-229.
    • (1990) Lancet , vol.336 , pp. 225-229
    • Lennard, L.1    Lilleyman, J.S.2    Van Loon, J.A.3    Weinshilboum, R.M.4
  • 20
    • 0023119219 scopus 로고
    • Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations
    • Lennard L, Van Loon JA, Lilleyman JS, Weinshilboum RM. Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Phamacol Ther 1987;41:18-25.
    • (1987) Clin Phamacol Ther , vol.41 , pp. 18-25
    • Lennard, L.1    Van Loon, J.A.2    Lilleyman, J.S.3    Weinshilboum, R.M.4
  • 21
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity. J Hum Genet 1980;32:651-662.
    • (1980) J Hum Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 22
    • 0024451147 scopus 로고
    • Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism
    • Lennard L, Van Loon JA, Weinshilboum RM. Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism. Clin Pharmacol Ther 1989;46:149-154.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 149-154
    • Lennard, L.1    Van Loon, J.A.2    Weinshilboum, R.M.3
  • 23
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine deficient child with acute lymphocytic leukemia
    • Evans WE, Homer M, Qin Chu Y, et al. Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine deficient child with acute lymphocytic leukemia. J Pediatr 1991;119: 985-989.
    • (1991) J Pediatr , vol.119 , pp. 985-989
    • Evans, W.E.1    Homer, M.2    Qin Chu, Y.3
  • 24
    • 0035871560 scopus 로고    scopus 로고
    • Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
    • Evans WE, Hon YY, Bomgaars L, et al. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol 2001; 19:2293-2301.
    • (2001) J Clin Oncol , vol.19 , pp. 2293-2301
    • Evans, W.E.1    Hon, Y.Y.2    Bomgaars, L.3
  • 25
    • 18244412860 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase gene polymorphism is predictive of azathioprine-induced myelosuppression in heart transplant recipients
    • Sebbag L, Boucher P, Davelu P, et al. Thiopurine S-methyltransferase gene polymorphism is predictive of azathioprine-induced myelosuppression in heart transplant recipients. Transplantation 2000;69: 1524-1527.
    • (2000) Transplantation , vol.69 , pp. 1524-1527
    • Sebbag, L.1    Boucher, P.2    Davelu, P.3
  • 26
    • 0031933720 scopus 로고    scopus 로고
    • Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency
    • Andersen JB, Szumlanski CL, Weinshilboum RM, Schmiegelow K. Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency. Acta Pediatr 1998;87:108-111.
    • (1998) Acta Pediatr , vol.87 , pp. 108-111
    • Andersen, J.B.1    Szumlanski, C.L.2    Weinshilboum, R.M.3    Schmiegelow, K.4
  • 27
    • 0032801395 scopus 로고    scopus 로고
    • Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine
    • Dervieux T, Medard Y, Baudouin V, et al. Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine. J Clin Pharmacol 1999;48:793-800.
    • (1999) J Clin Pharmacol , vol.48 , pp. 793-800
    • Dervieux, T.1    Medard, Y.2    Baudouin, V.3
  • 28
    • 85046166110 scopus 로고    scopus 로고
    • Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine
    • Jackson AP. Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine. Br J Dermatol 1997;136:132-148.
    • (1997) Br J Dermatol , vol.136 , pp. 132-148
    • Jackson, A.P.1
  • 29
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • Yates CR, Krynetski EY, Loennechen T, et al. Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 1997; 126:608-614.
    • (1997) Ann Intern Med , vol.126 , pp. 608-614
    • Yates, C.R.1    Krynetski, E.Y.2    Loennechen, T.3
  • 30
    • 0026543630 scopus 로고
    • Interethnic difference in thiopurine methyltransferase activity
    • Klemetsdal B, Tollefsen E, Loennechen T, et al. Interethnic difference in thiopurine methyltransferase activity. Clin Pharmacol Ther 1992;51:24-31.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 24-31
    • Klemetsdal, B.1    Tollefsen, E.2    Loennechen, T.3
  • 31
    • 0033434009 scopus 로고    scopus 로고
    • Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals
    • McLeod HL, Pritchard SC, Githang J, et al. Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals. Pharmacogenetics 1999;9:773-776.
    • (1999) Pharmacogenetics , vol.9 , pp. 773-776
    • McLeod, H.L.1    Pritchard, S.C.2    Githang, J.3
  • 32
    • 0032917646 scopus 로고    scopus 로고
    • The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations
    • Collie-Duguid ESR, Pritchard SC, Powrie RH, et al. The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations. Pharmacogenetics 1999;9:37-42.
    • (1999) Pharmacogenetics , vol.9 , pp. 37-42
    • Collie-Duguid, E.S.R.1    Pritchard, S.C.2    Powrie, R.H.3
  • 33
    • 0035050911 scopus 로고    scopus 로고
    • Genotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese
    • Kumagai K, Hiyama K, Ishioka S, et al. Genotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese. Pharmacogenetics 2001;11:275-278.
    • (2001) Pharmacogenetics , vol.11 , pp. 275-278
    • Kumagai, K.1    Hiyama, K.2    Ishioka, S.3
  • 34
    • 0033376417 scopus 로고    scopus 로고
    • Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese
    • Ishioka S, Hiyama K, Sato H, et al. Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese. Intern Med 1999;38:944-947.
    • (1999) Intern Med , vol.38 , pp. 944-947
    • Ishioka, S.1    Hiyama, K.2    Sato, H.3
  • 35
    • 0032898380 scopus 로고    scopus 로고
    • Thiopurine methyltransferase alleles in British and Ghanian populations
    • Ameyaw M-M, Collie-Duguid ESR, Powrie RH, et al. Thiopurine methyltransferase alleles in British and Ghanian populations. Hum Mol Genet 1999;8:367-370.
    • (1999) Hum Mol Genet , vol.8 , pp. 367-370
    • Ameyaw, M.-M.1    Collie-Duguid, E.S.R.2    Powrie, R.H.3
  • 36
    • 0035028961 scopus 로고    scopus 로고
    • Thiopurine methyltransferase activity in the Jewish population of Israel
    • Lowenthal A, Meyerstein N, Ben-Zvi Z. Thiopurine methyltransferase activity in the Jewish population of Israel. J Clin Pharmacol 2001;57:43-46.
    • (2001) J Clin Pharmacol , vol.57 , pp. 43-46
    • Lowenthal, A.1    Meyerstein, N.2    Ben-Zvi, Z.3
  • 37
    • 0036161781 scopus 로고    scopus 로고
    • Interaction between azathioprine and aminosalicylates: An in vivo study in patients with Crohn's disease
    • Dewit O, Vanheuverzwyn R, Deasager JP, Horsmans Y. Interaction between azathioprine and aminosalicylates: An in vivo study in patients with Crohn's disease. Aliment Pharmacol Ther 2002;16:79-85.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 79-85
    • Dewit, O.1    Vanheuverzwyn, R.2    Deasager, J.P.3    Horsmans, Y.4
  • 38
    • 0028917479 scopus 로고
    • Sulfasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine
    • Szumlanski CL, Weinshilboum RM. Sulfasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine. Br J Clin Pharmacol 1995;39:456-459.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 456-459
    • Szumlanski, C.L.1    Weinshilboum, R.M.2
  • 39
    • 0035031348 scopus 로고    scopus 로고
    • Human thiopurine S-methyltransferase activity in uremia and after renal transplantation
    • Weyer N, Kroplin T, Fricke L, Iven H. Human thiopurine S-methyltransferase activity in uremia and after renal transplantation. Eur J Clin Pharmacol 2001;57:129-136.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 129-136
    • Weyer, N.1    Kroplin, T.2    Fricke, L.3    Iven, H.4
  • 40
    • 0030657957 scopus 로고    scopus 로고
    • Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction
    • Lewis LD, Benin A, Szumlanski CL, et al. Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction. Clin Pharmacol Ther 1997;62:464-475.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 464-475
    • Lewis, L.D.1    Benin, A.2    Szumlanski, C.L.3
  • 41
    • 0031450479 scopus 로고    scopus 로고
    • Possibilities for therapeutic drug monitoring of azathioprine: 6-Thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells
    • Bergan S, Rugstad HE, Klemetsdal B, et al. Possibilities for therapeutic drug monitoring of azathioprine: 6-Thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells. Ther Drug Monitoring 1997;19:318-326.
    • (1997) Ther Drug Monitoring , vol.19 , pp. 318-326
    • Bergan, S.1    Rugstad, H.E.2    Klemetsdal, B.3
  • 42
    • 0034277066 scopus 로고    scopus 로고
    • Thiopurine methyltransferase in red blood cells of dogs, cats and horses
    • White S, Rosychuk RAW, Outerbridge DA, et al. Thiopurine methyltransferase in red blood cells of dogs, cats and horses. J Vet Intern Med 2000;14:499-502.
    • (2000) J Vet Intern Med , vol.14 , pp. 499-502
    • White, S.1    Rosychuk, R.A.W.2    Outerbridge, D.A.3
  • 43
    • 0034277452 scopus 로고    scopus 로고
    • Demonstration of thiopurine methyltransferase activity in the erythrocytes of cats
    • Foster AP, Shaw SE, Duley JA, et al. Demonstration of thiopurine methyltransferase activity in the erythrocytes of cats. J Vet Intern Med 2000;2000:552-554.
    • (2000) J Vet Intern Med , vol.2000 , pp. 552-554
    • Foster, A.P.1    Shaw, S.E.2    Duley, J.A.3
  • 44
    • 0017880983 scopus 로고
    • Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
    • Weinshilboum RM, Raymond FA, Pazmino PA. Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties. Clin Chim Acta 1978;85:323-333.
    • (1978) Clin Chim Acta , vol.85 , pp. 323-333
    • Weinshilboum, R.M.1    Raymond, F.A.2    Pazmino, P.A.3
  • 46
    • 0034036355 scopus 로고    scopus 로고
    • Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease
    • Kader HA, Wenner WJ, Telega GW, Baldassano RN. Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease. J Clin Gastroenterol 2000;30:409-413.
    • (2000) J Clin Gastroenterol , vol.30 , pp. 409-413
    • Kader, H.A.1    Wenner, W.J.2    Telega, G.W.3    Baldassano, R.N.4
  • 47
    • 0032732591 scopus 로고    scopus 로고
    • Identification of thiopurine methyltransferase (TPMT) polymorphisms cannot predict myelosuppression in systemic lupus erythematous patients taking azathioprine
    • Naughton MA, Battaglia E, O'Brien S, et al. Identification of thiopurine methyltransferase (TPMT) polymorphisms cannot predict myelosuppression in systemic lupus erythematous patients taking azathioprine. Rheumatology 1999;38:640-644.
    • (1999) Rheumatology , vol.38 , pp. 640-644
    • Naughton, M.A.1    Battaglia, E.2    O'Brien, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.