Regulation of Ras-MAPK pathway mitogenic activity by restricting nuclear entry of activated MAPK in endoderm differentiation of embryonic carcinoma and stem cells

Journal of Cell Biology

Volumn 164, Issue 5, 2004, Pages 689-699

  Smith, Elizabeth R ^a   Smedberg, Jennifer L ^a   Rula, Malgorzata E ^a   Xu, Xiang Xi ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

c Fos; Cytoskeleton; Elk 1; Nucleocytoplasmic translocation; Retinoic acid

Indexed keywords

COLCHICINE; CYTOCHALASIN D; MITOGEN ACTIVATED PROTEIN KINASE; NOCODAZOLE; PROTEIN C FOS; RAS PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR ELK 1;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; EMBRYONAL CARCINOMA; ENDODERM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; IMMUNOFLUORESCENCE MICROSCOPY; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, EMBRYONAL; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; COLCHICINE; CYTOCHALASIN D; CYTOSKELETON; ENDODERM; ENZYME ACTIVATION; FATTY ACIDS, UNSATURATED; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NOCODAZOLE; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-FOS; RAS PROTEINS; STEM CELLS; SUBCELLULAR FRACTIONS; TRETINOIN;

ANIMALIA; CERVUS ELAPHUS;

EID: 1442309964     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200312028     Document Type: Article

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