Detection of K-ras gene mutation in fecal samples from elderly large intestinal cancer patients and its diagnostic significance

World Journal of Gastroenterology

Volumn 10, Issue 5, 2004, Pages 743-746

  Wan, Jun ^a   Zhang, Zi Qi ^a   You, Wei Di ^a   Sun, Hua Kui ^a   Zhang, Jian Ping ^a   Wang, Ya Hong ^a   Fu, Yong He ^a  

^a GENERAL HOSPITAL OF PEOPLE'S LIBERATION ARMY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; K RAS PROTEIN;

AGED; ALLELE; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CODON; COLON POLYPOSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA EXTRACTION; EARLY DIAGNOSIS; ELDERLY CARE; FECES ANALYSIS; FEMALE; GENE IDENTIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; LARGE INTESTINE CANCER; MALE; NON INVASIVE MEASUREMENT; POLYMERASE CHAIN REACTION;

EID: 1542790164     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i5.743     Document Type: Article

References (31)

1. Wan J, Zhang ZQ, Zhu C, Wang MW, Zhao DH, Fu YH, Zhang JP, Wang YH, Wu BY. Colonoscopic screening and follow-up for colorectal cancer in the elderly. World J Gastroenterol 2002; 8: 267-269
2. Pignone M, Rich M, Teutsch SM, Berg AO, Lohr KN. Screening for colorectal cancer in adults at average risk: A summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2002; 137: 132-141
3. Xiang DN, Xiang P, Zheng SB, Cao XY, Wang GS. Diagnostic value of colonofibroscope in 1507 elderly patients of lower gastrointestinal bleeding. Laonian Yixue Yu Baojian 2002; 8: 35-36
4. Atkin W. Options for screening for colorectal cancer. Scand J Gastroenterol Suppl 2003; 237: 13-16
5. Meng W, Li SR, Li L. Effect of the combinated sequent program for screening colorectal carcinoma. Linchuang Xiaohuabin Zazhi 2000; 11: 157-158
6. Lou CY, Li SY, Zhu XG. The detection of the rearrangements of bcl-2 gene in the cancer tissues and stool of the patients with colorectal carcinoma by semi-nest PCR. Zhonghua Shiyan Waike Zazhi 1999; 16: 197-198
7. Fan RY, Li SR, Wu ZT . The detection of K-ras mutations in stools and tissue samples from patients with colorectal cancer. Zhonghua Xiaohua Zazhi 2001; 21: 445-446
8. Fan RY, Li SR, Wu X, Wu ZT, Chen ZM, Deng YJ, Cao JB, Zhang HG. The expression of P53 in shedding cells from patients with colorectal cancer. Shijie Huaren Xiaohua Zazhi 2000; 8: 814-815
9. Mandel JS, Church TR, Bond JH, Ederer F, Geisser MS, Mongin SJ, Snover DC, Schuman LM. The effect of fecal occult-blood screening on the incidence of colorectal cancer. N Engl J Med 2000; 343: 1603-1607
10. Ito S, Hibi K, Nakayama H, Kodera Y, Ito K, Akiyama S, Nakao A. Detection of tumor DNA in serum of colorectal cancer patients. Jpn J Cancer Res 2002; 93: 1266-1269
11. Smith-Ravin J, England J, Talbot IC, Bodmer W. Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients. Gut 1995; 36: 81-86
12. Ratto C, Flamini G, Sofo L, Nucera P, Ippoliti M, Curigliano G, Ferretti G, Sgambato A, Merico M, Doglietto GB, Cittadini A, Crucitti F. Detection of oncogene mutation from neoplastic colonic cells exfoliated in feces. Dis Colon Rectum 1996; 39: 1238-1244
13. Sidransky D, Tokino T, Hamilton SR, Kinzler KW, Levin B, Frost P, Vogelstein B. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.Science 1992; 256: 102-105
14. Villa E, Dugani A, Rebecchi AM, Vignoli A, Grottola A, Buttafoco P, Losi L, Perini M, Trande P, Merighi A, Lerose R, Manenti F. Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool. Gastroenterology 1996; 110: 1346-1353
15. Tagore KS, Lawson MJ, Yucaitis JA, Gage R, Orr T, Shuber AP, Ross ME. Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia. Clin Colorectal Cancer 2003; 3: 47-53
16. Ito Y, Kobayashi S, Taniguchi T, Kainuma O, Hara T, Ochiai T. Frequent detection of K-ras mutation in stool samples of colorectal carcinoma patients after improved DNA extraction: Comparison with tissue samples. Int J Oncol 2002; 20: 1263-1268
17. Berndt C, Haubold K, Wenger F, Brux B, Muller J, Bendzko P, Hillebrand T, Kottgen E, Zanow J. K-ras mutations in stools and tissue samples from patients with malignant and nonmalignant pancreatic diseases. Clin Chem 1998; 44: 2103-2107
18. Okulczyk B, Piotrowski Z, Kovalchuk O, Niklinski J, Chyczewski L. Evaluation of K-RAS gene in colorectal cancer. Folia Histochem Cytobiol 2003; 41: 97-100
19. van Engeland M, Roemen GM, Brink M, Pachen MM, Weijenberg MP, de-Bruine AP, Arends JW, van den Brandt PA, de Goeij AF, Herman JG. K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 2002; 21: 3792-3795
20. Kislitsin D, Lerner A, Rennert G, Lev Z. K-ras mutations in sporadic colorectal tumors in Israel: Unusual high frequency of codon 13 mutations and evidence for nonhomogeneous representation of mutation subtypes. Dig Dis Sci 2002; 47: 1073-1079
21. Xiao SX, Xu AM, Wang DB, Wu L, Liu HP, Zeng B. The detection of codon 12 mutations of K-ras gene in feces by nested PCR-RFLP. Zhonguo Shengwu Zhipin Zazhi 1998; 11: 103-105
22. Hermsen M, Postma C, Baak J, Weiss M, Rapallo A, Sciutto A, Roemen G, Arends JW, Williams R, Giaretti W, De Goeij A, Meijer G. Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology 2002; 123: 1109-1119
23. Scott N, Bell SM, Sagar P, Blair GE, Dixon MF, Quirke P. p53 expression and K-ras mutation in colorectal adenomas. Gut 1993; 34: 62162-62164
24. Blum HE. Colorectal cancer: Future population screening for early colorectal cancer. Eur J Cancer 1995; 31A: 1369-1672
25. Hosaka S, Aoki Y, Akamatsu T, Nakamura N, Hosaka N, Kiyosawa K. Detection of genetic alterations in the p53 suppressor gene and the K-ras oncogene among different grades of dysplasia in patients with colorectal adenomas. Cancer 2002; 94: 219-227
26. Rashid A, Houlihan PS, Booker S, Petersen GM, Giardiello FM, Hamilton SR. Phenotypic and molecular characteristics of hyperplastic polyposis. Gastroenterology 2000; 119: 323-332
27. Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I. APC mutations are sufficient for the growth of early colorectal adenomas. Proc Natl Acad Sci U S A 2000; 97: 2225-2228
28. Rashid A, Zahurak M, Goodman SN, Hamilton SR. Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas. Gut 1999; 44: 826-833
29. Glarakis IS, Savva S, Spandidos DA. Activation of the ras genes in malignant and premalignant colorectal tumors. Oncol Rep 1998, 5: 1451-1454
30. Nishikawa T, Maemura K, Hirata I, Matsuse R, Morikawa H, Toshina K, Murano M, Hashimoto K, Nakagawa Y, Saitoh O, Uchida K, Katsu K. A simple method of detecting K-ras point mutations in stool samples for colorectal cancer screening using one-step polymerase chain reaction/restriction fragment length polymorphism analysis. Clin Chim Acta 2002; 318: 107-112
31. Prix L, Uciechowski P, Bockmann B, Giesing M, Schuetz AJ. Diagnostic biochip array for fast and sensitive detection of K-ras mutations in stool. Clin Chem 2002; 48: 428-435