-
2
-
-
0037307081
-
Molecular modelling of ion chanels: Structural predictions
-
A. Giorgetti, and P. Carloni Molecular modelling of ion chanels: structural predictions Curr. Opin. Chem. Biol. 7 1 2003 150 156
-
(2003)
Curr. Opin. Chem. Biol.
, vol.7
, Issue.1
, pp. 150-156
-
-
Giorgetti, A.1
Carloni, P.2
-
3
-
-
0036797871
-
Ion channels: Structural bioinformatics and modelling
-
C.E Capener, H.J. Kim, Y. Arinaminpathy, and M.S. Sansom Ion channels: structural bioinformatics and modelling Hum. Mol. Genet. 11 20 2002 2425 2433
-
(2002)
Hum. Mol. Genet.
, vol.11
, Issue.20
, pp. 2425-2433
-
-
Capener, C.E.1
Kim, H.J.2
Arinaminpathy, Y.3
Sansom, M.S.4
-
4
-
-
0036020150
-
Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channels
-
M. Simoes, L. Garneau, H. Klein, U. Banderali, F. Hobeila, B. Roux, L. Parent, and R. Sauve Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channels J. Gen. Physiol. 120 1 2002 99 116
-
(2002)
J. Gen. Physiol.
, vol.120
, Issue.1
, pp. 99-116
-
-
Simoes, M.1
Garneau, L.2
Klein, H.3
Banderali, U.4
Hobeila, F.5
Roux, B.6
Parent, L.7
Sauve, R.8
-
5
-
-
0024805680
-
Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
-
U.B. Kaupp, T. Niidome, T. Tanabe, S. Terada, W. Bonigk, W. Stuhmer, N.J. Cook, K. Kangawa, H. Matsuo, and T. Hirose Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel Nature 342 1989 762 766
-
(1989)
Nature
, vol.342
, pp. 762-766
-
-
Kaupp, U.B.1
Niidome, T.2
Tanabe, T.3
Terada, S.4
Bonigk, W.5
Stuhmer, W.6
Cook, N.J.7
Kangawa, K.8
Matsuo, H.9
Hirose, T.10
-
6
-
-
0032888454
-
Cyclic nucleotide-gated channels. Pore topology studied through the accessibility of reporter cysteines
-
A. Becchetti, K. Gamel, and V. Torre Cyclic nucleotide-gated channels. Pore topology studied through the accessibility of reporter cysteines J. Gen. Physiol. 114 1999 377 392
-
(1999)
J. Gen. Physiol.
, vol.114
, pp. 377-392
-
-
Becchetti, A.1
Gamel, K.2
Torre, V.3
-
7
-
-
0029156541
-
The multi-ion nature of the cGMP-gated channel from vertebrate rods
-
F. Sesti, E. Eismann, U.B. Kaupp, M. Nizzari, and V. Torre The multi-ion nature of the cGMP-gated channel from vertebrate rods J. Physiol. 487 Pt. 1 1995 17 36
-
(1995)
J. Physiol.
, vol.487
, Issue.PART 1
, pp. 17-36
-
-
Sesti, F.1
Eismann, E.2
Kaupp, U.B.3
Nizzari, M.4
Torre, V.5
-
8
-
-
0035974844
-
Rotation movement during cyclic nucleotide-gated channel opening
-
J. Johnson, and W.N. Zagotta Rotation movement during cyclic nucleotide-gated channel opening Nature 412 2001 917 921
-
(2001)
Nature
, vol.412
, pp. 917-921
-
-
Johnson, J.1
Zagotta, W.N.2
-
9
-
-
0033213381
-
Molecular rearrangements in the ligand-binding domain of cyclic nucleotide-gated channels
-
K. Matulef, G.E. Flynn, and W.N. Zagotta Molecular rearrangements in the ligand-binding domain of cyclic nucleotide-gated channels Neuron 24 1999 443 452
-
(1999)
Neuron
, vol.24
, pp. 443-452
-
-
Matulef, K.1
Flynn, G.E.2
Zagotta, W.N.3
-
10
-
-
0037198625
-
The open pore conformation of potassium channels
-
Y. Jiang, A. Lee, J. Chen, M. Cadene, B.T. Chait, and R. MacKinnon The open pore conformation of potassium channels Nature 417 2002 523 526
-
(2002)
Nature
, vol.417
, pp. 523-526
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Cadene, M.4
Chait, B.T.5
MacKinnon, R.6
-
11
-
-
0035499892
-
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 Å resolution
-
Y. Zhou, J.H. Morais-Cabral, A. Kaufman, and R. MacKinnon Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 Å resolution Nature 414 2001 43 48
-
(2001)
Nature
, vol.414
, pp. 43-48
-
-
Zhou, Y.1
Morais-Cabral, J.H.2
Kaufman, A.3
MacKinnon, R.4
-
12
-
-
0141831003
-
Stuctural basis for modulation and agonist specificity of HCN pacemakers channels
-
W.N. Zagotta, N.B. Olivier, K.D. Black, E.C. Young, R. Olson, and E. Gouaux Stuctural basis for modulation and agonist specificity of HCN pacemakers channels Nature 425 2003 200 205
-
(2003)
Nature
, vol.425
, pp. 200-205
-
-
Zagotta, W.N.1
Olivier, N.B.2
Black, K.D.3
Young, E.C.4
Olson, R.5
Gouaux, E.6
-
13
-
-
0034520641
-
Change of pore helix conformational state upon opening of cyclic nucleotide-gated channels
-
J. Liu, and S.A. Siegelbaum Change of pore helix conformational state upon opening of cyclic nucleotide-gated channels Neuron 28 2000 899 909
-
(2000)
Neuron
, vol.28
, pp. 899-909
-
-
Liu, J.1
Siegelbaum, S.A.2
-
14
-
-
0034977038
-
Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels
-
G.E. Flynn, and W.N. Zagotta Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels Neuron 30 2001 689 698
-
(2001)
Neuron
, vol.30
, pp. 689-698
-
-
Flynn, G.E.1
Zagotta, W.N.2
-
15
-
-
0037904401
-
A cysteine scan of the inner vestibule of cyclic nucleotide-gated channels reveals architecture and rearrangement of the pore
-
G.E. Flynn, and W.N. Zagotta A cysteine scan of the inner vestibule of cyclic nucleotide-gated channels reveals architecture and rearrangement of the pore J. Gen. Physiol 121 2001 563 582
-
(2001)
J. Gen. Physiol
, vol.121
, pp. 563-582
-
-
Flynn, G.E.1
Zagotta, W.N.2
-
16
-
-
0035461292
-
Cyclic nucleotide-gated channels: Shedding light on the opening of a channel pore
-
G.E. Flynn, J.P. Johnson, and W.N. Zagotta Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore Nat. Rev. Neurosci. 2 2001 643 651
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 643-651
-
-
Flynn, G.E.1
Johnson, J.P.2
Zagotta, W.N.3
-
17
-
-
0035974844
-
Rotational movement during cyclic nucleotide-gated channel opening
-
J.P. Johnson, and W.N. Zagotta Rotational movement during cyclic nucleotide-gated channel opening Nature 412 2001 917 921
-
(2001)
Nature
, vol.412
, pp. 917-921
-
-
Johnson, J.P.1
Zagotta, W.N.2
-
18
-
-
85030806664
-
Conformational changes in the S6 domain of CNGA1 channels probed by intracellular Cd(II)
-
submitted
-
Mazzolini, M., Codega, P., Nair, A.V, Giorgetti, A., Torre, V. Conformational changes in the S6 domain of CNGA1 channels probed by intracellular Cd(II), J. Gen. Physiol., submitted
-
J. Gen. Physiol.
-
-
Mazzolini, M.1
Codega, P.2
Nair, A.V.3
Giorgetti, A.4
Torre, V.5
-
19
-
-
85030811393
-
Conformational changes in the pore of CNGA1 channels during gating, revealed by electrophysiological experiments with mutant channels
-
submitted
-
Nair, A.V., Mazzolini, M., Codega, P., Giorgetti, A., Torre, V. Conformational changes in the pore of CNGA1 channels during gating, revealed by electrophysiological experiments with mutant channels, J. Gen. Physiol., submitted
-
J. Gen. Physiol.
-
-
Nair, A.V.1
Mazzolini, M.2
Codega, P.3
Giorgetti, A.4
Torre, V.5
-
20
-
-
0033931448
-
2+ of substituted cysteine residues within the P-loop
-
2+ of substituted cysteine residues within the P-loop Pflugers Arch. 440 2000 556 565
-
(2000)
Pflugers Arch.
, vol.440
, pp. 556-565
-
-
Becchetti, A.1
Roncaglia, P.2
-
21
-
-
0036143456
-
Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel
-
B. Rothberg, K. Shin, P. Phale, and G. Yellen Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel J. Gen. Physiol. 119 2002 2002 83 91
-
(2002)
J. Gen. Physiol.
, vol.119
, Issue.2002
, pp. 83-91
-
-
Rothberg, B.1
Shin, K.2
Phale, P.3
Yellen, G.4
-
22
-
-
0033954256
-
The Protein Data Bank
-
H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, and P.E. Bourne The Protein Data Bank Nucleic Acids Res. 28 2000 235 242
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
23
-
-
85030807950
-
-
note
-
2+ binding, is not consistent with the whole set of (about 22 experiments) data on the C-linker from N400C to R442C and it is therefore not included here
-
-
-
-
24
-
-
0026485739
-
Acetylcholine receptor channel structure probed in cysteine-substitution mutants
-
M.H. Akabas, D.A. Stauffer, M. Xu, and A. Karlin Acetylcholine receptor channel structure probed in cysteine-substitution mutants Science 258 1992 307 310
-
(1992)
Science
, vol.258
, pp. 307-310
-
-
Akabas, M.H.1
Stauffer, D.A.2
Xu, M.3
Karlin, A.4
-
25
-
-
85030810391
-
-
note
-
2+ adducts (Table 1) resulted in extremely large rearrangements (more than 10 Å), while causing relatively small rearrangements (overall RMSD of 3 Å) (Fig. 2) in the KcsA-based model. Thus, MthK was not considered any further
-
-
-
-
26
-
-
1942467020
-
Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges
-
S.M. Webster, D. del Camino, J.P. Dekker, and G. Yellen Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges Nature 428 2004 864 868
-
(2004)
Nature
, vol.428
, pp. 864-868
-
-
Webster, S.M.1
Del Camino, D.2
Dekker, J.P.3
Yellen, G.4
-
27
-
-
0027194224
-
Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels
-
E.H. Goulding, G.R. Tibbs, D. Liu, and S.A. Siegelbaum Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels Nature 364 1993 61 64
-
(1993)
Nature
, vol.364
, pp. 61-64
-
-
Goulding, E.H.1
Tibbs, G.R.2
Liu, D.3
Siegelbaum, S.A.4
-
28
-
-
0029994037
-
Time-dependent current decline in cyclic GMP-gated bovine channels caused by point mutations in the pore region expressed in Xenopus oocytes
-
G. Bucossi, E. Eismann, F. Sesti, M. Nizzari, M. Seri, U.B. Kaupp, and V. Torre Time-dependent current decline in cyclic GMP-gated bovine channels caused by point mutations in the pore region expressed in Xenopus oocytes J. Physiol. 493 Pt. 2 1996 409 418
-
(1996)
J. Physiol.
, vol.493
, Issue.PART 2
, pp. 409-418
-
-
Bucossi, G.1
Eismann, E.2
Sesti, F.3
Nizzari, M.4
Seri, M.5
Kaupp, U.B.6
Torre, V.7
-
29
-
-
0032939643
-
Physical origin of selectivity in ionic channels of biological membranes
-
A. Laio, and V. Torre Physical origin of selectivity in ionic channels of biological membranes Biophys. J. 76 1999 129 148
-
(1999)
Biophys. J.
, vol.76
, pp. 129-148
-
-
Laio, A.1
Torre, V.2
-
30
-
-
0032478818
-
The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
-
D.A. Doyle, J. Morais-Cabral, R.A. Pfuetzner, A. Kuo, J.M. Gulbis, S.L. Cohen, B.T. Chait, and R. MacKinnon The structure of the potassium channel: molecular basis of K+ conduction and selectivity Science 280 1998 69 77
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais-Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
31
-
-
85030807151
-
-
The final models can be found in the following web address: www.sissa.it/sbp/web/research/biomolecular_simulations/pdbfiles/
-
-
-
-
32
-
-
0030908273
-
Advances in comparative protein-structure modelling
-
R. Sanchez, and A. Sali Advances in comparative protein-structure modelling Curr. Opin. Struct. Biol. 7 1997 206 214
-
(1997)
Curr. Opin. Struct. Biol.
, vol.7
, pp. 206-214
-
-
Sanchez, R.1
Sali, A.2
|