Chemical engineering of the peptidyl transferase center reveals an important role of the 2′-hydroxyl group of A2451

Nucleic Acids Research

Volumn 33, Issue 5, 2005, Pages 1618-1627

  Erlacher, Matthias D ^a   Lang, Kathrin ^b   Shankaran, Nisha ^c   Wotzel, Brigitte ^a   Hüttenhofer, Alexander ^a   Micura, Ronald ^b   Mankin, Alexander S ^c   Polacek, Norbert ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DEOXYRIBOSE; ADENINE; PEPTIDYLTRANSFERASE; RNA 23S; ADENOSINE; DRUG DERIVATIVE; NUCLEOSIDE;

ARTICLE; CHEMICAL ENGINEERING; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME RECONSTITUTION; ENZYME STRUCTURE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RIBOSOME; THERMUS AQUATICUS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE;

ADENINE; ADENOSINE; BASE SEQUENCE; CHEMICAL ENGINEERING; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEOSIDES; PEPTIDYL TRANSFERASES; RIBOSOMES; RNA, RIBOSOMAL, 23S;

EID: 15044352268     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gki308     Document Type: Article

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