메뉴 건너뛰기




Volumn 28, Issue 5, 2003, Pages 465-474

The roles of Rab27 and its effectors in the regulated secretory pathways

Author keywords

Granuphilin; Lysosome related organelle; Melanophilin; Rab27; Regulated secretion; Secretory granule

Indexed keywords

BINDING PROTEIN; GRANUPHILIN; GUANOSINE TRIPHOSPHATASE; MELANOPHILIN; MYOSIN V; RAB PROTEIN; RAB27 PROTEIN; SYNTAXIN; UNCLASSIFIED DRUG;

EID: 1342310841     PISSN: 03867196     EISSN: None     Source Type: Journal    
DOI: 10.1247/csf.28.465     Document Type: Review
Times cited : (105)

References (68)
  • 4
    • 0035379643 scopus 로고    scopus 로고
    • JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase
    • Berkowitz, J.K.M., Catz, S.D., Johnson, J.L., Ruedi, J.M., Thon, V., and Babior, B.M. 2001. JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. J. Biol. Chem., 276: 18855-18862.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18855-18862
    • Berkowitz, J.K.M.1    Catz, S.D.2    Johnson, J.L.3    Ruedi, J.M.4    Thon, V.5    Babior, B.M.6
  • 6
    • 0035865345 scopus 로고    scopus 로고
    • A genomic perspective on membrane compartment organization
    • Bock, J.B., Matern, H.T., Peden, A.A., and Scheller, R.H. 2001. A genomic perspective on membrane compartment organization. Nature, 409: 839-841.
    • (2001) Nature , vol.409 , pp. 839-841
    • Bock, J.B.1    Matern, H.T.2    Peden, A.A.3    Scheller, R.H.4
  • 7
    • 0023463127 scopus 로고
    • Constitutive and regulated secretion of proteins
    • Burgess, T.L. and Kelly, R.B. 1987. Constitutive and regulated secretion of proteins. Annu. Rev. Cell Biol., 3: 243-293.
    • (1987) Annu. Rev. Cell Biol. , vol.3 , pp. 243-293
    • Burgess, T.L.1    Kelly, R.B.2
  • 9
    • 0037015063 scopus 로고    scopus 로고
    • The C2A domain of JFC1 binds to 3′-phosphorylated phosphoinositides and directs plasma membrane association in living cells
    • Catz, S.D., Johnson, J.L., and Babior, B.M. 2002. The C2A domain of JFC1 binds to 3′-phosphorylated phosphoinositides and directs plasma membrane association in living cells. Proc. Natl. Acad Sci., USA, 99: 11652-11657.
    • (2002) Proc. Natl. Acad Sci., USA , vol.99 , pp. 11652-11657
    • Catz, S.D.1    Johnson, J.L.2    Babior, B.M.3
  • 10
    • 0026550828 scopus 로고
    • Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells
    • Chow, R.H., von Rüden, L., and Neher, E. 1992. Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells. Nature, 356: 60-63.
    • (1992) Nature , vol.356 , pp. 60-63
    • Chow, R.H.1    von Rüden, L.2    Neher, E.3
  • 11
    • 0035985165 scopus 로고    scopus 로고
    • Prancreatic β-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis
    • Coppola, T., Frantz, C., Perret-Menoud, V., Gattesco, S., Hirling, H., and Regazzi, R. 2002. Prancreatic β-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis. Mol. Biol. Cell, 13: 1906-1915.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1906-1915
    • Coppola, T.1    Frantz, C.2    Perret-Menoud, V.3    Gattesco, S.4    Hirling, H.5    Regazzi, R.6
  • 15
    • 0035849901 scopus 로고    scopus 로고
    • Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway
    • Eggenschwiler, J.T., Espinoza, E., and Anderson, K.V. 2001. Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature, 412: 194-198.
    • (2001) Nature , vol.412 , pp. 194-198
    • Eggenschwiler, J.T.1    Espinoza, E.2    Anderson, K.V.3
  • 17
    • 0028309740 scopus 로고
    • Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis
    • Fischer von Mollard, G., Stahl, B., Khokhlatchev, A., Südhof, T.C., and Jahn, R. 1994. Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis. J. Biol. Chem., 269: 10971-10974.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10971-10974
    • Fischer von Mollard, G.1    Stahl, B.2    Khokhlatchev, A.3    Südhof, T.C.4    Jahn, R.5
  • 18
    • 0037131296 scopus 로고    scopus 로고
    • Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A
    • Fukuda, M. 2002. Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A. J. Biol. Chem., 277: 40118-40124.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40118-40124
    • Fukuda, M.1
  • 19
    • 0037044819 scopus 로고    scopus 로고
    • Slac2-c (Synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin
    • Fukuda, M. and Kuroda, T.S. 2002. Slac2-c (Synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin. J. Biol. Chem., 277: 43096-43103.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43096-43103
    • Fukuda, M.1    Kuroda, T.S.2
  • 20
    • 0037023745 scopus 로고    scopus 로고
    • Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: Implication of a tripartite protein complex for melanosome transport
    • Fukuda, M., Kuroda, T.S., and Mikoshiba, K. 2002. Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implication of a tripartite protein complex for melanosome transport. J. Biol. Chem., 277: 12432-12436.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12432-12436
    • Fukuda, M.1    Kuroda, T.S.2    Mikoshiba, K.3
  • 21
    • 0034805325 scopus 로고    scopus 로고
    • Synaptotagmin-like protein 1-3: A novel family of C-terminal-type tandem C2 proteins
    • Fukuda, M. and Mikoshiba, K. 2001. Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins. Biochem. Biophys. Res. Commun., 281: 1226-1233.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 1226-1233
    • Fukuda, M.1    Mikoshiba, K.2
  • 24
    • 0030980279 scopus 로고    scopus 로고
    • The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
    • Geppert, M., Goda, Y., Stevens, C.F., and Südhof, T.C. 1997. The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion. Nature, 387: 810-814.
    • (1997) Nature , vol.387 , pp. 810-814
    • Geppert, M.1    Goda, Y.2    Stevens, C.F.3    Südhof, T.C.4
  • 25
    • 0035911150 scopus 로고    scopus 로고
    • Defective granule exocytosis in Rab27a-deficient lymphocytes from ashen mice
    • Haddad, E.K., Wu, X., Hammer III, J.A., and Henkart, P.A. 2001. Defective granule exocytosis in Rab27a-deficient lymphocytes from ashen mice. J. Cell Biol., 152: 835-841.
    • (2001) J. Cell Biol. , vol.152 , pp. 835-841
    • Haddad, E.K.1    Wu, X.2    Hammer III, J.A.3    Henkart, P.A.4
  • 26
    • 0027364502 scopus 로고
    • Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
    • Hata, Y., Slaughter, C.A., and Südhof, C. 1993. Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature, 366: 347-351.
    • (1993) Nature , vol.366 , pp. 347-351
    • Hata, Y.1    Slaughter, C.A.2    Südhof, C.3
  • 29
    • 0032836484 scopus 로고    scopus 로고
    • Membrane fusion and exocytosis
    • Jahn, R. and Südhof, T.C. 1999. Membrane fusion and exocytosis. Annu. Rev. Biochem., 68: 863-911.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 863-911
    • Jahn, R.1    Südhof, T.C.2
  • 32
    • 0037088641 scopus 로고    scopus 로고
    • The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain
    • Kuroda, T.S., Fukuda, M., Ariga, H., and Mikoshiba, K. 2002a. The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J. Biol. Chem., 277: 9212-9218.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9212-9218
    • Kuroda, T.S.1    Fukuda, M.2    Ariga, H.3    Mikoshiba, K.4
  • 33
    • 0036298197 scopus 로고    scopus 로고
    • Synaptotagmin-like protein 5: A novel Rab27a effector with C-terminal tandem C2 domains
    • Kuroda, T.S., Fukuda, M., Ariga, H., and Mikoshiba, K. 2002b. Synaptotagmin-like protein 5: a novel Rab27a effector with C-terminal tandem C2 domains. Biochem. Biophys. Res. Commun., 293: 899-906.
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , pp. 899-906
    • Kuroda, T.S.1    Fukuda, M.2    Ariga, H.3    Mikoshiba, K.4
  • 35
    • 0032214487 scopus 로고    scopus 로고
    • Mechanism of action of rab3A in mossy fiber LTP
    • Lonart, G., Janz, R., Johnson, K.M., and Südhof, T.C. 1998. Mechanism of action of rab3A in mossy fiber LTP. Neuron, 21: 1141-1150.
    • (1998) Neuron , vol.21 , pp. 1141-1150
    • Lonart, G.1    Janz, R.2    Johnson, K.M.3    Südhof, T.C.4
  • 36
    • 0035490904 scopus 로고    scopus 로고
    • The melanosome: Membrane dynamics in black and white
    • Marks, M.S. and Seabra, M.C. 2001. The melanosome: membrane dynamics in black and white. Nat. Rev. Mol. Cell Biol., 2: 1-11.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 1-11
    • Marks, M.S.1    Seabra, M.C.2
  • 39
    • 0024059809 scopus 로고
    • The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and In
    • Moore, K.J., Swing, D.A., Rinchik, E.M., Mucenski, M.L., Buchberg, A.M., Copeland, N.G., and Jenkins, N.A. 1988. The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and In. Genetics, 119: 933-941.
    • (1988) Genetics , vol.119 , pp. 933-941
    • Moore, K.J.1    Swing, D.A.2    Rinchik, E.M.3    Mucenski, M.L.4    Buchberg, A.M.5    Copeland, N.G.6    Jenkins, N.A.7
  • 40
    • 0037165662 scopus 로고    scopus 로고
    • Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions
    • Nagashima, K., Torii, S., Yi, Z., Igarashi, M., Okamoto, K., Takeuchi, T., and Izumi, T. 2002. Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions. FEBS Lett., 517: 233-238.
    • (2002) FEBS Lett. , vol.517 , pp. 233-238
    • Nagashima, K.1    Torii, S.2    Yi, Z.3    Igarashi, M.4    Okamoto, K.5    Takeuchi, T.6    Izumi, T.7
  • 41
    • 0036660163 scopus 로고    scopus 로고
    • The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background
    • Novak, E.K., Gautam, R., Reddington, M., Collinson, L.M., Copeland, N.G., Jenkins, N.A., McGarry, M.P., and Swank, R.T. 2002. The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background. Blood, 100: 128-135.
    • (2002) Blood , vol.100 , pp. 128-135
    • Novak, E.K.1    Gautam, R.2    Reddington, M.3    Collinson, L.M.4    Copeland, N.G.5    Jenkins, N.A.6    McGarry, M.P.7    Swank, R.T.8
  • 42
    • 0033525215 scopus 로고    scopus 로고
    • Structural basis of Rab effector specificity: Crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A
    • Ostermeier, C. and Brunger, A.T. 1999. Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. Cell, 96: 363-374.
    • (1999) Cell , vol.96 , pp. 363-374
    • Ostermeier, C.1    Brunger, A.T.2
  • 43
    • 0035798385 scopus 로고    scopus 로고
    • Evolution of the Rab family of small GTP-binding proteins
    • Pereira-Leal, J.B. and Seabra, M.C. 2001. Evolution of the Rab family of small GTP-binding proteins. J. Mol. Biol., 313: 889-901.
    • (2001) J. Mol. Biol. , vol.313 , pp. 889-901
    • Pereira-Leal, J.B.1    Seabra, M.C.2
  • 44
    • 2342547690 scopus 로고    scopus 로고
    • Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models
    • Ramalho, J.S., Anders, R., Jaissle, G.B., Seeliger, M.W., Huxley, C., and Seabra, M.C. 2002. Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models. BMC Cell Biol., 3: 26.
    • (2002) BMC Cell Biol. , vol.3 , pp. 26
    • Ramalho, J.S.1    Anders, R.2    Jaissle, G.B.3    Seeliger, M.W.4    Huxley, C.5    Seabra, M.C.6
  • 48
    • 0036673069 scopus 로고    scopus 로고
    • SNAREs and Munc18 in synaptic vesicle fusion
    • Rizo, J. and Südhof, T.C. 2002. SNAREs and Munc18 in synaptic vesicle fusion. Nat. Rev. Neurosci., 3: 641-653.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 641-653
    • Rizo, J.1    Südhof, T.C.2
  • 49
    • 0029990813 scopus 로고    scopus 로고
    • Timing of neurotransmission at fast synapses in the mammalian brain
    • Sabatini, B. and Regehr, W.G. 1996. Timing of neurotransmission at fast synapses in the mammalian brain. Nature, 384: 170-172.
    • (1996) Nature , vol.384 , pp. 170-172
    • Sabatini, B.1    Regehr, W.G.2
  • 50
    • 0028822704 scopus 로고
    • Deficient geranylgeranylation of Ram/Rab27 in choroideremia
    • Seabra, M.C., Ho, Y.K., and Anant, J.S. 1995. Deficient geranylgeranylation of Ram/Rab27 in choroideremia. J. Biol. Chem., 270: 24220-24227.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24220-24227
    • Seabra, M.C.1    Ho, Y.K.2    Anant, J.S.3
  • 51
    • 0035425411 scopus 로고    scopus 로고
    • Ypt and Rab GTPases: Insight into functions through novel interactions
    • Segev, N. 2001. Ypt and Rab GTPases: insight into functions through novel interactions. Curr. Opin. Cell Biol., 13: 500-511.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 500-511
    • Segev, N.1
  • 52
    • 0029056416 scopus 로고
    • Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner
    • Seperack, P.K., Mercer, J.A., Strobel, M.C., Copelamd, N.G., and Jenkins, N.A. 1995. Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner. EMBO J., 14: 2326-2332.
    • (1995) EMBO J. , vol.14 , pp. 2326-2332
    • Seperack, P.K.1    Mercer, J.A.2    Strobel, M.C.3    Copelamd, N.G.4    Jenkins, N.A.5
  • 53
    • 0027461829 scopus 로고
    • Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin
    • Shirataki, H., Kaibuchi, K., Sakota, T., Kishida, S., Yamaguchi, T., Wada, K., Miyazaki, M., and Takai, Y. 1993. Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin. Mol. Cell Biol., 13: 2061-2068.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2061-2068
    • Shirataki, H.1    Kaibuchi, K.2    Sakota, T.3    Kishida, S.4    Yamaguchi, T.5    Wada, K.6    Miyazaki, M.7    Takai, Y.8
  • 55
    • 0037067673 scopus 로고    scopus 로고
    • A family of Rab27-binding proteins: Melanophilin links Rab27a and myosin Va function in melanosome transport
    • Strom, M., Hume, A.N., Tarafder, A.K., Barkagianni, E., and Seabra, M.C. 2002. A family of Rab27-binding proteins: melanophilin links Rab27a and myosin Va function in melanosome transport. J. Biol. Chem., 277: 25423-25430.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25423-25430
    • Strom, M.1    Hume, A.N.2    Tarafder, A.K.3    Barkagianni, E.4    Seabra, M.C.5
  • 56
    • 0029026392 scopus 로고
    • The synaptic vesicle cycle: A cascade of protein-protein interactions
    • Südhof, T.C. 1995. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature, 375: 645-653.
    • (1995) Nature , vol.375 , pp. 645-653
    • Südhof, T.C.1
  • 58
    • 0036314198 scopus 로고    scopus 로고
    • Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a
    • Torii, S., Zhao, S., Yi, Z., Takeuchi, T., and Izumi, T. 2002. Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. Mol. Cell Biol., 22: 5518-5526.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 5518-5526
    • Torii, S.1    Zhao, S.2    Yi, Z.3    Takeuchi, T.4    Izumi, T.5
  • 60
    • 0033214974 scopus 로고    scopus 로고
    • Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells
    • Wang, J., Takeuchi, T., Yokota, H., and Izumi, T. 1999. Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells. J. Biol. Chem., 274: 28542-28548.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28542-28548
    • Wang, J.1    Takeuchi, T.2    Yokota, H.3    Izumi, T.4
  • 61
    • 0035980002 scopus 로고    scopus 로고
    • Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal α-helix motifs
    • Wang, X., Hu, B., Zimmermann, B., and Kilimann, M.W. 2001. Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal α-helix motifs. J. Biol. Chem., 276: 32480-32488.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32480-32488
    • Wang, X.1    Hu, B.2    Zimmermann, B.3    Kilimann, M.W.4
  • 63
    • 0032576622 scopus 로고    scopus 로고
    • Visualization of melanosome dynamics within wild-type and dilute melanocytes suggest a paradigm for myosin V function in vivo
    • Wu, X., Bowers, B., Rao, K., Wei, Q., and Hammer III, J.A. 1998. Visualization of melanosome dynamics within wild-type and dilute melanocytes suggest a paradigm for myosin V function in vivo. J. Cell Biol., 143: 1899-1918.
    • (1998) J. Cell Biol. , vol.143 , pp. 1899-1918
    • Wu, X.1    Bowers, B.2    Rao, K.3    Wei, Q.4    Hammer III, J.A.5
  • 66
    • 0036181537 scopus 로고    scopus 로고
    • The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules
    • Yi, Z., Yokota, H., Torii, S., Aoki, T., Hosaka, M., Zhao, S., Takata, K., Takeuchi, T., and Izumi, T. 2002. The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules. Mol. Cell Biol., 22: 1858-1867.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1858-1867
    • Yi, Z.1    Yokota, H.2    Torii, S.3    Aoki, T.4    Hosaka, M.5    Zhao, S.6    Takata, K.7    Takeuchi, T.8    Izumi, T.9
  • 67
  • 68
    • 0036230738 scopus 로고    scopus 로고
    • Involvement of Rab27b in the regulated secretion of pituitary hormones
    • Zhao, S., Torii, S., Yokota-Hashimoto, H., Takeuchi, T., and Izumi, T. 2002. Involvement of Rab27b in the regulated secretion of pituitary hormones. Endocrinol., 143: 1817-1824.
    • (2002) Endocrinol. , vol.143 , pp. 1817-1824
    • Zhao, S.1    Torii, S.2    Yokota-Hashimoto, H.3    Takeuchi, T.4    Izumi, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.