Mitochondrial trifunctional protein defects: Molecular basis and novel therapeutic approaches

Current Drug Targets: Immune, Endocrine and Metabolic Disorders

Volumn 5, Issue 1, 2005, Pages 27-40

  Angdisen, J ^a   Moore, V D G ^a   Cline, J M ^a   Payne, R M ^a   Ibdah, J A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

oxidation; Fatty acids; Fusion proteins; LCHAD; Mitochondria; Mitochondrial trifunctional protein; PDT; TAT

Indexed keywords

ADENOVIRUS VECTOR; ANTENNAPEDIA PROTEIN; BREFELDIN A; CARNITINE; COMPLEMENTARY DNA; DIETHYLAMINOETHYLDEXTRAN; DNA; DNA BINDING PROTEIN; FATTY ACID; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LENTIVIRUS VECTOR; LIPID; LONG CHAIN FATTY ACID; MALATE DEHYDROGENASE; MATRIX PROTEIN; MEDIUM CHAIN FATTY ACID; MITOCHONDRIAL PROTEIN; POLYMER; PROTEIN VP22; REGULATOR PROTEIN; RETROVIRUS VECTOR; ROTENONE; TRANSACTIVATOR PROTEIN; VIRUS RNA;

CARDIOMYOPATHY; CELLULAR DISTRIBUTION; DIET RESTRICTION; DIET SUPPLEMENTATION; DIET THERAPY; FATTY ACID OXIDATION; FOOD INTAKE; GENE CONSTRUCT; GENE MUTATION; GENETIC TRANSFECTION; GENOTYPE PHENOTYPE CORRELATION; HEART ARRHYTHMIA; HELLP SYNDROME; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; INBORN ERROR OF METABOLISM; LIVER DISEASE; LIVER DYSFUNCTION; LONG TERM CARE; LOW FAT DIET; MITOCHONDRION; MOLECULAR MECHANICS; NEUROMUSCULAR DISEASE; NONHUMAN; OUTCOMES RESEARCH; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; STEM CELL TRANSPLANTATION; SUDDEN INFANT DEATH SYNDROME; VIRAL GENE DELIVERY SYSTEM;

AMINO ACID SEQUENCE; ANIMALS; GENE THERAPY; HUMANS; LIPID METABOLISM, INBORN ERRORS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTATION;

EID: 15444372353     PISSN: 15680088     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568008053174796     Document Type: Review

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