Beta-cell replacement technologies: The potential of stem cells

Drug Discovery Today: Therapeutic Strategies

Volumn 1, Issue 2, 2004, Pages 213-217

  Jones, Peter M ^a   Burns, Christopher J ^a   Persaud, Shanta J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; HELIX LOOP HELIX PROTEIN; INSULIN; TRANSCRIPTION FACTOR PDX 1;

ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; EMBRYONIC STEM CELL; ENCAPSULATION; HUMAN; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; LIVER CELL; MEDICAL TECHNOLOGY; NEURAL STEM CELL; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; XENOGRAFT;

EID: 13344277925     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2004.06.003     Document Type: Review

References (40)

1. A.M.J. Shapiro et al. Islet transplantation in seven patients with Type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regime N. Engl. J. Med. 343 2000 230-238
2. L.J.W. van der Laan et al. Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice Nature 407 2000 90-94
3. S. Bonner-Weir et al. In vitro cultivation of human islets from expanded ductal tissue Proc. Natl. Acad. Sci. USA 97 2000 7999-8004
4. V.K. Ramiya et al. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells Nat. Med. 6 2000 278-282
5. H. Zulewski et al. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes Diabetes 50 2001 521-533
6. E. Hunziker M. Stein Nestin-expressing cells in the pancreatic islets of Langerhans Biochem. Biophys. Res. Commun. 271 2000 116-119
7. L. Selander H. Edlund Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas Mech. Dev. 113 2002 189-219
8. N.A. Hanley Beta-cell differentiation during human development does not rely on nestin-positive precursors: Implications for stem cell-derived replacement therapy Diabetologia 45 2002 1045-1047
9. R.K. Humphrey et al. Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas Diabetes 52 2003 2519-2525
10. T. Klein et al. Nestin is expressed in vascular endothelial cells in the adult human pancreas J. Histochem. Cytochem. 51 2003 697-706
11. C.N. Street et al. Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker J. Endocrinol. 180 2004 213-225
12. Y. Dor et al. Adult pancreatic cells are formed by self-duplication rather than stem-cell differentiation Nature 429 2004 41-46
13. S. Ferber et al. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia Nat. Med. 6 2000 568-572
14. M. Horb et al. Experimental conversion of pancreas to liver Curr. Biol. 13 2003 105-115
15. H. Kojima et al. NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice Nat. Med. 9 2003 596-603
16. M. Zalzman et al. Reversal of hyperglycaemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells PNAS 100 2003 7253-7258
17. A. Suzuki et al. Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver J. Cell Biol. 156 2002 173-184
18. L. Yang et al. In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells PNAS 99 2002 8078-8083
19. D.L. Clarke et al. Generalized potential of adult neural stem cells Science 288 2002 1660-1663
20. U.H. Sang et al. Fetal brain progenitor cells transdifferentiate to fates outside the nervous system Mol. Endocrinol. 16 2002 2645-2656
21. M.E. Wilson et al. Gene expression cascades in pancreatic development Mech. Dev. 120 2003 65-80
22. S.U. Devasker et al. The developmental pattern of rabbit brain insulin and insulin-like growth factor receptor expression Brain Res. 605 1993 101-109
23. H. Jahr B. Bretzel Insulin-positive cells in vitro generated from rat bone marrow stromal cells Transplant. Proc. 35 2003 2140-2141
24. A. Ianus et al. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion J. Clin. Invest. 111 2003 843-850
25. V.M. Lee M. Stoffel Bone marrow: An extrapancreatic hideout for the elusive pancreatic stem cell? J. Clin. Invest. 111 2003 799-801
26. A.J. Wagers et al. Little evidence for developmental plasticity of adult hematopoietic stem cells Science 297 2002 2256-2259
27. N. Lumelsky et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets Science 292 2001 1389-1394
28. J. Rajagopal et al. Insulin staining of ES cell progeny from insulin uptake Science 299 2003 363
29. Y. Hori et al. Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells Proc. Natl. Acad. Sci. USA 99 2002 16105-16110
30. A. Shiroi et al. Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone Stem Cells 20 2002 284-292
31. P. Blyszczuk et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells Proc. Natl. Acad. Sci. USA 100 2003 998-1003
32. S. Miyazaki et al. Regulated expression of PDX-1 promotes in vitro differentiation of insulin producing cells from embryonic stem cells Diabetes 53 2004 1030-1037
33. S. Sipione et al. Insulin expressing cells from differentiated embryonic stem cells are not beta cells Diabetologia 47 2004 499-508
34. B. Soria et al. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice Diabetes 49 2000 157-162
35. N. Houard et al. HNF-6-independent differentiation of mouse embryonic stem cells into insulin-producing cells Diabetologia 46 2003 378-385
36. S. Assady et al. Insulin production by human embryonic stem cells Diabetes 50 2001 1691-1697
37. H. Segev et al. Differentiation of human embryonic stem cells into insulin producing clusters Stem Cells 22 2004 265-274
38. K. Rau et al. Insulin-gene expression in extrafetal membranes of rats Diabetes 38 1989 39-43
39. D-Q. Tang et al. In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow Diabetes 53 2004 1721-1732
40. T. Leon-Quinto et al. In vitro directed differentiation of mouse embryonic stem cells into insulin producing cells Diabetologia 47 2004 1442-1451