Crystal structure of foot-and-mouth disease virus 3C protease: New insights into catalytic mechanism and cleavage specificity

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11520-11527

  Birtley, James R ^a   Knox, Stephen R ^b   Jaulent, Agnès M ^b   Brick, Peter ^a   Leatherbarrow, Robin J ^b   Curry, Stephen ^a  

^a The Blackett Laboratory   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGRICULTURE; BIOCHEMISTRY; CATALYSIS; CHEMICAL BONDS; CRYSTAL STRUCTURE; DISEASE CONTROL; DISEASES; GENES; MOLECULAR BIOLOGY; RNA; VIRUSES;

CLEAVAGE SPECIFICITY; FOOT-AND-MOUTH DISEASE VIRUS (FMDV); FUNCTIONAL PROTEINS; SERINE PROTEASES;

ENZYMES;

ANTIVIRUS AGENT; ASPARTIC ACID; CHYMOTRYPSIN; CYSTEINE; FOOT AND MOUTH DISEASE VACCINE; FOOT AND MOUTH DISEASE VIRUS 3C PROTEASE; HISTIDINE; PROTEINASE; PROTEINASE INHIBITOR; SERINE PROTEINASE; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISEASE CONTROL; ENZYME SPECIFICITY; FOOT AND MOUTH DISEASE VIRUS; LIVESTOCK; NONHUMAN; PICORNAVIRUS; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLIZATION; CYSTEINE ENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; VIRAL PROTEINS;

CATALYSTS; CRYSTAL STRUCTURE; DISEASES; ENZYMES; VIRUSES;

FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE;

EID: 15744372994     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413254200     Document Type: Article

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