Macrophage inflammatory protein-1α (MIP-1α), MIP-1β, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions

Clinical and Experimental Immunology

Volumn 122, Issue 2, 2000, Pages 257-263

  Boven, L A ^a   Montagne, L ^a,b   Nottet, H S L M ^a   De Groot, C J A ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Astrocytes; CC chemokines; Immunohistochemistry; Macrophages; Reverse transcriptase polymerase chain reaction

Indexed keywords

BETA CHEMOKINE; CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; RANTES;

ADULT; AGED; ARTICLE; ASTROCYTE; CELL MIGRATION; DEMYELINATING DISEASE; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTIC INFILTRATION; MALE; MICROGLIA; MULTIPLE SCLEROSIS; MYELIN DEFICIENCY; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; BRAIN; CASE-CONTROL STUDIES; DNA PRIMERS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RANTES; RNA, MESSENGER;

EID: 0033748655     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01334.x     Document Type: Article

References (34)

1. Molecular properties of the chemokine receptor family
2. Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody
3. The immunopathology of chemotactic cytokines: The role of interleukin-8 and monocyte chemoattractant protein-1
4. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia
5. Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: Implications for recruitment of leukocytes into brain and lymph nodes
6. Perivascular T cells express the pro-inflammatory chemokine RANTES mRNA in multiple sclerosis lesions
7. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: An immunohistochemical and in situ hybridization study
8. The cellular immunology of multiple sclerosis
9. Mechanisms of immune injury in multiple sclerosis
10. Phagocytic activity of macrophages and microglial cells during acute and chronic relapsing experimental autoimmune encephalomyelitis
11. Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions
12. Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions
13. Macrophage inflammatory protein-1 alpha in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases
14. Increased peroxynitrite activity in AIDS Dementia Complex: Implications for the neuropathogenesis of HIV-1 infection
15. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
16. Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis
17. Cytokine expression in the brain during the acquired immunodeficiency syndrome
18. Cytokine secretion and nitric oxide production by mononuclear cells of patients with multiple sclerosis
19. The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis
20. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
21. Enhanced expression of MMP-7 and MMP-9 in demyelinating multiple sclerosis lesions
22. Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions
23. Brain macrophages: Neurotoxic or neurotrophic effector cells?
24. Regulation of oligodendrocyte differentiation by fibroblast growth factors
25. Macrophages in CNS remyelination: Friend or foe?
26. Protein growth factors as potential therapies for central nervous system demyelinative disorders
27. Growth factors and myelin regeneration in multiple sclerosis
28. Chemokines and tissue injury
29. Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro
30. RANTES and MIP-1alpha activate stats in T cells
31. CCR5 (+) and CXCR3 (+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions
32. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
33. Induction of RANTES expression by astrocytes and astrocytoma cell lines
34. Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia