Antiviral therapy of congenital cytomegalovirus infection

Seminars in Pediatric Infectious Diseases

Volumn 16, Issue 1 SPEC.ISS., 2005, Pages 50-59

  Schleiss, Mark R ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BENZIMIDAVIR; BENZIMIDAZOLE DERIVATIVE; CIDOFOVIR; CYTOMEGALOVIRUS ANTIBODY; FOSCARNET; FOSCARNET SODIUM; GANCICLOVIR; GW 1263W94; GW 275175X; HEXADECYLOXYPROPYLCIDOFOVIR; LEFLUNOMIDE; LIVE VACCINE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NUCLEOSIDE ANALOG; OCTADECYLOXYETHYLCIDOFOVIR; TOMEGLOVIR; UNCLASSIFIED DRUG; VALGANCICLOVIR; IMMUNOGLOBULIN;

AGE DISTRIBUTION; ANAPHYLAXIS; ANEMIA; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CLINICAL TRIAL; CONGENITAL INFECTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISABILITY; DISEASE TRANSMISSION; DRUG INDICATION; DRUG MECHANISM; ECONOMIC ASPECT; EPIDEMIOLOGICAL DATA; GRANULOCYTOPENIA; HUMAN; HUMAN CYTOMEGALOVIRUS; LICENSING; METABOLIC ACIDOSIS; NEPHROTOXICITY; NEUTROPENIA; NEWBORN SCREENING; NONHUMAN; PERCEPTION DEAFNESS; PERINATAL INFECTION; PERINATAL PERIOD; PREVALENCE; REVIEW; THROMBOCYTOPENIA; VIRUS INFECTIVITY; VIRUS TRANSMISSION; CYTOMEGALIC INCLUSION BODY DISEASE; NEWBORN;

ANTIVIRAL AGENTS; CYTOMEGALOVIRUS INFECTIONS; HUMANS; IMMUNOGLOBULINS; INFANT, NEWBORN;

EID: 15744385123     PISSN: 10451870     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.spid.2004.09.012     Document Type: Article

References (95)

1. H. Ribbert Uber protozoenartigen Zellen in der Nireeines syphilitischen Neugeboren und in der Parotis von Kindern Zentralbl Allg Pathol 15 1904 945 948
2. M.G. Smith Propagation in tissue cultures of a cytopathogenic virus from human salivary gland virus (SGV) disease Proc Soc Exp Biol Med 92 1956 424 430
3. W.P. Rowe, J.W. Hartley, S. Waterman Cytopathogenic agent resembling salivary gland virus recovered from tissue cultures of human adenoids Proc Soc Exp Biol Med 92 1956 418 424
4. T.H. Weller, J.C. Macauley, J.M. Craig Isolation of intranuclear inclusion producing agents from infants with illnesses resembling cytomegalic inclusion disease Proc Soc Exp Biol Med 94 1957 4 12
5. Weller TH: The cytomegaloviruses ubiquitous agents with protean clinical manifestations. I. N Engl J Med 1971;285:203-14, and II. N Engl J Med 1971;285:267-74
6. Weller TH: The cytomegaloviruses ubiquitous agents with protean clinical manifestations. I. N Engl J Med 1971;285:203-14, and II. N Engl J Med 1971;285:267-74
7. E.S. Mocarski Jr, C.T. Courcelle Cytomegaloviruses and their replication D.M. Knipe P.M. Howley D.E. Griffin R.A. Lamb M.A. Martin B. Roizman S.E. Straus Fields Virology 2001 Lippincott Williams & Wilkins Philadelphia 2629 2673
8. A. Alcami, U.H. Koszinowski Viral mechanisms of immune evasion Trends Microbiol 8 2000 410 418
9. E.S. Mocarski Immunomodulation by cytomegaloviruses manipulative strategies beyond evasion Trends Microbiol 10 2000 332 339
10. C. Vink, M.J. Smit, R. Leurs, C.A. Bruggeman The role of cytomegalovirus-encoded homologs of G protein-coupled receptors and chemokines in manipulation of and evasion from the immune system J Clin Virol 23 2001 43 55
11. E.S. Mocarski Immune escape and exploitation strategies of cytomegaloviruses impact on and imitation of the major histocompatibility system Cellular Microbiol 6 2004 707 717
12. W.J. Britt, M. Mach Human cytomegalovirus glycoproteins Intervirology 39 1996 401 412
13. G.J. Demmler Congenital cytomegalovirus infection and disease Adv Pediatr Infect Dis 11 1996 135 162
14. P.D. Griffiths, C. Baboonian A prospective study of primary cytomegalovirus infection during pregnancy final report Br J Obstet Gynaecol 91 1984 307 315
15. Y.M. Sohn, M.K. Oh, K.B. Balcarek Cytomegalovirus infection in sexually active adolescents J Infect Dis 163 1991 460 463
16. Pass RF, Hutto C, Ricks R, Cloud GA: Increased rate of cytomegalovirus infection among parents of children attending day-care centers. N Engl J Med 314:1414-1418, 186
17. S.P. Adler Molecular epidemiology of cytomegalovirus evidence for viral transmission to parents from children infected at a day care center Pediatr Infect Dis 5 1986 315 3158
18. C.C. Balfour, H.H. Balfour Jr Cytomegalovirus is not an occupational risk for nurses in renal transplant and neonatal units. Results of a prospective surveillance study JAMA 256 1986 1909 1914
19. M.E. Dworsky, K. Welch, G. Cassady, S. Stagno Occupational risk for primary cytomegalovirus infection among pediatric health-care workers N Engl J Med 309 1983 950 953
20. S. Stagno, R.J. Whitley Herpesvirus infections of pregnancy. Part I. Cytomegalovirus and Epstein-Barr virus infections N Engl J Med 313 1985 1270 1274
21. K.B. Fowler, S. Stagno, R.F. Pass The outcome of congenital cytomegalovirus infection in relation to maternal antibody status N Engl J Med 326 1992 663 667
22. S.B. Boppana, L.B. Rivera, K.B. Fowler Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity N Engl J Med 344 2001 1366 1371
23. K. Ahlfors, S.A. Ivarsson, S. Harris Report on a long-term study of maternal and congenital cytomegalovirus infection in Sweden. Review of prospective studies available in the literature Scand J Infect Dis 31 1999 443 457
24. S.B. Boppana, K.B. Fowler, W.J. Britt Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus Pediatrics 104 1999 55 60
25. J.F. Bale, L. Miner, S.J. Petheram Congenital cytomegalovirus infection Curr Treat Options Neurol 4 2002 225 230
26. R.F. Pass, S. Stagno, G.J. Myers, C.A. Alford Outcome of symptomatic congenital cytomegalovirus infection results of long-term longitudinal follow-up Pediatrics 66 1980 758 762
27. K.B. Fowler, A.J. Dahle, S.B. Boppana, R.F. Pass Newborn hearing screening will children with hearing loss caused by congenital cytomegalovirus infection be missed? J Pediatr 135 1999 60 64
28. W.D. Williamson, G.J. Demmler, A.K. Percy, F.I. Catlin Progressive hearing loss in infants with asymptomatic congenital cytomegalovirus infection Pediatrics 90 1992 862 866
29. A.J. Dahle, K.B. Fowler, J.D. Wright Longitudinal investigation of hearing disorders in children with congenital cytomegalovirus J Am Acad Audiol 11 2000 283 290
30. S.P. Adler Neonatal cytomegalovirus infections due to blood Crit Rev Clin Lab Sci 23 1986 1 14
31. A.S. Yeager, F.C. Grumet, E.B. Hafleigh, A.M. Arvin, J.S. Bradley, C.G. Prober Prevention of transfusion-acquired cytomegalovirus infections in newborn infants J Pediatr 98 1981 281 287
32. J. Maschmann, K. Hamprecht, K. Dietz Cytomegalovirus infection of extremely low-birth weight infants via breast milk Clin Infect Dis 33 2001 1998 2003
33. B. Vollmer, K. Seibold-Weiger, C. Schmitz-Salue Postnatally acquired cytomegalovirus infection via breast milk effects on hearing and development in preterm infants Pediatr Infect Dis J 23 2004 322 327
34. W.G. Nichols, M. Boeckh Recent advances in the therapy and prevention of CMV infection J Clin Virol 16 2000 25 40
35. M.R. Schleiss Cytomegalovirus in immunocompromised persons Curr Treat Options Infect Dis 4 2002 43 50
36. D.W. Kimberlin Antiviral therapy for cytomegalovirus infections in pediatric patients Semin Pediatr Infect Dis 13 2002 22 30
37. P.D. Griffiths The 2001 Garrod lecture. The treatment of cytomegalovirus infection J Antimicrob Chemother 49 2002 243 253
38. E. De Clercq Antiviral drugs in current clinical use J Clin Virol 30 2004 115 133
39. V. Sullivan, C.L. Talarico, S.C. Stanat A protein kinase homolog controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells Nature 358 1992 162 164
40. E. Littler, A.D. Stuart, M.S. Chee Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir Nature 358 1992 160 162
41. M. Boeckh, G. Boivin Quantitation of cytomegalovirus methodologic aspects and clinical applications Clin Microbiol Rev 11 1998 533 554
42. A. Erice Resistance of human cytomegalovirus to antiviral drugs Clin Microbiol Rev 12 1999 286 297
43. S.C. Blackman, N.S. Lurain, D.P. Witte Emergence and compartmentalization of fatal multi-drug resistant cytomegalovirus (CMV) infection in a patient with autosomal-recessive severe combined immune deficiency (SCID) J Pediatr Hematol Oncol 26 2004 601 605
44. J.P. Lalezari, D.N. Friedberg, J. Bissett High dose oral ganciclovir treatment for cytomegalovirus retinitis J Clin Virol 24 2002 67 77
45. J.M. Cocohoba, I.R. McNicholl Valganciclovir an advance in cytomegalovirus therapeutics Ann Pharmacother 36 2002 1075 1079
46. F. Pereyra, R.H. Rubin Prevention and treatment of cytomegalovirus infection in solid organ transplant recipients Curr Opin Infect Dis 17 2004 357 361
47. M.R. Schleiss, M. McVoy Overview of congenitally and perinatally acquired cytomegalovirus infections recent advances in antiviral therapy Expert Rev Anti Infective Ther 2 2004 389 403
48. S. Chou, N.S. Lurain, K.D. Thompson Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus J Infect Dis 188 2003 32 39
49. D.R. Snydman, B.G. Werner, H.C. Meissner Use of cytomegalovirus immunoglobulin in multiply transfused premature neonates Pediatr Infect Dis J 14 1995 34 40
50. H. Negishi, H. Yamada, E. Hirayama Intraperitoneal administration of cytomegalovirus hyperimmunoglobulin to the cytomegalovirus-infected fetus J Perinatol 18 1998 466 469
51. S. Chou Antiviral drug resistance in human cytomegalovirus Transpl Infect Dis 1 1999 105 114
52. J. Neyts, E. De Clercq Mycophenolate mofetil strongly potentiates the anti-herpesvirus activity of acyclovir Antiviral Res 40 1998 53 56
53. J.R. Beadle, C. Hartline, K.A. Aldern Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro Antimicrob Agents Chemother 46 2002 2381 2386
54. D.J. Bidanset, J.R. Beadle, W.B. Wan Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infections J Infect Dis 190 2004 499 503
55. M.R. Underwood, R.J. Harvey, S.C. Stanat Inhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene product J Virol 72 1998 717 725
56. P.M. Krosky, M.R. Underwood, S.R. Turk Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames UL89 and UL56 J Virol 72 1998 4721 4728
57. R.J. Visalli, M. van Zeijl DNA encapsidation as a target for anti-herpesvirus drug therapy Antiviral Res 59 2 2003 73 87
58. K.K. Biron, R.J. Harvey, S.C. Chamberlain Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action Antimicrob Agents Chemother 46 2002 2365 2372
59. G.W. Koszalka, N.W. Johnson, S.S. Good Preclinical and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication Antimicrob Agents Chemother 46 2002 2373 2380
60. I. Buerger, J. Reefschlaeger, W. Bender A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products J Virol 75 2001 9077 9086
61. th ICAAC; 1999 Sep 26-29; San Francisco [abstract no. 945]
62. W.J. Waldman, D.A. Knight, L. Blinder Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide Intervirology 42 1999 412 418
63. S.A. Plotkin, H. Stetler Treatment of congenital cytomegalic inclusion disease with antiviral agents Antimicrobial Agents Chemother 9 1969 372 379
64. R.D. Feigin, P.G. Shackelford, M.W. Haymond, D.C. DeVivo Floxuridine treatment of congenital cytomegalic inclusion disease Pediatrics 48 1971 318 322
65. E.N. Kraybill, J.L. Sever, G.B. Avery, N. Movassaghi Experimental use of cytosine arabinoside in congenital cytomegalovirus infection J Pediatr 80 1972 485 487
66. G.H. McCracken Jr, J.P. Luby Cytosine arabinoside in the treatment of congenital cytomegalic inclusion disease J Pediatr 80 1972 488 493
67. J. Hocker, L.N. Cook, G. Adams, G. Rabalais Ganciclovir therapy of congenital cytomegalovirus pneumonia Pediatr Infect Dis J 9 1990 743 745
68. S.P. Attard-Montalto, M.C. English, L. Stimmler, G.J. Snodgrass Ganciclovir treatment of congenital cytomegalovirus infection a report of two cases Scand J Infect Dis 25 1993 385 388
69. M. Stronati, M.G. Revello, R.M. Cerbo Ganciclovir therapy of congenital human cytomegalovirus hepatitis Acta Paediatr 84 1995 340 341
70. J.G. Vallejo, J.A. Englund, J.A. Garcia-Prats, G.J. Demmler Ganciclovir treatment of steroid-associated cytomegalovirus disease in a congenitally infected neonate Pediatr Infect Dis J 13 1994 239 241
71. A. Junker, D. Matheson, A. Tingle, E. Thomas Immune responses after ganciclovir and immunoglobulin therapy of infants Pediatr Infect Dis J 10 1991 256 258
72. H. Reigstad, R. Bjerknes, T. Markestad, H. Myrmel Ganciclovir therapy of congenital cytomegalovirus disease Acta Paediatr 81 1992 707 708
73. M.G. Michaels, D.P. Greenberg, D.L. Sabo, E.R. Wald Treatment of children with congenital cytomegalovirus infection with ganciclovir Pediatr Infect Dis J 22 2003 504 509
74. G. Nigro, H. Scholz, U. Bartmann Ganciclovir therapy for symptomatic congenital cytomegalovirus infection in infants a two-regimen experience J Pediatr 124 1994 318 322
75. B. Crowley Ganciclovir treatment of symptomatic congenital cytomegalovirus infection J Antimicrob Chemother 50 2002 435 436
76. G. Nigro, A. Krzysztofiak, U. Bartmann Ganciclovir therapy for cytomegalovirus-associated liver disease in immunocompetent or immunocompromised children Arch Virol 142 1997 573 580
77. B. Fischler, T.H. Casswall, P. Malmborg, A. Nemeth Ganciclovir treatment in infants with cytomegalovirus infection and cholestasis J Pediatr Gastroenterol Nutr 34 2002 154 157
78. J.M. Trang, L. Kidd, W. Gruber NIAID Collaborative Antiviral Study Group Linear single-dose pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections Clin Pharmacol Ther 53 1993 15 21
79. X.J. Zhou, W. Gruber, G. Demmler NIAID Collaborative Antiviral Study Group Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections Antimicrob Agents Chemother 40 1996 2202 2205
80. R.J. Whitley, G. Cloud, W. Gruber NIAID Collaborative Antiviral Study Group Ganciclovir treatment of symptomatic congenital cytomegalovirus infection results of a phase II study J Infect Dis 175 1997 1080 1086
81. D.W. Kimberlin, C.Y. Lin, P.J. Sanchez Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system a randomized, controlled trial J Pediatr 143 2003 16 25
82. D. Zaknun, R. Zangerle, K. Kapelari Concurrent ganciclovir and foscarnet treatment for cytomegalovirus encephalitis and retinitis in an infant with acquired immunodeficiency syndrome case report and review Pediatr Infect Dis J 16 1997 807 811
83. E.M. Connor, R.S. Sperling, R. Gelber Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Groupz N Engl J Med 331 1994 1173 1180
84. G.I. Henderson, Z.Q. Hu, Y. Yang Ganciclovir transfer by human placenta and its effects on rat fetal cells Am J Med Sci 306 1993 151 156
85. L.C. Gilstrap, R.E. Bawdon, S.W. Roberts, S. Sobhi The transfer of the nucleoside analog ganciclovir across the perfused human placenta Am J Obstet Gynecol 170 1994 967 972
86. D.W. Kimberlin New antiviral therapeutic agents Semin Pediatr Infect Dis 12 2001 224 234
87. M.D. Pescovitz Absence of teratogenicity of oral ganciclovir used during early pregnancy in a liver transplant recipient Transplantation 67 1999 758 759
88. S.A. Laifer, G.D. Ehrlich, D.S. Huff Congenital cytomegalovirus infection in offspring of liver transplant recipients Clin Infect Dis 20 1995 52 55
89. M. Miguelez, A. Gonzalez, F. Perez Severe cytomegalovirus hepatitis in a pregnant woman treated with ganciclovir Scand J Infect Dis 30 1998 304 305
90. M.G. Revello, E. Percivalle, F. Baldanti Prenatal treatment of congenital human cytomegalovirus infection by fetal intravascular administration of ganciclovir Clin Diagn Virol 1 1993 61 67
91. R.C. Brady, M.R. Schleiss, D. Witte Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease Pediatr Infect Dis J 21 2002 796 797
92. H. Matsuda, Y. Kawakami, K. Furuya, Y. Kikuchi Intrauterine therapy for a cytomegalovirus-infected symptomatic fetus BJOG 111 2004 756 757
93. M.G. Revello, M. Zavattoni, M. Furione Quantification of human cytomegalovirus DNA in amniotic fluid of mothers of congenitally infected fetuses J Clin Microbiol 37 1999 3350 3352
94. S.P. Adler, J.W. Finney, A.M. Manganello, A.M. Best Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors a randomized controlled trial Pediatr Infect Dis J 15 1996 240 246
95. A.A. Arvin, P. Fast, M. Myers Vaccine Development to Prevent Cytomegalovirus Disease Report from the National Vaccine Advisory Committee Clin Infect Dis 39 2004 233 239