Susceptibility of oral bacteria to an antimicrobial decapeptide

Journal of Medical Microbiology

Volumn 52, Issue 12, 2003, Pages 1083-1093

  Concannon, S P ^a,d   Crowe, T D ^a   Abercrombie, J J ^a   Molina, C M ^a   Hou, P ^a   Sukumaran, D K ^b   Raj, P A ^c   Leung, K P ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c MARQUETTE UNIVERSITY   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DIMETHYL SULFOXIDE; LYSYLLYSYLVALYLVALYLPHENYLALANYLLYSYLVALYLLYSYLPHENYLALANYLLYSINE; PEPTIDE; UNCLASSIFIED DRUG; DEPSIPEPTIDE; LYSYL LYSYL VALYL VALYL PHENYLALANYL LYSYL VALYL LYSYL PHENYLALANYL LYSINE; LYSYL-LYSYL-VALYL-VALYL-PHENYLALANYL-LYSYL-VALYL-LYSYL-PHENYLALANYL-LYSINE; OLIGOPEPTIDE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ALPHA HELIX; AQUEOUS SOLUTION; ARTICLE; BACTERIAL COUNT; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; BACTERIUM; CELL DEATH; CELL MEMBRANE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DILUTION; DRUG EFFICACY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SENSITIVITY; DRUG STRUCTURE; FIBROBLAST; GINGIVA; HUMAN; HUMAN CELL; IN VITRO STUDY; LACTOBACILLUS SALIVARIUS; MAMMAL CELL; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MIMICRY; MOUTH; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SALIVA; STREPTOCOCCUS GORDONII; STREPTOCOCCUS MUTANS; STRUCTURE ANALYSIS; TEMPERATURE; TIME; DRUG EFFECT; LACTOBACILLUS; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PROTEIN CONFORMATION;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ANTI-BACTERIAL AGENTS; DEPSIPEPTIDES; HUMANS; LACTOBACILLUS; MICROBIAL SENSITIVITY TESTS; OLIGOPEPTIDES; PROTEIN CONFORMATION; SALIVA; STREPTOCOCCUS MUTANS;

EID: 1542644979     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.05286-0     Document Type: Article

References (67)

1. Bateman, A., Singh, A., Shustik, C., Mars, W. M. & Solomon, S. (1991). The isolation and identification of multiple forms of the neutrophil granule peptides from human leukemic cells. J Biol Chem 266, 7524-7530.
2. Blondelle, S. E. & Houghten, R. A. (1996). Novel antimicrobial compounds identified using synthetic combinatorial library technology. Trends Biotechnol 14, 60-65.
3. Blondelle, S. E., Takahashi, E., Weber, P. A. & Houghten, R. A. (1994). Identification of antimicrobial peptides by using combinatorial libraries made up of unnatural amino acids. Antimicrob Agents Chemother 38, 2280-2286.
4. Blondelle, S. E., Pérez-Payá, E. & Houghten, R. A. (1996a). Synthetic combinatorial libraries: novel discovery strategy for identification of antimicrobial agents. Antimicrob Agents Chemother 40, 1067-1071.
5. Blondelle, S. E., Takahashi, E., Houghten, R. A. & Pérez-Payá, E. (1996b). Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries. Biochem J 313, 141-147.
6. Boggiano, C., Reixach, N., Pinilla, C. & Blondelle, S. E. (2003). Successful identification of novel agents to control infectious diseases from screening mixture-based peptide combinatorial libraries in complex cell-based bioassays. Biopolymers 71, 103-116.
7. Boman, H. G. (1991). Antibacterial peptides: key components needed in immunity. Cell 65, 205-207.
8. Boman, H. G. (1998). Gene-encoded peptide antibiotics and the concept of innate immunity: an update review. Scand J Immunol 48, 15-25.
9. Bowden, G. H. W. (1991). Which bacteria are cariogenic in humans? In Risk Markers for Oral Diseases, vol. 1, pp. 266-286. Edited by N. W. Johnson. Cambridge, UK: Cambridge University Press.
10. Chen, J., Falla, T. J., Liu, H. & 9 other authors (2000). Development of protegrins for the treatment and prevention of oral mucositis: structure-activity relationships of synthetic protegrin analogues. Biopolymers 55, 88-98.
11. Davies, J. (1994). Inactivation of antibiotics and the dissemination of resistance genes. Science 264, 375-382.
12. Decker, T. & Lohmann-Matthes, M. L. (1988). A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J Immunol Methods 115, 61-69.
13. Dyson, H. J. & Wright, P. E. (1991). Defining solution conformations of small linear peptides. Annu Rev Biophys Biophys Chem 20, 519-538.
14. Elsbach, P. (2003). What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses? J Clin Invest 111, 1643-1645.
15. Friedrich, C., Scott, M. G. Karunaratne, N., Yan, H. & Hancock, R. E. W. (1999). Salt-resistant alpha-helical cationic antimicrobial peptides. Antimicrob Agents Chemother 43, 1542-1548.
16. Fuchs, P. C., Barry, A. L. & Brown, S. D. (1998). In vitro antimicrobial activity of MSI-78, a magainin analog. Antimicrob Agents Chemother 42, 1213-1216.
17. Gibbons, R. J. (1996). Role of adhesion in microbial colonization of host tissues: a contribution of oral microbiology. J Dent Res 75, 866-870.
18. Guthmiller, J. M., Vargas, K. G., Srikantha, R., Schomberg, L. L., Weistroffer, P. L., McCray, P. B., Jr & Tack, B. F. (2001). Susceptibilities of oral bacteria and yeast to mammalian cathelicidins. Antimicrob Agents Chemother 45, 3216-3219.
19. Hancock, R. E. W. (1997a). Antibacterial peptides and the outer membranes of Gram-negative bacilli. J Med Microbiol 46, 1-3.
20. Hancock, R. E. W. (1997b). Peptide antibiotics. Lancet 349, 418-422.
21. Hancock, R. E. W. & Lehrer, R. (1998). Cationic peptides: a new source of antibiotics. Trends Biotechnol 16, 82-88.
22. Hancock, R. E. W. & Chapple, D. S. (1999). Peptide antibiotics. Antimicrob Agents Chemother 43, 1317-1323.
23. Hancock, R. E. W. & Rozek, A. (2002). Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol Lett 206, 143-149.
24. Hancock, R. E. W., Falla, T. & Brown, M. (1995). Cationic bactericidal peptides. Adv Microb Physiol 37, 135-175.
25. Helmerhorst E. J., van't Hof, W., Veerman, E. C. I., Simoons-Smit, I. & Nieuw Amerongen, A. V. (1997). Synthetic histatin analogues with broad-spectrum antimicrobial activity. Biochem J 326, 39-45.
26. Helmerhorst E. J., Hodgson, R., van't Hof, W., Veerman, E. C. I., Allison, C. & Nieuw Amerongen, A. V. (1999). The effects of histatin-derived basic antimicrobial peptides on oral biofilms. J Dent Res 78, 1245-1250.
27. Henderson, B., Poole, S. & Wilson, M. (editors) (1998). Bacteria-Cytokine Interactions in Health and Disease. London: Portland Press.
28. Hong, S. Y., Oh, J. E., Kwon, M., Choi, M. J., Lee, J. H., Lee, B. L., Moon, H. M. & Lee, K. H. (1998). Identification and characterization of novel antimicrobial decapeptides generated by combinatorial chemistry. Antimicrob Agents Chemother 42, 2534-2541.
29. Kaiser, E., Colescott, R. L., Bossinger, C. D. & Cook, P. I. (1970). Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal Biochem 34, 595-598.
30. Kilian, M., Mikkelsen, L. & Henrichsen, J. (1989). Taxonomic study of viridans streptococci: description of Streptococcus gordonii sp. nov. and emended descriptions of Streptococcus sanguis (White and Niven 1946), Streptococcus oralis (Bridge and Sneath 1982), and Streptococcus mitis (Andrewes and Horder 1906). Int J Syst Bacteriol 39, 471-484.
31. Koczulla, A. R. & Bals, R. (2003). Antimicrobial peptides: current status and therapeutic potential. Drugs 63, 389-406.
32. Koczulla, R., von Degenfeld, G., Kupatt, C. & 17 other authors (2003). An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest 111, 1665-1672.
33. Kolenbrander, P. E. & London, J. (1992). Ecological significance of coaggregation among oral bacteria. Adv Microb Ecol 12, 183-217.
34. Kolenbrander, P. E., Ganeshkumar, N., Cassels, F. J. & Hughes, C. V. (1993). Coaggregation: specific adherence among human oral plaque bacteria. FASEB J 7, 406-413.
35. Lee, I. H., Cho, Y. & Lehrer, R. I. (1997). Effects of pH and salinity on the antimicrobial properties of clavanins. Infect Immun 65, 2898-2903.
36. Lisle, J. T., Stewart, P. S. & McFeters, G. A. (1999). Fluorescent probes applied to physiological characterization of bacterial biofilms. Methods Enzymol 310, 166-178.
37. Loesche, W. J. & Syed, S. A. (1978). Bacteriology of human experimental gingivitis: effect of plaque and gingivitis score. Infect Immun 21, 830-839.
38. MacKay, B. J., Denepitiya, L., Iacono, V. J., Krost, S. B. & Pollock, J. J. (1984). Growth-inhibitory and bactericidal effects of human parotid salivary histidine-rich polypeptides on Streptococcus mutans. Infect Immun 44, 695-701.
39. Mickels, N., McManus, C., Massaro, J. & 7 other authors (2001). Clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis. J Clin Periodontol 28, 404-410.
40. Miyasaki, K. T., Bodeau, A. L., Selsted, M. E., Ganz, T. & Lehrer, R. I. (1990). Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1. Oral Microbiol Immunol 5, 315-319.
41. Miyasaki, K. T., Iofel, R. & Lehrer, R. I. (1997). Sensitivity of periodontal pathogens to the bactericidal activity of synthetic protegrins, antibiotic peptides derived from porcine leukocytes. J Dent Res 76, 1453-1459.
42. Miyasaki, K. T., Iofel, R., Oren, A., Huynh, T. & Lehrer, R. I. (1998). Killing of Fusobacterium nucleatum, Porphyromonas gingivalis and Prevotella intermedia by protegrins. J Periodont Res 33, 91-98.
43. Mosca, D. A., Hurst, M. A., So, W., Viajar, B. S. C., Fujii, C. A. & Falla, T. J. (2000). IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis. Antimicrob Agents Chemother 44, 1803-1808.
44. Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
45. Murakami, M., Ohtake, T., Dorschner, R. A. & Gallo, R. L. (2002). Cathelicidin antimicrobial peptides are expressed in salivary glands and saliva. J Dent Res 81, 845-850.
46. Nizet, V., Ohtake, T., Lauth, X. & 7 other authors (2001). Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 414, 454-457.
47. Oh, J. E., Hong, S. Y. & Lee, K. H. (1999). Structure-activity relationship study: short antimicrobial peptides. J Pept Res 53, 41-46.
48. Pardi, A., Billeter, M. & Wuthrich, K. (1984). Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure. J Mol Biol 180, 741-751.
49. Raj, P. A., Edgerton, M. & Levine, M. J. (1990). Salivary histatin 5: dependence of sequence, chain length, and helical conformation for candidacidal activity. J Biol Chem 265, 3898-3905.
50. Raj, P. A., Marcus, E. & Edgerton, M. (1996). Delineation of an active fragment and poly(L-proline) II conformation for candidacidal activity of bactenecin 5. Biochemistry 35, 4314-4325.
51. Raj, P. A., Marcus, E. & Sukumaran, D. K. (1998). Structure of human salivary histatin 5 in aqueous and nonaqueous solutions. Biopolymers 45, 51-67.
52. Raj, P. A., Karunakaran, T. & Sukumaran, D. K. (2000a). Synthesis, microbicidal activity, and solution structure of the dodecapeptide from bovine neutrophils. Biopolymers 53, 281-292.
53. Raj, P. A., Antonyraj, K. J. & Karunakaran, T. (2000b). Large-scale synthesis and functional elements for the antimicrobial activity of defensins. Biochem J 347, 633-641.
54. Rothstein, D. M., Spacciapoli, P., Tran, L. T., Xu, T., Roberts, F. D., Dalla Serra, M., Buxton, D. K., Oppenheim, F. G. & Friden, P. (2001). Anticandida activity is retained in P-113, a 12-amino-acid fragment of histatin 5. Antimicrob Agents Chemother 45, 1367-1373.
55. Schutze, G. E., Kaplan, S. L. & Jacobs, R. F. (1994). Resistant Pneumococcus: a worldwide problem. Infection 22, 233-237.
56. Slots, J., Bragd, L., Wikström, M. & Dahlén, G. (1986). The occurrence of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius in destructive periodontal disease in adults. J Clin Periodontol 13, 570-577.
57. Socransky, S. S., Haffajee, A. D., Cugini, M. A., Smith, C. & Kent R. L., Jr (1998). Microbial complexes in subgingival plaque. J Clin Periodontol 25, 134-144.
58. Summey, D. L. & Jordan, H. V. (1974). Characterization of bacteria isolated from human root surface carious lesions. J Dent Res 53, 343-351.
59. Tamamura, H., Murakami, T., Horiuchi, S. & 7 other authors (1995). Synthesis of protegrin-related peptides and their antibacterial and antihuman immunodeficiency virus activity. Chem Pharm Bull (Tokyo) 43, 853-858.
60. Tanaka, D., Miyasaki, K. T. & Lehrer, R. I. (2000). Sensitivity of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: a cathelicidin found in human leukocytes and epithelium. Oral Microbiol Immunol 15, 226-231.
61. van Houte, J. (1994). Role of micro-organisms in caries etiology. J Dent Res 73, 672-681.
62. Wade, D., Andreu, D., Mitchell, S. A., Silveira, A. M., Boman, A., Boman, H. G. & Merrifield, R. B. (1992). Antibacterial peptides designed as analogs or hybrids of cecropins and melittin. Int J Pept Protein Res 40, 429-436.
63. Wüthrich, K. (1986). NMR of Proteins and Nucleic Acids. New York: Wiley.
64. Yeaman, M. R. & Yount, N. Y. (2003). Mechanisms of antimicrobial peptide action and resistance. Pharmacol Rev 55, 27-55.
65. Zasloff, M. (1992). Antibiotic peptides as mediators of innate immunity. Curr Opin Immunol 4, 3-7.
66. Zasloff, M. (2002). Antimicrobial peptides of multicellular organisms. Nature 415, 389-395.
67. Zhao, C., Liu, L. & Lehrer, R. I. (1994). Identification of a new member of the protegrin family by cDNA cloning. FEBS Lett 346, 285-288.