NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: Evidence for a two-site binding model

Journal of Biological Chemistry

Volumn 279, Issue 9, 2004, Pages 8441-8451

  Gao, Guanghua ^a   Prutzman, Kirk C ^a   King, Michelle L ^b   Scheswohl, Danielle M ^b   DeRose, Eugene F ^c   London, Robert E ^c   Schaller, Michael D ^b   Campbell, Sharon L ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; COMPLEXATION; CONFORMATIONS; ENZYMES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYPEPTIDES;

FOCAL ADHESIONS; TYROSINE KINASE;

BIOCHEMISTRY;

FOCAL ADHESION KINASE; PAXILLIN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ELECTRON SPIN RESONANCE; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME STRUCTURE; EXTRACELLULAR MATRIX; FOCAL ADHESION; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALORIMETRY; COMPUTER SIMULATION; CYTOSKELETAL PROTEINS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLUTATHIONE TRANSFERASE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS; PAXILLIN; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; SOFTWARE; SOLUTIONS; THERMODYNAMICS;

ANIMALIA; AVES;

EID: 1542289014     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309808200     Document Type: Article

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