-
1
-
-
0000997059
-
Systemic hypertension: Mechanisms and diagnosis
-
Braunwald E, editor. Pennsylvania: W.B. Saunders Company
-
Kaplan NM. Systemic hypertension: mechanisms and diagnosis. In: Braunwald E, editor. Heart Disease. A textbook of cardiovascular medicine 5th ed. Pennsylvania: W.B. Saunders Company; 1997. pp. 807-839.
-
(1997)
Heart Disease. A Textbook of Cardiovascular Medicine 5th Ed.
, pp. 807-839
-
-
Kaplan, N.M.1
-
2
-
-
0035145934
-
The genetics of essential hypertension
-
O'Shaughnessy KM. The genetics of essential hypertension. Br J Clin Pharmacol 2001; 51:5-11.
-
(2001)
Br J Clin Pharmacol
, vol.51
, pp. 5-11
-
-
O'Shaughnessy, K.M.1
-
3
-
-
0035936780
-
Molecular mechanisms of human hypertension
-
Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell 2001; 104:545-556.
-
(2001)
Cell
, vol.104
, pp. 545-556
-
-
Lifton, R.P.1
Gharavi, A.G.2
Geller, D.S.3
-
4
-
-
0033755028
-
Genetics of hypertension: From experimental models to clinical applications
-
Lee WK, Padmanabhan S, Dominiczak AF. Genetics of hypertension: from experimental models to clinical applications. J Hum Hypertens 2000; 14:631-647.
-
(2000)
J Hum Hypertens
, vol.14
, pp. 631-647
-
-
Lee, W.K.1
Padmanabhan, S.2
Dominiczak, A.F.3
-
5
-
-
0035138957
-
Molecular genetics of essential hypertension: Recent results and emerging strategies
-
Timberlake DS, O'Connor DT, Parmer RJ. Molecular genetics of essential hypertension: recent results and emerging strategies. Curr Opin Nephrol Hypertens 2001; 10:71-79.
-
(2001)
Curr Opin Nephrol Hypertens
, vol.10
, pp. 71-79
-
-
Timberlake, D.S.1
O'Connor, D.T.2
Parmer, R.J.3
-
6
-
-
0344271798
-
Genetics of hypertension
-
Hopkins PN, Hunt SC. Genetics of hypertension. Genet Med 2003; 5:413-429. A thorough review for molecular genetics of hypertension. Some results of genome-wide scans are summarized.
-
(2003)
Genet Med
, vol.5
, pp. 413-429
-
-
Hopkins, P.N.1
Hunt, S.C.2
-
8
-
-
0037862904
-
Where are all the blood-pressure genes?
-
Harrap SB. Where are all the blood-pressure genes? Lancet 2003; 361:2149-2151.
-
(2003)
Lancet
, vol.361
, pp. 2149-2151
-
-
Harrap, S.B.1
-
9
-
-
1842612033
-
Genetics of essential hypertension
-
Mein CA, Caulfield MJ, Dobson RJ, Munroe PB. Genetics of essential hypertension. Hum Mol Genet 2004; 13:R169-R175. An excellent review of the genetics of essential hypertension. Results from genome-wide scans for blood pressure, hypertension and pre-eclampsia genes are summarized and discussed.
-
(2004)
Hum Mol Genet
, vol.13
-
-
Mein, C.A.1
Caulfield, M.J.2
Dobson, R.J.3
Munroe, P.B.4
-
10
-
-
0033770421
-
Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study
-
Levy D, DeStefano AL, Larson MG, et al. Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study. Hypertension 2000; 36:477-483.
-
(2000)
Hypertension
, vol.36
, pp. 477-483
-
-
Levy, D.1
DeStefano, A.L.2
Larson, M.G.3
-
11
-
-
0034680349
-
Genome-wide linkage analysis of systolic and diastolic blood pressure: The Quebec Family Study
-
Rice T, Rankinen T, Province MA, et al. Genome-wide linkage analysis of systolic and diastolic blood pressure: the Quebec Family Study. Circulation 2000; 102:1956-1963.
-
(2000)
Circulation
, vol.102
, pp. 1956-1963
-
-
Rice, T.1
Rankinen, T.2
Province, M.A.3
-
12
-
-
0036278171
-
Genomewide linkage scan of resting blood pressure: HERITAGE Family Study. Health, Risk Factors, Exercise Training, and Genetics
-
Rice T, Rankinen T, Chagnon YC, et al. Genomewide linkage scan of resting blood pressure: HERITAGE Family Study. Health, Risk Factors, Exercise Training, and Genetics. Hypertension 2002; 39:1037-1043.
-
(2002)
Hypertension
, vol.39
, pp. 1037-1043
-
-
Rice, T.1
Rankinen, T.2
Chagnon, Y.C.3
-
13
-
-
0036318601
-
Genome scans for blood pressure and hypertension: The National Heart, Lung, and Blood Institute Family Heart Study
-
Hunt SC, Ellison RC, Atwood LD, et al. Genome scans for blood pressure and hypertension: the National Heart, Lung, and Blood Institute Family Heart Study. Hypertension 2002; 40:1-6.
-
(2002)
Hypertension
, vol.40
, pp. 1-6
-
-
Hunt, S.C.1
Ellison, R.C.2
Atwood, L.D.3
-
14
-
-
12244297741
-
A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans
-
Thiel BA, Chakravarti A, Cooper RS, et al. A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans. Am J Hypertens 2003; 16:151-153. A recent report of a genome-wide scan published during the review period.
-
(2003)
Am J Hypertens
, vol.16
, pp. 151-153
-
-
Thiel, B.A.1
Chakravarti, A.2
Cooper, R.S.3
-
15
-
-
0033755905
-
Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings
-
Perola M, Kainulainen K, Pajukanta P, et al. Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings. J Hypertens 2000; 18:1579-1585.
-
(2000)
J Hypertens
, vol.18
, pp. 1579-1585
-
-
Perola, M.1
Kainulainen, K.2
Pajukanta, P.3
-
16
-
-
0037307595
-
Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations
-
Kardia SL, Rozek LS, Krushkal J, et al. Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations. Am J Hypertens 2003; 16:154-157. A recent report of a genome-wide scan published during the review period.
-
(2003)
Am J Hypertens
, vol.16
, pp. 154-157
-
-
Kardia, S.L.1
Rozek, L.S.2
Krushkal, J.3
-
17
-
-
12244273672
-
A genome-wide affected sibpair linkage analysis of hypertension: The HyperGEN network
-
Rao DC, Province MA, Leppert MF, et al. A genome-wide affected sibpair linkage analysis of hypertension: the HyperGEN network. Am J Hypertens 2003; 16:148-150. A recent report of a genome-wide scan published during the review period.
-
(2003)
Am J Hypertens
, vol.16
, pp. 148-150
-
-
Rao, D.C.1
Province, M.A.2
Leppert, M.F.3
-
18
-
-
10744219593
-
A genome wide scan for early onset primary hypertension in Scandinavians
-
von Wowern F, Bengtsson K, Lindgren CM, et al. A genome wide scan for early onset primary hypertension in Scandinavians. Hum Mol Genet 2003; 12:2077-2081. A recent report of a genome-wide scan published during the review period.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2077-2081
-
-
Von Wowern, F.1
Bengtsson, K.2
Lindgren, C.M.3
-
19
-
-
5444222846
-
Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3
-
Koivukoski L, Fisher SA, Kanninen T, et al. Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3. Hum Mol Genet 2004; 13:2325-2332. This excellent meta-analysis of genome-wide scans should be used as a reference for upcoming genome scans.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2325-2332
-
-
Koivukoski, L.1
Fisher, S.A.2
Kanninen, T.3
-
20
-
-
0842328645
-
Functional genomics as an emerging strategy for the investigation of central mechanisms in experimental hypertension
-
Veerasingham SJ, Sellers KW, Raizada MK. Functional genomics as an emerging strategy for the investigation of central mechanisms in experimental hypertension. Prog Biophys Mol Biol 2004; 84:107-123. This review provides a good overview and some perspectives of functional genomics for hypertension research.
-
(2004)
Prog Biophys Mol Biol
, vol.84
, pp. 107-123
-
-
Veerasingham, S.J.1
Sellers, K.W.2
Raizada, M.K.3
-
21
-
-
0142085746
-
Physiological genomics of human arteries: Quantitative relationship between gene expression and arterial stiffness
-
Durier S, Fassot C, Laurent S, et al. Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. Circulation 2003; 108:1845-1851. This is one of the first studies in humans in which gene-expression profiles in tissue isolated from individual patients are correlated with a clinically relevant cardiovascular phenotype.
-
(2003)
Circulation
, vol.108
, pp. 1845-1851
-
-
Durier, S.1
Fassot, C.2
Laurent, S.3
-
22
-
-
0036175491
-
Physiological genomics: Implications in hypertension research
-
Glueck SB, Dzau VJ. Physiological genomics: implications in hypertension research. Hypertension 2002; 39:310-315.
-
(2002)
Hypertension
, vol.39
, pp. 310-315
-
-
Glueck, S.B.1
Dzau, V.J.2
-
23
-
-
0037219664
-
Gene expression profiling in hypertension research: A critical perspective
-
Pravenec M, Wallace C, Aitman TJ, Kurtz TW. Gene expression profiling in hypertension research: a critical perspective. Hypertension 2003; 41:3-8.
-
(2003)
Hypertension
, vol.41
, pp. 3-8
-
-
Pravenec, M.1
Wallace, C.2
Aitman, T.J.3
Kurtz, T.W.4
-
24
-
-
2542470632
-
Neuroendocrine transcriptome in genetic hypertension: Multiple changes in diverse adrenal physiological systems
-
Fries RS, Mahboubi P, Mahapatra NR, et al. Neuroendocrine transcriptome in genetic hypertension: multiple changes in diverse adrenal physiological systems. Hypertension 2004; 43:1301-1311.
-
(2004)
Hypertension
, vol.43
, pp. 1301-1311
-
-
Fries, R.S.1
Mahboubi, P.2
Mahapatra, N.R.3
-
25
-
-
0037338685
-
Cardiac transcriptome analysis in obesity-related hypertension
-
Philip-Couderc P, Smih F, Pelat M, et al. Cardiac transcriptome analysis in obesity-related hypertension. Hypertension 2003; 41:414-421.
-
(2003)
Hypertension
, vol.41
, pp. 414-421
-
-
Philip-Couderc, P.1
Smih, F.2
Pelat, M.3
-
26
-
-
0033676045
-
Large-scale N-ethyl-N-nitrosourea mutagenesis of mice-From phenotypes to genes
-
Rathkolb B, Fuchs E, Kolb HJ, et al. Large-scale N-ethyl-N-nitrosourea mutagenesis of mice-from phenotypes to genes. Exp Physiol 2000; 85:635-644.
-
(2000)
Exp Physiol
, vol.85
, pp. 635-644
-
-
Rathkolb, B.1
Fuchs, E.2
Kolb, H.J.3
-
27
-
-
0348184968
-
Functional genomics in rodent models of hypertension
-
McBride MW, Charchar FJ, Graham D, et al. Functional genomics in rodent models of hypertension. J Physiol 2004; 554:56-63.
-
(2004)
J Physiol
, vol.554
, pp. 56-63
-
-
McBride, M.W.1
Charchar, F.J.2
Graham, D.3
-
28
-
-
1242338846
-
Human genetics, animal models and computer simulations for studying hypertension
-
Takahashi N, Smithies O. Human genetics, animal models and computer simulations for studying hypertension. Trends Genet 2004; 20:136-145.
-
(2004)
Trends Genet
, vol.20
, pp. 136-145
-
-
Takahashi, N.1
Smithies, O.2
-
29
-
-
15444368389
-
Proteomics and hypertension
-
Thongboonkerd V, Klein JB, editors. Basel: Karger
-
Thongboonkerd V, Klein JB. Proteomics and hypertension. In: Thongboonkerd V, Klein JB, editors. Proteomics in nephrology. Basel: Karger; 2004. pp. 245-256. An oriented overview of proteomics applied to systemic hypertension. Future perspectives for this field are provided as well.
-
(2004)
Proteomics in Nephrology
, pp. 245-256
-
-
Thongboonkerd, V.1
Klein, J.B.2
-
30
-
-
0031852704
-
Effects of renovascular hypertension on myocardial protein patterns: Analysis by computer-assisted two-dimensional gel electrophoresis
-
Pleissner KP, Regitz-Zagrosek V, Krudewagen B, et al. Effects of renovascular hypertension on myocardial protein patterns: analysis by computer-assisted two-dimensional gel electrophoresis. Electrophoresis 1998; 19:2043-2050.
-
(1998)
Electrophoresis
, vol.19
, pp. 2043-2050
-
-
Pleissner, K.P.1
Regitz-Zagrosek, V.2
Krudewagen, B.3
-
31
-
-
0037144575
-
Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension
-
Thongboonkerd V, Gozal E, Sachleben LR, et al. Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension. J Biol Chem 2002; 277:34708-34716.
-
(2002)
J Biol Chem
, vol.277
, pp. 34708-34716
-
-
Thongboonkerd, V.1
Gozal, E.2
Sachleben, L.R.3
-
32
-
-
2442693174
-
Troponin T as a marker of differentiation revealed by proteomic analysis in renal arterioles
-
Pinet F, Poirier F, Fuchs S, et al. Troponin T as a marker of differentiation revealed by proteomic analysis in renal arterioles. FASEB J 2004; 18:585-586. A recent study that underscores the potential of proteomics in hypertension and vascular research.
-
(2004)
FASEB J
, vol.18
, pp. 585-586
-
-
Pinet, F.1
Poirier, F.2
Fuchs, S.3
-
33
-
-
15444380218
-
Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine
-
Fuchs D, Pascual-Teresa S, Rimbach G, et al. Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine. Eur J Nutr 2004; 22:1-10. A recent study that underscores the potential of proteomics in hypertension and vascular research.
-
(2004)
Eur J Nutr
, vol.22
, pp. 1-10
-
-
Fuchs, D.1
Pascual-Teresa, S.2
Rimbach, G.3
-
34
-
-
0036583670
-
Current developments in LC-MS for pharmaceutical analysis
-
Lim CK, Lord G. Current developments in LC-MS for pharmaceutical analysis. Biol Pharm Bull 2002; 25:547-557.
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 547-557
-
-
Lim, C.K.1
Lord, G.2
-
35
-
-
0038685771
-
Comparative biotransformation of radiolabeled [(14)C]Omapatrilat and stable-labeled [(13)C(2)]Omapatrilat after oral administration to rats, dogs, and humans
-
Iyer RA, Malhotra B, Khan S, et al. Comparative biotransformation of radiolabeled [(14)C]Omapatrilat and stable-labeled [(13)C(2)]Omapatrilat after oral administration to rats, dogs, and humans. Drug Metab Dispos 2003; 31:67-75.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 67-75
-
-
Iyer, R.A.1
Malhotra, B.2
Khan, S.3
-
36
-
-
0037278891
-
Determination of Tripamide in human urine by high-performance liquid chromatography and high-performance liquid chromatography/electrospray ionization tandem mass spectrometry
-
Kim Y, Hwang J, Kim M, Lee W. Determination of Tripamide in human urine by high-performance liquid chromatography and high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 2003; 17:301-306.
-
(2003)
Rapid Commun Mass Spectrom
, vol.17
, pp. 301-306
-
-
Kim, Y.1
Hwang, J.2
Kim, M.3
Lee, W.4
-
37
-
-
0037277063
-
Lacidipine, a potential peroxynitrite scavenger: Investigation of activity by liquid chromatography and mass spectrometry
-
Garzotti M. Lacidipine, a potential peroxynitrite scavenger: investigation of activity by liquid chromatography and mass spectrometry. Rapid Commun Mass Spectrom 2003; 17:272-278.
-
(2003)
Rapid Commun Mass Spectrom
, vol.17
, pp. 272-278
-
-
Garzotti, M.1
-
38
-
-
33745208159
-
Proteomics and drug discovery
-
Thongboonkerd V, Klein JB, editors. Basel: Karger
-
Jain KK. Proteomics and drug discovery. In: Thongboonkerd V, Klein JB, editors. Proteomics in nephrology. Basel: Karger; 2004. pp. 308-327.
-
(2004)
Proteomics in Nephrology
, pp. 308-327
-
-
Jain, K.K.1
-
39
-
-
0036190169
-
Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension
-
Chapman AB, Schwartz GL, Boerwinkle E, Turner ST. Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension. Kidney Int 2002; 61:1047-1055.
-
(2002)
Kidney Int
, vol.61
, pp. 1047-1055
-
-
Chapman, A.B.1
Schwartz, G.L.2
Boerwinkle, E.3
Turner, S.T.4
-
40
-
-
0842328714
-
Trends in pharmacogenomics of drugs acting on hypertension
-
Trotta R, Donati MB, Iacoviello L. Trends in pharmacogenomics of drugs acting on hypertension. Pharmacol Res 2004; 49:351-356.
-
(2004)
Pharmacol Res
, vol.49
, pp. 351-356
-
-
Trotta, R.1
Donati, M.B.2
Iacoviello, L.3
-
41
-
-
0037228801
-
Pharmacogenomics of hypertension
-
Cadman PE, O'Connor DT. Pharmacogenomics of hypertension. Curr Opin Nephrol Hypertens 2003; 12:61-70. This review provides an overview and basic concepts of pharmacogenomics applied to pharmacokinetics and pharmacodynamics.
-
(2003)
Curr Opin Nephrol Hypertens
, vol.12
, pp. 61-70
-
-
Cadman, P.E.1
O'Connor, D.T.2
-
42
-
-
2342630549
-
Primer on medical genomics. Part XIV: Introduction to systems biology - A new approach to understanding disease and treatment
-
Morel NM, Holland JM, van der GJ, et al. Primer on medical genomics. Part XIV: Introduction to systems biology - a new approach to understanding disease and treatment. Mayo Clin Proc 2004; 79:651-658. An excellent overview that provides basic concepts of systems biology for medical diseases.
-
(2004)
Mayo Clin Proc
, vol.79
, pp. 651-658
-
-
Morel, N.M.1
Holland, J.M.2
Van Der, G.J.3
-
43
-
-
0141561891
-
Integrating 'omic' information: A bridge between genomics and systems biology
-
Ge H, Walhout AJ, Vidal M. Integrating 'omic' information: a bridge between genomics and systems biology. Trends Genet 2003; 19:551-560. This paper provides an excellent overview, as well as examples of integrative omics and its application to systems biology.
-
(2003)
Trends Genet
, vol.19
, pp. 551-560
-
-
Ge, H.1
Walhout, A.J.2
Vidal, M.3
-
44
-
-
4644335402
-
Systems biology, proteomics, and the future of health care: Toward predictive, preventative, and personalized medicine
-
Weston AD, Hood L. Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine. J Proteome Res 2004; 3:179-196. An elegant discussion of systems biology and the future of health care. Not only basic concepts, but also some results of systems biology are discussed.
-
(2004)
J Proteome Res
, vol.3
, pp. 179-196
-
-
Weston, A.D.1
Hood, L.2
-
45
-
-
11144355343
-
Integrative biological analysis of the APOE*3-leiden transgenic mouse
-
Clish CB, Davidov E, Oresic M, et al. Integrative biological analysis of the APOE*3-leiden transgenic mouse. OMICS 2004; 8:3-13. The first-ever systems biology applied to mammalian diseases. The authors have proposed a model of the interaction network of genes, transcripts and proteins identified in this study.
-
(2004)
OMICS
, vol.8
, pp. 3-13
-
-
Clish, C.B.1
Davidov, E.2
Oresic, M.3
|