The use of quorum-sensing blockers as therapeutic agents for the control of biofilm-associated infections

Current Opinion in Investigational Drugs

Volumn 6, Issue 2, 2005, Pages 178-184

  Rice, Scott A ^a   McDougald, Diane ^a   Kumar, Naresh ^a   Kjelleberg, Staffan ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Antimicrobials; Bacterial pathogenesis; Biofilms; Cell cell signaling; Furanones; Novel therapeutics; Pseudomonas; Quorum sensing; Serratia; Vibrio

Indexed keywords

2,5 DIMETHYL 4 HYDROXY 3(2H)FURANONE; 5 METHYL 4 HYDROXY 3(2H)FURANONE; 5' METHYLTHIOADENOSINE; ACETIC ACID; ADENOSYLHOMOCYSTEINASE INHIBITOR; AMIDASE; ANTIBIOTIC AGENT; ANTIBODY; BACTERIAL PROTEIN; BENZOIC ACID; FORMYCIN; FURANONE DERIVATIVE; LACTONE DERIVATIVE; N ACYLATED HOMOSERINE LACTONE; PROPIONATE SODIUM; PROPIONIC ACID DERIVATIVE; PROTEIN AUTOINDUCER 2; S RIBOSYLHOMOCYSTEINASE; SODIUM DERIVATIVE; TOBRAMYCIN; TRICLOSAN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; DRUG DERIVATIVE; HOMOSERINE; LACTONE; LIGASE; N ACYLHOMOSERINE LACTONE SYNTHASE; N OCTANOYLHOMOSERINE LACTONE; N-ACYLHOMOSERINE LACTONE SYNTHASE; N-OCTANOYLHOMOSERINE LACTONE;

ANTIBIOTIC RESISTANCE; BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BIOFILM; CELL TRANSFORMATION; DRUG INHIBITION; DRUG MECHANISM; DRUG TARGETING; GENE MUTATION; NONHUMAN; QUORUM SENSING; REVIEW; SECOND MESSENGER; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; BACTERIUM; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MICROBIOLOGY;

ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL INFECTIONS; BIOFILMS; HOMOSERINE; LACTONES; LIGASES; SIGNAL TRANSDUCTION;

EID: 15744378878     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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