The anti-inflammatory effect of leptin on experimental colitis: Involvement of endogenous glucocorticoids

Peptides

Volumn 25, Issue 1, 2004, Pages 95-104

  Çakir, Bariş ^a   Bozkurt, Ayhan ^a,b   Ercan, Feriha ^a   Yeǧen, Berrak Ç ^a  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Acetic acid colitis; ACTH; Hypothalamo pituitary adrenal axis; Myeloperoxidase activity; Water avoidance stress

Indexed keywords

ACETIC ACID; GLUCOCORTICOID; LEPTIN; MIFEPRISTONE; MYELOPEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; DECAPITATION; ENZYME ACTIVITY; EXPERIMENTAL TEST; FEMALE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INJECTION SITE; MALE; MICROSCOPY; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; STRESS;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS; COLON; DEHYDRATION; FEMALE; GLUCOCORTICOIDS; INFLAMMATION; LEPTIN; MALE; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 1542319255     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2003.11.005     Document Type: Article

References (49)

1. Anton P.A., Shanahan F. Neuroimmunomodulation in inflammatory bowel disease: how far from bench to bedside? Ann. N.Y. Acad. Sci. 840:1998;723-735.
2. Bado A., Levasseur S., Attoub S., Kermorgant S., Laigneau J.P., Bortoluzzi M.N.et al. The stomach is a source of leptin. Nature. 394:1998;790-793.
3. Barbier M., Attoub S., Joubert M., Bado A., Laboisse C., Cherbut C.et al. Proinflammatory role of leptin in experimental colitis in rats benefit of cholecystokinin-B antagonist and beta3-agonist. Life. Sci. 69(5):2001;567-580.
4. Bozkurt A., Çakir B., Ercan F., Yegen B.Ç. Anti-imflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers. Regul. Pept. 116(1-3):2003;109-118.
5. Bradley P.P., Priebat D.A., Christersen R.D., Rothstein G. Measurement of cutaneous inflammation. Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:1982;206-209.
6. Brzozowski T., Konturek P.C., Pajdo R., Kwiecien S., Ptak A., Sliwowski Z.et al. Brain-gut axis in gastroprotection by leptin and cholecystokinin against ischemia-reperfusion induced gastric lesions. J. Physiol. Pharmacol. 52(4):2001;583-602.
7. Brzozowski T., Konturek P.C., Konturek S.J., Pierzchalski P., Bielanski W., Pajdo R.et al. Central leptin and cholecystokinin in gastroprotection against ethanol induced damage. Digestion. 62:2000;126-142.
8. Buyse M., Berlioz F., Guilmeau S., Tsocas A., Voisin T., Peranzi G.et al. PepT1-mediated epithelial transport of dipeptide and cephalexin is enhanced by luminal leptin in the small intestine. J. Clin. Invest. 108:2001;1483-1494.
9. Campfield L.A., Smith F.J., Guisez Y., Devos R., Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science. 269:1995;546-549.
10. Collins S.M. Stress and the gastrointestinal tract. IV. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance. Am. J. Physiol. 280:2001;G315-G318.
11. Cronstein B.N., Kimmel S.C., Levin R.I., Martiniuk F., Weismann G.A. Mechanism for the anti-inflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 89:1992;9991-9995.
12. Elson C.O., Sartor R.B., Tennyson G.S., Riddell R.H. Experimental models of inflammatory bowel disease. Gastroenterology. 109:1995;1344-1367.
13. Faggioni R., Feingold K.R., Grunfeld C. Leptin regulation of the immune response and the immunodeficiency of malnutrition. FASEB J. 15(14):2001;2565- 2571.
14. Fantuzzi G., Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoesis. J. Leukoc. Biol. 68(4):2000;437-446.
15. Filaretova L., Tanaka A., Miyazawa T., Kato S., Takeuchi K. Mechanisms by which endogenous glucocorticoid protects against indomethacin-induced gastric injury in rats. Am. J. Physiol. 283:2002;G1082-G1089.
16. Finck B.N., Johnson R.W. Tumor necrosis factor-alpha regulates secretion of the adipocyte-derived cytokine, leptin. Microsc. Res. Tech. 50(3):2000;209-215.
17. Frederich R.C., Lollmann B., Hamann A., Napolitano-Rosen A., Kahn B.B., Lowell B.et al. Expression of ob mRNA and its encoded protein in rodents. J. Clin. Invest. 96:1995;1658-1663.
18. Glasow A, Bornstein SR. Leptin and the adrenal gland. Eur J Clin Invest 2000;Suppl 3:39-45.
19. Goldstein RA, Bowen DL, Fauci AS. Adrenal corticosteroids. In: Gallin JI, Goldstein IM, Snyderman R, editors. Inflammation: basic principles and clinical correlates. New York: Raven Press. p. 1061-81.
20. Gue M., Bonbonne C., Fioramonti J., More J., Del Rio-Lacheze L., Comera C.et al. Stress-induced enhancement of colitis in rats (1992) CRF and arginine vasopressin are not involved. Am. J. Physiol. 272:1997;G84-G91.
21. Hardwick J.C.H., Van Den Brink G.R., Offerhaus G.J., Van Deventer S.J.H., Peppelenbosch M.P. Leptin is a growth factor for colonic epithelial cells. Gastroenterology. 121:2001;79-90.
22. Houseknecht K.L., Baile C.A., Matteri R.L., Spurlock M.E. The biology of leptin: a review. J. Anim. Sci. 76:1998;1405-1420.
23. Konturek P.C., Brzozowski T., Sulekova Z., Brzozowska I., Duda A., Meixner H.et al. Role of leptin in ulcer healing. Eur. J. Pharmacol. 414(1):2001;87-97.
24. Konturek P.C., Konturek S.J., Brzozowski T., Hahn E.G. Gastroprotection and control of food intake by leptin. Comparison with cholecystokinin and prostaglandins. J. Physiol. Pharmacol. 50(1):1998;39-48.
25. Kresse A.E., Million M., Saperas E., Tache Y. Colitis induces CRF expression in hypothalamic magnocellular neurons and blunts CRF gene response to stress in rats. Am. J. Physiol. 281:2001;G1203-G1213.
26. Lofberg R. Review article: medical treatment of mild to moderately act Crohn's disease. Aliment Pharmacol. Ther. 17(2):2003;18-22.
27. MacPherson B.R., Pfeiffer C.J. Experimental production of diffuse colitis in rats. Digestion. 17:1978;135-150.
28. Masuzaki H., Ogawa Y., Sagawa N., Hosoda K., Matsumoto T., Mise H.et al. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat. Med. 3:1997;1029-1033.
29. McCafferty D.M., Wallace J.L., Sharkey K.A. Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rats. Am. J. Physiol. 35:1997;G272-G280.
30. Million M., Tache Y., Anton P. Susceptibility of Lewis and Fischer rats to stress-induced worsening of TNB-colitis: protective role of brain CRF. Am. J. Physiol. 276:1999;G1027-G1036.
31. Nowak K.W., Pierzchala-Koziec K., Tortorella C., Nussdorfer G.G., Malendowicz L.K. Effects of prolonged leptin infusion on rat pituitary-adrenocortical function. Int. J. Mol. Med. 9(1):2002;61-64.
32. Oates M., Woodside B., Walker C.D. Chronic leptin administration in developing rats reduces stress responsiveness partly through changes in maternal behaviour. Horm. Behav. 37(4):2000;366-376.
33. Oyanagi Y., Suzuki S. Vasoregulin, a glucocorticoid-inducible vascular permeability inhibitory protein. Agents Actions. 17:1985;270-277.
34. Proulx K., Clavel S., Nault G., Richard D., Walker C.D. High neonatal leptin exposure enhances brain GR expression and feedback efficacy on the adrenocortical axis of developing rats. Endocrinology. 142(11):2001;4607-4616.
35. Rivier C., Rivest S. Mechanisms mediating the effects of cytokines on neuroendocrine functions in the rat. Ciba Found. Symp. 172:1993;204-225.
36. Schleimer R.P. An overview of glucocorticoid anti-inflammatory actions. Eur. J. Clin. Pharmacol. 45:1993;S3-S7.
37. Sobhani I., Buyse M., Goiot H., Weber N., Laigneau J.P., Henin D.et al. Vagal stimulation rapidly increases leptin secretion in human stomach. Gastroenterology. 122:2002;259-263.
38. Söderholm J.D., Perdue M.H. Stress and the gastrointestinal tract. II. Stress and intestinal barrier function. Am. J. Physiol. 280:2001;G7-G13.
39. Sternberg E.M., Young W.S. III, Bernardini R., Calogero A.E., Chrousos G.P., Gold P.W.et al. A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats. Proc. Natl. Acad. Sci. U.S.A. 86:1989;4771-4775.
40. Sternberg V.I., Bouley M.G., Katz B.M., Lee K.J., Parmar S.S. Negative endocrine control system for inflammation in rats. Agents Actions. 29:1990;189-195.
41. Swain M.G., Maric M. Prevention of immune-mediated arthritis in cholestatic rats: involvement of endogenous glucocorticoids. Gastroenterology. 107:1994;1469-1474.
42. Takeuchi K., Nishiwaki H., Okada M., Niida H., Okabe S. Bilateral adrenalectomy worsens gastric mucosal lesions induced by indomethacin in the rat. Role of enhanced gastric motility. Gastroenterology. 97:1989;284-293.
43. Tartaglia L., Dembski M., Weng X., Deng N., Culpepper J., Devos R.et al. Identification and expression cloning of leptin receptor, OB-R. Cell. 83:1995;1263-1271.
44. Tjandra K., Kubes P., Rioux K., Swain M.G. Endogenous glucocorticoids inhibit neutrophil recruitment to inflammatory sites in cholestatic rats. Am. J. Physiol. 270:1996;G821-G825.
45. Trayhurn P., Hoggard N., Mercer J.G., Rayner D.V. Leptin: fundamental aspects. Int. J. Obes. Relat. Metab. Disord. 23:1999;22-28.
46. 4 synthesis. Gastroenterology. 102:1992;18-27.
47. Wang J., Liu R., Hawkins M., Barzilai N., Rosetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature. 393:1998;684-688.
48. Vainer B., Nielsen O.H. Correlation between circulating soluble ICAM-1 and prednisolone-induced amelioration of ulcerative colitis. Scand. J. Gastroenterol. 38(3):2003;283-287.
49. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature. 372:1994;425-432.