An Extensive Interaction Interface between Thrombin and Factor V is Required for Factor V Activation

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 25143-25149

  Myles, Timothy ^a   Yun, Thomas H ^b   Hall, Scott W ^b   Leung, Lawrence L K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CHEMICAL ACTIVATION; COAGULATION; ELECTRIC FIELD EFFECTS; ELECTROPHORESIS; GELS; MUTAGENESIS; NEGATIVE IONS;

CLEAVAGE REACTIONS; HUMAN THROMBIN;

BIOCHEMISTRY;

ALANINE DERIVATIVE; ARGININE; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5A; LEUCINE; MUTANT PROTEIN; PROCOAGULANT; SODIUM ION; THROMBIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTRICITY; HUMAN; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; WILD TYPE; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMICAL STRUCTURE; DOSE RESPONSE; GENETICS; METABOLISM;

ANIMALIA; INSERTION SEQUENCES;

AMINO ACID SUBSTITUTION; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FACTOR V; HUMANS; MODELS, MOLECULAR; THROMBIN;

EID: 0035816595     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011324200     Document Type: Article

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