Induction of mitochondrion-mediated apoptosis of CHO cells by tripchloro- lide

Cell Research

Volumn 13, Issue 4, 2003, Pages 295-300

  Ren, Yan ^a   Xiong, Lei ^a   Wu, Jia Rui ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Apoptosis; CHO cell; Mitochondrial pathway

Indexed keywords

CRICETULUS GRISEUS; TRIPTERYGIUM; TRIPTERYGIUM WILFORDII;

BAX PROTEIN, HUMAN; CYTOCHROME C; DITERPENE; HERBACEOUS AGENT; ONCOPROTEIN; PHENANTHRENE DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; TRIPCHLOROLIDE;

ANIMAL; APOPTOSIS; ARTICLE; CHO CELL; DRUG EFFECT; HAMSTER; HUMAN; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CHO CELLS; CRICETINAE; CYTOCHROMES C; DITERPENES; DRUGS, CHINESE HERBAL; HUMANS; MITOCHONDRIA; PHENANTHRENES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 1542677328     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7290174     Document Type: Article

References (27)

1. Jacobson MD, Weil M, Raff MC. Programmed Cell Death in Animal Development. Cell 1997; 88:347-54.
2. White E. Life, death and pursuit of apoptosis. Genes Dev 1996; 10:1-15.
3. Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15:2922-33.
4. Geng YJ. Molecular signal transduction in vascular cell apoptosis. Cell Res 2001; 11:253-64.
5. Chao DT, Korsmeyer SJ. Bcl-2 family: regulators of cell death. Annu Rev Immunol 1998; 16:395-419.
6. Matthew G., Heiden V, Thompson CB. Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nature Cell Biol 1999; 1:E209-16.
7. Antonsson B, Martinou J. The Bcl-2 protein family. Exp Cell Res 2000; 256:50-7.
8. Budihardho I, Oliver H, Lutter M, Xu L, Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999; 15:269-90.
9. Lu X, Ma P, Chen T et al. The isolation and structure of tripcholrolide (T4) from Tripterygium Wilfordii. Acta Academiae Medicinae Sinicae 1990; 12:157-61.
10. Qian SZ, Xu Y, Zhang JW. Recent progress in research on Tripterygium: a male antifertility plant. Contraception 1995; 51:121-9.
11. Zhang T, Chen Z, Lin C. Antineoplastic action of triptolide and its effect on the immunologic functions in mice. Acta Pharm Sinica 1981; 2:128-31.
12. Lee KY, Chang W, Qiu D, Kao PN, Rosen GD. PG490 (triptolide) cooperates with tumor necrosis factor-a to induce apoptosis in tumor cells. J Biol Chem 1999; 274:13451-5.
13. Chang W, Kang JJ, Lee K et al. Triptolide and chemotherapy cooperate in tumor cell apoptosis. J Biol Chem 2001; 276:2221-7.
14. Zhang J, Xu M. DNA fragmentation in apoptosis. Cell Res 2000; 10:205-11.
15. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184:39-51.
16. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281:1309-12.
17. Guo BC, Xu YH. Bcl-2 over-expression and activation of protein kinase C suppress the trail-induced apoptosis in Jurkat T cells. Cell Res 2001; 11:101-6.
18. Gottlieb RA, Granville DJ. Analyzing mitochondrial changes during apoptosis. Methods 2002; 26:341-7.
19. Khaled AR, Kim K, Hofmeister R, Muegge K, Durum SK. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. Proc Natl Acad Sci USA 1999; 96:14476-81.
20. Gross A, Jockel J, Wie MC, Korsmeyer SJ. Enforced dimerization of Bax results in its translocation, mitochondrail dysfunction and apoptosis. EMBO J 1998; 17:3878-85.
21. Jü gensmeier JM, Xie Z, Deveraux Q, Ellerby L, Bredesen D, Reed JC. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA 1998; 95:4997-5002.
22. Jiang MR, Li YC, Yang Y, Wu JR. c-Myc degradation induced by DNA damage results in apoptosis of CHO cells. Oncogene 2003; 22:3252-9.
23. Murphy K, Streips UN, Lock RB. Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation. J Biol Chem 2000; 275:17225-8.
24. Khaled AR, Kim K, Hofmeister R, Muegge K, Durum SK. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. Proc Natl Acad Sci USA 1999; 96:14476-81.
25. Suzuki M, Youle RJ, Tjandra N. Structure of Bax: coregulation of dimmer formation and intracellular localization. Cell 2000; 103:645-54.
26. Sundararajan R, White E. E1b 19k blocks bax oligomerization and tumor necrosis factor alpha-mediated apoptosis. J Virol 2001; 75:7506-16.
27. Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 2001; 292:727-30.