메뉴 건너뛰기




Volumn 228, Issue 2, 2005, Pages 210-214

CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; PROTEOLIPID PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 13444261147     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2004.10.014     Document Type: Conference Paper
Times cited : (33)

References (67)
  • 2
    • 0021328623 scopus 로고
    • Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice
    • F. Mokhtarian, D.E. McFarlin, and C.S. Raine Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice Nature 309 1984 356 358
    • (1984) Nature , vol.309 , pp. 356-358
    • Mokhtarian, F.1    McFarlin, D.E.2    Raine, C.S.3
  • 3
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • S.S. Zamvil, and L. Steinman The T lymphocyte in experimental allergic encephalomyelitis Annu. Rev. Immunol. 8 1990 579 621
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 4
    • 0019978357 scopus 로고
    • Acute autoimmune encephalomyelitis in mice. II: Susceptibility is controlled by the combination of H-2 and histamine sensitization genes
    • D.S. Linthicum, and J.A. Frelinger Acute autoimmune encephalomyelitis in mice. II: Susceptibility is controlled by the combination of H-2 and histamine sensitization genes J. Exp. Med. 156 1982 31 40
    • (1982) J. Exp. Med. , vol.156 , pp. 31-40
    • Linthicum, D.S.1    Frelinger, J.A.2
  • 5
    • 13444307398 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis
    • P. Rao, and B.M. Segal Experimental autoimmune encephalomyelitis Methods Mol. Med. 102 2004 363 376
    • (2004) Methods Mol. Med. , vol.102 , pp. 363-376
    • Rao, P.1    Segal, B.M.2
  • 6
    • 0019465748 scopus 로고
    • Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: Requirement for Lyt 1+ 2- T lymphocytes
    • C.B. Pettinelli, and D.E. McFarlin Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes J. Immunol. 127 1981 1420 1423
    • (1981) J. Immunol. , vol.127 , pp. 1420-1423
    • Pettinelli, C.B.1    McFarlin, D.E.2
  • 7
    • 0025735650 scopus 로고
    • Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides
    • V.K. Kuchroo, R.A. Sobel, T. Yamamura, E. Greenfield, M.E. Dorf, and M.B. Lees Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides Pathobiology 59 1991 305 312
    • (1991) Pathobiology , vol.59 , pp. 305-312
    • Kuchroo, V.K.1    Sobel, R.A.2    Yamamura, T.3    Greenfield, E.4    Dorf, M.E.5    Lees, M.B.6
  • 8
    • 0021966856 scopus 로고
    • T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination
    • S. Zamvil, P. Nelson, J. Trotter, D. Mitchell, R. Knobler, and R. Fritz T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination Nature 317 1985 355 358
    • (1985) Nature , vol.317 , pp. 355-358
    • Zamvil, S.1    Nelson, P.2    Trotter, J.3    Mitchell, D.4    Knobler, R.5    Fritz, R.6
  • 9
    • 0021913219 scopus 로고
    • Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker
    • M.K. Waldor, S. Sriram, R. Hardy, L.A. Herzenberg, L.A. Herzenberg, and L. Lanier Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker Science 227 1985 415 417
    • (1985) Science , vol.227 , pp. 415-417
    • Waldor, M.K.1    Sriram, S.2    Hardy, R.3    Herzenberg, L.A.4    Herzenberg, L.A.5    Lanier, L.6
  • 10
    • 0021341456 scopus 로고
    • Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis
    • D. Cohen, O. Cohen, A. Marcadet, C. Massart, M. Lathrop, and I. Deschamps Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis Proc. Natl. Acad. Sci. U. S. A. 81 1984 1774 1778
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , pp. 1774-1778
    • Cohen, D.1    Cohen, O.2    Marcadet, A.3    Massart, C.4    Lathrop, M.5    Deschamps, I.6
  • 11
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
    • B. Bielekova, B. Goodwin, N. Richert, I. Cortese, T. Kondo, and G. Afshar Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand Nat. Med. 6 2000 1167 1175
    • (2000) Nat. Med. , vol.6 , pp. 1167-1175
    • Bielekova, B.1    Goodwin, B.2    Richert, N.3    Cortese, I.4    Kondo, T.5    Afshar, G.6
  • 12
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • T.R. Mosmann, and R.L. Coffman TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 13
    • 0029150012 scopus 로고
    • Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease
    • D.J. Cua, D.R. Hinton, and S.A. Stohlman Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease J. Immunol. 155 1995 4052 4059
    • (1995) J. Immunol. , vol.155 , pp. 4052-4059
    • Cua, D.J.1    Hinton, D.R.2    Stohlman, S.A.3
  • 14
    • 0028829010 scopus 로고
    • Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells
    • A. Khoruts, S.D. Miller, and M.K. Jenkins Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells J. Immunol. 155 1995 5011 5017
    • (1995) J. Immunol. , vol.155 , pp. 5011-5017
    • Khoruts, A.1    Miller, S.D.2    Jenkins, M.K.3
  • 15
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • M.B. Powell, D. Mitchell, J. Lederman, J. Buckmeier, S.S. Zamvil, and M. Graham Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity Int. Immunol. 2 1990 539 544
    • (1990) Int. Immunol. , vol.2 , pp. 539-544
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6
  • 16
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • D.G. Ando, J. Clayton, D. Kono, J.L. Urban, and E.E. Sercarz Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype Cell. Immunol. 124 1989 132 143
    • (1989) Cell. Immunol. , vol.124 , pp. 132-143
    • Ando, D.G.1    Clayton, J.2    Kono, D.3    Urban, J.L.4    Sercarz, E.E.5
  • 17
    • 0030248470 scopus 로고    scopus 로고
    • Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: Persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta
    • S. Issazadeh, J.C. Lorentzen, M.I. Mustafa, B. Hojeberg, A. Mussener, and T. Olsson Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta J. Neuroimmunol. 69 1996 103 115
    • (1996) J. Neuroimmunol. , vol.69 , pp. 103-115
    • Issazadeh, S.1    Lorentzen, J.C.2    Mustafa, M.I.3    Hojeberg, B.4    Mussener, A.5    Olsson, T.6
  • 18
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • M.K. Kennedy, D.S. Torrance, K.S. Picha, and K.M. Mohler Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery J. Immunol. 149 1992 2496 2505
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 19
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • A. Windhagen, J. Newcombe, F. Dangond, C. Strand, M.N. Woodroofe, and M.L. Cuzner Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions J. Exp. Med. 182 1995 1985 1996
    • (1995) J. Exp. Med. , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3    Strand, C.4    Woodroofe, M.N.5    Cuzner, M.L.6
  • 20
    • 0033998708 scopus 로고    scopus 로고
    • Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis
    • C.D. Rohowsky-Kochan, D. Molinaro, and S.D. Cook Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis Mult. Scler. 6 2000 69 77
    • (2000) Mult. Scler. , vol.6 , pp. 69-77
    • Rohowsky-Kochan, C.D.1    Molinaro, D.2    Cook, S.D.3
  • 21
    • 0027889130 scopus 로고
    • Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis
    • F.D. Lublin, R.L. Knobler, B. Kalman, M. Goldhaber, J. Marini, and M. Perrault Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis Autoimmunity 16 1993 267 274
    • (1993) Autoimmunity , vol.16 , pp. 267-274
    • Lublin, F.D.1    Knobler, R.L.2    Kalman, B.3    Goldhaber, M.4    Marini, J.5    Perrault, M.6
  • 22
    • 0029829385 scopus 로고    scopus 로고
    • Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: Enhancement by monoclonal antibodies against interferon-gamma
    • H. Heremans, C. Dillen, M. Groenen, E. Martens, and A. Billiau Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma Eur. J. Immunol. 26 1996 2393 2398
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2393-2398
    • Heremans, H.1    Dillen, C.2    Groenen, M.3    Martens, E.4    Billiau, A.5
  • 23
    • 0026558531 scopus 로고
    • Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse
    • T.T. Duong, J. St. Louis, J.J. Gilbert, F.D. Finkelman, and G.H. Strejan Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse J. Neuroimmunol. 36 1992 105 115
    • (1992) J. Neuroimmunol. , vol.36 , pp. 105-115
    • Duong, T.T.1    St. Louis, J.2    Gilbert, J.J.3    Finkelman, F.D.4    Strejan, G.H.5
  • 24
    • 0028170342 scopus 로고
    • Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains
    • T.T. Duong, F.D. Finkelman, B. Singh, and G.H. Strejan Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains J. Neuroimmunol. 53 1994 101 107
    • (1994) J. Neuroimmunol. , vol.53 , pp. 101-107
    • Duong, T.T.1    Finkelman, F.D.2    Singh, B.3    Strejan, G.H.4
  • 25
    • 0029671318 scopus 로고    scopus 로고
    • Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
    • I.A. Ferber, S. Brocke, C. Taylor-Edwards, W. Ridgway, C. Dinisco, and L. Steinman Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE) J. Immunol. 156 1996 5 7
    • (1996) J. Immunol. , vol.156 , pp. 5-7
    • Ferber, I.A.1    Brocke, S.2    Taylor-Edwards, C.3    Ridgway, W.4    Dinisco, C.5    Steinman, L.6
  • 26
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-gamma confers resistance to experimental allergic encephalomyelitis
    • M. Krakowski, and T. Owens Interferon-gamma confers resistance to experimental allergic encephalomyelitis Eur. J. Immunol. 26 1996 1641 1646
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 27
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • B.M. Segal, B.K. Dwyer, and E.M. Shevach An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease J. Exp. Med. 187 1998 537 546
    • (1998) J. Exp. Med. , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3
  • 28
    • 0030587910 scopus 로고    scopus 로고
    • IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • D.O. Willenborg, S. Fordham, C.C. Bernard, W.B. Cowden, and I.A. Ramshaw IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis J. Immunol. 157 1996 3223 3227
    • (1996) J. Immunol. , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 29
    • 2642698865 scopus 로고    scopus 로고
    • Challenging cytokine redundancy: Inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice
    • D. Sean Riminton, H. Korner, D.H. Strickland, F.A. Lemckert, J.D. Pollard, and J.D. Sedgwick Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice J. Exp. Med. 187 1998 1517 1528
    • (1998) J. Exp. Med. , vol.187 , pp. 1517-1528
    • Sean Riminton, D.1    Korner, H.2    Strickland, D.H.3    Lemckert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 30
    • 0031916192 scopus 로고    scopus 로고
    • TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
    • J. Liu, M.W. Marino, G. Wong, D. Grail, A. Dunn, and J. Bettadapura TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination Nat. Med. 4 1998 78 83
    • (1998) Nat. Med. , vol.4 , pp. 78-83
    • Liu, J.1    Marino, M.W.2    Wong, G.3    Grail, D.4    Dunn, A.5    Bettadapura, J.6
  • 31
    • 0030918326 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis
    • K. Frei, H.P. Eugster, M. Bopst, C.S. Constantinescu, E. Lavi, and A. Fontana Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis J. Exp. Med. 185 1997 2177 2182
    • (1997) J. Exp. Med. , vol.185 , pp. 2177-2182
    • Frei, K.1    Eugster, H.P.2    Bopst, M.3    Constantinescu, C.S.4    Lavi, E.5    Fontana, A.6
  • 32
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • G. Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat. Rev., Immunol. 3 2003 133 146
    • (2003) Nat. Rev., Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 33
    • 0036604306 scopus 로고    scopus 로고
    • A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
    • C. Parham, M. Chirica, J. Timans, E. Vaisberg, M. Travis, and J. Cheung A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R J. Immunol. 168 2002 5699 5708
    • (2002) J. Immunol. , vol.168 , pp. 5699-5708
    • Parham, C.1    Chirica, M.2    Timans, J.3    Vaisberg, E.4    Travis, M.5    Cheung, J.6
  • 34
    • 0036677420 scopus 로고    scopus 로고
    • Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
    • B. Becher, B.G. Durell, and R.J. Noelle Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12 J. Clin. Invest. 110 2002 493 497
    • (2002) J. Clin. Invest. , vol.110 , pp. 493-497
    • Becher, B.1    Durell, B.G.2    Noelle, R.J.3
  • 35
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • D.J. Cua, J. Sherlock, Y. Chen, C.A. Murphy, B. Joyce, and B. Seymour Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain Nature 421 2003 744 748
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3    Murphy, C.A.4    Joyce, B.5    Seymour, B.6
  • 36
    • 0032211092 scopus 로고    scopus 로고
    • Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis
    • C.S. Constantinescu, M. Wysocka, B. Hilliard, E.S. Ventura, E. Lavi, and G. Trinchieri Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis J. Immunol. 161 1998 5097 5104
    • (1998) J. Immunol. , vol.161 , pp. 5097-5104
    • Constantinescu, C.S.1    Wysocka, M.2    Hilliard, B.3    Ventura, E.S.4    Lavi, E.5    Trinchieri, G.6
  • 37
    • 0028966091 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
    • J.P. Leonard, K.E. Waldburger, and S.J. Goldman Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12 J. Exp. Med. 181 1995 381 386
    • (1995) J. Exp. Med. , vol.181 , pp. 381-386
    • Leonard, J.P.1    Waldburger, K.E.2    Goldman, S.J.3
  • 38
    • 0037376761 scopus 로고    scopus 로고
    • IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity
    • L.V. Bagaeva, L.P. Williams, and B.M. Segal IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity J. Neuroimmunol. 137 2003 109 116
    • (2003) J. Neuroimmunol. , vol.137 , pp. 109-116
    • Bagaeva, L.V.1    Williams, L.P.2    Segal, B.M.3
  • 39
    • 0029788704 scopus 로고    scopus 로고
    • IL-12 unmasks latent autoimmune disease in resistant mice
    • B.M. Segal, and E.M. Shevach IL-12 unmasks latent autoimmune disease in resistant mice J. Exp. Med. 184 1996 771 775
    • (1996) J. Exp. Med. , vol.184 , pp. 771-775
    • Segal, B.M.1    Shevach, E.M.2
  • 40
    • 0031156982 scopus 로고    scopus 로고
    • Microbial products induce autoimmune disease by an IL-12-dependent pathway
    • B.M. Segal, D.M. Klinman, and E.M. Shevach Microbial products induce autoimmune disease by an IL-12-dependent pathway J. Immunol. 158 1997 5087 5090
    • (1997) J. Immunol. , vol.158 , pp. 5087-5090
    • Segal, B.M.1    Klinman, D.M.2    Shevach, E.M.3
  • 41
    • 0034043957 scopus 로고    scopus 로고
    • CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivo
    • B.M. Segal, J.T. Chang, and E.M. Shevach CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivo J. Immunol. 164 2000 5683 5688
    • (2000) J. Immunol. , vol.164 , pp. 5683-5688
    • Segal, B.M.1    Chang, J.T.2    Shevach, E.M.3
  • 42
    • 0033560023 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells
    • J.T. Chang, E.M. Shevach, and B.M. Segal Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells J. Exp. Med. 189 1999 969 978
    • (1999) J. Exp. Med. , vol.189 , pp. 969-978
    • Chang, J.T.1    Shevach, E.M.2    Segal, B.M.3
  • 44
    • 0031027581 scopus 로고    scopus 로고
    • Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4+ T cells via CD40 ligand
    • K.E. Balashov, D.R. Smith, S.J. Khoury, D.A. Hafler, and H.L. Weiner Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand Proc. Natl. Acad. Sci. U. S. A. 94 1997 599 603
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 599-603
    • Balashov, K.E.1    Smith, D.R.2    Khoury, S.J.3    Hafler, D.A.4    Weiner, H.L.5
  • 45
    • 0032528896 scopus 로고    scopus 로고
    • Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy
    • M. Comabella, K. Balashov, S. Issazadeh, D. Smith, H.L. Weiner, and S.J. Khoury Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy J. Clin. Invest. 102 1998 671 678
    • (1998) J. Clin. Invest. , vol.102 , pp. 671-678
    • Comabella, M.1    Balashov, K.2    Issazadeh, S.3    Smith, D.4    Weiner, H.L.5    Khoury, S.J.6
  • 46
    • 0032975730 scopus 로고    scopus 로고
    • Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
    • A.H. van Boxel-Dezaire, S.C. Hoff, B.W. van Oosten, C.L. Verweij, A.M. Drager, and H.J. Ader Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis Ann. Neurol. 45 1999 695 703
    • (1999) Ann. Neurol. , vol.45 , pp. 695-703
    • Van Boxel-Dezaire, A.H.1    Hoff, S.C.2    Van Oosten, B.W.3    Verweij, C.L.4    Drager, A.M.5    Ader, H.J.6
  • 47
    • 0031721520 scopus 로고    scopus 로고
    • Increased release of interleukin-12p40 in MS: Association with intracerebral inflammation
    • K. Fassbender, A. Ragoschke, S. Rossol, A. Schwartz, O. Mielke, and A. Paulig Increased release of interleukin-12p40 in MS: association with intracerebral inflammation Neurology 51 1998 753 758
    • (1998) Neurology , vol.51 , pp. 753-758
    • Fassbender, K.1    Ragoschke, A.2    Rossol, S.3    Schwartz, A.4    Mielke, O.5    Paulig, A.6
  • 48
    • 1642458745 scopus 로고    scopus 로고
    • The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis
    • N. Kawakami, S. Lassmann, Z. Li, F. Odoardi, T. Ritter, and T. Ziemssen The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis J. Exp. Med. 199 2004 185 197
    • (2004) J. Exp. Med. , vol.199 , pp. 185-197
    • Kawakami, N.1    Lassmann, S.2    Li, Z.3    Odoardi, F.4    Ritter, T.5    Ziemssen, T.6
  • 49
    • 0025127157 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes. I: Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis
    • A.H. Cross, B. Cannella, C.F. Brosnan, and C.S. Raine Homing to central nervous system vasculature by antigen-specific lymphocytes. I: Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis Lab. Invest. 63 1990 162 170
    • (1990) Lab. Invest. , vol.63 , pp. 162-170
    • Cross, A.H.1    Cannella, B.2    Brosnan, C.F.3    Raine, C.S.4
  • 50
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • W.J. Karpus, N.W. Lukacs, B.L. McRae, R.M. Strieter, S.L. Kunkel, and S.D. Miller An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis J. Immunol. 155 1995 5003 5010
    • (1995) J. Immunol. , vol.155 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Strieter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 51
    • 0030613627 scopus 로고    scopus 로고
    • MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation
    • W.J. Karpus, and K.J. Kennedy MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation J. Leukoc. Biol. 62 1997 681 687
    • (1997) J. Leukoc. Biol. , vol.62 , pp. 681-687
    • Karpus, W.J.1    Kennedy, K.J.2
  • 52
    • 0032530033 scopus 로고    scopus 로고
    • Chemokine regulation of experimental autoimmune encephalomyelitis: Temporal and spatial expression patterns govern disease pathogenesis
    • W.J. Karpus, and R.M. Ransohoff Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis J. Immunol. 161 1998 2667 2671
    • (1998) J. Immunol. , vol.161 , pp. 2667-2671
    • Karpus, W.J.1    Ransohoff, R.M.2
  • 53
    • 8344236051 scopus 로고    scopus 로고
    • Chemokine regulation of immune-mediated demyelinating disease
    • W.J. Karpus, K.J. Kennedy, B.T. Fife, and L.M. Hoffman Chemokine regulation of immune-mediated demyelinating disease ILAR J. 40 1999 183 189
    • (1999) ILAR J. , vol.40 , pp. 183-189
    • Karpus, W.J.1    Kennedy, K.J.2    Fife, B.T.3    Hoffman, L.M.4
  • 54
    • 0033807680 scopus 로고    scopus 로고
    • CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
    • B.T. Fife, G.B. Huffnagle, W.A. Kuziel, and W.J. Karpus CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis J. Exp. Med. 192 2000 899 905
    • (2000) J. Exp. Med. , vol.192 , pp. 899-905
    • Fife, B.T.1    Huffnagle, G.B.2    Kuziel, W.A.3    Karpus, W.J.4
  • 55
    • 0033748655 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions
    • L.A. Boven, L. Montagne, H.S. Nottet, and C.J. De Groot Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions Clin. Exp. Immunol. 122 2000 257 263
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 257-263
    • Boven, L.A.1    Montagne, L.2    Nottet, H.S.3    De Groot, C.J.4
  • 56
    • 0033559346 scopus 로고    scopus 로고
    • Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
    • T.L. Sorensen, M. Tani, J. Jensen, V. Pierce, C. Lucchinetti, and V.A. Folcik Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients J. Clin. Invest. 103 1999 807 815
    • (1999) J. Clin. Invest. , vol.103 , pp. 807-815
    • Sorensen, T.L.1    Tani, M.2    Jensen, J.3    Pierce, V.4    Lucchinetti, C.5    Folcik, V.A.6
  • 57
    • 0035157253 scopus 로고    scopus 로고
    • CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis
    • C. Trebst, T.L. Sorensen, P. Kivisakk, M.K. Cathcart, J. Hesselgesser, and R. Horuk CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis Am. J. Pathol. 159 2001 1701 1710
    • (2001) Am. J. Pathol. , vol.159 , pp. 1701-1710
    • Trebst, C.1    Sorensen, T.L.2    Kivisakk, P.3    Cathcart, M.K.4    Hesselgesser, J.5    Horuk, R.6
  • 58
    • 0036275625 scopus 로고    scopus 로고
    • Multiple sclerosis: A study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system
    • T.L. Sorensen, C. Trebst, P. Kivisakk, K.L. Klaege, A. Majmudar, and R. Ravid Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system J. Neuroimmunol. 127 2002 59 68
    • (2002) J. Neuroimmunol. , vol.127 , pp. 59-68
    • Sorensen, T.L.1    Trebst, C.2    Kivisakk, P.3    Klaege, K.L.4    Majmudar, A.5    Ravid, R.6
  • 59
    • 0034055609 scopus 로고    scopus 로고
    • Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions
    • J.E. Simpson, J. Newcombe, M.L. Cuzner, and M.N. Woodroofe Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions Neuropathol. Appl. Neurobiol. 26 2000 133 142
    • (2000) Neuropathol. Appl. Neurobiol. , vol.26 , pp. 133-142
    • Simpson, J.E.1    Newcombe, J.2    Cuzner, M.L.3    Woodroofe, M.N.4
  • 60
    • 0035874640 scopus 로고    scopus 로고
    • CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis
    • B.T. Fife, K.J. Kennedy, M.C. Paniagua, N.W. Lukacs, S.L. Kunkel, and A.D. Luster CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis J. Immunol. 166 2001 7617 7624
    • (2001) J. Immunol. , vol.166 , pp. 7617-7624
    • Fife, B.T.1    Kennedy, K.J.2    Paniagua, M.C.3    Lukacs, N.W.4    Kunkel, S.L.5    Luster, A.D.6
  • 61
    • 0033536062 scopus 로고    scopus 로고
    • CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions
    • K.E. Balashov, J.B. Rottman, H.L. Weiner, and W.W. Hancock CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions Proc. Natl. Acad. Sci. U. S. A. 96 1999 6873 6878
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 6873-6878
    • Balashov, K.E.1    Rottman, J.B.2    Weiner, H.L.3    Hancock, W.W.4
  • 62
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • J.G. Cyster Chemokines and cell migration in secondary lymphoid organs Science 286 1999 2098 2102
    • (1999) Science , vol.286 , pp. 2098-2102
    • Cyster, J.G.1
  • 63
    • 0036687120 scopus 로고    scopus 로고
    • Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis
    • C. Alt, M. Laschinger, and B. Engelhardt Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis Eur. J. Immunol. 32 2002 2133 2144
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2133-2144
    • Alt, C.1    Laschinger, M.2    Engelhardt, B.3
  • 64
    • 0037248807 scopus 로고    scopus 로고
    • Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: Implications for the maintenance of chronic neuroinflammation
    • S. Columba-Cabezas, B. Serafini, E. Ambrosini, and F. Aloisi Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: implications for the maintenance of chronic neuroinflammation Brain Pathol. 13 2003 38 51
    • (2003) Brain Pathol. , vol.13 , pp. 38-51
    • Columba-Cabezas, S.1    Serafini, B.2    Ambrosini, E.3    Aloisi, F.4
  • 65
    • 1242340285 scopus 로고    scopus 로고
    • Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis
    • R. Magliozzi, S. Columba-Cabezas, B. Serafini, and F. Aloisi Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis J. Neuroimmunol. 148 2004 11 23
    • (2004) J. Neuroimmunol. , vol.148 , pp. 11-23
    • Magliozzi, R.1    Columba-Cabezas, S.2    Serafini, B.3    Aloisi, F.4
  • 66
    • 0037308663 scopus 로고    scopus 로고
    • Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation
    • M. Pashenkov, M. Soderstrom, and H. Link Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation J. Neuroimmunol. 135 2003 154 160
    • (2003) J. Neuroimmunol. , vol.135 , pp. 154-160
    • Pashenkov, M.1    Soderstrom, M.2    Link, H.3
  • 67
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • B. Serafini, B. Rosicarelli, R. Magliozzi, E. Stigliano, and F. Aloisi Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis Brain Pathol. 14 2004 164 174
    • (2004) Brain Pathol. , vol.14 , pp. 164-174
    • Serafini, B.1    Rosicarelli, B.2    Magliozzi, R.3    Stigliano, E.4    Aloisi, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.