Detection of oncogene mutation from neoplastic colonic cells exfoliated in feces

Diseases of the Colon and Rectum

Volumn 39, Issue 11, 1996, Pages 1238-1244

  Ratto, Carlo ^a   Flamini, Giovanna ^b   Sofo, Luigi ^a   Nucera, Paolo ^a   Ippoliti, Massimo ^a   Curigliano, Giuseppe ^b   Ferretti, Gianluigi ^b   Sgambato, Alessandro ^b   Merico, Marta ^a   Doglietto, Giovanni Battista ^a   Cittadini, Achille ^b   Crucitti, Francesco ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b Ctro di Ric Oncologiche G   (Italy)

Author keywords

Colorectal neoplasms; Early diagnosis; Gene mutations; Genetics; K ras; polymerase chain reaction

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CYTODIAGNOSIS; CARCINOMA IN SITU; CLINICAL ARTICLE; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; COLON TUMOR; COLORECTAL CANCER; COLORECTAL CARCINOMA; EARLY DIAGNOSIS; FECES; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MALE;

EID: 10544229336     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02055116     Document Type: Article

References (22)

1. Boring CC, Squire TS, Tong T. Cancer statistics. CA Cancer J Clin 1992;42:19-38.
2. Ransohoff DF, Lang CA. Screening for colorectal cancer. N Engl J Med 1991;325:37-41.
3. Reddy BS, Engel A, Simi B, Goldman M. Effect of dietary fibre on colonic bacterial enzymes and bile acids in relation to colon cancer. Gastroenterology 1992;102:1475-82.
4. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
5. Aaltonen AA, Peltomaki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993;260:812-6.
6. Sidransky D, Von Eschenbach A, Tsai YC, et al. Identification of p53 gene mutations in bladder cancers and urine samples. Science 1991;252:706-9.
7. Sidransky D, Tokino T, Hamilton SR, et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumor. Science 1992;256:102-5.
8. Mao L, Hruban RH, Boyle JO, Tockman M, Sidransky D. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res 1994;54:1634-7.
9. Tada M, Omata M, Kawai S, et al. Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res 1993;53:2472-4.
10. Goelz SE, Hamilton SR, Vogelstein B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem Biophys Res Commun 1985;130:118-26.
11. Jiang W, Kahn SM, Guillem JG, Lu SH, Weinstein B. Rapid detection of ras oncogenes in human tumors: application to colon, esophageal and gastric cancer. Oncogene 1989;4:923-8.
12. Mehl LE. A mathematical computer stimulation model for the development of colonic polyps and colon cancer. J Surg Oncol 1991;47:243-52.
13. Tribukait B, Hammerberg C, Rubio C. Ploidy and proliferation patterns in colo-rectal adenocarcinomas related to Dukes' classification and to histopathological differentiation: a flow-cytometric DNA study. Acta Pathol Microbiol Immunol Scand [A] 1983;91:89-95.
14. Burmer GC, Rabinovitch PS, Loeb LA. Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing. Cancer Res 1989;93:2141-6.
15. Burmer GC, Rabinovitch PS, Loeb LA. Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinoma, carcinomas arising in ulcerative colitis, and pancreatic adenocarcinoma. Environ Health Perspect 1991;93:27-31.
16. Capella G, Cronauer-Mitra S, Peinado MA, Perucho M. Frequency and spectrum of mutations at codon 12 and 13 of the c-K-ras gene in human tumors. Environ Health Perspect 1991;93:125-31.
17. Bos JL, Fearon ER, Hamilton SR, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-7.
18. Forrester K, Almoguera C, Han K, Grizzle W, Perucho M. Detection of high incidence of K-ras oncogenes during human colorectal tumorigenesis. Nature 1987;327:298-303.
19. Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal tumor development. N Engl J Med 1988;319:525-31.
20. Hamilton SR. Molecular genetics of colorectal carcinoma. Cancer 1992;70:1216-21.
21. Barbacid M. Ras genes. Annu Rev Biochem 1987;56:779-827.
22. Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.