Structural and enzymatic parameters that determine alkyl dehydrogenation/hydroxylation of capsaicinoids by cytochrome P450 enzymes

Drug Metabolism and Disposition

Volumn 33, Issue 4, 2005, Pages 530-536

  Reilly, Christopher A ^a   Yost, Garold S ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; CYTOCHROME P450 2C9; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DIHYDROCAPSAICIN; DRUG METABOLITE; HOMOCAPSAICIN; HOMODIHYDROCAPSAICIN; N VANILLYLCAPRAMIDE; N VANILLYLOCTANAMIDE; NONIVAMIDE; NORDIHYDROCAPSAICIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEHYDROGENATION; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; ENZYME MECHANISM; FATTY ACID METABOLISM; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; PRIORITY JOURNAL; PROTEIN INTERACTION; STEREOCHEMISTRY; TANDEM MASS SPECTROMETRY;

CAPSAICIN; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROXYLATION; MICROSOMES, LIVER; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

CAPSICUM FRUTESCENS;

EID: 15344350833     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.001214     Document Type: Article

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