Regulation of cholesterol 7α-hydroxylase mRNA expression in C57BL/6 mice fed an atherogenic diet

Atherosclerosis

Volumn 178, Issue 2, 2005, Pages 265-269

  Ando, Hitoshi ^a   Tsuruoka, Shuichi ^a   Yamamoto, Hisashi ^a   Takamura, Toshinari ^b   Kaneko, Shuichi ^b   Fujimura, Akio ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

ATP binding cassette transporter A1; Cholic acid; CYP7A1; Farnesoid X receptor; Liver X receptor; Short heterodimer partner

Indexed keywords

CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; ABC TRANSPORTER; CELL RECEPTOR; DNA BINDING PROTEIN; FARNESOID X RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; LIVER X RECEPTOR; MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENIC DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIET; GENE TARGETING; GENETIC TRANSCRIPTION; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION REGULATION; PHYSIOLOGY;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLIC ACID; DIET, ATHEROGENIC; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 13244258525     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.09.016     Document Type: Article

References (30)

1. J.Y. Chiang Bile acid regulation of gene expression: roles of nuclear hormone receptors Endocr Rev 23 2002 443 463
2. D.F. Jelinek, S. Andersson, C.A. Slaughter, and D.W. Russell Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis J Biol Chem 265 1990 8190 8197
3. W.M. Pandak, Y.C. Li, and J.Y. Chiang Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat J Biol Chem 266 1991 3416 3421
4. S. Shefer, L.B. Nguyen, and G. Sal en Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat J Lipid Res 33 1992 1193 1200
5. D.K. Spady, and J.A. Cuthbert Regulation of hepatic sterol metabolism in the rat. Parallel regulation of activity and mRNA for 7 alpha-hydroxylase but not 3-hydroxy-3-methylglutaryl-coenzyme. A reductase or low density lipoprotein receptor J Biol Chem 267 1992 5584 5591
6. L. Rudel, C. Deckelman, M. Wilson, M. Scobey, and R. Anderson Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys J Clin Invest 93 1994 2463 3472
7. J.D. Horton, J.A. Cuthbert, and D.K. Spady Regulation of hepatic 7 alpha-hydroxylase expression and response to dietary cholesterol in the rat and hamster J Biol Chem 270 1995 5381 5387
8. G. Xu, G. Salen, and S. Shefer Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits J Clin Invest 95 1995 1497 1504
9. L.B. Nguyen, G. Xu, and S. Shefer Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7alpha-hydroxylase activities in the rat, guinea pig, and rabbit: effects of cholesterol and bile acids Metabolism 48 1999 1542 1548
10. S. Gupta, W.M. Pandak, and P.B. Hylemon LXR alpha is the dominant regulator of CYP7A1 transcription Biochem Biophys Res Commun 293 2002 338 343
11. G. Xu, H. Li, L.X. Pan, Q. Shang, A. Honda, and M. Ananthanarayanan FXR-mediated down-regulation of CYP7A1 dominates LXRalpha in long-term cholesterol-fed NZW rabbits J Lipid Res 44 2003 1956 1962
12. A. Roberts, and J.S. Thompson Genetic factors in the development of atheroma and on serum total cholesterol levels in inbred mice and their hybrids Prog Biochem Pharmacol 13 1977 298 305
13. B. Paigen, A. Morrow, C. Brandon, D. Mitchell, and P. Holmes Variation in susceptibility to atherosclerosis among inbred strains of mice Atherosclerosis 57 1985 65 73
14. G. Xu, L.X. Pan, and H. Li Dietary cholesterol stimulates CYP7A1 in rats because farnesoid X receptor is not activated Am J Physiol Gastrointest Liver Physiol 286 2004 G730 G735
15. S. Ishibashi, J. Herz, N. Maeda, J.L. Goldstein, and M.S. Brown The two-receptor model of lipoprotein clearance: tests of the hypothesis in 'knockout' mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins Proc Natl Acad Sci USA 91 1994 4431 4435
16. J.D. Horton, Y. Bashmakov, I. Shimomura, and H. Shimano Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice Proc Natl Acad Sci USA 95 1998 5987 5992
17. T.P. Carr, C.J. Andresen, and L.L. Rudel Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts Clin Biochem 26 1993 39 42
18. H. Ando, S. Tsuruoka, and H. Yamamoto Effects of pravastatin on the expression of ATP-binding cassette transporter A1 J Pharmacol Exp Ther 311 2004 420 425
19. Y.R. Su, M.F. Linton, and S. Fazio Rapid quantification of murine ABC mRNAs by real time reverse transcriptase-polymerase chain reaction J Lipid Res 43 2002 2180 2187
20. N. Wang, and A.R. Tall Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux Arterioscler Thromb Vasc Biol 23 2003 1178 1184
21. M. Trauner, and J.L. Boyer Bile salt transporters: molecular characterization, function, and regulation Physiol Rev 83 2003 633 671
22. B. Goodwin, S.A. Jones, and R.R. Price A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis Mol Cell 6 2000 517 526
23. T.T. Lu, M. Makishima, and J.J. Repa Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors Mol Cell 6 2000 507 515
24. J.L. Staudinger, B. Goodwin, and S.A. Jones The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity Proc Natl Acad Sci USA 98 2001 3369 3374
25. C.J. Sinal, M. Tohkin, and M. Miyata Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis Cell 2000 731 744
26. T.A. Kerr, S. Saeki, and M. Schneider Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis Dev Cell 2 2002 713 720
27. L. Wang, Y.K. Lee, and D. Bundman Redundant pathways for negative feedback regulation of bile acid production Dev Cell 2 2002 721 731
28. B. Goodwin, M.A. Watson, and H. Kim Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha Mol Endocrinol 17 2003 386 394
29. H.R. Kast, C.M. Nguyen, and C.J. Sinal Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids Mol Endocrinol 15 2001 1720 1728
30. I.P. Torra, T. Claudel, and C. Duval Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor Mol Endocrinol 17 2003 259 272