3D-QSAR and preliminary evaluation of anti-inflammatory activity of series of N-pyrrolylcarboxylic acids

Farmaco

Volumn 60, Issue 3, 2005, Pages 209-218

  Lessigiarska, Iglika ^a   Nankov, Atanas ^b   Bocheva, Adriana ^c   Pajeva, Ilza ^a   Bijev, Atanas ^b  

^a BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^b UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY   (Bulgaria)

^c INSTITUTE OF PHYSIOLOGY   (Bulgaria)

Author keywords

Anti inflammatory activity; CoMFA; Pyrrole; QSAR

Indexed keywords

ANTIINFLAMMATORY AGENT; CARBOXYLIC ACID DERIVATIVE; CARRAGEENAN; CAS 53861; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EXPERIMENTATION; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PAW EDEMA; PHARMACOLOGICAL BLOCKING; PREDICTION; PROTECTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

EID: 15244345865     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.11.008     Document Type: Article

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