메뉴 건너뛰기




Volumn 14, Issue 1, 2005, Pages 53-61

Genetic factors in pancreatitis

Author keywords

CFTR; Immune modulating genes; Pancreatitis; PRSS1 mutations; SPINK 1 mutations

Indexed keywords

TRYPSINOGEN;

EID: 16244418401     PISSN: 12214167     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (92)
  • 1
    • 0021638331 scopus 로고
    • Classification of pancreatitis
    • Sarner M, Cotton PB. Classification of pancreatitis. Gut 1984; 25: 756-759.
    • (1984) Gut , vol.25 , pp. 756-759
    • Sarner, M.1    Cotton, P.B.2
  • 2
    • 0021997199 scopus 로고
    • Revised classification of pancreatitis. Report of the Second International Symposium on the Classification of Pancreatitis. Marseille, France, March 28-30, 1984
    • Singer MV, Gyr K, Sarles H. Revised classification of pancreatitis. Report of the Second International Symposium on the Classification of Pancreatitis. Marseille, France, March 28-30, 1984. Gastroenterology 1985; 89: 683-685.
    • (1985) Gastroenterology , vol.89 , pp. 683-685
    • Singer, M.V.1    Gyr, K.2    Sarles, H.3
  • 3
    • 0024356795 scopus 로고
    • The pancreatitis, classification of Marseille-Rome 1988
    • Sarles H, Adler G, Dani R et al. The pancreatitis, classification of Marseille-Rome 1988. Scand J Gastroenterol 1989; 24: 641-642.
    • (1989) Scand J Gastroenterol , vol.24 , pp. 641-642
    • Sarles, H.1    Adler, G.2    Dani, R.3
  • 4
    • 0035109764 scopus 로고    scopus 로고
    • Chronic pancreatitis: Diagnosis, classification and new genetic developments
    • Etemad B, Whitcomb DC. Chronic pancreatitis: diagnosis, classification and new genetic developments. Gastroenterology 2001; 120: 682-707.
    • (2001) Gastroenterology , vol.120 , pp. 682-707
    • Etemad, B.1    Whitcomb, D.C.2
  • 5
    • 76949133404 scopus 로고
    • Pedigree of a family with hereditary chronic relapsing pancreatitis
    • Comfort M, Steinberg A. Pedigree of a family with hereditary chronic relapsing pancreatitis. Gastroenterology 1952; 21: 54-63.
    • (1952) Gastroenterology , vol.21 , pp. 54-63
    • Comfort, M.1    Steinberg, A.2
  • 6
    • 0030848153 scopus 로고    scopus 로고
    • Clinical characteristics of hereditary pancreatitis in a large family based on high-risk haplotype
    • Sossenheimer M, Aston C, Ehrlich G et al. Clinical characteristics of hereditary pancreatitis in a large family based on high-risk haplotype. Am J Gastroenterol 1997; 92: 1113-1116.
    • (1997) Am J Gastroenterol , vol.92 , pp. 1113-1116
    • Sossenheimer, M.1    Aston, C.2    Ehrlich, G.3
  • 7
    • 0030017252 scopus 로고    scopus 로고
    • An exceptional genealogy for hereditary chronic pancreatitis
    • Le Bodic L, Schnee M, Georgelin T et al. An exceptional genealogy for hereditary chronic pancreatitis. Dig Dis Sci 1996; 41: 1504-1510.
    • (1996) Dig Dis Sci , vol.41 , pp. 1504-1510
    • Le Bodic, L.1    Schnee, M.2    Georgelin, T.3
  • 9
    • 13344286299 scopus 로고    scopus 로고
    • The hereditary pancreatitis gene maps to long arm of chromosome 7
    • Le Bodic L, Bignon JD, Raguenes O et al. The hereditary pancreatitis gene maps to long arm of chromosome 7. Hum Mol Genet 1996; 5: 549-554.
    • (1996) Hum Mol Genet , vol.5 , pp. 549-554
    • Le Bodic, L.1    Bignon, J.D.2    Raguenes, O.3
  • 10
    • 0029941559 scopus 로고    scopus 로고
    • A gene for hereditary pancreatitis maps to chromosome 7q35
    • Whitcomb DC, Preston RA, Aston CE et al. A gene for hereditary pancreatitis maps to chromosome 7q35. Gastroenterology 1996; 110: 1975-1980.
    • (1996) Gastroenterology , vol.110 , pp. 1975-1980
    • Whitcomb, D.C.1    Preston, R.A.2    Aston, C.E.3
  • 11
    • 0038644692 scopus 로고    scopus 로고
    • Genetic factors in pancreatitis
    • Grendell JH. Genetic factors in pancreatitis. Curr Gastroenterol Rep 2003; 5: 105-109
    • (2003) Curr Gastroenterol Rep , vol.5 , pp. 105-109
    • Grendell, J.H.1
  • 12
    • 0019353008 scopus 로고
    • Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis
    • Scheele G, Bartelt D, Bieger W. Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis. Gastroenterology 1981; 80: 461-473.
    • (1981) Gastroenterology , vol.80 , pp. 461-473
    • Scheele, G.1    Bartelt, D.2    Bieger, W.3
  • 13
    • 0021363565 scopus 로고
    • Mesotrypsin: A new inhibitor resistant protease from a zymogen in human pancreatic tissue and fluid
    • Rinderknecht H, Rener IG, Abramson SB, Carmack C. Mesotrypsin: a new inhibitor resistant protease from a zymogen in human pancreatic tissue and fluid. Gastroenterology 1984; 86: 681-692.
    • (1984) Gastroenterology , vol.86 , pp. 681-692
    • Rinderknecht, H.1    Rener, I.G.2    Abramson, S.B.3    Carmack, C.4
  • 14
    • 0030017526 scopus 로고    scopus 로고
    • The complete 685-kilobase DNA sequence of the human beta T cell receptor locus
    • Rowen L, Koop BF, Hood L. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. Science 1996; 272: 1755-1762.
    • (1996) Science , vol.272 , pp. 1755-1762
    • Rowen, L.1    Koop, B.F.2    Hood, L.3
  • 15
    • 0030446265 scopus 로고    scopus 로고
    • Linkage studies in a large kindred with hereditary pancreatitis confirms mapping of the gene to a 16-cM region on 7q
    • Pandya A, Blanton SH, Landa B et al. Linkage studies in a large kindred with hereditary pancreatitis confirms mapping of the gene to a 16-cM region on 7q. Genomics 1996; 38: 227-230.
    • (1996) Genomics , vol.38 , pp. 227-230
    • Pandya, A.1    Blanton, S.H.2    Landa, B.3
  • 16
    • 5444268051 scopus 로고    scopus 로고
    • Value of genetic testing in the management of pancreatitis
    • Whitcomb DC. Value of genetic testing in the management of pancreatitis. Gut 2004; 53: 1710-1717.
    • (2004) Gut , vol.53 , pp. 1710-1717
    • Whitcomb, D.C.1
  • 17
    • 0030604725 scopus 로고    scopus 로고
    • Crystal structure of human trypsin 1: Unexpected phosphorylation of Tyr 151
    • Gaboriaud C, Serre L, Guy Crotte O et al. Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr 151. J Mol Biol 1996; 259: 995-1010.
    • (1996) J Mol Biol , vol.259 , pp. 995-1010
    • Gaboriaud, C.1    Serre, L.2    Guy Crotte, O.3
  • 18
    • 0002169463 scopus 로고    scopus 로고
    • Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122->Cys) that alters autoactivation and autodegradation of cationic trypsinogen
    • Simon P, Weiss FU, Sahin-Tóth M et al. Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122->Cys) that alters autoactivation and autodegradation of cationic trypsinogen. J Biol Chem 2001; 21: 21.
    • (2001) J Biol Chem , vol.21 , pp. 21
    • Simon, P.1    Weiss, F.U.2    Sahin-Tóth, M.3
  • 19
    • 1342333658 scopus 로고    scopus 로고
    • Signal transduction, calcium and acute pancreatitis
    • Sutton R, Criddle D, Raraty MG et al. Signal transduction, calcium and acute pancreatitis. Pancreatology 2003; 3: 497-505.
    • (2003) Pancreatology , vol.3 , pp. 497-505
    • Sutton, R.1    Criddle, D.2    Raraty, M.G.3
  • 20
    • 0023125973 scopus 로고
    • The cell biology of experimental pancreatitis
    • Steer ML, Meldolesi J. The cell biology of experimental pancreatitis. N Engl J Med 1987; 316: 144-156.
    • (1987) N Engl J Med , vol.316 , pp. 144-156
    • Steer, M.L.1    Meldolesi, J.2
  • 21
    • 0002884935 scopus 로고
    • Pancreatic secretory enzymes
    • Go VLW, Di Magno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA (eds). New York: Raven Press
    • nd Ed. New York: Raven Press, 1993: 219-251.
    • (1993) nd Ed. , pp. 219-251
    • Rinderknecht, H.1
  • 22
    • 16244393935 scopus 로고    scopus 로고
    • Mechanisms of disease: Advances in understanding the mechanisms leading to chronic pancreatitis
    • Whitcomb DC. Mechanisms of disease: advances in understanding the mechanisms leading to chronic pancreatitis. Nat Clin Pract Gastroenterol Hepatol 2004; 1: 46-52.
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , pp. 46-52
    • Whitcomb, D.C.1
  • 25
    • 0018725411 scopus 로고
    • Comparative studies on the mechanisms of activation of the two human trypsinogens
    • Colomb E, Figarella C. Comparative studies on the mechanisms of activation of the two human trypsinogens. Biochem Biophys Acta 1979; 571: 343-351.
    • (1979) Biochem Biophys Acta , vol.571 , pp. 343-351
    • Colomb, E.1    Figarella, C.2
  • 26
    • 0032775422 scopus 로고
    • Hereditary pancreatitis: New insight into acute and chronic pancreatitis
    • Whitcomb DC. Hereditary pancreatitis: new insight into acute and chronic pancreatitis. Gut 1994; 45: 317-322.
    • (1994) Gut , vol.45 , pp. 317-322
    • Whitcomb, D.C.1
  • 27
    • 10144246566 scopus 로고    scopus 로고
    • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
    • Whitcomb DC, Gorry MC, Preston RA et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996; 14; 141-145.
    • (1996) Nat Genet , vol.14 , pp. 141-145
    • Whitcomb, D.C.1    Gorry, M.C.2    Preston, R.A.3
  • 28
    • 0030813082 scopus 로고    scopus 로고
    • Multiple mutations in the cationic trypsinogen gene are associated with hereditary pancreatitis
    • Gorry MC, Gabbaizedeh D, Furey W et al. Multiple mutations in the cationic trypsinogen gene are associated with hereditary pancreatitis. Gastroenterology 1997; 113: 1063-1068.
    • (1997) Gastroenterology , vol.113 , pp. 1063-1068
    • Gorry, M.C.1    Gabbaizedeh, D.2    Furey, W.3
  • 29
    • 0035553707 scopus 로고    scopus 로고
    • Hereditary pancreatitis in North America: The Pittsburgh Midwest Multi-Center Pancreatic Study Group
    • Applebaum-Shapiro SE, Finch R, Pfützer RH et al. Hereditary pancreatitis in North America: The Pittsburgh Midwest Multi-Center Pancreatic Study Group. Pancreatology 2001; 1: 439-443.
    • (2001) Pancreatology , vol.1 , pp. 439-443
    • Applebaum-Shapiro, S.E.1    Finch, R.2    Pfützer, R.H.3
  • 30
    • 0034687560 scopus 로고    scopus 로고
    • Gain-of function mutation associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen
    • Sahin-Tóth M, Tóth M. Gain-of function mutation associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen. Biochem Biophys Res Commun 2000; 278: 286-289.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 286-289
    • Sahin-Tóth, M.1    Tóth, M.2
  • 31
    • 0031776625 scopus 로고    scopus 로고
    • Mutations of the cationic trypsinogen in hereditary pancreatitis
    • Teich N, Mössner J, Keim V. Mutations of the cationic trypsinogen in hereditary pancreatitis. Hum Mut 1998; 12: 39-43.
    • (1998) Hum Mut , vol.12 , pp. 39-43
    • Teich, N.1    Mössner, J.2    Keim, V.3
  • 32
    • 0032988134 scopus 로고    scopus 로고
    • Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis
    • Nishimori I, Kamakura M, Fujikawa-Abachi K et al. Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis. Gut 1999; 44: 259-263.
    • (1999) Gut , vol.44 , pp. 259-263
    • Nishimori, I.1    Kamakura, M.2    Fujikawa-Abachi, K.3
  • 33
    • 0018150025 scopus 로고
    • Hereditary pancreatitis in England and Wales
    • Sibert JR. Hereditary pancreatitis in England and Wales. J Med Genet 1978; 15: 189-201.
    • (1978) J Med Genet , vol.15 , pp. 189-201
    • Sibert, J.R.1
  • 35
    • 0030975440 scopus 로고    scopus 로고
    • Hereditary pancreatitis and the risk of pancreatic cancer
    • Lowenfels A, Maisonneuve P, Di Magno E et al. Hereditary pancreatitis and the risk of pancreatic cancer. J Natl Cancer Inst 1997; 89: 442-446.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 442-446
    • Lowenfels, A.1    Maisonneuve, P.2    Di Magno, E.3
  • 36
    • 0035080006 scopus 로고    scopus 로고
    • Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins
    • Amann ST, Gates LK, Aston CE et al. Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins. Gut 2001; 48: 542-547.
    • (2001) Gut , vol.48 , pp. 542-547
    • Amann, S.T.1    Gates, L.K.2    Aston, C.E.3
  • 37
    • 0032993541 scopus 로고    scopus 로고
    • A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with recurrent acute and chronic pancreatitis
    • Witt H, Luck W, Becker M. A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with recurrent acute and chronic pancreatitis. Gastroenterology 1999; 117: 7-10.
    • (1999) Gastroenterology , vol.117 , pp. 7-10
    • Witt, H.1    Luck, W.2    Becker, M.3
  • 38
    • 2442723724 scopus 로고    scopus 로고
    • Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis
    • Férec O, Raguénès O, Salomon R et al. Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis. J Med Genet 1999; 36: 228-232.
    • (1999) J Med Genet , vol.36 , pp. 228-232
    • Férec, O.1    Raguénès, O.2    Salomon, R.3
  • 39
    • 0033866202 scopus 로고    scopus 로고
    • Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation
    • Teich N, Ockenga J, Hoffmeister A et al. Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation. Gastroenterology 2000; 119: 461-465.
    • (2000) Gastroenterology , vol.119 , pp. 461-465
    • Teich, N.1    Ockenga, J.2    Hoffmeister, A.3
  • 40
    • 0035093636 scopus 로고    scopus 로고
    • Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis
    • Chen JM, Piepoli Bis A, Le Bodic L et al. Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis. Clin Genet 2001; 59: 189-193.
    • (2001) Clin Genet , vol.59 , pp. 189-193
    • Chen, J.M.1    Piepoli Bis, A.2    Le Bodic, L.3
  • 41
    • 0035714189 scopus 로고    scopus 로고
    • R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis
    • Tautermann G, Ruebsamen H, Beck M et al. R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis. Digestion 2001; 64: 226-232.
    • (2001) Digestion , vol.64 , pp. 226-232
    • Tautermann, G.1    Ruebsamen, H.2    Beck, M.3
  • 42
    • 0036177587 scopus 로고    scopus 로고
    • Mutational screening of patients with nonalcoholic chronic pancreatitis: Identification of further trypsinogen variants
    • Teich N, Bauer N, Mössner J. Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants. Am J Gastroenterol 2002; 97: 341-346.
    • (2002) Am J Gastroenterol , vol.97 , pp. 341-346
    • Teich, N.1    Bauer, N.2    Mössner, J.3
  • 43
    • 18144434576 scopus 로고    scopus 로고
    • Chronic pancreatitis and cystic fibrosis
    • Witt H. Chronic pancreatitis and cystic fibrosis. Gut 2003; 52(suppl II): 31-41.
    • (2003) Gut , vol.52 , Issue.SUPPL. II , pp. 31-41
    • Witt, H.1
  • 44
    • 9144233558 scopus 로고    scopus 로고
    • Interaction between trypsinogen isoforms in genetically determined pancreatitis: Mutation E79K in cationic trypsinogen (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2)
    • Teich N, Le Marechal C, Kukor Z et al. Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsinogen (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2). Hum Mutat 2004; 23: 22-31.
    • (2004) Hum Mutat , vol.23 , pp. 22-31
    • Teich, N.1    Le Marechal, C.2    Kukor, Z.3
  • 45
    • 0242493163 scopus 로고    scopus 로고
    • Idiopathic vs hereditary pancreatitis
    • Keim V, Teich N. Idiopathic vs hereditary pancreatitis. JAMA 2003; 289: 983-984.
    • (2003) JAMA , vol.289 , pp. 983-984
    • Keim, V.1    Teich, N.2
  • 46
    • 2442727497 scopus 로고    scopus 로고
    • Screening for mutations of the cationic trypsinogen gene: Are they of relevance in chronic alcoholic pancreatitis?
    • Teich N, Mösner J, Keim V. Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis? Gut 1999; 44: 413-416.
    • (1999) Gut , vol.44 , pp. 413-416
    • Teich, N.1    Mösner, J.2    Keim, V.3
  • 47
    • 0034508638 scopus 로고    scopus 로고
    • Pancreatitis fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene
    • Hassan Z, Mohan V, McDermott MF et al. Pancreatitis fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene. Diabetes Metab Rev 2000; 16: 454-457.
    • (2000) Diabetes Metab Rev , vol.16 , pp. 454-457
    • Hassan, Z.1    Mohan, V.2    McDermott, M.F.3
  • 48
    • 0031695080 scopus 로고    scopus 로고
    • Lack of R117H mutation in the cationic trypsinogen gene in patients with tropical pancreatitis from Bangladesh
    • Rossi L, Withcomb DC, Ehrlich GD et al. Lack of R117H mutation in the cationic trypsinogen gene in patients with tropical pancreatitis from Bangladesh. Pancreas 1998; 17: 278-280.
    • (1998) Pancreas , vol.17 , pp. 278-280
    • Rossi, L.1    Withcomb, D.C.2    Ehrlich, G.D.3
  • 49
    • 7244237535 scopus 로고    scopus 로고
    • Systematic overviews of genetic variants of the cationic trypsinogen and SPINK 1 in pancreatitis patients
    • Durie P, Lerch MM, Lowenfels AB et al (eds). Basel: Karger
    • Teich N, Mösner J, Keim V. Systematic overviews of genetic variants of the cationic trypsinogen and SPINK 1 in pancreatitis patients. In: Durie P, Lerch MM, Lowenfels AB et al (eds). Genetic disorders of the exocrine pancreas: an overview and update. Basel: Karger 2002: 20-22.
    • (2002) Genetic Disorders of the Exocrine Pancreas: An Overview and Update , pp. 20-22
    • Teich, N.1    Mösner, J.2    Keim, V.3
  • 50
    • 7244261433 scopus 로고    scopus 로고
    • Hereditary diseases of the pancreas
    • Yamada T, Albers DH, Laine L et al (eds). Philadelphia: Lippincott Williams and Wilkins
    • Whitcomb DC. Hereditary diseases of the pancreas. In: Yamada T, Albers DH, Laine L et al (eds). Textbook of gastroenterology. Philadelphia: Lippincott Williams and Wilkins 2003: 2147-2165.
    • (2003) Textbook of Gastroenterology , pp. 2147-2165
    • Whitcomb, D.C.1
  • 51
    • 0035554033 scopus 로고    scopus 로고
    • Genetic testing for hereditary pancreatitis: Guideliness for indications, councelling, consent and privacy issues
    • Ellis I, Lerch MM, Whitcomb DC et al. Genetic testing for hereditary pancreatitis: Guideliness for indications, councelling, consent and privacy issues. Pancreatology 2001; 1: 401-411.
    • (2001) Pancreatology , vol.1 , pp. 401-411
    • Ellis, I.1    Lerch, M.M.2    Whitcomb, D.C.3
  • 52
    • 0034940538 scopus 로고    scopus 로고
    • Cigarette smoking a risk factors for pancreatic cancer in patients with hereditary pancreatitis
    • Lowenfels AB, Maisonneuve P, Withcomb DC et al. Cigarette smoking a risk factors for pancreatic cancer in patients with hereditary pancreatitis. JAMA 2001; 286: 169-170.
    • (2001) JAMA , vol.286 , pp. 169-170
    • Lowenfels, A.B.1    Maisonneuve, P.2    Withcomb, D.C.3
  • 53
    • 33947444147 scopus 로고
    • Isolation of a crystaline trypsin inhibitor-anticoagulant protein from the pancreas
    • Kazal LA, Spicer DS, Brahinsky RA. Isolation of a crystaline trypsin inhibitor-anticoagulant protein from the pancreas. J Am Chem Soc 1948; 70: 304-340.
    • (1948) J Am Chem Soc , vol.70 , pp. 304-340
    • Kazal, L.A.1    Spicer, D.S.2    Brahinsky, R.A.3
  • 54
    • 0023594933 scopus 로고
    • Primary structure of human pancreatic secretory trypsinogen inhibitor (PSTI) gene
    • Horii A, Kobayashi T, Tomita N et al. Primary structure of human pancreatic secretory trypsinogen inhibitor (PSTI) gene. Biochem Biophys Res Commun 1987; 149: 635-641.
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 635-641
    • Horii, A.1    Kobayashi, T.2    Tomita, N.3
  • 55
    • 0017335059 scopus 로고
    • The primary structure of the human pancreatic secretory trypsin inhibitor. Amino acid sequence of the reduced S-aminoethylated protein
    • Bartelt DC, Shapanka R, Greene U. The primary structure of the human pancreatic secretory trypsin inhibitor. Amino acid sequence of the reduced S-aminoethylated protein. Arch Biochem Biophys 1977; 179: 189-199.
    • (1977) Arch Biochem Biophys , vol.179 , pp. 189-199
    • Bartelt, D.C.1    Shapanka, R.2    Greene, U.3
  • 56
    • 0001452297 scopus 로고
    • Temporary inhibition of trypsin
    • Laskowski M, Wu FC. Temporary inhibition of trypsin. J Biol Chem 1953; 204: 797-805.
    • (1953) J Biol Chem , vol.204 , pp. 797-805
    • Laskowski, M.1    Wu, F.C.2
  • 57
    • 0034039578 scopus 로고    scopus 로고
    • Mutations in the gene encoding the serine protease inhibitor Kazal type 1 are associated with chronic pancreatitis
    • Witt H, Luck W, Hennies HC et al. Mutations in the gene encoding the serine protease inhibitor Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000; 25: 213-216.
    • (2000) Nat Genet , vol.25 , pp. 213-216
    • Witt, H.1    Luck, W.2    Hennies, H.C.3
  • 58
    • 0033857452 scopus 로고    scopus 로고
    • SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis
    • Pfützer RH, Barmada NM, Brunskill APJ et al. SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology 2000; 119: 615-623.
    • (2000) Gastroenterology , vol.119 , pp. 615-623
    • Pfützer, R.H.1    Barmada, N.M.2    Brunskill, A.P.J.3
  • 59
    • 0036113792 scopus 로고    scopus 로고
    • Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis
    • Drenth JPH, Te Morsche R, Jansen JBMJ. Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis. Gut 2002; 50: 687-692.
    • (2002) Gut , vol.50 , pp. 687-692
    • Drenth, J.P.H.1    Te Morsche, R.2    Jansen, J.B.M.J.3
  • 60
    • 0034111551 scopus 로고    scopus 로고
    • Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic pancreatitis
    • Chen JM, Mercier B, Audrézet MP, Ferec C. Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic pancreatitis. J Med Genet 2000; 37: 67-69.
    • (2000) J Med Genet , vol.37 , pp. 67-69
    • Chen, J.M.1    Mercier, B.2    Audrézet, M.P.3    Ferec, C.4
  • 61
    • 0034787766 scopus 로고    scopus 로고
    • Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis
    • Kuwata K, Hirota M, Sugita H et al. Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis. J Gastroenterol 2001; 36: 612-618.
    • (2001) J Gastroenterol , vol.36 , pp. 612-618
    • Kuwata, K.1    Hirota, M.2    Sugita, H.3
  • 62
    • 0035816020 scopus 로고    scopus 로고
    • Mutation in the SPINK 1 trypsin inhibitor gene, alcohol use and chronic pancreatitis
    • Witt H, Luck W, Becher M et al. Mutation in the SPINK 1 trypsin inhibitor gene, alcohol use and chronic pancreatitis. JAMA 2001; 285: 2716-2717.
    • (2001) JAMA , vol.285 , pp. 2716-2717
    • Witt, H.1    Luck, W.2    Becher, M.3
  • 63
    • 0036789204 scopus 로고    scopus 로고
    • SPINK 1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh
    • Schneider A, Susman A, Rossi L et al. SPINK 1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh. Gastroenterology 2002; 123: 1026-1030.
    • (2002) Gastroenterology , vol.123 , pp. 1026-1030
    • Schneider, A.1    Susman, A.2    Rossi, L.3
  • 64
    • 19044400563 scopus 로고    scopus 로고
    • SPINK 1 is a susceptibility gene for fibrocalculous pancreactic diabetes in subjects from the Indian subcontinent
    • Hassan Z, Mohan V, Ali L et al. SPINK 1 is a susceptibility gene for fibrocalculous pancreactic diabetes in subjects from the Indian subcontinent. Am J Hum Genet 2002; 71: 964-968.
    • (2002) Am J Hum Genet , vol.71 , pp. 964-968
    • Hassan, Z.1    Mohan, V.2    Ali, L.3
  • 65
    • 0036250761 scopus 로고    scopus 로고
    • How to think about SPINK and pancreatitis
    • Whitcomb DC. How to think about SPINK and pancreatitis. Am J Gastroenterol 2002; 97: 1085-1088.
    • (2002) Am J Gastroenterol , vol.97 , pp. 1085-1088
    • Whitcomb, D.C.1
  • 66
    • 0035552239 scopus 로고    scopus 로고
    • SPINK1 mutations are associated with multiple phenotypes
    • Pfützer RH, Whitcomb DC. SPINK1 mutations are associated with multiple phenotypes. Pancreatology 2001; 1: 457-460.
    • (2001) Pancreatology , vol.1 , pp. 457-460
    • Pfützer, R.H.1    Whitcomb, D.C.2
  • 67
    • 2442657876 scopus 로고    scopus 로고
    • A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK 1 mutations
    • Felderbauer P, Hoffmann P, Einwachter H et al. A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK 1 mutations. BMC Gastroenterol 2003; 3: 34.
    • (2003) BMC Gastroenterol , vol.3 , pp. 34
    • Felderbauer, P.1    Hoffmann, P.2    Einwachter, H.3
  • 68
    • 0025760318 scopus 로고    scopus 로고
    • Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator CFTR/gene
    • 199
    • Zielinski J, Rozmahel R, Bozon D et al. Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator CFTR/gene. Genomics 199; 10: 214-228.
    • Genomics , vol.10 , pp. 214-228
    • Zielinski, J.1    Rozmahel, R.2    Bozon, D.3
  • 69
    • 0027481813 scopus 로고
    • The cystic fibrosis transmembrane conductance regulator
    • Riordan JR. The cystic fibrosis transmembrane conductance regulator. Annu Rev Physiol 1993; 55: 609-630.
    • (1993) Annu Rev Physiol , vol.55 , pp. 609-630
    • Riordan, J.R.1
  • 70
    • 0032912589 scopus 로고    scopus 로고
    • Structure and function of the CFTR chloride channel
    • Sheppard DN; Welsh MJ. Structure and function of the CFTR chloride channel. Physiol Rev 1999; 79: S23-S45.
    • (1999) Physiol Rev , vol.79
    • Sheppard, D.N.1    Welsh, M.J.2
  • 71
    • 0027162649 scopus 로고
    • Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
    • Welsh M, Smith A. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 1993; 73: 1251-1254.
    • (1993) Cell , vol.73 , pp. 1251-1254
    • Welsh, M.1    Smith, A.2
  • 72
    • 0028860909 scopus 로고
    • Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations
    • Wilschanski M, Zielenski J, Markiewicz D et al. Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations. J Pediatr 1995; 127: 705-710.
    • (1995) J Pediatr , vol.127 , pp. 705-710
    • Wilschanski, M.1    Zielenski, J.2    Markiewicz, D.3
  • 73
    • 0034089406 scopus 로고    scopus 로고
    • Genotype-phenotype relationships in cystic fibrosis
    • Mickle JE, Cutting GR. Genotype-phenotype relationships in cystic fibrosis. Med Clin North Am 2000; 84: 597-607.
    • (2000) Med Clin North Am , vol.84 , pp. 597-607
    • Mickle, J.E.1    Cutting, G.R.2
  • 74
    • 0032480253 scopus 로고    scopus 로고
    • Mutations of the cystic fibrosis gene in patients with chronic pancreatitis
    • Sharer N, Schwarz M, Malone G et al. Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 1998; 339: 645-652.
    • (1998) N Engl J Med , vol.339 , pp. 645-652
    • Sharer, N.1    Schwarz, M.2    Malone, G.3
  • 75
    • 0032480346 scopus 로고    scopus 로고
    • Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis
    • Cohn JA, Friedman KJ, Noonc PG et al. Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 1998; 339: 653-658.
    • (1998) N Engl J Med , vol.339 , pp. 653-658
    • Cohn, J.A.1    Friedman, K.J.2    Noonc, P.G.3
  • 76
    • 0033899522 scopus 로고    scopus 로고
    • Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis
    • Ockenga J, Stuhrmann M, Ballman M et al. Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis. Am J Gastroenterol 2000; 95: 2061-2067.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2061-2067
    • Ockenga, J.1    Stuhrmann, M.2    Ballman, M.3
  • 77
    • 0029616734 scopus 로고
    • Cystic fibrosis: Genotypic and phenotypic variations
    • Zielinski J, Tsui LC. Cystic fibrosis: genotypic and phenotypic variations. Annu Rev Genet 1995; 29: 777-807.
    • (1995) Annu Rev Genet , vol.29 , pp. 777-807
    • Zielinski, J.1    Tsui, L.C.2
  • 78
    • 0035213536 scopus 로고    scopus 로고
    • Cystic fibrosis gene mutations and pancreatitis risk: Relation to epithelial ion transport and trypsin inhibitor gene mutations
    • Noone P, Zhou Z, Silverman LM et al. Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. Gastroenterology 2001; 121: 1310-1319.
    • (2001) Gastroenterology , vol.121 , pp. 1310-1319
    • Noone, P.1    Zhou, Z.2    Silverman, L.M.3
  • 79
    • 0034039048 scopus 로고    scopus 로고
    • Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis
    • Cohn JA, Bornstein JD, Jowell PS. Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis. Med Clin North Am 2000; 84: 621-631.
    • (2000) Med Clin North Am , vol.84 , pp. 621-631
    • Cohn, J.A.1    Bornstein, J.D.2    Jowell, P.S.3
  • 80
    • 85047700382 scopus 로고    scopus 로고
    • Determination of the relative contribution of three genes - The cystic fibrosis transmembrane conductance regulatory gene, the cationic trypsinogen gene and the pancreatic secretory trypsin inhibitory gene - To the etiology of idiopathic chronic pancreatitis
    • Andrézet MP, Chen JM, Le Maréchal L et al. Determination of the relative contribution of three genes - the cystic fibrosis transmembrane conductance regulatory gene, the cationic trypsinogen gene and the pancreatic secretory trypsin inhibitory gene - to the etiology of idiopathic chronic pancreatitis. Eur J Hum Genet 2002; 10: 100-106.
    • (2002) Eur J Hum Genet , vol.10 , pp. 100-106
    • Andrézet, M.P.1    Chen, J.M.2    Le Maréchal, L.3
  • 81
    • 0037228287 scopus 로고    scopus 로고
    • Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatitis conditions: Arguments for motion
    • Whitcomb DC. Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatitis conditions: Arguments for motion. Can J Gastroenterol 2003; 17: 47-52.
    • (2003) Can J Gastroenterol , vol.17 , pp. 47-52
    • Whitcomb, D.C.1
  • 82
    • 0037224076 scopus 로고    scopus 로고
    • Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: Arguments against the motion
    • Cohn JA. Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: Arguments against the motion. Can J Gastroenterol 2003; 17: 53-55.
    • (2003) Can J Gastroenterol , vol.17 , pp. 53-55
    • Cohn, J.A.1
  • 83
    • 0038281512 scopus 로고    scopus 로고
    • UDP Glucuronosyltransferase (UGT1A7) gene polymorphysms increase the risk of chronic pancreatitis and pancreatic cancer
    • Ockenga J, Vogel A, Teich N et al. UDP Glucuronosyltransferase (UGT1A7) gene polymorphysms increase the risk of chronic pancreatitis and pancreatic cancer. Gastroenterology 2003; 124: 1802-1808.
    • (2003) Gastroenterology , vol.124 , pp. 1802-1808
    • Ockenga, J.1    Vogel, A.2    Teich, N.3
  • 85
    • 0036223994 scopus 로고    scopus 로고
    • Polymorphism in alcohol - Metabolizing enzymes, glutathion-S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis
    • Frenzer A, Butler WJ, Norton ID et al. Polymorphism in alcohol - metabolizing enzymes, glutathion-S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis. J Gastroenterol Hepatol 2002; 17: 177-182.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 177-182
    • Frenzer, A.1    Butler, W.J.2    Norton, I.D.3
  • 86
    • 18344414252 scopus 로고    scopus 로고
    • Genotypes of alcohol - Metabolizing enzymes in relation to alcoholic chronic pancreatitis in Japan
    • Maruyama K, Takahashi H, Matsushita S et al. Genotypes of alcohol - metabolizing enzymes in relation to alcoholic chronic pancreatitis in Japan. Alcohol Clin Exp Res 1999; 23 (suppl 4): 85S-91S.
    • (1999) Alcohol Clin Exp Res , vol.23 , Issue.SUPPL. 4
    • Maruyama, K.1    Takahashi, H.2    Matsushita, S.3
  • 87
    • 0035040258 scopus 로고    scopus 로고
    • Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
    • Yang B, O'Reilly DA, Demaine AG et al. Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis. Alcohol 2001; 23: 91-97.
    • (2001) Alcohol , vol.23 , pp. 91-97
    • Yang, B.1    O'Reilly, D.A.2    Demaine, A.G.3
  • 88
    • 0041321170 scopus 로고    scopus 로고
    • Glutathione S-transferase null genotype afford protection against alcohol induced chronic pancreatitis
    • Verlaan M, Te Morsche RH, Roelafs HM et al. Glutathione S-transferase null genotype afford protection against alcohol induced chronic pancreatitis. Am J Med Genet 2003; 1: 34-39.
    • (2003) Am J Med Genet , vol.1 , pp. 34-39
    • Verlaan, M.1    Te Morsche, R.H.2    Roelafs, H.M.3
  • 89
    • 0036282292 scopus 로고    scopus 로고
    • Pancreatic, stellate cell respond to inflammatory cytokines: Potential role in chronic pancreatitis
    • Mews P, Phillias P, Fahmy R et al. Pancreatic, stellate cell respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002; 50: 535-541.
    • (2002) Gut , vol.50 , pp. 535-541
    • Mews, P.1    Phillias, P.2    Fahmy, R.3
  • 90
    • 0842288114 scopus 로고    scopus 로고
    • Analysis of tumour necrosis factor alpha and interleukin 10 promotor variants in patients with chronic pancreatitis
    • Beranek H, Teich N, Witt H et al. Analysis of tumour necrosis factor alpha and interleukin 10 promotor variants in patients with chronic pancreatitis. Eur J Gastroenterol Hepatol 2003; 15: 1223-1227.
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 1223-1227
    • Beranek, H.1    Teich, N.2    Witt, H.3
  • 91
    • 1842585744 scopus 로고    scopus 로고
    • Analysis of tumour necrosis factor-alpha, transforming growth factor-beta 1, interleukin-10 and interferon-gamma polymorphisms in patients with alcoholic pancreatitis
    • Schneider A, Barmada MM, Slivka A et al. Analysis of tumour necrosis factor-alpha, transforming growth factor-beta 1, interleukin-10 and interferon-gamma polymorphisms in patients with alcoholic pancreatitis. Alcohol 2004; 32: 19-24.
    • (2004) Alcohol , vol.32 , pp. 19-24
    • Schneider, A.1    Barmada, M.M.2    Slivka, A.3
  • 92
    • 0036597492 scopus 로고    scopus 로고
    • Hereditary pancreatitis: A model for inflammatory diseases of the pancreas
    • Schneider A, Whitcomb DC. Hereditary pancreatitis: a model for inflammatory diseases of the pancreas. Best Pract Res Clin Gastroenterol 2002; 16: 347-363.
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , pp. 347-363
    • Schneider, A.1    Whitcomb, D.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.