Hippocampal sclerosis contributes to dementia in the elderly

Neurology

Volumn 48, Issue 1, 1997, Pages 154-160

  Corey Bloom, J ^a,d   Sabbagh, M N ^a,d   Bondi, M W ^b,d   Hansen, L ^a,c   Alford, M F ^a   Masliah, E ^a,c   Thal, L J ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; CLINICAL ARTICLE; COGNITION; DEMENTIA; FEMALE; HIPPOCAMPUS; HUMAN; MALE; MULTIINFARCT DEMENTIA; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; SCLEROSIS; SENILE PLAQUE; SYNAPTIC TRANSMISSION;

EID: 0031016806     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.48.1.154     Document Type: Article

References (23)

1. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968; 114:797-811.
2. DeKosky S, Scheff S. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 1990;27:457-464.
3. Terry R, Masliah E, Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 1991;30: 572-580.
4. Hansen L, Salmon D, Galasko D, et al. The Lewy body variant of Alzheimer's disease: a clinical and pathological entity. Neurology 1990;40:1-8.
5. Perry R, Irving D, Blessed G, Fairbairn A, Perry E. Senile dementia of Lewy body type. J Neurol Sci 1990;95:119-139.
6. Carlson L, Gottfies C, Winblad B. Vascular dementia: etiological, pathogenetic, clinical and treatment aspects. Dementia 1994;5:129-214.
7. Dickson D, Crystal H, Matinee L, et al. Identification of normal and pathological aging in prospectively studied nondemented elderly humans. Neurobiol Aging 1991;13:179-189.
8. Crystal HA, Dickson DW, Sliwinski MJ, Lipton RB, Grober E, Marks-Nelson H, Antis P. Pathological markers associated with normal aging and dementia in the elderly. Ann Neurol 1993;34:566-573.
9. Dickson D, Davies P, Bevona C, et al. Hippocampal sclerosis: a common pathological feature of dementia in very old (≥80 years of age) humans. Acta Neuropathol 1994;88:212-221.
10. Jellinger K. Hippocampal sclerosis: a common pathological feature of dementia in very old humans. Acta Neuropathol 1994;88:599.
11. Volpe B, Petito C. Dementia with bilateral medial temporal lobe ischemia. Neurology 1985;35:1793-1797.
12. Clark A, White CI, Manze H, et al. Primary degenerative dementia without Alzheimer pathology. Can J Neurol Sci 1986;13:462-470.
13. Gearing M, Mirra S, Hedreen J, Sumi S, Hansen L, Heyman A. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease. Neurology 1995;45: 461-466.
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
15. Salmon D, Butters N. Neuropsychological assessment of dementia in the elderly. In: Katzman R, Rowe J, eds. Principles of geriatric neurology. Philadelphia: FA Davis, 1992.
16. Terry R, Peck A, DeTeresa R, Schlechter R, Horoupian DS. Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 1981;10:184-192.
17. Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259.
18. Alford MF, Masliah E, Hansen L, Terry R. A simple dot-immunobinding assay for quantification of synaptophysin-like immunoreactivity in human brain. J Histochem Cytochem 1994;42:283-287.
19. Salmon DP, Thal LJ, Butters N, Heindel WC. Longitudinal evaluation of dementia of the Alzheimer type: A comparison of 3 standardized mental status examinations. Neurology 1990; 40:1225-1230.
20. Aronson MK, Ooi WL, Morgenstern H, et al. Women, myocardial infarction, and dementia in the very old. Neurology 1990; 40:1102-1106.
21. Corey-Bloom J, Galasko D, Thal L, Jackson E. Clinical features distinguishing large cohorts with possible AD, probable AD and mixed dementia. J Am Geriatr Soc 1993;41:31-37.
22. Laplane D, Levasseur M, Pillon B, et al. Obsessive-compulsive and other behavioral changes with bilateral basal ganglia lesions. Brain 1989;112:699-725.
23. Tresch D, Folstein M, Robins P, Hazzard W. Prevalence and significance of cardiovascular disease and hypertension in elderly patients with dementia and depression. J Am Geriatr Soc 1985;33:530-537.