-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362: 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
2
-
-
0029966363
-
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
-
Tu PH, Raju P, Robinson KA, Gurney ME, Trojanowski JQ, Lee VM. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. USA 1996; 93: 3155-3160.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3155-3160
-
-
Tu, P.H.1
Raju, P.2
Robinson, K.A.3
Gurney, M.E.4
Trojanowski, J.Q.5
Lee, V.M.6
-
3
-
-
0030690490
-
The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies
-
Gurney ME. The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies. J. Neurol. Sci. 1997; 152:S67-S73.
-
(1997)
J. Neurol. Sci.
, vol.152
-
-
Gurney, M.E.1
-
5
-
-
0032223786
-
Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models
-
Wong PC, Borchelt DR, Lee MK, Pardo CA, Thinakaran G, Martin LJ, Sisodia SS, Price DL. Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models. Adv. Exp. Med. Biol. 1998; 446: 145-159.
-
(1998)
Adv. Exp. Med. Biol.
, vol.446
, pp. 145-159
-
-
Wong, P.C.1
Borchelt, D.R.2
Lee, M.K.3
Pardo, C.A.4
Thinakaran, G.5
Martin, L.J.6
Sisodia, S.S.7
Price, D.L.8
-
6
-
-
10244256425
-
Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease
-
Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology 1996; 47: S54-S61.
-
(1996)
Neurology
, vol.47
-
-
Cleveland, D.W.1
Bruijn, L.I.2
Wong, P.C.3
Marszalek, J.R.4
Vechio, J.D.5
Lee, M.K.6
Xu, X.S.7
Borchelt, D.R.8
Sisodia, S.S.9
Price, D.L.10
-
7
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
-
Estevez AG, Crow JP, Sampson JB, Reiter C, Zhuang Y, Richardson GJ, Tarpey MM, Barbeito L, Beckman JS. Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science 1999; 286: 2498-2500.
-
(1999)
Science
, vol.286
, pp. 2498-2500
-
-
Estevez, A.G.1
Crow, J.P.2
Sampson, J.B.3
Reiter, C.4
Zhuang, Y.5
Richardson, G.J.6
Tarpey, M.M.7
Barbeito, L.8
Beckman, J.S.9
-
8
-
-
0034696741
-
Toxicity of ALS-linked SOD1 mutants
-
Williamson TL, Corson LB, Huang L, Burlingame A, Liu J, Bruijn LI, Cleveland DW. Toxicity of ALS-linked SOD1 mutants. Science 2000; 288: 399.
-
(2000)
Science
, vol.288
, pp. 399
-
-
Williamson, T.L.1
Corson, L.B.2
Huang, L.3
Burlingame, A.4
Liu, J.5
Bruijn, L.I.6
Cleveland, D.W.7
-
9
-
-
0035331840
-
MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images
-
Hecht MJ, Fellner F, Fellner C, Hilz MJ, Heuss D, Neundorfer B. MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images. J. Neurol. Sci. 2001; 186: 37-44.
-
(2001)
J. Neurol. Sci.
, vol.186
, pp. 37-44
-
-
Hecht, M.J.1
Fellner, F.2
Fellner, C.3
Hilz, M.J.4
Heuss, D.5
Neundorfer, B.6
-
11
-
-
0036106207
-
Magnetic resonance imaging in amyotrophic lateral sclerosis
-
Basak M, Erturk M, Oflazoglu B, Ozel A, Yildiz GB, Forta H. Magnetic resonance imaging in amyotrophic lateral sclerosis. Acta Neurol. Scand. 2002; 105: 395-399.
-
(2002)
Acta Neurol. Scand.
, vol.105
, pp. 395-399
-
-
Basak, M.1
Erturk, M.2
Oflazoglu, B.3
Ozel, A.4
Yildiz, G.B.5
Forta, H.6
-
12
-
-
0035886436
-
Imaging and neurochemical markers for diagnosis and disease progression in ALS
-
Karitzky J, Ludolph AC. Imaging and neurochemical markers for diagnosis and disease progression in ALS. J. Neurol. Sci. 2001; 191: 35-41.
-
(2001)
J. Neurol. Sci.
, vol.191
, pp. 35-41
-
-
Karitzky, J.1
Ludolph, A.C.2
-
13
-
-
0035856427
-
Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS
-
Ellis CM, Suckling J, Amaro E Jr, Bullmore ET, Simmons A, Williams SC, Leigh PN. Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS. Neurology 2001; 57: 1571-1578.
-
(2001)
Neurology
, vol.57
, pp. 1571-1578
-
-
Ellis, C.M.1
Suckling, J.2
Amaro Jr., E.3
Bullmore, E.T.4
Simmons, A.5
Williams, S.C.6
Leigh, P.N.7
-
14
-
-
0036252299
-
Pattern of cortical reorganization in amyotrophic lateral sclerosis: A functional magnetic resonance imaging study
-
Konrad C, Henningsen H, Bremer J, Mock B, Deppe M, Buchinger C, Turski P, Knecht S, Brooks B. Pattern of cortical reorganization in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Exp. Brain Res. 2002; 143: 51-56.
-
(2002)
Exp. Brain Res.
, vol.143
, pp. 51-56
-
-
Konrad, C.1
Henningsen, H.2
Bremer, J.3
Mock, B.4
Deppe, M.5
Buchinger, C.6
Turski, P.7
Knecht, S.8
Brooks, B.9
-
15
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi P, Ferrante RJ, Matthews RT, Bogdanov MB, Klein AM, Andreassen OA, Mueller G, Wermer M, Kaddurah-Daouk R, Beal MF. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat. Med. 1999; 5: 347-350.
-
(1999)
Nat. Med.
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
16
-
-
0034802145
-
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis
-
Canton T, Bohme GA, Boireau A, Bordier F, Mignani S, Jimonet P, Jahn G, Alavijeh M, Stygall J, Roberts S, Brealey C, Vuilhorgne M, Debono MW, Le Guern S, Laville M, Briet D, Roux M, Stutzmann JM, Pratt J. RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis. J. Pharmac. Exp. Ther. 2001; 299: 314-322.
-
(2001)
J. Pharmac. Exp. Ther.
, vol.299
, pp. 314-322
-
-
Canton, T.1
Bohme, G.A.2
Boireau, A.3
Bordier, F.4
Mignani, S.5
Jimonet, P.6
Jahn, G.7
Alavijeh, M.8
Stygall, J.9
Roberts, S.10
Brealey, C.11
Vuilhorgne, M.12
Debono, M.W.13
Le Guern, S.14
Laville, M.15
Briet, D.16
Roux, M.17
Stutzmann, J.M.18
Pratt, J.19
-
17
-
-
0031014470
-
Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis
-
Azzouz M, Leclerc N, Gurney M, Warter JM, Poindron P, Borg J. Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis. Muscle Nerve 1997; 20: 45-51.
-
(1997)
Muscle Nerve
, vol.20
, pp. 45-51
-
-
Azzouz, M.1
Leclerc, N.2
Gurney, M.3
Warter, J.M.4
Poindron, P.5
Borg, J.6
-
18
-
-
0033953140
-
Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis
-
Kong J, Xu Z. Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis. Neurosci. Lett. 2000; 281: 72-74.
-
(2000)
Neurosci. Lett.
, vol.281
, pp. 72-74
-
-
Kong, J.1
Xu, Z.2
-
19
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
Kong J, Xu Z. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J. Neurosci. 1998; 18: 3241-3250.
-
(1998)
J. Neurosci.
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
20
-
-
0037380924
-
Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis
-
Wu AS, Kiaei M, Aguirre N, Crow JP, Calingasan NY, Browne SE, Beal MF. Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis. J. Neurochem. 2003; 85: 142-150.
-
(2003)
J. Neurochem.
, vol.85
, pp. 142-150
-
-
Wu, A.S.1
Kiaei, M.2
Aguirre, N.3
Crow, J.P.4
Calingasan, N.Y.5
Browne, S.E.6
Beal, M.F.7
-
21
-
-
0030862630
-
The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Hottinger AF, Fine EG, Gurney ME, Zurn AD, Aebischer P. The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. Eur. J. Neurosci. 1997; 9: 1548-1551.
-
(1997)
Eur. J. Neurosci.
, vol.9
, pp. 1548-1551
-
-
Hottinger, A.F.1
Fine, E.G.2
Gurney, M.E.3
Zurn, A.D.4
Aebischer, P.5
-
22
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995; 14: 1105-1116.
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
23
-
-
0027946294
-
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
-
Dal Canto MC, Gurney ME. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 1994; 145: 1271-1279.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1271-1279
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
24
-
-
0036830072
-
Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
-
Jung C, Higgins CM, Xu Z. Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis. J. Neurochem. 2002; 83: 535-545.
-
(2002)
J. Neurochem.
, vol.83
, pp. 535-545
-
-
Jung, C.1
Higgins, C.M.2
Xu, Z.3
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