-
1
-
-
0042737910
-
Low high density lipoprotein cholesterol - Physiological background, clinical importance and drug treatment
-
M. Hersberger A. von Eckardstein Low high density lipoprotein cholesterol - physiological background, clinical importance and drug treatment Drugs 63 2003 1907-1945
-
(2003)
Drugs
, vol.63
, pp. 1907-1945
-
-
Hersberger, M.1
von Eckardstein, A.2
-
2
-
-
0035170229
-
High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport
-
A. von Eckardstein et al. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport Arterioscler. Thromb. Vasc. Biol. 21 2001 13-27
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 13-27
-
-
von Eckardstein, A.1
-
3
-
-
0037339775
-
Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome
-
G.F. Watts et al. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome Diabetes 52 2003 803-811
-
(2003)
Diabetes
, vol.52
, pp. 803-811
-
-
Watts, G.F.1
-
4
-
-
0842282977
-
Effects of atorvastatin versus fenofibrate on apoB-100 and apoA-I kinetics in mixed hyperlipidemia
-
S. Bilz et al. Effects of atorvastatin versus fenofibrate on apoB-100 and apoA-I kinetics in mixed hyperlipidemia J. Lipid Res. 45 2004 174-185
-
(2004)
J. Lipid Res.
, vol.45
, pp. 174-185
-
-
Bilz, S.1
-
5
-
-
0036727448
-
The role of PPARs in atherosclerosis
-
C. Duval et al. The role of PPARs in atherosclerosis Trends Mol. Med. 9 2002 422-430
-
(2002)
Trends Mol. Med.
, vol.9
, pp. 422-430
-
-
Duval, C.1
-
6
-
-
2442711384
-
Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
-
N. Marx et al. Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells Circ. Res. 94 2004 168-178
-
(2004)
Circ. Res.
, vol.94
, pp. 168-178
-
-
Marx, N.1
-
7
-
-
0034994075
-
Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I
-
G. Martin et al. Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I J. Clin. Invest. 107 2001 1423-1432
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1423-1432
-
-
Martin, G.1
-
8
-
-
0033668998
-
Prevention of coronary heart disease by raising of HDL cholesterol?
-
A. von Eckardstein G. Assmann Prevention of coronary heart disease by raising of HDL cholesterol? Curr. Opin. Lipidol. 11 2000 627-637
-
(2000)
Curr. Opin. Lipidol.
, vol.11
, pp. 627-637
-
-
von Eckardstein, A.1
Assmann, G.2
-
9
-
-
1442326015
-
Transcriptional control of apolipoprotein A-I gene expression in diabetes
-
A.D. Mooradian et al. Transcriptional control of apolipoprotein A-I gene expression in diabetes Diabetes 53 2004 513-520
-
(2004)
Diabetes
, vol.53
, pp. 513-520
-
-
Mooradian, A.D.1
-
10
-
-
0842282981
-
Regulation of apoA-I gene expression: Mechanism of action of estrogen and genistein
-
S. Lamon-Fava D. Micherone Regulation of apoA-I gene expression: mechanism of action of estrogen and genistein J. Lipid Res. 45 2004 106-112
-
(2004)
J. Lipid Res.
, vol.45
, pp. 106-112
-
-
Lamon-Fava, S.1
Micherone, D.2
-
11
-
-
4444266039
-
Alternative hormone replacement regimens: Is there a need for further clinical trials?
-
F.K. Welty Alternative hormone replacement regimens: Is there a need for further clinical trials? Curr. Opin. Lipidol. 14 2003 585-591
-
(2003)
Curr. Opin. Lipidol.
, vol.14
, pp. 585-591
-
-
Welty, F.K.1
-
12
-
-
0036218724
-
Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element
-
T. Claudel et al. Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element J. Clin. Invest. 109 2002 961-971
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 961-971
-
-
Claudel, T.1
-
13
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
G.A. Kullak-Ublick et al. Enterohepatic bile salt transporters in normal physiology and liver disease Gastroenterology 126 2004 322-342
-
(2004)
Gastroenterology
, vol.126
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
-
14
-
-
0003295132
-
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump
-
J. Cui et al. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump J. Biol. Chem. 278 2003 10214-10220
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10214-10220
-
-
Cui, J.1
-
15
-
-
0042160272
-
Guggulipid for the treatment of hypercholesterolemia: A randomized controlled trial
-
P.O. Szapary et al. Guggulipid for the treatment of hypercholesterolemia: A randomized controlled trial J. Am. Med. Assoc. 290 2003 765-772
-
(2003)
J. Am. Med. Assoc.
, vol.290
, pp. 765-772
-
-
Szapary, P.O.1
-
16
-
-
0042734464
-
Efflux and atherosclerosis: The clinical and biochemical impact of variations in the ABCA1 gene
-
R.R. Singaraja et al. Efflux and atherosclerosis: The clinical and biochemical impact of variations in the ABCA1 gene Arterioscler. Thromb. Vasc. Biol. 23 2003 1322-1332
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1322-1332
-
-
Singaraja, R.R.1
-
17
-
-
0038460073
-
Study of ABCA1 function in transgenic mice
-
C. Joyce et al. Study of ABCA1 function in transgenic mice Arterioscler. Thromb. Vasc. Biol. 23 2003 965-971
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 965-971
-
-
Joyce, C.1
-
18
-
-
0038448097
-
Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux
-
N. Wang A.R. Tall Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux Arterioscler. Thromb. Vasc. Biol. 23 2003 1178-1184
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1178-1184
-
-
Wang, N.1
Tall, A.R.2
-
19
-
-
0142123179
-
Retinoic acid receptor-mediated induction of ABCA1 in macrophages
-
P. Costet et al. Retinoic acid receptor-mediated induction of ABCA1 in macrophages Mol. Cell. Biol. 23 2003 7756-7766
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7756-7766
-
-
Costet, P.1
-
20
-
-
0037503924
-
Liver X receptor signaling pathways in cardiovascular disease
-
P. Tontonoz D.J. Mangelsdorf Liver X receptor signaling pathways in cardiovascular disease Mol. Endocrinol. 17 2003 985-993
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 985-993
-
-
Tontonoz, P.1
Mangelsdorf, D.J.2
-
21
-
-
1642300417
-
Apolipoprotein. A-I activates cellular cAMP signaling through the ABCA1 transporter
-
B. Haidar et al. Apolipoprotein. A-I activates cellular cAMP signaling through the ABCA1 transporter J. Biol. Chem. 279 2004 9963-9969
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9963-9969
-
-
Haidar, B.1
-
22
-
-
0036289296
-
Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux
-
G. Lin K.E. Bornfeldt Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux Biochem. Biophys. Res. Commun. 290 2002 663-669
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 663-669
-
-
Lin, G.1
Bornfeldt, K.E.2
-
23
-
-
1242322495
-
Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin
-
T. Rubic et al. Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin Biochem. Pharmacol. 67 2004 411-419
-
(2004)
Biochem. Pharmacol.
, vol.67
, pp. 411-419
-
-
Rubic, T.1
-
24
-
-
0141844589
-
Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I
-
L.O. Martinez et al. Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I J. Biol. Chem. 278 2003 37368-37374
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37368-37374
-
-
Martinez, L.O.1
-
25
-
-
0347918856
-
Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly
-
Y. Yamauchi et al. Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly J. Biol. Chem. 278 2003 47890-47897
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47890-47897
-
-
Yamauchi, Y.1
-
26
-
-
0347362786
-
Involvement of Cdc42 signaling in apoA-I-induced cholesterol efflux
-
J.R. Nofer et al. Involvement of Cdc42 signaling in apoA-I-induced cholesterol efflux J. Biol. Chem. 278 2003 53055-53062
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 53055-53062
-
-
Nofer, J.R.1
-
27
-
-
0037327033
-
Cholesteryl ester transfer protein: A novel target for raising HDL and inhibiting atherosclerosis
-
P.J. Barter et al. Cholesteryl ester transfer protein: A novel target for raising HDL and inhibiting atherosclerosis Arterioscler. Thromb. Vasc. Biol. 23 2003 160-167
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 160-167
-
-
Barter, P.J.1
-
28
-
-
0037035459
-
Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
-
G.J. de Grooth et al. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study Circulation 105 2002 2159-2165
-
(2002)
Circulation
, vol.105
, pp. 2159-2165
-
-
de Grooth, G.J.1
-
29
-
-
12144287356
-
Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: An initial multidose study of torcetrapib
-
R.W. Clark et al. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: An initial multidose study of torcetrapib Arterioscler. Thromb. Vasc. Biol. 24 2004 490-497
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 490-497
-
-
Clark, R.W.1
-
30
-
-
1842815777
-
Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol
-
M.E. Brousseau et al. Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol N. Engl. J. Med. 350 2004 1505-1515
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1505-1515
-
-
Brousseau, M.E.1
-
31
-
-
0034644214
-
A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
-
H. Okamoto et al. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits Nature 406 2000 203-207
-
(2000)
Nature
, vol.406
, pp. 203-207
-
-
Okamoto, H.1
-
32
-
-
0036907139
-
Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia
-
Z. Huang et al. Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia Clin. Sci. (Lond.) 103 2002 587-594
-
(2002)
Clin. Sci. (Lond.)
, vol.103
, pp. 587-594
-
-
Huang, Z.1
-
33
-
-
0141988913
-
Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis
-
B.L. Trigatti et al. Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis Arterioscler. Thromb. Vasc. Biol. 23 2003 1732-1738
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1732-1738
-
-
Trigatti, B.L.1
-
34
-
-
0041559836
-
HDL stimulation of endothelial nitric oxide synthase: A novel mechanism of HDL action
-
C. Mineo P.W. Shaul HDL stimulation of endothelial nitric oxide synthase: A novel mechanism of HDL action Trends Cardiovasc. Med. 13 2003 226-231
-
(2003)
Trends Cardiovasc. Med.
, vol.13
, pp. 226-231
-
-
Mineo, C.1
Shaul, P.W.2
-
35
-
-
0036392090
-
Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages
-
C. Langer et al. Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages Biochem. Biophys. Res. Commun. 296 2002 1051-1057
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1051-1057
-
-
Langer, C.1
-
36
-
-
0037396460
-
Androgens and coronary artery disease
-
F.C.W. Wu A. von Eckardstein Androgens and coronary artery disease Endocrine Rev 24 2003 183-217
-
(2003)
Endocrine Rev
, vol.24
, pp. 183-217
-
-
Wu, F.C.W.1
von Eckardstein, A.2
-
37
-
-
0032941071
-
Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism
-
F. Rinninger et al. Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism Arterioscler. Thromb. Vasc. Biol. 19 1999 1325-1332
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1325-1332
-
-
Rinninger, F.1
-
38
-
-
0037177140
-
High-density lipoprotein restores endothelial function in hypercholesterolemic men
-
L.E. Spieker et al. High-density lipoprotein restores endothelial function in hypercholesterolemic men Circulation 105 2002 1399-1402
-
(2002)
Circulation
, vol.105
, pp. 1399-1402
-
-
Spieker, L.E.1
-
39
-
-
0038311032
-
Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein
-
R.J. Bisoendial et al. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein Circulation 107 2003 2944-2948
-
(2003)
Circulation
, vol.107
, pp. 2944-2948
-
-
Bisoendial, R.J.1
-
40
-
-
0037396814
-
Apolipoprotein A-I(Milano): Current perspectives
-
G. Chiesa C.R. Sirtori Apolipoprotein A-I(Milano): Current perspectives Curr. Opin. Lipidol. 14 2003 159-163
-
(2003)
Curr. Opin. Lipidol.
, vol.14
, pp. 159-163
-
-
Chiesa, G.1
Sirtori, C.R.2
-
41
-
-
0038012797
-
Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries
-
S. Kaul et al. Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries Circulation 107 2003 2551-2554
-
(2003)
Circulation
, vol.107
, pp. 2551-2554
-
-
Kaul, S.1
-
42
-
-
0242577955
-
Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial
-
S.E. Nissen et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial J. Am. Med. Assoc. 290 2003 2292-2300
-
(2003)
J. Am. Med. Assoc.
, vol.290
, pp. 2292-2300
-
-
Nissen, S.E.1
-
43
-
-
0037154287
-
Oral administration of an Apo A-I mimetic peptide synthesized from d-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol
-
M. Navab et al. Oral administration of an Apo A-I mimetic peptide synthesized from d -amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol Circulation 105 2002 290-292
-
(2002)
Circulation
, vol.105
, pp. 290-292
-
-
Navab, M.1
-
44
-
-
4544383898
-
Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice
-
M. Navab et al. Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice Circulation 109 2004 3215-3220
-
(2004)
Circulation
, vol.109
, pp. 3215-3220
-
-
Navab, M.1
-
45
-
-
11144356028
-
HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3
-
J.R. Nofer et al. HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3 J. Clin. Invest. 113 2004 569-581
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 569-581
-
-
Nofer, J.R.1
-
46
-
-
2642526387
-
High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease
-
L. Rohrer et al. High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease Curr. Opin. Lipidol. 15 2004 269-278
-
(2004)
Curr. Opin. Lipidol.
, vol.15
, pp. 269-278
-
-
Rohrer, L.1
-
47
-
-
3042743990
-
FTY720: Sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function
-
V. Brinkmann et al. FTY720: Sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function Am. J. Transplant. 4 2004 1019-1025
-
(2004)
Am. J. Transplant.
, vol.4
, pp. 1019-1025
-
-
Brinkmann, V.1
-
48
-
-
2542462552
-
Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic subjects: A 12-week, double-blind, placebo-controlled dose-ranging study with an open pioglitazone arm
-
M.F. Saad et al. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic subjects: A 12-week, double-blind, placebo-controlled dose-ranging study with an open pioglitazone arm Diabetes Care 27 2004 1324-1329
-
(2004)
Diabetes Care
, vol.27
, pp. 1324-1329
-
-
Saad, M.F.1
-
49
-
-
2342644036
-
Antidiabetic and hypolipidemic potential of DRF 2519 - A dual activator of PPAR-alpha and PPAR-gamma
-
R. Chakrabarti et al. Antidiabetic and hypolipidemic potential of DRF 2519-a dual activator of PPAR-alpha and PPAR-gamma Eur. J. Pharmacol. 491 2004 195-206
-
(2004)
Eur. J. Pharmacol.
, vol.491
, pp. 195-206
-
-
Chakrabarti, R.1
-
50
-
-
11144355905
-
MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities
-
T.W. Doebber et al. MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities Biochem. Biophys. Res. Commun. 318 2004 323-328
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 323-328
-
-
Doebber, T.W.1
-
51
-
-
3042634455
-
Peroxisome proliferator-activated receptor (ppar) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo - A study using the Novel PPAR alpha/gamma Agonist Tesaglitazar
-
B.D. Hegarty et al. peroxisome proliferator-activated receptor (ppar) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo - a study using the Novel PPAR alpha/gamma Agonist Tesaglitazar Endocrinology 145 2004 3158-3164
-
(2004)
Endocrinology
, vol.145
, pp. 3158-3164
-
-
Hegarty, B.D.1
-
52
-
-
1842557516
-
Zinc finger protein ZNF202 structure and function in transcriptional control of HDL metabolism
-
G. Schmitz et al. Zinc finger protein ZNF202 structure and function in transcriptional control of HDL metabolism Curr. Opin. Lipidol. 15 2004 199-208
-
(2004)
Curr. Opin. Lipidol.
, vol.15
, pp. 199-208
-
-
Schmitz, G.1
-
53
-
-
1642268123
-
Treating obesity: Pharmacology of energy expenditure
-
J.C. Clapham Treating obesity: Pharmacology of energy expenditure Curr. Drug Targets 5 2004 309-323
-
(2004)
Curr. Drug Targets
, vol.5
, pp. 309-323
-
-
Clapham, J.C.1
-
55
-
-
2942556913
-
Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-Lipids and cardiac resynchronisation therapy in heart failure
-
J.G. Cleland et al. Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-Lipids and cardiac resynchronisation therapy in heart failure Eur. J. Heart Fail. 6 2004 501-508
-
(2004)
Eur. J. Heart Fail.
, vol.6
, pp. 501-508
-
-
Cleland, J.G.1
|