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Volumn 16, Issue 5, 1997, Pages 318-326

Patterns of T-cell repopulation, virus load reduction, and restoration of T-cell function in HIV-infected persons during therapy with different antiretroviral agents

Author keywords

Antiviral therapy; CD4 lymphocytes; HIV 1; T cell function; Viral RNA load

Indexed keywords

ANTIGEN P24; CD4 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY CD3; NEVIRAPINE; RITONAVIR; VIRUS RNA; ZIDOVUDINE;

EID: 13144306121     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199712150-00002     Document Type: Article
Times cited : (85)

References (41)
  • 1
    • 0023150577 scopus 로고
    • Predictors of the acquied immunodeficiency syndrome developing in a cohort of seropositive homosexual men
    • Polk BF, Fox R, Brookmeyer R, et al. Predictors of the acquied immunodeficiency syndrome developing in a cohort of seropositive homosexual men. N Engl J Med 1987;316:61-6.
    • (1987) N Engl J Med , vol.316 , pp. 61-66
    • Polk, B.F.1    Fox, R.2    Brookmeyer, R.3
  • 2
    • 0025069873 scopus 로고
    • The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1
    • Fahey JL, Taylor JMG, Detels R, et al. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med 1990;322:166-72.
    • (1990) N Engl J Med , vol.322 , pp. 166-172
    • Fahey, J.L.1    Taylor, J.M.G.2    Detels, R.3
  • 3
    • 0022652207 scopus 로고
    • Long-term seropositivity for human T-lymphotropic virus type III in homosexual men without the acquired immunodeficiency syndrome: Development of immunologic and clinical abnormalities
    • Melbye M, Biggar RJ, Ebbesen P, et al. Long-term seropositivity for human T-lymphotropic virus type III in homosexual men without the acquired immunodeficiency syndrome: development of immunologic and clinical abnormalities. Ann Intern Med 1986;104: 496-500.
    • (1986) Ann Intern Med , vol.104 , pp. 496-500
    • Melbye, M.1    Biggar, R.J.2    Ebbesen, P.3
  • 4
    • 0027430660 scopus 로고
    • Enhanced expression of human immunodeficiency virus type 1 correlates with development of AIDS
    • Gupta P, Kingsley L, Armstrong J, Ming Ding, Cottrill M, Rinaldo C. Enhanced expression of human immunodeficiency virus type 1 correlates with development of AIDS. Virology 1993;196:586-95.
    • (1993) Virology , vol.196 , pp. 586-595
    • Gupta, P.1    Kingsley, L.2    Armstrong, J.3    Ding, M.4    Cottrill, M.5    Rinaldo, C.6
  • 6
    • 0027410369 scopus 로고
    • High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR
    • Piatak M, Jr., Saag MS, Yang LC, et al. High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science 1993;259:1749-54.
    • (1993) Science , vol.259 , pp. 1749-1754
    • Piatak Jr., M.1    Saag, M.S.2    Yang, L.C.3
  • 7
    • 0028909872 scopus 로고
    • Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion
    • Mellors JW, Kingsley L, Rinaldo CR, Jr., et al. Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann Intern Med 1995;122:573-9.
    • (1995) Ann Intern Med , vol.122 , pp. 573-579
    • Mellors, J.W.1    Kingsley, L.2    Rinaldo Jr., C.R.3
  • 9
    • 0029081506 scopus 로고
    • Natural history of HIV-1 cell-free viremia
    • Henrard DR, Phillips JF, Muenz LR, et al. Natural history of HIV-1 cell-free viremia. JAMA 1995;274:554-8.
    • (1995) JAMA , vol.274 , pp. 554-558
    • Henrard, D.R.1    Phillips, J.F.2    Muenz, L.R.3
  • 10
    • 0028810243 scopus 로고
    • HIV-1 messenger RNA in peripheral blood mononuclear cells as an early marker of risk for progression to AIDS
    • Saksela K, Stevens CE, Rubinstein P, Taylor PE, Baltimore D. HIV-1 messenger RNA in peripheral blood mononuclear cells as an early marker of risk for progression to AIDS. Ann Intern Med 1995;123:641-8.
    • (1995) Ann Intern Med , vol.123 , pp. 641-648
    • Saksela, K.1    Stevens, C.E.2    Rubinstein, P.3    Taylor, P.E.4    Baltimore, D.5
  • 11
    • 0029683640 scopus 로고    scopus 로고
    • Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study
    • O'Brien TR, Blattner WA, Waters D, et al. Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study. JAMA 1996;276:105-10.
    • (1996) JAMA , vol.276 , pp. 105-110
    • O'Brien, T.R.1    Blattner, W.A.2    Waters, D.3
  • 12
    • 0029899473 scopus 로고    scopus 로고
    • HIV-1 RNA levels and the development of clinical disease
    • Phillips AN, Eron JJ, Bartlett JA, et al. HIV-1 RNA levels and the development of clinical disease. AIDS 1996;10:859-65.
    • (1996) AIDS , vol.10 , pp. 859-865
    • Phillips, A.N.1    Eron, J.J.2    Bartlett, J.A.3
  • 13
    • 0345334246 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1996
    • Carpenter CCJ, Fischl MA, Hammer SM, et al. Antiretroviral therapy for HIV infection in 1996. JAMA 1996;276:146-54.
    • (1996) JAMA , vol.276 , pp. 146-154
    • Carpenter, C.C.J.1    Fischl, M.A.2    Hammer, S.M.3
  • 14
    • 0028806725 scopus 로고
    • A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection
    • Markowitz M, Saag MS, Powderly WG, et al. A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. N Engl J Med 1995;333:1534-40.
    • (1995) N Engl J Med , vol.333 , pp. 1534-1540
    • Markowitz, M.1    Saag, M.S.2    Powderly, W.G.3
  • 15
    • 0028846165 scopus 로고
    • A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease
    • Danner SA, Carr A, Leonard JM, et al. A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. N Engl J Med 1995;333:1528-33.
    • (1995) N Engl J Med , vol.333 , pp. 1528-1533
    • Danner, S.A.1    Carr, A.2    Leonard, J.M.3
  • 16
    • 0025257356 scopus 로고
    • Low T-cell responsiveness to activation via CD3/TCR is a prognostic marker for AIDS in HIV-1 infected men
    • Schellekens PThA, Roos MThL, De Wolf F, Lange JMA, Miedema F. Low T-cell responsiveness to activation via CD3/TCR is a prognostic marker for AIDS in HIV-1 infected men. J. Clin Immunol 1990;10:121-7.
    • (1990) J. Clin Immunol , vol.10 , pp. 121-127
    • Schellekens, P.Th.A.1    Roos, M.Th.L.2    De Wolf, F.3    Lange, J.M.A.4    Miedema, F.5
  • 17
    • 0028168943 scopus 로고
    • Changing virus-host interactions in the course of HIV-1 infection
    • Miedema F, Meyaard L, Koot M, et al. Changing virus-host interactions in the course of HIV-1 infection. Immunol Rev 1994;140: 35-72.
    • (1994) Immunol Rev , vol.140 , pp. 35-72
    • Miedema, F.1    Meyaard, L.2    Koot, M.3
  • 18
    • 0029003494 scopus 로고
    • The predictive value of T cell function in vitro and pre AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam
    • Bindels PJE, Krol A, Roos MThL, et al. The predictive value of T cell function in vitro and pre AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam. J Infect Dis 1995;172:97-104.
    • (1995) J Infect Dis , vol.172 , pp. 97-104
    • Bindels, P.J.E.1    Krol, A.2    Roos, M.Th.L.3
  • 19
    • 0028926167 scopus 로고
    • T-cell function in vitro is an independent progression marker for AIDS in human immunodeficiency virus (HIV)-infected asymptomatic individuals
    • Roos MThL, Miedema F, Koot M, et al. T-cell function in vitro is an independent progression marker for AIDS in human immunodeficiency virus (HIV)-infected asymptomatic individuals. J Infect Dis 1995;171:531-6.
    • (1995) J Infect Dis , vol.171 , pp. 531-536
    • Roos, M.Th.L.1    Miedema, F.2    Koot, M.3
  • 20
    • 9844249672 scopus 로고    scopus 로고
    • + T cell count and function: Markers with reciprocal predictive value over time after seroconversion
    • in press
    • + T cell count and function: Markers with reciprocal predictive value over time after seroconversion. AIDS 1997, in press.
    • (1997) AIDS
    • De Wolf, F.1    Spijkerman, I.2    Schellekens, P.Th.A.3
  • 21
    • 0030317890 scopus 로고    scopus 로고
    • Viral dynamics of HIV: Implications for drug development and therapeutic strategies
    • Havlir D, Richman DD. Viral dynamics of HIV: Implications for drug development and therapeutic strategies. Ann Intent Med 1996;124:984-94.
    • (1996) Ann Intent Med , vol.124 , pp. 984-994
    • Havlir, D.1    Richman, D.D.2
  • 22
    • 0026714667 scopus 로고
    • Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients
    • Clerici M, Landay AL, Kessler HA, et al. Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients. J Infect Dis 1992;166: 723-30.
    • (1992) J Infect Dis , vol.166 , pp. 723-730
    • Clerici, M.1    Landay, A.L.2    Kessler, H.A.3
  • 23
    • 0026788364 scopus 로고
    • Changes in T-helper cell function in human immunodeficiency virus infected children during didanosine therapy as a measure of antiretroviral activity
    • Clerici M, Roilides E, Butler KM, et al. Changes in T-helper cell function in human immunodeficiency virus infected children during didanosine therapy as a measure of antiretroviral activity. Blood 1992;80:2196-202.
    • (1992) Blood , vol.80 , pp. 2196-2202
    • Clerici, M.1    Roilides, E.2    Butler, K.M.3
  • 24
    • 0025973367 scopus 로고
    • Differences in clinical course in zidovudine-treated asymptomatic HIV-infected men associated with T-cell function at intake
    • Gruters RA, Terpstra FG, Lange JMA, et al. Differences in clinical course in zidovudine-treated asymptomatic HIV-infected men associated with T-cell function at intake. AIDS 1991;5:43-7.
    • (1991) AIDS , vol.5 , pp. 43-47
    • Gruters, R.A.1    Terpstra, F.G.2    Lange, J.M.A.3
  • 25
    • 0027225949 scopus 로고
    • Viral phenotype and T-cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine
    • Koot M, Schellekens PThA, Mulder JW, et al. Viral phenotype and T-cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine. J Infect Dis 1993;168: 733-6.
    • (1993) J Infect Dis , vol.168 , pp. 733-736
    • Koot, M.1    Schellekens, P.Th.A.2    Mulder, J.W.3
  • 26
    • 0028347345 scopus 로고
    • Zidovudine twice daily in asymptomatic subjects with HIV infection and a high risk of progression to AIDS: A randomized, double-blind placebo-controlled study
    • Mulder JW, Cooper DA, Mathiesen L, et al. Zidovudine twice daily in asymptomatic subjects with HIV infection and a high risk of progression to AIDS: a randomized, double-blind placebo-controlled study. AIDS 1994;8:313-21.
    • (1994) AIDS , vol.8 , pp. 313-321
    • Mulder, J.W.1    Cooper, D.A.2    Mathiesen, L.3
  • 27
    • 16944364799 scopus 로고    scopus 로고
    • High-dose nevirapine in previously untreated human immunodeficiency virus type 1-infected persons does not result in sustained suppression of viral replication
    • De Jong MD, Vella S, Carr A, et al. High-dose nevirapine in previously untreated human immunodeficiency virus type 1-infected persons does not result in sustained suppression of viral replication. J Infect Dis 1997;175:966-70.
    • (1997) J Infect Dis , vol.175 , pp. 966-970
    • De Jong, M.D.1    Vella, S.2    Carr, A.3
  • 30
    • 0023850566 scopus 로고
    • Signals involved in T-cell activation. T-cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies
    • Van Lier RAW, Brouwer M, Aarden LA. Signals involved in T-cell activation. T-cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies. Eur J Immunol 1988;18:167-72.
    • (1988) Eur J Immunol , vol.18 , pp. 167-172
    • Van Lier, R.A.W.1    Brouwer, M.2    Aarden, L.A.3
  • 31
    • 0028069547 scopus 로고
    • A rapid and simple PCR assay for quantification of human immunodeficiency virus type-1 RNA in plasma; application to acute retroviral infection
    • Mulder J, McKinney N, Christopherson C, Sninsky J, Greenfield L, Kwok S. A rapid and simple PCR assay for quantification of human immunodeficiency virus type-1 RNA in plasma; application to acute retroviral infection. J Clin Microbiol 1994;32:292-300.
    • (1994) J Clin Microbiol , vol.32 , pp. 292-300
    • Mulder, J.1    McKinney, N.2    Christopherson, C.3    Sninsky, J.4    Greenfield, L.5    Kwok, S.6
  • 32
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type-1 selected during therapy
    • Richman DD, Havlir D, Corbeil J, et al. Nevirapine resistance mutations of human immunodeficiency virus type-1 selected during therapy. J Virol 1994;68:1660-6.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.D.1    Havlir, D.2    Corbeil, J.3
  • 33
    • 0026570624 scopus 로고
    • Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects
    • Boucher CAB, O'Sullivan E, Mulder JW, et al. Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects. J Infect Dis 1992;165:105-10.
    • (1992) J Infect Dis , vol.165 , pp. 105-110
    • Boucher, C.A.B.1    O'Sullivan, E.2    Mulder, J.W.3
  • 34
    • 0030012398 scopus 로고    scopus 로고
    • Resistance related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538)
    • Schmit J, Ruiz L, Clotet B, et al. Resistance related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538) AIDS 1996;10:995-9.
    • (1996) AIDS , vol.10 , pp. 995-999
    • Schmit, J.1    Ruiz, L.2    Clotet, B.3
  • 35
    • 0029980114 scopus 로고    scopus 로고
    • Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid chage in reverse transcriptase are responsible for the loss of HIV-1 RNA load suppression by zidovudine
    • De Jong MD, Veenstra J, Stilianakis NI, et al. Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid chage in reverse transcriptase are responsible for the loss of HIV-1 RNA load suppression by zidovudine. Proc Natl Acad Sci USA 1996;93:5501-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5501-5506
    • De Jong, M.D.1    Veenstra, J.2    Stilianakis, N.I.3
  • 36
    • 0029009021 scopus 로고
    • T cell dynamics of immunodeficiency
    • Roederer M. T cell dynamics of immunodeficiency. Nature Med 1995;1:621-2.
    • (1995) Nature Med , vol.1 , pp. 621-622
    • Roederer, M.1
  • 39
    • 0030052964 scopus 로고    scopus 로고
    • Alterations in the immune response of human immunodeficiency virus (HIV) infected subjects treated with an HIV-specific protease inhibitor, ritonavir
    • Kelleher AD, Carr A, Zaunders J, Cooper DA. Alterations in the immune response of human immunodeficiency virus (HIV) infected subjects treated with an HIV-specific protease inhibitor, ritonavir. J Infect Dis 1996;173:321-9.
    • (1996) J Infect Dis , vol.173 , pp. 321-329
    • Kelleher, A.D.1    Carr, A.2    Zaunders, J.3    Cooper, D.A.4
  • 40
    • 0023934039 scopus 로고
    • Human naive and memory T cells: Reinterpretation of helper-inducer and suppressor-inducer subsets
    • Sanders ME, Makgoba MW, Shaw S. Human naive and memory T cells: reinterpretation of helper-inducer and suppressor-inducer subsets. Immunol Today 1988;9:195-8.
    • (1988) Immunol Today , vol.9 , pp. 195-198
    • Sanders, M.E.1    Makgoba, M.W.2    Shaw, S.3


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