The structure of the superantigen exfoliative toxin a suggests a novel regulation as a serine protease

Biochemistry

Volumn 36, Issue 7, 1997, Pages 1564-1566

  Vath, Gregory M ^a   Earhart, Cathleen A ^a   Rago, James V ^a   Kim, Michael H ^a   Bohach, Gregory A ^b   Schlievert, Patrick M ^a   Ohlendorf, Douglas H ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF IDAHO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SERINE PROTEINASE; STAPHYLOCOCCUS ALPHA TOXIN;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; EXFOLIATIVE DERMATITIS; LYMPHOCYTE PROLIFERATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; STAPHYLOCOCCUS INFECTION; STRUCTURE ANALYSIS; T LYMPHOCYTE; TOXIC EPIDERMAL NECROLYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENDOPEPTIDASES; ENTEROTOXINS; GLUTAMIC ACID; HYDROLYSIS; MITOGENS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPERANTIGENS;

STAPHYLOCOCCUS;

EID: 0031028889     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962614f     Document Type: Article

References (51)

1. Acharya, K. R., Passalacqua, E. F., Jones, E. Y., Harlos, K., Stuart, D. I., Brehm, R. D., & Tranter, H. S. (1994) Nature 367, 94-97.
2. Allaire, M., Chernaia, M. M., Malcolm, B. A., & James, M. N. G. (1994) Nature 369, 72-76.
3. Bailey, C. J., & Smith, T. P. (1990) FEBS Lett. 269, 535-537.
4. Bailey, C. J., Lockhart, B. P., Redpath, M. B., & Smith, T. P. (1995) Med. Microbiol. Immunol. 184, 53-61.
5. Bar-Shavit, R., Kahn, A. J., Mann, K. G., & Wilner, G. D. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 976-980.
6. Barsumian, E. L., Schlievert, P. M., & Watson, D. W. (1978) Infect. Immun. 22, 681-688.
7. Bergmann, E. M., Mosimann, S. C., Chernaia, M. M., Malcom, B. A., & James, M. N. G. (1997) J. Virol. (in press).
8. Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S. R., & Hofsteenge, J. (1989) EMBO J. 8, 3467-3475.
9. Bohach, G. A., Fast, D. J., Nelson, R. D., & Schlievert, P. M. (1990) Crit. Rev. Microbiol. 17, 251-272.
10. Brünger, A. T. (1990) X-PLOR Version 3: A System for Crystal-lography and NMR, Yale University Press, New Haven, CT.
11. Collaborative Computational Project, Number 4 (1994) Acta Crystallogr. D50, 760-763.
12. Cowtan, K. (1994) Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography, Vol. 31, pp 34-38.
13. Dancer, S. J., Garratt, R., Saldanha, J., Jhoti, H., & Evans, R. (1990) FEBS Lett. 268, 129-132.
14. Elias, P. M., Fritsch, P., & Epstein, E. H. (1977) Arch. Dermatol. 113, 207-219.
15. Fields, B. A., Malchiodi, E. L., Li, H., Ysern, X., Stauffacher, C. V., Schlievert, P. M., Karjalainen, S., & Mariuzza, R. A. (1996) Nature 384, 188-192.
16. Fleischer, B., & Bailey, C. J. (1992) Med. Microbiol. Immunol. 180, 273-278.
17. Gershkovich, A. A. (1996) Biochemistry (Moscow) 61, 817-824.
18. Graf, L., Craik, C. S., Patthy, A., Roczniak, S., Fletterick, R. J., & Rutter, W. J. (1987) Biochemistry 26, 2616-2623.
19. Hoffmann, M. L., Jablanski, L. M., Crum, K. K., Hackett, S. P., Chi, Y. I., Stauffacher, C. V., Stevens, D. L., & Bohach, G. A. (1994) Infect. Immun. 62, 3396-3407.
20. Howard, A. J., Gilliland, G. L., Finzel, B. C., Poulos, T. L., Ohlendorf, D. H., & Salemme, F. R. (1987) J Appl. Crystallogr. 20, 383-387.
21. Jardetsky, T. S., Brown, J. H., Gorga, J. C., Stern, L. J., Urban, R. G., Chi, Y.-I., Stauffacher, C. V., Strominger, J. L., & Wiley, D. C. (1994) Nature 368, 711-718.
22. Jones, A. T., Zou, J. Y., Cowan, S. W., & Kjeldgaard, M. (1991) Acta Crystallogr. A47, 110-119.
23. Kim, J., Urban, R. G., Strominger, J. L., & Wiley, D. C. (1994) Science 266, 1870-1874.
24. Kim, J. L., Morgenstern, K. A., Lin, C., Fox, T., Dwyer, M. D., Landro, J. A., Chambers, S. P., Markland, W., Lepre, C. A., O'Malley, E. T., Harbeson, S. L., Rice, C. M., Murcko, M. A., Caron, P. R., & Thomson, J. A. (1996) Cell 87, 343-355.
25. Komiyama, T., Bigler, T. L., Yoshida, N., Noda, D., & Laskowski, M. (1991) J. Biol. Chem. 266, 10727-10730.
26. Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
27. Lee, C. Y., Schmidt, J. J., Johnson-Winegar, A. D., Spero, L., & Iandolo, J. J. (1987) J. Bacterial. 169, 3904-3909.
28. Lee, P. K., Deringer, J. R., Kreiswirth, B. N., Novick, R. P., & Schlievert, P. M. (1991) Infect. Immun. 59, 879-884.
29. Levitt, G., & Banaszak, L. J. (1993) J. Appl. Crystallogr. 26, 736-745.
30. Marrack, P., & Kappler, J. (1990) Science 248, 705-711.
31. McLay, A. L. C., Arbuthnott, J. P., & Lyell, A. (1975) J. Invest. Dermatol. 65, 423-428.
32. Melish, M. F., Glasgow, L. A., & Turner, M. D. (1972) J. Infect. Dis. 125, 129-140.
33. Morlock, B. A., Spero, L., & Johnson, A. D. (1980) Infect. Immun. 30, 381-384.
34. Murray, D. L., Earhart, C. A., Mitchell, D. T., Ohlendorf, D. H., Novick, R. P., & Schlievert, P. M. (1995) Infect. Immun. 64, 371-374.
35. Navaza, J. (1994) Acta Crystallogr. A50, 157-163.
36. Nienaber, V. L., Breddam, K., & Birktoft, J. J. (1993) Biochemistry 32, 11469-11475.
37. Nishioka, K., Katayama, I., & Sano, S. (1981) J. Dermatol. 8, 7-12.
38. O'Toole, P. W., & Foster, T. J. (1987) J. Bacterial. 169, 3910-3915.
39. Papageorgiou, A. C., Acharya, K. R., Shapiro, R., Passalacqua, E. F., Brehm, R. D., & Tranter, H. S. (1995) Structure 3, 769-779.
40. Perona, J. J., & Craik, C. S. (1995) Protein Sci. 4, 337-360.
41. Prasad, G. S., Earhart, C. A., Murray, D. L., Novick, R. P., Schlievert, P. M., & Ohlendorf, D. H. (1993) Biochemistry 32, 13761-13766.
42. Prevost, G., Rifai, S., Chaix, M. L., & Piemont, Y. (1991) Infect. Immun. 59, 3337-3339.
43. Prevost, G., Rifai, S., Chaix, M. L., Meyer S., & Piemont, Y. (1992) in Bacterial protein toxins (Witholt, B., et al., Eds.) pp 488-489, Fischer, Stuttgart.
44. Redpath M. B., Foster T. J., & Bailey C. J. (1991) FEMS Microbiol Lett. 81, 151-156.
45. Rogolsky, M. (1979) Microbiol. Rev. 43, 320-360.
46. Sakurai, S., & Kondo, I. (1978) Jpn. J. Med. Sci. Biol. 31, 208-211.
47. Schad, E. M., Zaitseva, I., Zaitsev, V. N., Dohlsten, M., Kalland, T., Schlievert, P. M., Ohlendorf, D. H., & Svensson, L. A. (1995) EMBO J. 14, 3292-3301.
48. Schlechter, I., & Berger, A. (1968) Biochem. Biophys, Res. Commun. 27, 157-162.
49. Swaminathan, S., Furey, W., Pletcher, J., & Sax, M. (1992) Nature 359, 801-806.
50. Wuepper, K. D., Dimond, R. L., & Knutson, D. D. (1975) J. Invest. Dermatol. 65, 191-200.
51. Yoo, C. S., Wang, B. C., Sax, M., & Johnson, A. D. (1978) J. Mol. Biol. 175, 421-423.