The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings

Metabolism: Clinical and Experimental

Volumn 54, Issue 3, 2005, Pages 361-369

  Jenner, Jennifer L ^a   Seman, Leo J ^a   Millar, John S ^b   Lamon Fava, Stefania ^a   Welty, Francine K ^a   Dolnikowski, Gregory G ^a   Marcovina, Santica M ^c   Lichtenstein, Alice H ^a   Barrett, P Hugh R ^d,e   DeLuca, Carl ^a   Schaefer, Ernst J ^a  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B100; LEUCINE; LIPOPROTEIN A;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEEDING; FEMALE; GAS CHROMATOGRAPHY; GEL ELECTROPHORESIS; HUMAN; LECTIN BINDING; MALE; MASS SPECTROMETRY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN ISOLATION; PROTEIN METABOLISM; PROTEIN SECRETION;

EID: 13844253559     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2004.10.001     Document Type: Article

References (49)

1. A. Rosengren, L. Wilhelmsen, E. Eriksson, B. Risberg, and H. Wedel Lipoprotein (a) and coronary heart disease: a prospective case-control study in a general population sample of middle aged men BMJ 301 1990 1248 1251
2. A.G. Bostom, D.R. Gagnon, L.A. Cupples, P.W.F. Wilson, J.L. Jenner, and J.M. Ordovas A prospective investigation of elevated lipoprotein (a) detected by electrophoresis and cardiovascular disease in women. The Framingham Heart Study Circulation 90 1994 1688 1695
3. A.A. Ariyo for the cardiovascular Health Study Lp(a) lipoprotein, vascular disease, and mortality in the elderly N. Engl. J. Med. 349 2003 2108 2115
4. J. Danesh, R. Collins, and R. Peto Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies Circulation 102 2000 1082 1085
5. S.M. Marcovina, H.H. Hobbs, and J.J. Albers Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature Clin. Chem. 42 1996 436 439
6. O. Klezovitch, and A.M. Scanu Heterogeneity of lipoprotein (a): growing complexities Curr. Opin. Lipidol. 6 1995 223 228
7. L.J. Seman, and W.C. Breckenridge Isolation and partial characterization of apolipoprotein (a) from human lipoprotein (a) Biochem. Cell. Biol. 64 1986 999 1009
8. J.L. Jenner, J.M. Ordovas, S. Lamon-Fava, M.M. Schaefer, P.W. Wilson, and W.P. Castelli Effects of age, sex, and menopausal status on plasma lipoprotein(a) levels. The Framingham Offspring Study Circulation 87 1993 1135 1141
9. A. Gaw, E. Boerwinkle, J.C. Cohen, and H.H. Hobbs Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus J. Clin. Invest. 93 1994 2526 2534
10. H.B.J. Brewer Effectiveness of diet and drugs in the treatment of patients with elevated Lp(a) levels. A. Scanu Lipoprotein(a) 1990 Academic Press, Inc. San Diego (Calif) 211 220
11. A. Gurakar, J.M. Hoeg, G. Kostner, N.M. Papadopoulos, and H.B. Brewer Jr. Levels of lipoprotein Lp(a) decline with neomycin and niacin treatment Atherosclerosis 57 1985 293 301
12. D. Crook, M. Sidhu, M. Seed, M. O'Donnell, and J.C. Stevenson Lipoprotein Lp(a) levels are reduced by danazol, an anabolic steroid Atherosclerosis 92 1992 41 47
13. M.R. Soma, M. Meschia, F. Bruschi, J.D. Morrisett, R. Paoletti, and R. Fumagalli Hormonal agents used in lowering lipoprotein(a) Chem. Phys. Lipids 67/68 1994 345 350
14. F. Krempler, G. Kostner, K. Bolzano, and F. Sandhofer Lipoprotein (a) is not a metabolic product of other lipoproteins containing apolipoprotein B Biochim. Biophys. Acta 575 1979 63 70
15. F. Krempler, G.M. Kostner, K. Bolzano, and F. Sandhofer Turnover of lipoprotein (a) in man J. Clin. Invest. 65 1980 1483 1490
16. J.D. Morrisett, J.W. Gaubatz, M.L. Nava, J.R. Guyton, A.L. Hoffman, and A.R. Opekun Metabolism of apo(a) and apoB-100 in human lipoprotein(a) A.L. Catapano A.M. Gotto Jr. R. Paoletti Drugs affecting lipid metabolism 1993 Kluwer Academic Publishers Dordrecht (The Netherlands) 161 167
17. D.J. Rader, W.A. Mann, W. Cain, H.G. Kraft, D. Usher, and L.A. Zech The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans J. Clin. Invest. 95 1995 1403 1408
18. D.J. Rader, W. Cain, K. Ikewaki, G. Talley, L.A. Zech, and D. Usher The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate J. Clin. Invest. 93 1994 2758 2763
19. D.J. Rader, W. Cain, L.A. Zech, D. Usher, and H.B. Brewer Jr. Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production J. Clin. Invest. 91 1993 443 447
20. W. Su, H. Campos, H. Judge, B.W. Walsh, and F.M. Sacks Metabolism of apo(a) and apoB100 of lipoprotein(a) in women: effect of postmenopausal estrogen replacement J. Clin. Endocrinol. Metab. 83 1998 3267 3276
21. T. Demant, K. Seeberg, A. Bedynek, and D. Seidel The metabolism of lipoprotein(a) and other apolipoprotein B-containing lipoproteins: a kinetic study in humans Atherosclerosis 157 2000 325 339
22. E.J. Schaefer, A.H. Lichtenstein, S. Lamon-Fava, J.H. Contois, Z. Li, and B.R. Goldin Effects of National Cholesterol Education Program Step 2 diets relatively high or relatively low in fish-derived fatty acids on plasma lipoproteins in middle-aged and elderly subjects Am. J. Clin. Nutr. 63 1996 234 241
23. J.S. Cohn, D.A. Wagner, S.D. Cohn, J.S. Millar, and E.J. Schaefer Measurement of very low density and low density lipoprotein apolipoprotein (apo) B-100 and high density lipoprotein apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding J. Clin. Invest. 85 1990 804 811
24. R.J. Havel, H.A. Eder, and J.H. Bragdon The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum J. Clin. Invest. 34 1955 1345 1363
25. J.R. McNamara, and E.J. Schaefer Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions Clin. Chim. Acta 166 1987 1 8
26. 2+ precipitation procedure for quantitation of high-density lipoprotein cholesterol Clin. Chem. 28 1982 1379 1388
27. E.J. Schaefer, S. Lamon-Fava, J.M. Ordovas, S.D. Cohn, M.M. Schaefer, and W.P. Castelli Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study J. Lipid Res. 35 1994 871 882
28. E.J. Schaefer, S. Lamon-Fava, S.D. Cohn, M.M. Schaefer, J.M. Ordovas, and W.P. Castelli Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study J. Lipid Res. 35 1994 779 792
29. S.M. Marcovina, J.J. Albers, E. Wijsman, Z. Zhang, N.H. Chapman, and H. Kennedy Differences in Lp(a) concentrations and apo(a) polymorphism between black and white Americans J. Lipid Res. 37 1996 2569 2585
30. L.J. Seman, J.L. Jenner, J.R. McNamara, and E.J. Schaefer Quantification of lipoprotein(a) in plasma by assaying cholesterol in lectin-bound plasma fraction Clin. Chem. 40 1994 400 403
31. C. Cobelli, G. Toffolo, D.M. Bier, and R. Nosadini Models to interpret kinetic data in stable isotope tracer studies Am. J. Physiol. 253 1987 E551 E564
32. K.G. Parhofer, P.H.R. Barrett, D.M. Bier, and G. Schonfeld Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes J. Lipid Res. 32 1991 1311 1323
33. F.K. Welty, A.H. Lichtenstein, H.R. Barrett, G.G. Dolnikowski, and E.J. Schaefer Human apolipoprotein (apo) B-48 and apoB-100 kinetics with stable isotopes Arterioscler. Thromb. Vasc. Biol. 19 1999 2966 2974
34. A.G. Bostom, L.A. Cupples, J.L. Jenner, J.M. Ordovas, L.J. Seman, and P.W.F. Wilson Elevated plasma lipoprotein(a) and coronary heart disease in men aged 55 years and younger JAMA 276 1996 544 548
35. J.W. Gaubatz, R.C. Hoogeveen, A.S. Hoffman, K.G. Ghazzaly, H.J. Pownall, and J. Guevara Jr. Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins J. Lipid Res. 42 2001 2058 2068
36. A.L. White, D.L. Rainwater, and R.E. Lanford Intracellular maturation of apolipoprotein(a) and assembly of lipoprotein(a) in primary baboon hepatocytes J. Lipid Res. 34 1993 509 517
37. V.N. Trieu, and W.J. McConathy A two-step model for lipoprotein(a) formation J. Biol. Chem. 270 1995 15471 15474
38. A.L. White, and R.E. Lanford Cell surface assembly of lipoprotein(a) in primary cultures of baboon hepatocytes J. Biol. Chem. 269 1994 28716 28723
39. S.L. Hofmann, D.L. Eaton, M.S. Brown, W.J. McConathy, J.L. Goldstein, and R.E. Hammer Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice J. Clin. Invest. 85 1990 1542 1547
40. B.L. Knight, Y.F.N. Perembelon, A.K. Soutar, D.P. Wade, and M. Seed Catabolism of lipoprotein(a) in familial hypercholesterolemic subjects Atherosclerosis 87 1991 227 237
41. K.M. Argraves, K.F. Kozarsky, J.T. Fallon, P.C. Harpel, and D.K. Strickland The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor J. Clin. Invest. 100 1997 2170 2181
42. M.L. Snyder, R.V. Hay, P.F. Whitington, A.M. Scanu, and G.M. Fless Binding and degradation of lipoprotein(a) and LDL by primary cultures of human hepatocytes. Comparison with cultured human monocyte-macrophages and fibroblasts Arterioscler. Thromb. 14 1994 770 779
43. S.P. Tam, X. Zhang, and M.L. Koschinsky Interaction of a recombinant form of apolipoprotein(a) with human fibroblasts and with the human hepatoma cell line HepG2 J. Lipid Res. 37 1996 518 533
44. V. Mooser, S.M. Marcovina, A.L. White, and H.H. Hobbs Kringle-containing fragments of apolipoprotein(a) circulate in human plasma and are excreted into the urine J. Clin. Invest. 98 1996 2414 2424
45. K.M. Kostner, G. Maurer, K. Huber, T. Stefenelli, H. Dieplinger, and E. Steyrer Urinary excretion of apo(a) fragments. Role in apo(a) catabolism Arterioscler. Thromb. Vasc. Biol. 16 1996 905 911
46. F. Kronenberg, G. Utermann, and H. Dieplinger Lipoprotein(a) in renal disease Am. J. Kidney Dis. 27 1996 1 25
47. E. Trenkwalder, A. Gruber, P. Konig, H. Dieplinger, and F. Kronenberg Increased plasma concentrations of LDL-unbound apo(a) in patients with end-stage renal disease Kidney Int. 52 1997 1685 1692
48. Y.F. Perombelon, J.J. Gallagher, N.B. Myant, A.K. Soutar, and B.L. Knight Lipoprotein(a) in subjects with familial defective apolipoprotein B-100 Atherosclerosis 92 1992 203 212
49. B.R. Gabel, L.F. May, S.M. Marcovina, and M.L. Koschinsky Lipoprotein(a) assembly. Quantitative assessment of the role of apo(a) kringle IV types 2-10 in particle formation Arterioscler. Thromb. Vasc. Biol. 16 1996 1559 1567