메뉴 건너뛰기




Volumn 440, Issue 4, 2000, Pages 556-565

Cyclic nucleotide-gated channels: Intra- and extracellular accessibility to Cd2+ of substituted cysteine residues within the P-loop

Author keywords

CNG channels; Gating; H5; Pore loop; Scanning cysteine mutagenesis; Sulfhydryl specific reagents

Indexed keywords

CADMIUM; CYCLIC NUCLEOTIDE; ION CHANNEL; THIOL DERIVATIVE;

EID: 0033931448     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050006     Document Type: Article
Times cited : (33)

References (40)
  • 1
    • 0032855688 scopus 로고    scopus 로고
    • The properties of cysteine mutants in the pore region of cyclic nucleotide-gated channels
    • 1. Becchetti A, Gamel K (1999) The properties of cysteine mutants in the pore region of cyclic nucleotide-gated channels. Pflügers Arch 438:587-596
    • (1999) Pflügers Arch , vol.438 , pp. 587-596
    • Becchetti, A.1    Gamel, K.2
  • 2
    • 0032888454 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated channels: Pore topology studied through the accessibility of reporter cysteines
    • 2. Becchetti A, Gamel K, Torre V (1999) Cyclic nucleotide-gated channels: pore topology studied through the accessibility of reporter cysteines. J Gen Physiol 114:377-392
    • (1999) J Gen Physiol , vol.114 , pp. 377-392
    • Becchetti, A.1    Gamel, K.2    Torre, V.3
  • 3
    • 0029994037 scopus 로고    scopus 로고
    • Time dependent current decline in cyclic GMP gated channels caused by point mutations in the pore region
    • 3. Bucossi G, Eismann E, Sesti F, Nizzari M, Seri M, Kaupp UB, Torre V (1996) Time dependent current decline in cyclic GMP gated channels caused by point mutations in the pore region. J Physiol (Lond) 493:409-418
    • (1996) J Physiol (Lond) , vol.493 , pp. 409-418
    • Bucossi, G.1    Eismann, E.2    Sesti, F.3    Nizzari, M.4    Seri, M.5    Kaupp, U.B.6    Torre, V.7
  • 4
    • 0031055302 scopus 로고    scopus 로고
    • Single-channel properties of ionic channels gated by cyclic nucleotides
    • 4. Bucossi G, Nizzari M, Torre V (1997) Single-channel properties of ionic channels gated by cyclic nucleotides. Biophys J 72:1165-1181
    • (1997) Biophys J , vol.72 , pp. 1165-1181
    • Bucossi, G.1    Nizzari, M.2    Torre, V.3
  • 5
    • 0025799763 scopus 로고
    • Blockage and permeation of divalent cations through the cyclic GMP-activated channel from tiger salamander retinal rods
    • 5. Colamartino G, Menini A, Torre V (1991) Blockage and permeation of divalent cations through the cyclic GMP-activated channel from tiger salamander retinal rods. J Physiol (Lond.) 440:189-206
    • (1991) J Physiol (Lond.) , vol.440 , pp. 189-206
    • Colamartino, G.1    Menini, A.2    Torre, V.3
  • 7
    • 0032528923 scopus 로고    scopus 로고
    • The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis
    • 7. Dart C, Leyland ML, Spencer PJ, Stanfield PR, Sutcliffe MJ (1998) The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis. J Physiol (Lond) 511:25-32
    • (1998) J Physiol (Lond) , vol.511 , pp. 25-32
    • Dart, C.1    Leyland, M.L.2    Spencer, P.J.3    Stanfield, P.R.4    Sutcliffe, M.J.5
  • 9
    • 0031877384 scopus 로고    scopus 로고
    • + channels in open, closed and inactivated conformations
    • + channels in open, closed and inactivated conformations. J Struct Biol 121:263-284
    • (1998) J Struct Biol , vol.121 , pp. 263-284
    • Durell, S.R.1    Hao, Y.2    Guy, H.R.3
  • 10
    • 0028047839 scopus 로고
    • A single negative charge within the pore region of a cGMP-gated channel controls rectification, Ca blockage, and ionic selectivity
    • 10. Eismann E, Muller F, Heinemann S, Kaupp UB (1994) A single negative charge within the pore region of a cGMP-gated channel controls rectification, Ca blockage, and ionic selectivity. Proc Natl Acad Sci USA 91:1109-1113
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1109-1113
    • Eismann, E.1    Muller, F.2    Heinemann, S.3    Kaupp, U.B.4
  • 11
    • 0030665893 scopus 로고    scopus 로고
    • Tetracaine reports a conformational change in the pore of cyclic nucleotide-gated channels
    • 11. Fodor AA, Black KD, Zagotta WA (1997) Tetracaine reports a conformational change in the pore of cyclic nucleotide-gated channels. J Gen Physiol 110:591-600
    • (1997) J Gen Physiol , vol.110 , pp. 591-600
    • Fodor, A.A.1    Black, K.D.2    Zagotta, W.A.3
  • 12
    • 0024393637 scopus 로고
    • A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning
    • 12. Frech GC, VanDongen AMJ, Schuster G, Brown AM, Joho RH (1989) A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature 340:642-645
    • (1989) Nature , vol.340 , pp. 642-645
    • Frech, G.C.1    VanDongen, A.M.J.2    Schuster, G.3    Brown, A.M.4    Joho, R.H.5
  • 13
    • 0026410002 scopus 로고
    • Structural aspects of metal liganding to functional groups in proteins
    • 13. Glusker JP (1991) Structural aspects of metal liganding to functional groups in proteins. Adv Prot Chem 42:1-76
    • (1991) Adv Prot Chem , vol.42 , pp. 1-76
    • Glusker, J.P.1
  • 14
    • 0028821215 scopus 로고
    • A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors
    • 14. Gordon SE, Zagotta WN (1995) A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors. Neuron 14:177-183
    • (1995) Neuron , vol.14 , pp. 177-183
    • Gordon, S.E.1    Zagotta, W.N.2
  • 15
    • 0030051784 scopus 로고    scopus 로고
    • Agitoxin footprinting the Shaker potassium channel pore
    • 15. Gross A, MacKinnon R (1996) Agitoxin footprinting the Shaker potassium channel pore. Neuron 16:399-406
    • (1996) Neuron , vol.16 , pp. 399-406
    • Gross, A.1    MacKinnon, R.2
  • 16
    • 0019441262 scopus 로고
    • Improved patch-clamp technique for high resolution current recording from cells and cell-free membrane patches
    • 16. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp technique for high resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100
    • (1981) Pflügers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 18
    • 0029860763 scopus 로고    scopus 로고
    • On the use of thiol-modifying agents to determine channel topology
    • 18. Holmgren M, Liu Y, Xu Y, Yellen G (1996) On the use of thiol-modifying agents to determine channel topology. Neuropharmacology 35:797-804
    • (1996) Neuropharmacology , vol.35 , pp. 797-804
    • Holmgren, M.1    Liu, Y.2    Xu, Y.3    Yellen, G.4
  • 19
    • 0025820873 scopus 로고
    • Single-channel study of the cGMP-dependent conductance of retinal rods from incorporation of native vescicles into planar lipid bilayers
    • 19. Ildefonse M, Bennett N (1991) Single-channel study of the cGMP-dependent conductance of retinal rods from incorporation of native vescicles into planar lipid bilayers. J Membr Biol 123:133-147
    • (1991) J Membr Biol , vol.123 , pp. 133-147
    • Ildefonse, M.1    Bennett, N.2
  • 20
    • 0025307123 scopus 로고
    • A superfamily of ion channels
    • 20. Jan LY, Jan YN (1990) A superfamily of ion channels. Nature 345:672
    • (1990) Nature , vol.345 , pp. 672
    • Jan, L.Y.1    Jan, Y.N.2
  • 21
    • 0032321487 scopus 로고    scopus 로고
    • Substituted-cysteine accessibility method
    • Conn PM (ed). Academic, San Diego
    • 21. Karlin A, Akabas MH (1998) Substituted-cysteine accessibility method. In: Conn PM (ed) Methods in enzymology. Academic, San Diego, pp 123-145
    • (1998) Methods in Enzymology , pp. 123-145
    • Karlin, A.1    Akabas, M.H.2
  • 22
    • 0027418442 scopus 로고
    • Interaction between divalent cations and the gating machinery of cyclic GMP-activated channels in salamander retinal rods
    • 22. Karpen JW, Lane Brown L, Stryer L, Baylor DA (1993) Interaction between divalent cations and the gating machinery of cyclic GMP-activated channels in salamander retinal rods. J Gen Physiol 101:1-25
    • (1993) J Gen Physiol , vol.101 , pp. 1-25
    • Karpen, J.W.1    Lane Brown, L.2    Stryer, L.3    Baylor, D.A.4
  • 24
    • 0001505616 scopus 로고
    • Ligand variation and metal ion binding specificity in zinc fingers peptides
    • 24. Krizek BA, Merkle DL, Berg JM (1993) Ligand variation and metal ion binding specificity in zinc fingers peptides. Inorg Chem 32:937-940
    • (1993) Inorg Chem , vol.32 , pp. 937-940
    • Krizek, B.A.1    Merkle, D.L.2    Berg, J.M.3
  • 26
    • 0032508478 scopus 로고    scopus 로고
    • Probing pore topology and conformational changes of Kir2.1 potassium channels by cysteine scanning mutagenesis
    • 26. Kubo Y, Yoshimichi M, Heinemann SH (1998) Probing pore topology and conformational changes of Kir2.1 potassium channels by cysteine scanning mutagenesis. FEBS Lett 435:69-73
    • (1998) FEBS Lett , vol.435 , pp. 69-73
    • Kubo, Y.1    Yoshimichi, M.2    Heinemann, S.H.3
  • 27
    • 0028941130 scopus 로고
    • + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis
    • + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys J 68:900-905
    • (1995) Biophys J , vol.68 , pp. 900-905
    • Kurz, L.L.1    Zuhlke, R.D.2    Zhang, H.-J.3    Joho, R.H.4
  • 29
    • 0028960949 scopus 로고
    • Silver as a probe of pore-forming residues in a potassium channel
    • 29. Lu Q, Miller C (1995) Silver as a probe of pore-forming residues in a potassium channel. Science 268:304-307
    • (1995) Science , vol.268 , pp. 304-307
    • Lu, Q.1    Miller, C.2
  • 33
    • 0029070117 scopus 로고
    • + pore structure revealed by reporter cysteines at inner and outer surfaces
    • + pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron 14:1055-1063
    • (1995) Neuron , vol.14 , pp. 1055-1063
    • Pascual, J.M.1    Shieh, C.C.2    Kirsch, G.E.3    Brown, A.M.4
  • 34
    • 0027424793 scopus 로고
    • Identification of an external divalent binding site in the pore of a cGMP-activated channel
    • 34. Root MJ, MacKinnon R (1993) Identification of an external divalent binding site in the pore of a cGMP-activated channel. Neuron 11:459-466
    • (1993) Neuron , vol.11 , pp. 459-466
    • Root, M.J.1    MacKinnon, R.2
  • 35
    • 0028841033 scopus 로고
    • A prokaryotic potassium ion channel with two predicted transmembrane transmembrane segments from Streptomyces lividans
    • 35. Schrempf H, Schmidt O, Kummerlen R, Hinnah S, Muller D, Betzler M, Steinkamp T, Wagner R (1995) A prokaryotic potassium ion channel with two predicted transmembrane transmembrane segments from Streptomyces lividans. EMBO J 14:5170-5178
    • (1995) EMBO J , vol.14 , pp. 5170-5178
    • Schrempf, H.1    Schmidt, O.2    Kummerlen, R.3    Hinnah, S.4    Muller, D.5    Betzler, M.6    Steinkamp, T.7    Wagner, R.8
  • 36
  • 37
    • 0030057048 scopus 로고    scopus 로고
    • Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating
    • 37. Sun Z-P, Akabas MH, Goulding EH, Karlin A, Siegelbaum SA (1996) Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating. Neuron 16:141-149
    • (1996) Neuron , vol.16 , pp. 141-149
    • Sun, Z.-P.1    Akabas, M.H.2    Goulding, E.H.3    Karlin, A.4    Siegelbaum, S.A.5
  • 38
    • 0023270432 scopus 로고
    • Sequence of a probable potassium channel component encoded at the Shaker locus of Drosophila
    • 38. Tempel BL, Papazian DM, Schwartz TL, Jan YN, Jan LY (1987) Sequence of a probable potassium channel component encoded at the Shaker locus of Drosophila. Science 237: 770-775
    • (1987) Science , vol.237 , pp. 770-775
    • Tempel, B.L.1    Papazian, D.M.2    Schwartz, T.L.3    Jan, Y.N.4    Jan, L.Y.5
  • 40
    • 0029998701 scopus 로고    scopus 로고
    • Structure and function of cyclic nucleotide-gated channels
    • 40. Zagotta WN, Siegelbaum SA (1996) Structure and function of cyclic nucleotide-gated channels. Annu Rev Neurosci 19: 135-263
    • (1996) Annu Rev Neurosci , vol.19 , pp. 135-263
    • Zagotta, W.N.1    Siegelbaum, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.