Genotypes of alcohol-metabolizing enzymes in relation to alcoholic chronic pancreatitis in Japan

Alcoholism: Clinical and Experimental Research

Volumn 23, Issue 4 SUPPL., 1999, Pages

  Maruyama, Katsuya ^a   Takahashi, Hisao ^a   Matsushita, Sachio ^a   Nakano, Masayuki ^b   Harada, Hideo ^c   Otsuki, Makoto ^d   Ogawa, Michio ^e   Suda, Kouichi ^f   Baba, Tadao ^g   Honma, Tatsuji ^h   Moroboshi, Toshio ⁱ   Matsuno, Masaki ^j  

^a KURIHAMA NATIONAL HOSPITAL   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^e KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^f JUNTENDO UNIVERSITY   (Japan)

^g SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^h SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^j TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

Alcohol Dehydrogenase; Alcohol Metabolizing Enzyme; Alcoholic pancreatitis; Genotype; Pancreatic Fibrosis

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CYTOCHROME P450; DNA;

ALCOHOLIC PANCREATITIS; ALLELE; CONFERENCE PAPER; CONTROLLED STUDY; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 18344414252     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1999.tb04541.x     Document Type: Conference Paper

References (22)

1. Bosron WF, Li T-K (1986) Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 6:502-510.
2. Crabb DW, Edenberg HJ, Bosron WF, Li T-K (1989) Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. J Clin Invest 83:314-316.
3. Day CP, Bashir R, James OFW, Bassendine MF, Crabb DW, Thomasson HR, Li T-K, Edenberg HJ (1991) Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage. Hepatology 14: 798-801.
4. Dreiling DA, Koller M (1985) The natural history of alcoholic pancreatitis: Update 1985. Mt Sinai J Med 52:340-342.
5. Dumas F, Coutelle C, Gerolami A, Groppi A, Cassaigne A, Couzigou P (1995) Role of alcohol dehydrogenase polymorphism in alcoholic patients with chronic pancreatitis. Gastroenterology 104:A302.
6. Ehrig T, Bosron WF, Li T-K (1990) Alcohol and aldehyde dehydrogenase. Alcohol Alcohol 25:105-116.
7. Enomoto N, Takase S, Takada N, Tadaka A (1991) Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes. Hepatology 13:1071-1075.
8. Haber P, Wilson J, Apte M, Pirola R (1995) Individual susceptibility to alcoholic pancreatitis: Still an enigma. J Lab Clin Med 125:305-312.
9. Harada S, Misawa S, Agarwal DP, Goedde HW (1980) Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: Isoenzyme variation and its possible role in alcohol intoxication. Am J Hum Genet 32:8-15.
10. Hayashi S, Watanabe J, Kawajiri K (1991) Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P4502E1 gene. J Biochem 110:559-565.
11. Higuchi S, Matsushita S, Murayama M, Takagi S, Hayashida M (1995) Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism. Am J Psychiatry 152:1219-1221.
12. Honma T, Harada H, Koizumi M (1997) Diagnostic criteria for chronic pancreatitis by the Japan Pancreas Society. Pancreas 15:14-15.
13. Matsumoto M, Takahashi H, Maruyama K, Higuchi S, Matsushita S, Muramatsu T, Okuyama K, Yokoyama A, Nakano M, Ishii H (1996) Genotypes of alcohol-metabolizing enzymes and the risk for alcoholic chronic pancreatitis in Japanese alcoholics. Alcohol Clin Exp Res 20: 289A-292A.
14. Norton ID, Apte M, Haber P, Pisola RC, McCaughan GW, Wilson JS (1996) Cytochrome P4502E is present in rat pancreas and induced by chronic ethanol administration. Gastroenterology 110:A1280.
15. 1) with the disease. Am J Hum Genet 43:744-748.
16. Suda K, Mogaki M, Oyama T, Matsumoto Y (1990) Histopathologic and immunohistochemical studies on alcoholic pancreatitis and chronic obstructive pancreatitis: Special emphasis on ductal obstruction and genesis of pancreatitis. Am J Gastroenterol 85:271-276.
17. Thomasson HR, Edenberg HJ, Crabb DW, Mai XL, Jerome RE, Li T-K, Wang SP, Lin YT, Lu RB, Yin SJ (1991) Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 48:677-681.
18. Tsutsumi M, Wong J-S, Takase S, Takada A (1994) Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Alcohol Alcohol 29:29-32.
19. Yamauchi M (1998) Association of polymorphism in the alcohol dehydrogenase 2 gene with alcohol-related organ injuries, especially liver cirrhosis. Addict Biol 3:151-157.
20. Yamauchi M, Maezawa Y, Mizuhara Y, Ohata M, Hirakawa J, Nakajima H, Toda G (1995) Polymorphisms in alcohol metabolizing enzyme genes and alcoholic cirrhosis in Japanese patients: A multivariate analysis. Hepatology 22:1136-1142.
21. Yokoyama H, Boraona E, Lieber CS (1995) Upstream structure of human ADH7 gene and organ distribution of its expression. Biochem Biophys Res Commun 206:216-222.
22. Xu Y, Carr LG, Bosron WF, Li T-K, Edenberg HJ (1988) Genotyping of human alcohol dehydrogenase at the ADH2 and ADH3 loci following DNA sequence amplification. Genomics 2:209-214.