Corticosterone impairs MHC class I antigen presentation by dendritic cells via reduction of peptide generation

Journal of Neuroimmunology

Volumn 160, Issue 1-2, 2005, Pages 48-60

  Truckenmiller, Mary E ^a   Princiotta, Michael F ^b   Norbury, Christopher C ^a   Bonneau, Robert H ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Antigen processing presentation; Dendritic cells; Glucocorticoid; Virus

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE DERIVATIVE; REAGENT; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ANTIGENICITY; ARTICLE; CELL LEVEL; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFICACY; HOST RESISTANCE; HYBRIDOMA; IMMUNE SYSTEM; MENTAL STRESS; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; T LYMPHOCYTE; TECHNIQUE; VIRUS EXPRESSION; VIRUS INFECTION;

EID: 13844253234     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.10.024     Document Type: Article

References (58)

1. R.S. Allan, C.M. Smith, G.T. Belz, A.L. van Lint, L.M. Wakim, W.R. Heath, and F.R. Carbone Epidermal viral immunity induced by CD8 alpha+ dendritic cells but not by Langerhans cells Science 301 2003 1925 1928
2. C.S. Anglen, M.E. Truckenmiller, T.D. Schell, and R.H. Bonneau The dual role of CD8+ T lymphocytes in the development of stress-induced herpes simplex encephalitis J. Neuroimmunol. 140 2003 13 27
3. L.C. Anton, U. Schubert, I. Bacik, M.F. Princiotta, P.A. Wearsch, J. Gibbs, P.M. Day, C. Realini, M.C. Rechsteiner, J.R. Bennink, and J.W. Yewdell Intracellular localization of proteasomal degradation of a viral antigen J. Cell Biol. 146 1999 113 124
4. A.N. Antoniou, S.J. Powis, and T. Elliott Assembly and export of MHC class I peptide ligands Curr. Opin. Immunol. 15 2003 75 81
5. M. Bailey, H. Engler, J. Hunzeker, and J.F. Sheridan The hypothalamic-pituitary-adrenal axis and viral infection Viral Immunol. 16 2003 141 157
6. J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245
7. J. Banchereau, F. Briere, C. Caux, J. Davoust, S. Lebecque, Y.J. Liu, B. Pulendran, and K. Palucka Immunobiology of dendritic cells Annu. Rev. Immunol. 18 2000 767 811
8. T.W. Behrens, J. Jagadeesh, P. Scherle, G. Kearns, J. Yewdell, and L.M. Staudt Jaw1, A lymphoid-restricted membrane protein localized to the endoplasmic reticulum J. Immunol. 153 1994 682 690
9. T.W. Behrens, G.M. Kearns, J.J. Rivard, H.D. Bernstein, J.W. Yewdell, and L.M. Staudt Carboxyl-terminal targeting and novel post-translational processing of JAW1, a lymphoid protein of the endoplasmic reticulum J. Biol. Chem. 271 1996 23528 23534
10. J. Beninga, K.L. Rock, and A.L. Goldberg Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase J. Biol. Chem. 273 1998 18734 18742
11. R.H. Bonneau, D.A. Padgett, and J.F. Sheridan Psychoneuroimmune interactions in infectious disease: studies in animals R. Ader D.L. Felten N. Cohen Psychoneuroimmunology 3rd ed. 2001 Academic Press San Diego, CA 483 497
12. T. Deak, K.T. Nguyen, C.S. Cotter, M. Fleshner, L.R. Watkins, S.F. Maier, and R.L. Spencer Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor Brain Res. 847 1999 211 220
13. M.A. Derby, J. Wang, D.H. Margulies, and J.A. Berzofsky Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining Int. Immunol. 13 2001 817 824
14. J. Driscoll, M.G. Brown, D. Finley, and J.J. Monaco MHC-linked LMP gene products specifically alter peptidase activities of the proteasome Nature 365 1993 262 264
15. L.D. Falo Jr., K. Sullivan, B. Benacerraf, M.F. Mescher, and K.L. Rock Analysis of antigen presentation by metabolically inactive accessory cells and their isolated membranes Proc Natl. Acad. Sci. U. S. A. 82 1985 6647 6651
16. M. Fleshner, T. Deak, R.L. Spencer, M.L. Laudenslager, L.R. Watkins, and S.F. Maier A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure Endocrinology 136 1995 5336 5342
17. R. Hartmann-Petersen, M. Seeger, and C. Gordon Transferring substrates to the 26S proteasome Trends Biochem. Sci. 28 2003 26 31
18. K.B. Hendil, and R. Hartmann-Petersen Proteasomes: a complex story Curr. Protein Pept. Sci. 5 2004 131 151
19. C. Herberts, E. Reits, and J. Neefjes Proteases, proteases and proteases for presentation Nat. Immunol. 4 2003 306 308
20. G. Hermann, C.A. Tovar, F.M. Beck, and J.F. Sheridan Kinetics of glucocorticoid response to restraint stress and/or experimental influenza viral infection in two inbred strains of mice J. Neuroimmunol. 49 1994 25 33
21. J. Imai, M. Maruya, H. Yashiroda, I. Yahara, and K. Tanaka The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome EMBO J. 22 2003 3557 3567
22. S.M. Kaech, E.J. Wherry, and R. Ahmed Effector and memory T-cell differentiation: implications for vaccine development Nat. Rev., Immunol. 2 2002 251 262
23. G.J. Kant, J.R. Leu, S.M. Anderson, and E.H. Mougey Effects of chronic stress on plasma corticosterone Physiol. Behav. 40 1987 775 779
24. P.M. Kloetzel Antigen processing by the proteasome Nat. Rev., Mol. Cell Biol. 2 2001 179 187
25. P.M. Kloetzel, and F. Ossendorp Proteasome and peptidase function in MHC-class I-mediated antigen presentation Curr. Opin. Immunol. 16 2004 76 81
26. J. Kunisawa, and N. Shastri The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway Mol. Cell 12 2003 565 576
27. N.A. Leo, and R.H. Bonneau Chemical sympathectomy alters cytotoxic T lymphocyte responses to herpes symplex virus infection Ann. N.Y. Acad. Sci. 917 2000 923 934
28. B.S. McEwen, C.A. Biron, K.W. Brunson, K. Bulloch, W.H. Chambers, F.S. Dhabhar, R.H. Goldfarb, R.P. Kitson, A.H. Miller, R.L. Spencer, and J.M. Weiss The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions Brain Res. Rev. 23 1997 79 133
29. C.C. Norbury, M.F. Princiotta, J.R. Bennink, P. Wood, R.R. Brutkiewicz, T.J. Elliott, and J.R. Yewdell Multiple antigen-specific processing pathways for activating naive CD8+ T cells in vivo J. Immunol. 166 2001 4355 4362
30. C.C. Norbury, D. Malide, J.S. Gibbs, J.R. Bennink, and J.W. Yewdell Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo Nat. Immunol. 3 2002 265 271
31. E. Pamer, and P. Cresswell Mechanisms of MHC class I-restricted antigen processing Annu. Rev. Immunol. 16 1998 323 358
32. L. Piemonti, P. Monti, P. Allavena, M. Sironi, L. Soldini, B.E. Leone, C. Socci, and V. Di Carlo Glucocorticoids affect human dendritic cell differentiation and maturation J. Immunol. 162 1999 6473 6481
33. A. Porgador, J.W. Yewdell, Y. Deng, J.R. Bennink, and R.N. Germain Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody Immunity 6 1997 715 726
34. J. Pretell, R.S. Greenfield, and S.S. Tevethia Biology of simian virus 40 (SV40) transplantation antigen (TrAg). V In vitro demonstration of SV40 TrAg in SV40 infected nonpermissive mouse cells by the lymphocyte mediated cytotoxicity assay Virology 97 1979 32 41
35. M.F. Princiotta, U. Schubert, W. Chen, J.R. Bennink, J. Myung, C.M. Crews, and J.W. Yewdell Cells adapted to the proteasome inhibitor 4-hydroxy-5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival Proc. Natl. Acad. Sci. U. S. A. 98 2001 513 518
36. M.F. Princiotta, D. Finzi, S.B. Qian, J. Gibbs, S. Schuchmann, F. Buttgereit, J.R. Bennink, and J.W. Yewdell Quantitating protein synthesis, degradation, and endogenous antigen processing Immunity 18 2003 343 354
37. M.A. Purbhoo, D.J. Irvine, J.B. Huppa, and M.M. Davis T cell killing does not require the formation of a stable mature immunological synapse Nat. Immunol. 5 2004 524 530
38. E.A. Reits, J.C. Vos, M. Gromme, and J. Neefjes The major substrates for TAP in vivo are derived from newly synthesized proteins Nature 404 2000 774 778
39. E. Reits, A. Griekspoor, J. Neijssen, T. Groothuis, K. Jalink, P. van Veelen, H. Janssen, J. Calafat, J.W. Drijfhout, and J. Neefjes Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I Immunity 18 2003 97 108
40. E. Reits, J. Neijssen, C. Herberts, W. Benckhuijsen, L. Janssen, J.W. Drijfhout, and J. Neefjes A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation Immunity 20 2004 495 506
41. N.P. Restifo, I. Bacik, K.R. Irvine, J.W. Yewdell, B.J. McCabe, R.W. Anderson, L.C. Eisenlohr, S.A. Rosenberg, and J.R. Bennink Antigen processing in vivo and the elicitation of primary CTL responses J. Immunol. 154 1995 4414 4422
42. K.L. Rock, C. Gramm, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A.L. Goldberg Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules Cell 78 1994 761 771
43. S. Sanderson, and N. Shastri LacZ inducible, antigen/MHC-specific T cell hybrids Int. Immunol. 6 1994 369 376
44. T. Saric, J. Beninga, C.I. Graef, T.N. Akopian, K.L. Rock, and A.L. Goldberg Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase J. Biol. Chem. 276 2001 36474 36481
45. T. Saric, S.C. Chang, A. Hattori, I.A. York, S. Markant, K.L. Rock, M. Tsujimoto, and A.L. Goldberg An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides Nat. Immunol. 3 2002 1169 1176
46. U. Schubert, L.C. Anton, J. Gibbs, C.C. Norbury, J.W. Yewdell, and J.R. Bennink Rapid degradation of a large fraction of newly synthesized proteins by proteasomes Nature 404 2000 770 774
47. T. Serwold, F. Gonzalez, J. Kim, R. Jacob, and N. Shastri ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum Nature 419 2002 480 483
48. Z. Shen, G. Reznikoff, G. Dranoff, and K.L. Rock Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules J. Immunol. 158 1997 2723 2730
49. L.J. Sigal, H. Reiser, and K.L. Rock The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo J. Immunol. 161 1998 2740 2745
50. C.M. Smith, G.T. Belz, N.S. Wilson, J.A. Villadangos, K. Shortman, F.R. Carbone, and W.R. Heath Cutting edge: conventional CD8alpha(+) dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-1 J. Immunol. 170 2003 4437 4440
51. H.L. Snyder, I. Bacik, J.R. Bennink, G. Kearns, T.W. Behrens, T. Bachi, M. Orlowski, and J.W. Yewdell Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing J. Exp. Med. 186 1997 1087 1098
52. G.C. Turner, and A. Varshavsky Detecting and measuring cotranslational protein degradation in vivo Science 289 2000 2117 2120
53. J.C. Unkeless Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors J. Exp. Med. 150 1979 580 596
54. M.J. van Stipdonk, E.E. Lemmens, and S.P. Schoenberger Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation Nat. Immunol. 2 2001 423 429
55. J.I. Webster, L. Tonelli, and E.M. Sternberg Neuroendocrine regulation of immunity Annu. Rev. Immunol. 20 2002 125 163
56. I.A. York, S.C. Chang, T. Saric, J.A. Keys, J.M. Favreau, A.L. Goldberg, and K.L. Rock The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues Nat. Immunol. 3 2002 1177 1184
57. J.L. Yorty, and R.H. Bonneau Transplacental transfer and subsequent neonate utilization of herpes simplex virus-specific immunity are resilient to acute maternal stress J. Virol. 77 2003 6613 6619
58. F. Zhang, K. Su, X. Yang, D.B. Bowe, A.J. Paterson, and J.E. Kudlow O-GlcNAc modification is an endogenous inhibitor of the proteasome Cell 115 2003 715 725