메뉴 건너뛰기




Volumn 23, Issue 2, 2005, Pages 186-199

Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats

Author keywords

Mouse STO progenitor cells; Nonimmunosuppressed rats; Xenotransplantation

Indexed keywords

ALBUMIN; CELL MARKER; CYCLOOXYGENASE 1 INHIBITOR; DIPEPTIDYL PEPTIDASE IV; GAMMA INTERFERON; GLUCOSE 6 PHOSPHATASE; MESSENGER RNA; MITOCHONDRIAL DNA;

EID: 13744255475     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2004-0129     Document Type: Article
Times cited : (5)

References (60)
  • 1
    • 78651158197 scopus 로고
    • A stochastic model of stem cell proliferation based on the growth of spleen colony-forming cells
    • Till JE, McCulloch EA, Siminovitch L. A stochastic model of stem cell proliferation based on the growth of spleen colony-forming cells. Proc Natl Acad Sci U S A 1963;51:29-36.
    • (1963) Proc Natl Acad Sci U S A , vol.51 , pp. 29-36
    • Till, J.E.1    McCulloch, E.A.2    Siminovitch, L.3
  • 2
    • 13744260180 scopus 로고    scopus 로고
    • Totowa, NJ: Humana Press
    • Sell S, ed. Stem Cells Handbook. Totowa, NJ: Humana Press, 2004:1-509.
    • (2004) Stem Cells Handbook , pp. 1-509
    • Sell, S.1
  • 3
    • 0037237505 scopus 로고    scopus 로고
    • Reprogramming immune responses: Enabling cellular therapies and regenerative medicine
    • Down JD, White-Scharf ME. Reprogramming immune responses: enabling cellular therapies and regenerative medicine. STEM CELLS 2003;21:21-32.
    • (2003) STEM CELLS , vol.21 , pp. 21-32
    • Down, J.D.1    White-Scharf, M.E.2
  • 5
    • 0035342326 scopus 로고    scopus 로고
    • In search of the elusive Holy Grail: The mechanisms and prospects for achieving clinical transplantation tolerance
    • Auchincloss H Jr. In search of the elusive Holy Grail: the mechanisms and prospects for achieving clinical transplantation tolerance. Am J Transplant 2001;1:6-12.
    • (2001) Am J Transplant , vol.1 , pp. 6-12
    • Auchincloss Jr., H.1
  • 6
  • 7
    • 0035136417 scopus 로고    scopus 로고
    • Immunity or tolerance: Opposite outcomes of microchimerism from skin grafts
    • Anderson CC, Matzinger P. Immunity or tolerance: opposite outcomes of microchimerism from skin grafts. Nature Med 2001;7:80-87.
    • (2001) Nature Med , vol.7 , pp. 80-87
    • Anderson, C.C.1    Matzinger, P.2
  • 8
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M. Mixed chimerism and transplant tolerance. Immunity 2001;14:417-424.
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 9
    • 5444235785 scopus 로고    scopus 로고
    • Embryonic stem cells and the challenge of transplantation tolerance
    • Fairchild PJ, Cartland S, Nolan KF et al. Embryonic stem cells and the challenge of transplantation tolerance. Trends Immunol 2004;25:465-470.
    • (2004) Trends Immunol , vol.25 , pp. 465-470
    • Fairchild, P.J.1    Cartland, S.2    Nolan, K.F.3
  • 10
    • 0036304472 scopus 로고    scopus 로고
    • Xenotransplant cardiac chimera: Immune tolerance of adult stem cells
    • Saito T, Kuang JQ, Bittira B et al. Xenotransplant cardiac chimera: immune tolerance of adult stem cells. Ann Thorac Surg 2002;74:19-24.
    • (2002) Ann Thorac Surg , vol.74 , pp. 19-24
    • Saito, T.1    Kuang, J.Q.2    Bittira, B.3
  • 11
    • 0037820641 scopus 로고    scopus 로고
    • Neural progenitor cells lack immunogenicity and resist destruction as allografts
    • Hori J, Ng TF, Shatos M et al. Neural progenitor cells lack immunogenicity and resist destruction as allografts. STEM CELLS 2003;21:405-416.
    • (2003) STEM CELLS , vol.21 , pp. 405-416
    • Hori, J.1    Ng, T.F.2    Shatos, M.3
  • 12
    • 0037162551 scopus 로고    scopus 로고
    • Characterization of the expression of MHC proteins in human embryonic stem cells
    • Drukker M, Katz G, Urbach A et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A 2002;99:9864-9869.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9864-9869
    • Drukker, M.1    Katz, G.2    Urbach, A.3
  • 13
    • 0034710901 scopus 로고    scopus 로고
    • Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen
    • Kubota H, Reid LM. Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen. Proc Natl Acad Sci U S A 2000;97:12132-12137.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12132-12137
    • Kubota, H.1    Reid, L.M.2
  • 14
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-49.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 15
    • 0015424586 scopus 로고
    • Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: Evidence that congenic mouse strains SIM and SIM.R differ at the Fv-1 locus
    • Ware LM, Axelrad AA. Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: evidence that congenic mouse strains SIM and SIM.R differ at the Fv-1 locus. Virology 1972;50:339-348.
    • (1972) Virology , vol.50 , pp. 339-348
    • Ware, L.M.1    Axelrad, A.A.2
  • 16
    • 0038787478 scopus 로고    scopus 로고
    • Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from γ-irradiated mouse STO cells
    • Zhang M, Sell S, Leffert HL. Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from γ-irradiated mouse STO cells. STEM CELLS 2003;21:449-458.
    • (2003) STEM CELLS , vol.21 , pp. 449-458
    • Zhang, M.1    Sell, S.2    Leffert, H.L.3
  • 17
    • 13744250820 scopus 로고    scopus 로고
    • Transplantation of hepatic stem cells and potential applications for cell therapy
    • Sell S, ed. Totowa, NJ: Humana Press
    • Gupta S, Cho J-J. Transplantation of hepatic stem cells and potential applications for cell therapy. In: Sell S, ed. Stem Cells Handbook. Totowa, NJ: Humana Press, 2004:409-416.
    • (2004) Stem Cells Handbook , pp. 409-416
    • Gupta, S.1    Cho, J.-J.2
  • 18
    • 0016489816 scopus 로고
    • Differentiation of clonal lines of teratocarcinoma cells: Formation of embryoid bodies in vitro
    • Martin GR, Evans MJ. Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc Natl Acad Sci U S A 1975;72:1441-1445.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 1441-1445
    • Martin, G.R.1    Evans, M.J.2
  • 19
    • 0036549829 scopus 로고    scopus 로고
    • Spontaneous differentiation of porcine and bovine embryonic stem cells (epiblast) into astrocytes or neurons
    • Talbot NC, Powell AM, Garrett WM. Spontaneous differentiation of porcine and bovine embryonic stem cells (epiblast) into astrocytes or neurons. In Vitro Cell Dev Biol 2002;38:191-197.
    • (2002) In Vitro Cell Dev Biol , vol.38 , pp. 191-197
    • Talbot, N.C.1    Powell, A.M.2    Garrett, W.M.3
  • 20
    • 0031017151 scopus 로고    scopus 로고
    • Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro
    • Rogler LE. Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro. Am J Pathol 1997;150:591-602.
    • (1997) Am J Pathol , vol.150 , pp. 591-602
    • Rogler, L.E.1
  • 21
    • 0028998732 scopus 로고
    • Integration of transplanted hepatocytes in host liver plates demonstrated with dipeptidyl peptidase IV deficient rats
    • Gupta S, Rajvanshi P, Lee CD. Integration of transplanted hepatocytes in host liver plates demonstrated with dipeptidyl peptidase IV deficient rats. Proc Natl Acad Sci U S A 1995;92:5860-5864.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5860-5864
    • Gupta, S.1    Rajvanshi, P.2    Lee, C.D.3
  • 22
    • 0029816231 scopus 로고    scopus 로고
    • Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents
    • Rajvanshi P, Kerr A, Bhargava KK et al. Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents. Gastroenterology 1996;111:1092-1102.
    • (1996) Gastroenterology , vol.111 , pp. 1092-1102
    • Rajvanshi, P.1    Kerr, A.2    Bhargava, K.K.3
  • 23
    • 0033826587 scopus 로고    scopus 로고
    • Transplanted reporter cells help in defining onset of hepatocyte proliferation during the life of F344 rats
    • Sokhi RP, Rajvanshi P, Gupta S. Transplanted reporter cells help in defining onset of hepatocyte proliferation during the life of F344 rats. Am J Physiol Gastroint Liver Physiol 2000;279:G631-G640.
    • (2000) Am J Physiol Gastroint Liver Physiol , vol.279
    • Sokhi, R.P.1    Rajvanshi, P.2    Gupta, S.3
  • 24
    • 0032945255 scopus 로고    scopus 로고
    • Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver
    • Ott M, Rajvanshi P, Sokhi R et al. Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver. J Pathol 1999;187:365-373.
    • (1999) J Pathol , vol.187 , pp. 365-373
    • Ott, M.1    Rajvanshi, P.2    Sokhi, R.3
  • 26
    • 0032766646 scopus 로고    scopus 로고
    • Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene
    • Pan L, Sato S, Frederick JP et al. Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol 1999;19:5969-5980.
    • (1999) Mol Cell Biol , vol.19 , pp. 5969-5980
    • Pan, L.1    Sato, S.2    Frederick, J.P.3
  • 27
    • 0036156682 scopus 로고    scopus 로고
    • Derivation, characterization and phenotypic variation of hepatic progenitor cell lines isolated from adult rats
    • Yin L, Sun M, Ilic Z et al. Derivation, characterization and phenotypic variation of hepatic progenitor cell lines isolated from adult rats. Hepatology 2002;35:315-324.
    • (2002) Hepatology , vol.35 , pp. 315-324
    • Yin, L.1    Sun, M.2    Ilic, Z.3
  • 28
    • 0026088951 scopus 로고
    • A Fischer rat substrain deficient in dipeptidyl peptidase IV activity makes normal steady-state RNA levels and an altered protein: Use as a liver-cell transplantation model
    • Thompson NL, Hixson DC, Callanan H et al. A Fischer rat substrain deficient in dipeptidyl peptidase IV activity makes normal steady-state RNA levels and an altered protein: use as a liver-cell transplantation model. Biochem J 1991;273:497-502.
    • (1991) Biochem J , vol.273 , pp. 497-502
    • Thompson, N.L.1    Hixson, D.C.2    Callanan, H.3
  • 29
    • 84968995601 scopus 로고
    • Biochemistry and biology of N-acetyl-2-aminofluorene in primary cultures of adult rat hepatocytes
    • Leffert HL, Koch KS, Sell S et al. Biochemistry and biology of N-acetyl-2-aminofluorene in primary cultures of adult rat hepatocytes. USEPA Environ Sci Res 1983;29:119-133.
    • (1983) USEPA Environ Sci Res , vol.29 , pp. 119-133
    • Leffert, H.L.1    Koch, K.S.2    Sell, S.3
  • 31
    • 0028148853 scopus 로고
    • In vitro immune responsiveness of rats lacking active dipeptidylpeptidase IV
    • Coburn MC, Hixson DC, Reichner JS. In vitro immune responsiveness of rats lacking active dipeptidylpeptidase IV. Cell Immunol 1994;158:269-280.
    • (1994) Cell Immunol , vol.158 , pp. 269-280
    • Coburn, M.C.1    Hixson, D.C.2    Reichner, J.S.3
  • 32
    • 0033517154 scopus 로고    scopus 로고
    • CD26/Dipeptidyl peptidase IV in context: The different roles of a multifunctional ectoenzyme in malignant transformation
    • Iwata S, Morimoto C. CD26/Dipeptidyl peptidase IV in context: the different roles of a multifunctional ectoenzyme in malignant transformation. J Exp Med 1999;190:301-305.
    • (1999) J Exp Med , vol.190 , pp. 301-305
    • Iwata, S.1    Morimoto, C.2
  • 33
    • 0036733587 scopus 로고    scopus 로고
    • CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry
    • Boonacker EP, Wierenga EA, Smits HH et al. CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry. J Histochem Cytochem 2002;50:1169-1177.
    • (2002) J Histochem Cytochem , vol.50 , pp. 1169-1177
    • Boonacker, E.P.1    Wierenga, E.A.2    Smits, H.H.3
  • 34
    • 0005984244 scopus 로고
    • "Actively acquired 7 tolerance" of foreign cells
    • Billingham RE, Brent L, Medawar PB. "Actively acquired 7 tolerance" of foreign cells. Nature 1953;172:603-606.
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 35
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty KW, MacKenzie TC, Shaaban AF et al. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nature Med 2000;6:1282-1286.
    • (2000) Nature Med , vol.6 , pp. 1282-1286
    • Liechty, K.W.1    MacKenzie, T.C.2    Shaaban, A.F.3
  • 36
    • 0014661390 scopus 로고
    • Induction of immunological tolerance by porcine liver allografts
    • Calne RY, Sells RA, Pena JR et al. Induction of immunological tolerance by porcine liver allografts. Nature 1969;223:472-476.
    • (1969) Nature , vol.223 , pp. 472-476
    • Calne, R.Y.1    Sells, R.A.2    Pena, J.R.3
  • 37
    • 0038298787 scopus 로고    scopus 로고
    • Tolerogenic immunosuppression for organ transplantation
    • Starzl TE, Murase N, Abu-Elmagd K et al. Tolerogenic immunosuppression for organ transplantation. Lancet 2003;361:1502-1510.
    • (2003) Lancet , vol.361 , pp. 1502-1510
    • Starzl, T.E.1    Murase, N.2    Abu-Elmagd, K.3
  • 38
    • 0037270978 scopus 로고    scopus 로고
    • Hepatic T cells and liver tolerance
    • Crispe IN. Hepatic T cells and liver tolerance. Nat Rev Immunol 2003;3:51-62.
    • (2003) Nat Rev Immunol , vol.3 , pp. 51-62
    • Crispe, I.N.1
  • 39
    • 0037311318 scopus 로고    scopus 로고
    • Treatment of cirrhosis and liver failure in rats by hepatocyte xenotransplantation
    • Nagata H, Ito M, Cai J et al. Treatment of cirrhosis and liver failure in rats by hepatocyte xenotransplantation. Gastroenterology 2003;124:422-431.
    • (2003) Gastroenterology , vol.124 , pp. 422-431
    • Nagata, H.1    Ito, M.2    Cai, J.3
  • 40
    • 0020977018 scopus 로고
    • Immunobiology of tissue transplantation: A return to the passenger leukocyte concept
    • Lafferty KJ, Prowse SJ, Simeonovic CJ. Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Annu Rev Immunol 1983;1:143-173.
    • (1983) Annu Rev Immunol , vol.1 , pp. 143-173
    • Lafferty, K.J.1    Prowse, S.J.2    Simeonovic, C.J.3
  • 41
    • 0022638110 scopus 로고
    • The regulation of expression of major histocompatibility products
    • Halloran PF, Wadgymar A, Autenreid P. The regulation of expression of major histocompatibility products. Transplantation 1986;41:413-420.
    • (1986) Transplantation , vol.41 , pp. 413-420
    • Halloran, P.F.1    Wadgymar, A.2    Autenreid, P.3
  • 42
    • 0022511656 scopus 로고
    • Expression of class I transplantation antigens
    • Harris HW, Gill TJ. Expression of class I transplantation antigens. Transplantation 1986;42:109-117.
    • (1986) Transplantation , vol.42 , pp. 109-117
    • Harris, H.W.1    Gill, T.J.2
  • 43
    • 0031022048 scopus 로고    scopus 로고
    • Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation
    • Gunsalus JR, Brady DA, Coulter SM et al. Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation. Nature Med 1997;3:48-53.
    • (1997) Nature Med , vol.3 , pp. 48-53
    • Gunsalus, J.R.1    Brady, D.A.2    Coulter, S.M.3
  • 44
    • 0034681522 scopus 로고    scopus 로고
    • Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes
    • Kobayashi N, Fujiwara T, Westerman KA et al. Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes. Science 2000;287:1258-1262.
    • (2000) Science , vol.287 , pp. 1258-1262
    • Kobayashi, N.1    Fujiwara, T.2    Westerman, K.A.3
  • 45
    • 0036794454 scopus 로고    scopus 로고
    • Detection of albumin synthesis in transplanted porcine hepatocytes in mice
    • Nishitai R, Plummer TB, Platt JL. Detection of albumin synthesis in transplanted porcine hepatocytes in mice. Liver Transplant 2002;18:972-974.
    • (2002) Liver Transplant , vol.18 , pp. 972-974
    • Nishitai, R.1    Plummer, T.B.2    Platt, J.L.3
  • 46
    • 0037183883 scopus 로고    scopus 로고
    • Generation of live young from xenografted mouse ovaries
    • Snow M, Cox SL, Jenkin G et al. Generation of live young from xenografted mouse ovaries. Science 2002;297:2227.
    • (2002) Science , vol.297 , pp. 2227
    • Snow, M.1    Cox, S.L.2    Jenkin, G.3
  • 47
    • 3543018487 scopus 로고    scopus 로고
    • Human embryonic stem cells possess immune-privileged properties
    • Li L, Baroja ML, Majumdar A et al. Human embryonic stem cells possess immune-privileged properties. STEM CELLS 2004;22:448-456.
    • (2004) STEM CELLS , vol.22 , pp. 448-456
    • Li, L.1    Baroja, M.L.2    Majumdar, A.3
  • 48
    • 1442306695 scopus 로고    scopus 로고
    • The importance of knowing your identity: Sources of confusion in stem cell biology
    • Grompe M. The importance of knowing your identity: sources of confusion in stem cell biology. Hepatology 2004;39:35-37.
    • (2004) Hepatology , vol.39 , pp. 35-37
    • Grompe, M.1
  • 49
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990;248:1349-1356.
    • (1990) Science , vol.248 , pp. 1349-1356
    • Schwartz, R.H.1
  • 50
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-1170.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 51
    • 0033958372 scopus 로고    scopus 로고
    • Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation
    • Theise ND, Badve S, Saxena R et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000;31:235-240.
    • (2000) Hepatology , vol.31 , pp. 235-240
    • Theise, N.D.1    Badve, S.2    Saxena, R.3
  • 52
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
    • Krause DS, Theise ND, Collector MI et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-377.
    • (2001) Cell , vol.105 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3
  • 53
    • 0033694301 scopus 로고    scopus 로고
    • Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    • Lagasse E, Conners H, Al-Shalimy M et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-1234.
    • (2000) Nat Med , vol.6 , pp. 1229-1234
    • Lagasse, E.1    Conners, H.2    Al-Shalimy, M.3
  • 54
    • 0037464574 scopus 로고    scopus 로고
    • Cell fusion is the principal source of bone-marrow-derived hepatocytes
    • Wang X, Willenbring H, Akkari Y et al. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 2003;422:897-901.
    • (2003) Nature , vol.422 , pp. 897-901
    • Wang, X.1    Willenbring, H.2    Akkari, Y.3
  • 55
    • 0037464545 scopus 로고    scopus 로고
    • Transplanted bone marrow regenerates liver by cell fusion
    • Vassilopoulos G, Wang P-R, Russell DW. Transplanted bone marrow regenerates liver by cell fusion. Nature 2003;422:901-904.
    • (2003) Nature , vol.422 , pp. 901-904
    • Vassilopoulos, G.1    Wang, P.-R.2    Russell, D.W.3
  • 56
    • 0038210247 scopus 로고    scopus 로고
    • Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of fusion
    • Newsome PN, Johannessen I, Boyle S et al. Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of fusion. Gastroenterology 2003;124:1891-1900.
    • (2003) Gastroenterology , vol.124 , pp. 1891-1900
    • Newsome, P.N.1    Johannessen, I.2    Boyle, S.3
  • 57
    • 0037791959 scopus 로고    scopus 로고
    • Transplanted human cord blood cells give rise to hepatocytes in engrafted mice
    • Ishikawa F, Drake CJ, Yang S et al. Transplanted human cord blood cells give rise to hepatocytes in engrafted mice. Ann N Y Acad Sci 2003;996:174-185.
    • (2003) Ann N Y Acad Sci , vol.996 , pp. 174-185
    • Ishikawa, F.1    Drake, C.J.2    Yang, S.3
  • 58
    • 0242584006 scopus 로고    scopus 로고
    • Fusion of bone marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes
    • Alvarez-Dolando NA, Pardal R, Garcia-Verdungo JM et al. Fusion of bone marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 2003;425:968-973.
    • (2003) Nature , vol.425 , pp. 968-973
    • Alvarez-Dolando, N.A.1    Pardal, R.2    Garcia-Verdungo, J.M.3
  • 59
    • 0037364517 scopus 로고    scopus 로고
    • In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow with no evidence of cell fusion
    • Ianus A, Holz GG, Theise ND et al. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow with no evidence of cell fusion. J Clin Invest 2003;111:843-850.
    • (2003) J Clin Invest , vol.111 , pp. 843-850
    • Ianus, A.1    Holz, G.G.2    Theise, N.D.3
  • 60
    • 0017704436 scopus 로고
    • Metastasis results from preexisting variant cells within a malignant tumor
    • Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977;197:893-895.
    • (1977) Science , vol.197 , pp. 893-895
    • Fidler, I.J.1    Kripke, M.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.