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Journal of Pharmaceutical and Biomedical Analysis

Volumn 37, Issue 4, 2005, Pages 739-749

A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes

(4) Bhoopathy, S a Xin, B b Unger, S E b Karnes, H T a

a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE (United States)

b DUPONT COMPANY (United States)

Author keywords

CYP 3A4; Dextromethorphan; In vitro metabolism; LC MS MS

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; MIDAZOLAM;

ANIMAL CELL; ARTICLE; AUTOMATION; CONTROLLED STUDY; DRUG METABOLISM; DRUG POTENCY; DRUG SCREENING; ELECTROSPRAY; EVALUATION; HEATING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TEMPERATURE MEASUREMENT;

EID: 15744392933 PISSN: 07317085 EISSN: None Source Type: Journal
DOI: 10.1016/j.jpba.2004.08.043 Document Type: Article

Times cited : (20)

References (30)

1
- 0342941483
- U.A. Meyer J. Pharmacokinet. Biopharm. 24 1996 446 459
- (1996) J. Pharmacokinet. Biopharm. , vol.24 , pp. 446-459
- Meyer, U.A.¹

2
- 0028114740
- A.D. Rodrigues Biochem. Pharmacol. 48 1994 2147 2156
- (1994) Biochem. Pharmacol. , vol.48 , pp. 2147-2156
- Rodrigues, A.D.¹

3
- 0031570357
- C.L. Crespi, V.P. Miller, and B.W. Penman Anal. Biochem. 248 1997 188 190
- (1997) Anal. Biochem. , vol.248 , pp. 188-190
- Crespi, C.L.¹ Miller, V.P.² Penman, B.W.³

4
- 0033572466
- N. Chauret, N. Tremblay, R.L. Lackman, J. Gauthier, J.M. Silva, J. Morris, J.A. Yergey, and D.A. Nicoll-Griffith Anal. Biochem. 276 1999 215 226
- (1999) Anal. Biochem. , vol.276 , pp. 215-226
- Chauret, N.¹ Tremblay, N.² Lackman, R.L.³ Gauthier, J.⁴ Silva, J.M.⁵ Morris, J.⁶ Yergey, J.A.⁷ Nicoll-Griffith, D.A.⁸

5
- 0032970480
- G.C. Moody, S.J. Griffin, A.N. Mather, D.F. McGinnity, and R.J. Riley Xenobiotica 29 1999 53 75
- (1999) Xenobiotica , vol.29 , pp. 53-75
- Moody, G.C.¹ Griffin, S.J.² Mather, A.N.³ McGinnity, D.F.⁴ Riley, R.J.⁵

6
- 0033997634
- H. Yin, J. Racha, S.Y. Li, N. Olejnik, H. Satoh, and D. Moore Xenobiotica 30 2000 141 154
- (2000) Xenobiotica , vol.30 , pp. 141-154
- Yin, H.¹ Racha, J.² Li, S.Y.³ Olejnik, N.⁴ Satoh, H.⁵ Moore, D.⁶

7
- 0031152073
- J.J. Burbaum, and N.H. Sigal Curr. Opin. Chem. Biol. 1 1997 72 78
- (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 72-78
- Burbaum, J.J.¹ Sigal, N.H.²

8
- 0029072923
- E. Gelpi J. Chromatogr. A 703 1995 59 80
- (1995) J. Chromatogr. a , vol.703 , pp. 59-80
- Gelpi, E.¹

9
- 0031913816
- R.B. Van Breemen, D. Nikolic, and J.L. Bolton Drug Metabol. Disposit. 26 1998 85 90
- (1998) Drug Metabol. Disposit. , vol.26 , pp. 85-90
- Van Breemen, R.B.¹ Nikolic, D.² Bolton, J.L.³

10
- 0041918439
- C.L. Fernandez-Metzler, K.G. Owens, T.A. Baillie, and R.C. King Drug Metabol. Disposit. 27 1999 32 40
- (1999) Drug Metabol. Disposit. , vol.27 , pp. 32-40
- Fernandez-Metzler, C.L.¹ Owens, K.G.² Baillie, T.A.³ King, R.C.⁴

11
- 0031939705
- J. Ayrton, R. Plumb, W.J. Leavens, D. Mallett, M. Dickins, and G.J. Dear Rapid Commun. Mass Spectr. 12 1998 217 224
- (1998) Rapid Commun. Mass Spectr. , vol.12 , pp. 217-224
- Ayrton, J.¹ Plumb, R.² Leavens, W.J.³ Mallett, D.⁴ Dickins, M.⁵ Dear, G.J.⁶

12
- 0033811314
- H. Bu, L. Magis, K. Knuth, and P. Teitelbaum Rapid Commun. Mass Spectr. 14 2000 1619 1624
- (2000) Rapid Commun. Mass Spectr. , vol.14 , pp. 1619-1624
- Bu, H.¹ Magis, L.² Knuth, K.³ Teitelbaum, P.⁴

13
- 0033833016
- D.L. McCauley-Myers, T.H. Eichhold, R.E. Bailey, D.J. Dobrozsi, K.J. Best, J.W. Hayes II, and S.H. Hohe II J. Pharmaceut. Biomed. Anal. 23 2000 825 835
- (2000) J. Pharmaceut. Biomed. Anal. , vol.23 , pp. 825-835
- McCauley-Myers, D.L.¹ Eichhold, T.H.² Bailey, R.E.³ Dobrozsi, D.J.⁴ Best, K.J.⁵ Hayes II, J.W.⁶ Hohe II, S.H.⁷

14
- 0031466149
- R.S. Obach Drug Metabol. Disposit. 25 1997 1359 1369
- (1997) Drug Metabol. Disposit. , vol.25 , pp. 1359-1369
- Obach, R.S.¹

15
- 0032733974
- R.S. Obach Drug Metabol. Disposit. 27 1999 1350 1359
- (1999) Drug Metabol. Disposit. , vol.27 , pp. 1350-1359
- Obach, R.S.¹

16
- 0029965231
- J. Ducharme, S. Abdullah, and I.W. Wainer J. Chromatogr. B 678 1996 113 128
- (1996) J. Chromatogr. B , vol.678 , pp. 113-128
- Ducharme, J.¹ Abdullah, S.² Wainer, I.W.³

17
- 0024373348
- T. Kronbach, D. Mathys, M. Umeno, F.J. Gonzalez, and U.A. Meyer Mol. Pharmacol. 36 1989 89 96
- (1989) Mol. Pharmacol. , vol.36 , pp. 89-96
- Kronbach, T.¹ Mathys, D.² Umeno, M.³ Gonzalez, F.J.⁴ Meyer, U.A.⁵

18
- 0029790347
- A. Ghosal, H. Satoh, E. Bush, P.E. Thomas, and D. Moore Drug Metabol. Disposit. 24 1996 940 947
- (1996) Drug Metabol. Disposit. , vol.24 , pp. 940-947
- Ghosal, A.¹ Satoh, H.² Bush, E.³ Thomas, P.E.⁴ Moore, D.⁵

19
- 0003626532
- Pergamon Press New York
- U.A. Meyer, R.C. Skoda, U.M. Zanger, M. Heim, and F. Broly Pharmacogenetics of Drug Metabolism 1992 Pergamon Press New York pp. 609-623
- (1992) Pharmacogenetics of Drug Metabolism
- Meyer, U.A.¹ Skoda, R.C.² Zanger, U.M.³ Heim, M.⁴ Broly, F.⁵

20
- 0030428256
- G. Wilkinson J. Pharmacokinet. Biopharm. 24 1996 475 490
- (1996) J. Pharmacokinet. Biopharm. , vol.24 , pp. 475-490
- Wilkinson, G.¹

21
- 0034013033
- Y. Sai, R. Dai, T.J. yang, K.W. Krausz, F.J. Gonzalzez, H.V. Gelboin, and M. Shous Xenobiotica 30 2000 327 343
- (2000) Xenobiotica , vol.30 , pp. 327-343
- Sai, Y.¹ Dai, R.² Yang, T.J.³ Krausz, K.W.⁴ Gonzalzez, F.J.⁵ Gelboin, H.V.⁶ Shous, M.⁷

22
- 0029050135
- M.S. Ching, C.L. Blake, H. Ghabrial, S.W. Ellis, M.S. Lennard, G.T. Tucker, and R.A. Smallwood Biochem. Pharmacol. 50 1995 833 837
- (1995) Biochem. Pharmacol. , vol.50 , pp. 833-837
- Ching, M.S.¹ Blake, C.L.² Ghabrial, H.³ Ellis, S.W.⁴ Lennard, M.S.⁵ Tucker, G.T.⁶ Smallwood, R.A.⁷

23
- 0032870729
- J. Shin, N. Soukhova, and D.A. Flockhart Drug Metabol. Disposit. 27 1999 1078 1084
- (1999) Drug Metabol. Disposit. , vol.27 , pp. 1078-1084
- Shin, J.¹ Soukhova, N.² Flockhart, D.A.³

24
- 0028925906
- C.M. Masimirembwa, J.A. Hasler, and I. Johansson Eur. J. Clin. Pharmacol. 48 1995 35 38
- (1995) Eur. J. Clin. Pharmacol. , vol.48 , pp. 35-38
- Masimirembwa, C.M.¹ Hasler, J.A.² Johansson, I.³

25
- 0028342648
- J.B. Houston Biochem. Pharmacol. 47 1994 1469 1474
- (1994) Biochem. Pharmacol. , vol.47 , pp. 1469-1474
- Houston, J.B.¹

26
- 0033028843
- S.M. Abdel-Rehman, K. Marcuci, T. Boge, R. Russell, G.L. Kearns, and J. Steven Leeder Drug Metabol. Disposit. 27 1999 770 775
- (1999) Drug Metabol. Disposit. , vol.27 , pp. 770-775
- Abdel-Rehman, S.M.¹ Marcuci, K.² Boge, T.³ Russell, R.⁴ Kearns, G.L.⁵ Steven Leeder, J.⁶

27
- 0027499806
- N.L. Kerry, A.A. Somogyi, G. Mikus, and F. Bochner Biochem. Pharmacol. 45 1993 833 839
- (1993) Biochem. Pharmacol. , vol.45 , pp. 833-839
- Kerry, N.L.¹ Somogyi, A.A.² Mikus, G.³ Bochner, F.⁴

28
- 0032968065
- L.E. Witherow, and J.B. Houston J. Pharmacol. Exp. Therapeut. 290 1999 58 65
- (1999) J. Pharmacol. Exp. Therapeut. , vol.290 , pp. 58-65
- Witherow, L.E.¹ Houston, J.B.²

29
- 0035987898
- R.S. Obach, and A.E. Reed-Hagen Drug Metabol. Disposit. 30 2002 831 837
- (2002) Drug Metabol. Disposit. , vol.30 , pp. 831-837
- Obach, R.S.¹ Reed-Hagen, A.E.²

30
- 0031445547
- M.F. Paine, M. Khalighi, J.M. Fisher, D.D. Shen, K.L. Kunze, C.L. Marsh, J.D. Perkins, and K.E. Thummel J. Pharmacol. Exp. Therapeut. 283 1997 1552 1562
- (1997) J. Pharmacol. Exp. Therapeut. , vol.283 , pp. 1552-1562
- Paine, M.F.¹ Khalighi, M.² Fisher, J.M.³ Shen, D.D.⁴ Kunze, K.L.⁵ Marsh, C.L.⁶ Perkins, J.D.⁷ Thummel, K.E.⁸

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