-
1
-
-
13444310407
-
-
Information from the WHO website: www.who.int/nut/obs.htm
-
-
-
-
2
-
-
13444302201
-
-
Information from the National Center for Health Statistics available in website: www.cdc.gov/nchs/products/pubs/pubd/hestats/ obese/obse99.htm
-
-
-
-
3
-
-
0037048695
-
Prevalence and trends in overweight among US children and adolescents, 1999-2000
-
Ogden CL, Flega KM, Carroll MD, Johnson CL Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA 2002;288(14):1728-1732
-
(2002)
JAMA
, vol.288
, Issue.14
, pp. 1728-1732
-
-
Ogden, C.L.1
Flega, K.M.2
Carroll, M.D.3
Johnson, C.L.4
-
4
-
-
0024160877
-
Banting lecture 1988. Role of insulin resistance in human disease
-
Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37(12):1595-1607
-
(1988)
Diabetes
, vol.37
, Issue.12
, pp. 1595-1607
-
-
Reaven, G.M.1
-
5
-
-
0024391834
-
The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridimia, and hypertension
-
Kaplan NM. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridimia, and hypertension. Arch Intern Med 1989;149(7):1514-1520
-
(1989)
Arch Intern Med
, vol.149
, Issue.7
, pp. 1514-1520
-
-
Kaplan, N.M.1
-
6
-
-
0025748673
-
Metabolic implications of body fat distribution
-
Bjorntorp P. Metabolic implications of body fat distribution. Diabetes Care. 1991;14(12):1132-1143
-
(1991)
Diabetes Care
, vol.14
, Issue.12
, pp. 1132-1143
-
-
Bjorntorp, P.1
-
7
-
-
73649168830
-
Forearm metabolism in obesity and its response to intraarterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism
-
Rabinowitz D, Zierler KL. Forearm metabolism in obesity and its response to intraarterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism. J C Invest 1962;12:2173-2181
-
(1962)
J C Invest
, vol.12
, pp. 2173-2181
-
-
Rabinowitz, D.1
Zierler, K.L.2
-
8
-
-
0033436355
-
Insulin and leptin: Dual adiposity signals to the brain for the regulation of food intake and body weight
-
Baskin DG, Ficlewicz Lattemann D, Seeley RJ, Woods SC, Porte D Jr, Schwartz MW. Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res 1999;848(1-2):114-123
-
(1999)
Brain Res
, vol.848
, Issue.1-2
, pp. 114-123
-
-
Baskin, D.G.1
Ficlewicz Lattemann, D.2
Seeley, R.J.3
Woods, S.C.4
Porte Jr., D.5
Schwartz, M.W.6
-
9
-
-
0041859272
-
To eat or not to eat - How the gut talks to the brain
-
Korner J, Leibel RL. To eat or not to eat - How the gut talks to the brain. N Engl J Med 2003;349:926-928
-
(2003)
N Engl J Med
, vol.349
, pp. 926-928
-
-
Korner, J.1
Leibel, R.L.2
-
10
-
-
0032065645
-
What's in a name? In search of leptin's physiologic role
-
Flier J F. What's in a name? In search of leptin's physiologic role. J C Invest 1998;83(5):1407-1413
-
(1998)
J C Invest
, vol.83
, Issue.5
, pp. 1407-1413
-
-
Flier, J.F.1
-
11
-
-
0037423143
-
Cellular warriors at the battle of the bulge
-
Marx J. Cellular warriors at the battle of the bulge. Science 2003;299:846-849
-
(2003)
Science
, vol.299
, pp. 846-849
-
-
Marx, J.1
-
12
-
-
0035041922
-
Obesity as a neuroedocrine disease: Lessons to be learned from proopiomelanocortin and melanocortin receptor mutations in mice and men
-
Wardlaw SL. Obesity as a neuroedocrine disease: lessons to be learned from proopiomelanocortin and melanocortin receptor mutations in mice and men. J Clin Endocrinol Metab 2001;86:1442-1446
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1442-1446
-
-
Wardlaw, S.L.1
-
13
-
-
0037370258
-
The emerging science of body weight regulation and 1st impact on obesity treatment
-
Korner J, Aronne LJ. The emerging science of body weight regulation and 1st impact on obesity treatment. J Clin Invest 2003;111:565-570
-
(2003)
J Clin Invest
, vol.111
, pp. 565-570
-
-
Korner, J.1
Aronne, L.J.2
-
14
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
16
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Muller-Wieland D, Kahn CR. Role of brain insulin receptor in control of body weight and reproduction. Science 2000;289:2122-2125
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Muller-Wieland, D.9
Kahn, C.R.10
-
17
-
-
73649168830
-
Forearm metabolism in obesity and its response to intraarterial insulin. Characterisation of insulin resistance and evidence for adaptive hyperisnulism
-
Rabinowitz D and Zierler KL. Forearm metabolism in obesity and its response to intraarterial insulin. Characterisation of insulin resistance and evidence for adaptive hyperisnulism. J Clin Invest 1962;12:2173-2181
-
(1962)
J Clin Invest
, vol.12
, pp. 2173-2181
-
-
Rabinowitz, D.1
Zierler, K.L.2
-
18
-
-
0035856920
-
Global and societal implications of diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J. Global and societal implications of diabetes epidemic. Nature 2003;414:782-787
-
(2003)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
19
-
-
0029037649
-
Pathophysiology of insulin resistance in human disease
-
Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995;75:473-486
-
(1995)
Physiol Rev
, vol.75
, pp. 473-486
-
-
Reaven, G.M.1
-
20
-
-
0030884698
-
Insulin resistance and hyper secretion in obesity
-
Ferrannini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G. Insulin resistance and hyper secretion in obesity. J Clin Invest 1997;100:1166-1173
-
(1997)
J Clin Invest
, vol.100
, pp. 1166-1173
-
-
Ferrannini, E.1
Natali, A.2
Bell, P.3
Cavallo-Perin, P.4
Lalic, N.5
Mingrone, G.6
-
21
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000;106:473-481
-
(2000)
J Clin Invest
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
22
-
-
0344305782
-
Insulin signalling in health and disease
-
White MF. Insulin signalling in health and disease. Science 2003;302:1710-1711
-
(2003)
Science
, vol.302
, pp. 1710-1711
-
-
White, M.F.1
-
23
-
-
0033595121
-
Glucose transporters and insulin action. Implication for insulin resistance and diabetes mellitus
-
Shepherd PR, Kahn BB. Glucose transporters and insulin action. Implication for insulin resistance and diabetes mellitus. N Engl J Med 1999;341:248-257
-
(1999)
N Engl J Med
, vol.341
, pp. 248-257
-
-
Shepherd, P.R.1
Kahn, B.B.2
-
24
-
-
0033525870
-
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene
-
Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Lay AL, Normandin D, Cheng A, Himms-Hasen J, Chan CC, Ramachandran C, Gresser MJ, Tremblay ML, Kennedy BP. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 1999;283:1544-1546
-
(1999)
Science
, vol.283
, pp. 1544-1546
-
-
Elchebly, M.1
Payette, P.2
Michaliszyn, E.3
Cromlish, W.4
Collins, S.5
Lay, A.L.6
Normandin, D.7
Cheng, A.8
Himms-Hasen, J.9
Chan, C.C.10
Ramachandran, C.11
Gresser, M.J.12
Tremblay, M.L.13
Kennedy, B.P.14
-
25
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A, Lauret D, Marcucci M, Griffin ME, Dufour S, Cline GW, Slezak LA, Andersen DK, Hundal RS, Rothman DL, Peterson KF, Shulman GA. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 1999;103(2):253-259
-
(1999)
J Clin Invest
, vol.103
, Issue.2
, pp. 253-259
-
-
Dresner, A.1
Lauret, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
Peterson, K.F.11
Shulman, G.A.12
-
26
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
December
-
Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, Atcheson B, White MF, Kraegen EW, Shulman GI. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. JBC 2002 December; 277(52):50230-50236
-
(2002)
JBC
, vol.277
, Issue.52
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
27
-
-
3042621978
-
The human obesity gene map: The 2003 update
-
Snyder EE, Walts B, Perusse L, Chagnon YC, Weisnagel SJ, Rankimen T, Bouchard C. The human obesity gene map: the 2003 update. Obes Res 2004;12(3):369-439
-
(2004)
Obes Res
, vol.12
, Issue.3
, pp. 369-439
-
-
Snyder, E.E.1
Walts, B.2
Perusse, L.3
Chagnon, Y.C.4
Weisnagel, S.J.5
Rankimen, T.6
Bouchard, C.7
-
28
-
-
70349566593
-
Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
-
Neel JV. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 1962;14:353-362
-
(1962)
Am J Hum Genet
, vol.14
, pp. 353-362
-
-
Neel, J.V.1
-
29
-
-
0026101206
-
Archaeology of NIDDM. Excavation of the "thrifty" genotype
-
Wendorf M, Goldfine ID. Archaeology of NIDDM. Excavation of the "thrifty" genotype. Diabetes 1991;40:161-165
-
(1991)
Diabetes
, vol.40
, pp. 161-165
-
-
Wendorf, M.1
Goldfine, I.D.2
-
30
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hypo responsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Faroogi SI, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, O'Rahilly S. Beneficial effects of leptin on obesity, T cell hypo responsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002;110:1093-1103
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Faroogi, S.I.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
Sanna, V.7
Jebb, S.A.8
Perna, F.9
Fontana, S.10
Lechler, R.I.11
DePaoli, A.M.12
O'Rahilly, S.13
|