Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-α receptor levels in humans with relative leptin deficiency

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 3, 2005, Pages 1625-1631

  Chan, Jean L ^a   Moschos, Stergios J ^a   Bullen, John ^a   Heist, Kathleen ^a   Li, Xian ^a   Kim, Young Bum ^a   Kahn, Barbara B ^a   Mantzoros, Christos S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; RECOMBINANT LEPTIN; TUMOR NECROSIS FACTOR RECEPTOR; DNA BINDING PROTEIN; DRUG DERIVATIVE; LEPTIN; MILK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; RECOMBINANT METHIONYL HUMAN LEPTIN; STAT1 PROTEIN; STAT1 PROTEIN, HUMAN; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL ACTIVATION; CELL POPULATION; CIRCULATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; ENERGY TRANSFER; GENETIC TRANSCRIPTION; HELPER CELL; HORMONE DEFICIENCY; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; LEPTIN DEFICIENCY; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; BLOOD; DRUG EFFECT; FEMALE; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ADULT; CYTOKINES; DNA-BINDING PROTEINS; FEMALE; HUMANS; LEPTIN; MALE; MILK PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, HELPER-INDUCER; TRANS-ACTIVATORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 15944384648     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-1823     Document Type: Article

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