메뉴 건너뛰기




Volumn 5, Issue 6, 1998, Pages 1451-1454

Activation of the ras genes in malignant and premalignant colorectal tumors

Author keywords

Colon adenomas; Colon cancer; H ras; K ras; N ras; PCR RFLP

Indexed keywords

ARTICLE; CODON; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOGENESIS; COLORECTAL CANCER; COLORECTAL TUMOR; DISEASE ASSOCIATION; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; ONCOGENE RAS; POINT MUTATION; PRECANCER; PRIORITY JOURNAL; SEX DIFFERENCE;

EID: 0031690152     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.5.6.1451     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER and Voselstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Voselstein, B.2
  • 2
    • 0026648941 scopus 로고
    • Genetic alterations in the adenomacarcinoma sequence
    • Cho KR and Vogelstein B: Genetic alterations in the adenomacarcinoma sequence. Cancer 70 (Suppl): 1727-1731, 1992.
    • (1992) Cancer , vol.70 , Issue.SUPPL. , pp. 1727-1731
    • Cho, K.R.1    Vogelstein, B.2
  • 3
    • 1442341655 scopus 로고
    • Plenum Press, New York, London
    • Spandidos DA (ed.): Ras oncogenes. Plenum Press, New York, London, pp 1-323, 1989.
    • (1989) Ras Oncogenes , pp. 1-323
    • Spandidos, D.A.1
  • 4
    • 0029022018 scopus 로고
    • Mutations of ras genes in human tumors
    • Kiaris H and Spandidos DA: Mutations of ras genes in human tumors. Int J Oncol 7: 413-421, 1995.
    • (1995) Int J Oncol , vol.7 , pp. 413-421
    • Kiaris, H.1    Spandidos, D.A.2
  • 5
    • 0027428346 scopus 로고
    • Relative expression of wild-type and activated Ki-ras2 oncogene in colorectal carcinomas
    • Kotsinas A, Spandidos DA, Romanowski P and Wyllie AH: Relative expression of wild-type and activated Ki-ras2 oncogene in colorectal carcinomas. Int J Oncol 3: 841-845, 1993.
    • (1993) Int J Oncol , vol.3 , pp. 841-845
    • Kotsinas, A.1    Spandidos, D.A.2    Romanowski, P.3    Wyllie, A.H.4
  • 8
    • 0028028621 scopus 로고
    • Activating mutations in K-ras gene in ulcerative colitis and Crohn's disease
    • Spandidos DA, Kiaris H, Lioudaki E and Manousos ON: Activating mutations in K-ras gene in ulcerative colitis and Crohn's disease. Oncol Rep 1: 547-549, 1994.
    • (1994) Oncol Rep , vol.1 , pp. 547-549
    • Spandidos, D.A.1    Kiaris, H.2    Lioudaki, E.3    Manousos, O.N.4
  • 9
    • 0342819718 scopus 로고
    • Mutations in KRAS2 oncogene during progressive states of human colon carcinoma
    • Burmer GC and Loeb LA: Mutations in KRAS2 oncogene during progressive states of human colon carcinoma. Proc Natl Acad Sci USA 86: 2403-2407, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2403-2407
    • Burmer, G.C.1    Loeb, L.A.2
  • 14
    • 0028265866 scopus 로고
    • Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas
    • Yamagata S, Muto T, Uchida Y, Masaki T, Sawada T, Tsuno N and Hirooka T: Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas. Jpn J Cancer Res 85: 147-151, 1994.
    • (1994) Jpn J Cancer Res , vol.85 , pp. 147-151
    • Yamagata, S.1    Muto, T.2    Uchida, Y.3    Masaki, T.4    Sawada, T.5    Tsuno, N.6    Hirooka, T.7
  • 15
    • 0029129117 scopus 로고
    • Adenoma-carcinoma sequence of colorectum. Prevalence of K-ras gene mutation in adenomas with increasing degree of dysplasia and aneuploidy
    • Ranaldi R, Gioacchini AM, Manzin A, Clementi M, Paolucci M and Bearzi I: Adenoma-carcinoma sequence of colorectum. Prevalence of K-ras gene mutation in adenomas with increasing degree of dysplasia and aneuploidy. Diasn Mol Pathol 4: 198-202, 1995.
    • (1995) Diasn Mol Pathol , vol.4 , pp. 198-202
    • Ranaldi, R.1    Gioacchini, A.M.2    Manzin, A.3    Clementi, M.4    Paolucci, M.5    Bearzi, I.6
  • 16
    • 0027212026 scopus 로고
    • Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia
    • Urosevic N, Krtolica K, Skaro-Milic A, Knezevic-Usaj S and Dujic A: Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia. Int J Cancer 54: 249-254, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 249-254
    • Urosevic, N.1    Krtolica, K.2    Skaro-Milic, A.3    Knezevic-Usaj, S.4    Dujic, A.5
  • 19
    • 0026504414 scopus 로고
    • Effect of dietary fiber on colonic bacterial enzymes and bile acids in relation to colon cancer
    • Reddy BS, Engel A, Simi B and Goldman M: Effect of dietary fiber on colonic bacterial enzymes and bile acids in relation to colon cancer. Gastroenterology 102: 1475-1482, 1992.
    • (1992) Gastroenterology , vol.102 , pp. 1475-1482
    • Reddy, B.S.1    Engel, A.2    Simi, B.3    Goldman, M.4
  • 20
    • 0021965887 scopus 로고
    • Host factors in carcinogenesis: Certain bile-acid metabolic profiles that selectively increase the risk of proximal colon cancer
    • McMichael AJ and Potter JD: Host factors in carcinogenesis: certain bile-acid metabolic profiles that selectively increase the risk of proximal colon cancer. J Natl Cancer Inst 75: 185-191, 1985.
    • (1985) J Natl Cancer Inst , vol.75 , pp. 185-191
    • McMichael, A.J.1    Potter, J.D.2
  • 21
    • 0024312892 scopus 로고
    • Rapid detection of ras oncogenes in human tumors: Applications to colon, esophageal, and gastric cancer
    • Jiang W, Kahn SM, Guillem JG, Lu SH and Weinstein IB: Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. Oncogene 4: 923-928, 1989.
    • (1989) Oncogene , vol.4 , pp. 923-928
    • Jiang, W.1    Kahn, S.M.2    Guillem, J.G.3    Lu, S.H.4    Weinstein, I.B.5
  • 22
    • 0029151445 scopus 로고
    • Ras oncogene activation in benign and malignant colorectal cancer
    • Spandidos DA, Glarakis IS, Kotsinas A, Ergazaki M and Kiaris H: Ras oncogene activation in benign and malignant colorectal cancer. Tumori 81 (Suppl): 7-11, 1995.
    • (1995) Tumori , vol.81 , Issue.SUPPL. , pp. 7-11
    • Spandidos, D.A.1    Glarakis, I.S.2    Kotsinas, A.3    Ergazaki, M.4    Kiaris, H.5
  • 23
    • 0021234673 scopus 로고
    • Elevated expression of human ras oncogene family in premalignant and malignant tumours of the colorectum
    • Spandidos DA and Kerr IB: Elevated expression of human ras oncogene family in premalignant and malignant tumours of the colorectum. Br J Cancer 49: 681-688, 1984.
    • (1984) Br J Cancer , vol.49 , pp. 681-688
    • Spandidos, D.A.1    Kerr, I.B.2
  • 25
    • 0028296368 scopus 로고
    • Non-involvement of ras mutations in flat colorectal adenomas and adenocarcinomas
    • Fujimori T, Satonaka K, Yamamura-lhel Y, Nagasako K and Maeda S: Non-involvement of ras mutations in flat colorectal adenomas and adenocarcinomas. Int J Cancer 54: 51-55, 1994.
    • (1994) Int J Cancer , vol.54 , pp. 51-55
    • Fujimori, T.1    Satonaka, K.2    Yamamura-lhel, Y.3    Nagasako, K.4    Maeda, S.5
  • 26
    • 0027196626 scopus 로고
    • Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas
    • Shibata D, Schaeffer J, Li ZH, Capella G and Perucho M: Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J Natl Cancer Inst 85: 1058-1063, 1993.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1058-1063
    • Shibata, D.1    Schaeffer, J.2    Li, Z.H.3    Capella, G.4    Perucho, M.5
  • 27
    • 0025687278 scopus 로고
    • Relation of meat, fat and fiber intake to the risk of colon cancer in a prospective study among women
    • Willett WC, Stampfer MJ, Colditz GA, Rosner BA and Speizer FE: Relation of meat, fat and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 323: 1664-1672, 1990.
    • (1990) N Engl J Med , vol.323 , pp. 1664-1672
    • Willett, W.C.1    Stampfer, M.J.2    Colditz, G.A.3    Rosner, B.A.4    Speizer, F.E.5
  • 28
    • 0027500498 scopus 로고
    • Sex differences in colonie function: A randomized trial
    • Lampe JW, Fredstrom SB, Slavin JL and Potter JD: Sex differences in colonie function: a randomized trial. Gut 34: 531-536, 1993.
    • (1993) Gut , vol.34 , pp. 531-536
    • Lampe, J.W.1    Fredstrom, S.B.2    Slavin, J.L.3    Potter, J.D.4
  • 30
    • 84970398577 scopus 로고
    • The polyp-cancer sequence in the large bowel
    • Morson BC: The polyp-cancer sequence in the large bowel. Proc R Sos Med 67: 451-457, 1974.
    • (1974) Proc R Sos Med , vol.67 , pp. 451-457
    • Morson, B.C.1
  • 31
    • 0026823753 scopus 로고
    • Lack of ras mutations and prediction of long-term survival in carcinoma of the colon
    • Halter SA, Webb L and Rose J: Lack of ras mutations and prediction of long-term survival in carcinoma of the colon. Mod Pathol 5: 131-134, 1992.
    • (1992) Mod Pathol , vol.5 , pp. 131-134
    • Halter, S.A.1    Webb, L.2    Rose, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.