-
1
-
-
0031715622
-
Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis
-
Stolk JN, Boerbooms AMT, DeAbreu RA, et al. Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis. Arthritis Rheum 1998;41:1858-1866.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1858-1866
-
-
Stolk, J.N.1
Boerbooms, A.M.T.2
DeAbreu, R.A.3
-
2
-
-
0032212759
-
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
-
Black AJ, McLeod HL, Capell HA, et al. Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine. Ann Intern Med 1998;129:716-718.
-
(1998)
Ann Intern Med
, vol.129
, pp. 716-718
-
-
Black, A.J.1
McLeod, H.L.2
Capell, H.A.3
-
3
-
-
0036668038
-
Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: Impact of thiopurine S-methyltransferase polymorphism
-
Schwab M, Schaffeler E, Marx C, et al. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: Impact of thiopurine S-methyltransferase polymorphism. Pharmacogenetics 2002;12:429-436.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 429-436
-
-
Schwab, M.1
Schaffeler, E.2
Marx, C.3
-
4
-
-
0023251340
-
Acute pancreatitis in two dogs given azathioprine and prednisone
-
Moriello KA, Bowen D, Meyer DJ. Acute pancreatitis in two dogs given azathioprine and prednisone. J Am Vet Med Assoc 1987; 191:695-696.
-
(1987)
J Am Vet Med Assoc
, vol.191
, pp. 695-696
-
-
Moriello, K.A.1
Bowen, D.2
Meyer, D.J.3
-
5
-
-
0026055098
-
Acute pancreatitis and bone marrow suppression in a dog given azathioprine
-
Houston DM, Taylor JA. Acute pancreatitis and bone marrow suppression in a dog given azathioprine. Can Vet J 1991;32:496-497.
-
(1991)
Can Vet J
, vol.32
, pp. 496-497
-
-
Houston, D.M.1
Taylor, J.A.2
-
6
-
-
0023887370
-
Azathioprine for treatment of immune-mediated diseases of dogs and cats
-
Beale KM. Azathioprine for treatment of immune-mediated diseases of dogs and cats. J Am Vet Med Assoc 1988;192:1316-1318.
-
(1988)
J Am Vet Med Assoc
, vol.192
, pp. 1316-1318
-
-
Beale, K.M.1
-
7
-
-
0026674711
-
Systemic toxicosis associated with azathioprine administration in domestic cats
-
Beale KM, Altman D, Clemmons RR, Bolon B. Systemic toxicosis associated with azathioprine administration in domestic cats. Am J Vet Res 1992;53:1236-1240.
-
(1992)
Am J Vet Res
, vol.53
, pp. 1236-1240
-
-
Beale, K.M.1
Altman, D.2
Clemmons, R.R.3
Bolon, B.4
-
8
-
-
0029958312
-
Azathioprine-induced bone marrow toxicity in four dogs
-
Rinkhardt NE, Kruth SA. Azathioprine-induced bone marrow toxicity in four dogs. Can Vet J 1996;37:612-613.
-
(1996)
Can Vet J
, vol.37
, pp. 612-613
-
-
Rinkhardt, N.E.1
Kruth, S.A.2
-
9
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992;43:329-339.
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
10
-
-
0028471670
-
Rheumatoid arthritis
-
Lewis RM. Rheumatoid arthritis. Vet Clin North Am 1994;24: 697-703.
-
(1994)
Vet Clin North Am
, vol.24
, pp. 697-703
-
-
Lewis, R.M.1
-
12
-
-
0021148310
-
6-Thioguanine-induced DNA damage as a determinant of cytotoxicity in cultured Chinese hamster ovary cells
-
Christie NT, Drake S, Meyn RE, Nelson JA. 6-Thioguanine-induced DNA damage as a determinant of cytotoxicity in cultured Chinese hamster ovary cells. Cancer Res 1984;44:3665-3671.
-
(1984)
Cancer Res
, vol.44
, pp. 3665-3671
-
-
Christie, N.T.1
Drake, S.2
Meyn, R.E.3
Nelson, J.A.4
-
13
-
-
0027405396
-
Cellular pharmacology of 6-mercaptourine in acute lymphoblastic leukemia
-
Bostrom B, Erdmann G. Cellular pharmacology of 6-mercaptourine in acute lymphoblastic leukemia. Am J Pediatr Hematol/Oncol 1993;15:80-86.
-
(1993)
Am J Pediatr Hematol/Oncol
, vol.15
, pp. 80-86
-
-
Bostrom, B.1
Erdmann, G.2
-
14
-
-
0033782140
-
A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations
-
Coulthard SA, Rabello C, Robson J, et al. A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations. Br J Hematol 2000;110:599-604.
-
(2000)
Br J Hematol
, vol.110
, pp. 599-604
-
-
Coulthard, S.A.1
Rabello, C.2
Robson, J.3
-
15
-
-
0029790730
-
Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism
-
Lennard L, Lilleyman JS. Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism. Ther Drug Monitoring 1996;18:328-334.
-
(1996)
Ther Drug Monitoring
, vol.18
, pp. 328-334
-
-
Lennard, L.1
Lilleyman, J.S.2
-
16
-
-
0030940405
-
Thiopurine methyltransferase activity in the erythrocytes of adults and children: An HPLC-linked assay
-
Micheli V, Jacomelli G, Fioravanti A, et al. Thiopurine methyltransferase activity in the erythrocytes of adults and children: An HPLC-linked assay. Clin Chim Acta 1997;259:161-168.
-
(1997)
Clin Chim Acta
, vol.259
, pp. 161-168
-
-
Micheli, V.1
Jacomelli, G.2
Fioravanti, A.3
-
17
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000;118:705-713.
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
-
18
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky MC, Yang HY, Hassard PV, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002;122: 904-915.
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.Y.2
Hassard, P.V.3
-
19
-
-
0025331198
-
Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
-
Lennard L, Lilleyman JS, Van Loon JA, Weinshilboum RM. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 1990;336:225-229.
-
(1990)
Lancet
, vol.336
, pp. 225-229
-
-
Lennard, L.1
Lilleyman, J.S.2
Van Loon, J.A.3
Weinshilboum, R.M.4
-
20
-
-
0023119219
-
Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations
-
Lennard L, Van Loon JA, Lilleyman JS, Weinshilboum RM. Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Phamacol Ther 1987;41:18-25.
-
(1987)
Clin Phamacol Ther
, vol.41
, pp. 18-25
-
-
Lennard, L.1
Van Loon, J.A.2
Lilleyman, J.S.3
Weinshilboum, R.M.4
-
21
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity. J Hum Genet 1980;32:651-662.
-
(1980)
J Hum Genet
, vol.32
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
22
-
-
0024451147
-
Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism
-
Lennard L, Van Loon JA, Weinshilboum RM. Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism. Clin Pharmacol Ther 1989;46:149-154.
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 149-154
-
-
Lennard, L.1
Van Loon, J.A.2
Weinshilboum, R.M.3
-
23
-
-
0025837127
-
Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine deficient child with acute lymphocytic leukemia
-
Evans WE, Homer M, Qin Chu Y, et al. Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine deficient child with acute lymphocytic leukemia. J Pediatr 1991;119: 985-989.
-
(1991)
J Pediatr
, vol.119
, pp. 985-989
-
-
Evans, W.E.1
Homer, M.2
Qin Chu, Y.3
-
24
-
-
0035871560
-
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
-
Evans WE, Hon YY, Bomgaars L, et al. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol 2001; 19:2293-2301.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2293-2301
-
-
Evans, W.E.1
Hon, Y.Y.2
Bomgaars, L.3
-
25
-
-
18244412860
-
Thiopurine S-methyltransferase gene polymorphism is predictive of azathioprine-induced myelosuppression in heart transplant recipients
-
Sebbag L, Boucher P, Davelu P, et al. Thiopurine S-methyltransferase gene polymorphism is predictive of azathioprine-induced myelosuppression in heart transplant recipients. Transplantation 2000;69: 1524-1527.
-
(2000)
Transplantation
, vol.69
, pp. 1524-1527
-
-
Sebbag, L.1
Boucher, P.2
Davelu, P.3
-
26
-
-
0031933720
-
Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency
-
Andersen JB, Szumlanski CL, Weinshilboum RM, Schmiegelow K. Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency. Acta Pediatr 1998;87:108-111.
-
(1998)
Acta Pediatr
, vol.87
, pp. 108-111
-
-
Andersen, J.B.1
Szumlanski, C.L.2
Weinshilboum, R.M.3
Schmiegelow, K.4
-
27
-
-
0032801395
-
Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine
-
Dervieux T, Medard Y, Baudouin V, et al. Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine. J Clin Pharmacol 1999;48:793-800.
-
(1999)
J Clin Pharmacol
, vol.48
, pp. 793-800
-
-
Dervieux, T.1
Medard, Y.2
Baudouin, V.3
-
28
-
-
85046166110
-
Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine
-
Jackson AP. Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine. Br J Dermatol 1997;136:132-148.
-
(1997)
Br J Dermatol
, vol.136
, pp. 132-148
-
-
Jackson, A.P.1
-
29
-
-
0030934850
-
Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
-
Yates CR, Krynetski EY, Loennechen T, et al. Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 1997; 126:608-614.
-
(1997)
Ann Intern Med
, vol.126
, pp. 608-614
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
-
30
-
-
0026543630
-
Interethnic difference in thiopurine methyltransferase activity
-
Klemetsdal B, Tollefsen E, Loennechen T, et al. Interethnic difference in thiopurine methyltransferase activity. Clin Pharmacol Ther 1992;51:24-31.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 24-31
-
-
Klemetsdal, B.1
Tollefsen, E.2
Loennechen, T.3
-
31
-
-
0033434009
-
Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals
-
McLeod HL, Pritchard SC, Githang J, et al. Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals. Pharmacogenetics 1999;9:773-776.
-
(1999)
Pharmacogenetics
, vol.9
, pp. 773-776
-
-
McLeod, H.L.1
Pritchard, S.C.2
Githang, J.3
-
32
-
-
0032917646
-
The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations
-
Collie-Duguid ESR, Pritchard SC, Powrie RH, et al. The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations. Pharmacogenetics 1999;9:37-42.
-
(1999)
Pharmacogenetics
, vol.9
, pp. 37-42
-
-
Collie-Duguid, E.S.R.1
Pritchard, S.C.2
Powrie, R.H.3
-
33
-
-
0035050911
-
Genotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese
-
Kumagai K, Hiyama K, Ishioka S, et al. Genotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese. Pharmacogenetics 2001;11:275-278.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 275-278
-
-
Kumagai, K.1
Hiyama, K.2
Ishioka, S.3
-
34
-
-
0033376417
-
Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese
-
Ishioka S, Hiyama K, Sato H, et al. Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese. Intern Med 1999;38:944-947.
-
(1999)
Intern Med
, vol.38
, pp. 944-947
-
-
Ishioka, S.1
Hiyama, K.2
Sato, H.3
-
35
-
-
0032898380
-
Thiopurine methyltransferase alleles in British and Ghanian populations
-
Ameyaw M-M, Collie-Duguid ESR, Powrie RH, et al. Thiopurine methyltransferase alleles in British and Ghanian populations. Hum Mol Genet 1999;8:367-370.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 367-370
-
-
Ameyaw, M.-M.1
Collie-Duguid, E.S.R.2
Powrie, R.H.3
-
36
-
-
0035028961
-
Thiopurine methyltransferase activity in the Jewish population of Israel
-
Lowenthal A, Meyerstein N, Ben-Zvi Z. Thiopurine methyltransferase activity in the Jewish population of Israel. J Clin Pharmacol 2001;57:43-46.
-
(2001)
J Clin Pharmacol
, vol.57
, pp. 43-46
-
-
Lowenthal, A.1
Meyerstein, N.2
Ben-Zvi, Z.3
-
37
-
-
0036161781
-
Interaction between azathioprine and aminosalicylates: An in vivo study in patients with Crohn's disease
-
Dewit O, Vanheuverzwyn R, Deasager JP, Horsmans Y. Interaction between azathioprine and aminosalicylates: An in vivo study in patients with Crohn's disease. Aliment Pharmacol Ther 2002;16:79-85.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 79-85
-
-
Dewit, O.1
Vanheuverzwyn, R.2
Deasager, J.P.3
Horsmans, Y.4
-
38
-
-
0028917479
-
Sulfasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine
-
Szumlanski CL, Weinshilboum RM. Sulfasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine. Br J Clin Pharmacol 1995;39:456-459.
-
(1995)
Br J Clin Pharmacol
, vol.39
, pp. 456-459
-
-
Szumlanski, C.L.1
Weinshilboum, R.M.2
-
39
-
-
0035031348
-
Human thiopurine S-methyltransferase activity in uremia and after renal transplantation
-
Weyer N, Kroplin T, Fricke L, Iven H. Human thiopurine S-methyltransferase activity in uremia and after renal transplantation. Eur J Clin Pharmacol 2001;57:129-136.
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 129-136
-
-
Weyer, N.1
Kroplin, T.2
Fricke, L.3
Iven, H.4
-
40
-
-
0030657957
-
Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction
-
Lewis LD, Benin A, Szumlanski CL, et al. Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction. Clin Pharmacol Ther 1997;62:464-475.
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 464-475
-
-
Lewis, L.D.1
Benin, A.2
Szumlanski, C.L.3
-
41
-
-
0031450479
-
Possibilities for therapeutic drug monitoring of azathioprine: 6-Thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells
-
Bergan S, Rugstad HE, Klemetsdal B, et al. Possibilities for therapeutic drug monitoring of azathioprine: 6-Thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells. Ther Drug Monitoring 1997;19:318-326.
-
(1997)
Ther Drug Monitoring
, vol.19
, pp. 318-326
-
-
Bergan, S.1
Rugstad, H.E.2
Klemetsdal, B.3
-
42
-
-
0034277066
-
Thiopurine methyltransferase in red blood cells of dogs, cats and horses
-
White S, Rosychuk RAW, Outerbridge DA, et al. Thiopurine methyltransferase in red blood cells of dogs, cats and horses. J Vet Intern Med 2000;14:499-502.
-
(2000)
J Vet Intern Med
, vol.14
, pp. 499-502
-
-
White, S.1
Rosychuk, R.A.W.2
Outerbridge, D.A.3
-
43
-
-
0034277452
-
Demonstration of thiopurine methyltransferase activity in the erythrocytes of cats
-
Foster AP, Shaw SE, Duley JA, et al. Demonstration of thiopurine methyltransferase activity in the erythrocytes of cats. J Vet Intern Med 2000;2000:552-554.
-
(2000)
J Vet Intern Med
, vol.2000
, pp. 552-554
-
-
Foster, A.P.1
Shaw, S.E.2
Duley, J.A.3
-
44
-
-
0017880983
-
Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
-
Weinshilboum RM, Raymond FA, Pazmino PA. Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties. Clin Chim Acta 1978;85:323-333.
-
(1978)
Clin Chim Acta
, vol.85
, pp. 323-333
-
-
Weinshilboum, R.M.1
Raymond, F.A.2
Pazmino, P.A.3
-
46
-
-
0034036355
-
Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease
-
Kader HA, Wenner WJ, Telega GW, Baldassano RN. Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease. J Clin Gastroenterol 2000;30:409-413.
-
(2000)
J Clin Gastroenterol
, vol.30
, pp. 409-413
-
-
Kader, H.A.1
Wenner, W.J.2
Telega, G.W.3
Baldassano, R.N.4
-
47
-
-
0032732591
-
Identification of thiopurine methyltransferase (TPMT) polymorphisms cannot predict myelosuppression in systemic lupus erythematous patients taking azathioprine
-
Naughton MA, Battaglia E, O'Brien S, et al. Identification of thiopurine methyltransferase (TPMT) polymorphisms cannot predict myelosuppression in systemic lupus erythematous patients taking azathioprine. Rheumatology 1999;38:640-644.
-
(1999)
Rheumatology
, vol.38
, pp. 640-644
-
-
Naughton, M.A.1
Battaglia, E.2
O'Brien, S.3
|