Identification of protein-protein interaction sites from docking energy landscapes

Journal of Molecular Biology

Volumn 335, Issue 3, 2004, Pages 843-865

  Fernández Recio, Juan ^a,c   Totrov, Maxim ^b   Abagyan, Ruben ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MOLSOFT LLC   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Binding site identification; Docking energy landscapes; Hot spots; ICM, internal coordinate mechanics; PDB, Protein Data Bank; PPI, protein protein interaction; Protein protein interactions; Pseudo Brownian Monte Carlo; RMSD, root mean square deviation

Indexed keywords

PROTEIN;

ARTICLE; ENERGY TRANSFER; GENE MUTATION; GENE SEQUENCE; GEOMETRY; MOLECULAR RECOGNITION; MONTE CARLO METHOD; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIMULATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; EXPERT SYSTEM; PROTEIN BINDING; VALIDATION STUDY;

BINDING SITES; COMPUTER SIMULATION; EXPERT SYSTEMS; MODELS, MOLECULAR; MONTE CARLO METHOD; PROTEIN BINDING; PROTEINS;

EID: 1542390499     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.10.069     Document Type: Article

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