Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 7317-7325

  Plotkin, Lilian I ^a   Aguirre, J Ignacio ^a   Kousteni, Stavroula ^a   Manolagas, Stavros C ^a   Bellido, Teresita ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOCHEMISTRY; CELL CULTURE; ENZYMES; MOLECULAR BIOLOGY;

APOPTOSIS; BISPHOSPHATES; ESTROGEN; EXTRACELLULAR SIGNAL-REGULATED KINASE (ESRKS); OSTEOCYTES;

HORMONES;

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CASPASE; CCAAT ENHANCER BINDING PROTEIN BETA; CONNEXIN 43; ESTROGEN; ESTROGEN RECEPTOR; EXPORTIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAD; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

ANIMALS; APOPTOSIS; BONE AND BONES; CELL LINE; CONNEXIN 43; DIPHOSPHONATES; DRUG SYNERGISM; ESTROGENS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MICE; OSTEOCYTES; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 14844283132     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412817200     Document Type: Article

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